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Tag Content
iUUCD ID IUUC-Dre-028346
Ensembl Protein ID ENSDARP00000131820.1
UniProt Accession Q566T0; A8E5D5; EED_DANRE
Genbank Protein ID AAH93351.1; AAI53557.1
Protein Name Polycomb protein eed
Genbank Nucleotide ID BC093351; BC153556
Gene Name eed; zgc:112509
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000099640.1 ENSDART00000162928.1 ENSDARP00000131820.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 5.50e-15 55.8 236 271
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgv 34
    gH d+v + +f + + s++ D+++k+W+l++ +
   Q: 236 GHRDEVLSADFdlLGEKIMSCGMDHSLKLWRLDSER 271
    8**********875588**************98876 PP
   

Organism Danio rerio
Functional Description
(View)

Functional Description



     Polycomb group (PcG) protein. Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity).
Polycomb group (PcG) protein. Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity).
Protein Sequence
(Fasta)
MKMRRKMSEP HGEAGNEMPN KKQKLSSDEN SNPDLSGDDN DDAVSVESGT HPERPDTPTN 60
TASAPGRKSW GKGKWKSKKC KYSFKCVNSL KEDHGQPLFG VQFNWHSKEG DPLVFATVGS 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Dre-028346|E3,WD_repeat|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CACTATAGGG ATTAGGGACC TAGTGAGCGC TTTTGGACAC CGCCGCGTGT CTCCCTCTGC 60
TGCCGATCCG CTTTACTGCA GCTGTCGTGC TGTTTTGCGA CAGTGTGGCG CGGATGTTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Dre-028346|E3,WD_repeat|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0035098--C:ESC/E(Z) complex
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000689 Aegilops tauschii 41.93 2.00e-76 279.00
IUUC-Aml-001510 Ailuropoda melanoleuca 90.76 0.00e+00 773.00
IUUC-Atr-002496 Amborella trichopoda 40.69 6.00e-69 254.00
IUUC-Apl-003768 Anas platyrhynchos 92.29 0.00e+00 786.00
IUUC-Aca-004382 Anolis carolinensis 92.92 0.00e+00 782.00
IUUC-Aly-005980 Arabidopsis lyrata 41.03 1.00e-74 273.00
IUUC-Ath-006579 Arabidopsis thaliana 41.03 2.00e-74 272.00
IUUC-Ame-010987 Astyanax mexicanus 95.01 0.00e+00 832.00
IUUC-Bta-013432 Bos taurus 91.42 0.00e+00 785.00
IUUC-Bci-013970 Botrytis cinerea 33.47 3.00e-30 126.00
IUUC-Bdi-014553 Brachypodium distachyon 43.63 2.00e-78 286.00
IUUC-Bol-016522 Brassica oleracea 40.55 5.00e-74 271.00
IUUC-Bra-017137 Brassica rapa 40.55 4.00e-74 271.00
IUUC-Cel-018494 Caenorhabditis elegans 24.36 7.00e-29 121.00
IUUC-Cja-019066 Callithrix jacchus 91.42 0.00e+00 785.00
IUUC-Cfa-021261 Canis familiaris 91.42 0.00e+00 785.00
IUUC-Cpo-022375 Cavia porcellus 85.61 0.00e+00 720.00
IUUC-Csa-024005 Chlorocebus sabaeus 91.42 0.00e+00 785.00
IUUC-Cho-024881 Choloepus hoffmanni 79.34 2.00e-143 502.00
IUUC-Cin-025697 Ciona intestinalis 62.18 3.00e-144 504.00
IUUC-Csv-026221 Ciona savignyi 64.43 5.00e-148 517.00
IUUC-Cgl-026519 Colletotrichum gloeosporioides 26.82 3.00e-24 106.00
IUUC-Cne-026877 Cryptococcus neoformans 29.34 6.00e-27 115.00
IUUC-Cme-027353 Cyanidioschyzon merolae 44.14 1.00e-32 134.00
IUUC-Dno-029319 Dasypus novemcinctus 91.18 0.00e+00 785.00
IUUC-Dor-030746 Dipodomys ordii 64.25 3.00e-163 568.00
IUUC-Dse-031324 Dothistroma septosporum 26.87 2.00e-27 117.00
IUUC-Dme-032029 Drosophila melanogaster 59.73 1.00e-134 473.00
IUUC-Ete-032880 Echinops telfairi 75.54 2.00e-121 429.00
IUUC-Eca-034272 Equus caballus 92.06 0.00e+00 741.00
IUUC-Eeu-035303 Erinaceus europaeus 85.93 0.00e+00 758.00
IUUC-Fca-036008 Felis catus 92.20 0.00e+00 780.00
IUUC-Fal-037577 Ficedula albicollis 92.80 0.00e+00 748.00
IUUC-Fso-038294 Fusarium solani 25.58 1.00e-26 114.00
IUUC-Gmo-039008 Gadus morhua 91.49 0.00e+00 789.00
IUUC-Ggr-039894 Gaeumannomyces graminis 31.25 1.00e-24 108.00
IUUC-Gga-040859 Gallus gallus 92.45 0.00e+00 781.00
IUUC-Gac-041667 Gasterosteus aculeatus 87.61 0.00e+00 774.00
IUUC-Gma-043832 Glycine max 40.44 4.00e-75 275.00
IUUC-Ggo-045624 Gorilla gorilla 86.40 0.00e+00 770.00
IUUC-Hsa-046505 Homo sapiens 91.42 0.00e+00 785.00
IUUC-Hvu-047228 Hordeum vulgare 38.30 3.00e-33 134.00
IUUC-Itr-048381 Ictidomys tridecemlineatus 91.42 0.00e+00 786.00
IUUC-Lch-050492 Latimeria chalumnae 92.24 0.00e+00 808.00
IUUC-Lpe-050807 Leersia perrieri 38.33 1.00e-73 270.00
IUUC-Loc-052361 Lepisosteus oculatus 93.65 0.00e+00 825.00
IUUC-Lma-053058 Leptosphaeria maculans 26.90 2.00e-20 94.00
IUUC-Laf-053941 Loxodonta africana 84.69 0.00e+00 739.00
IUUC-Mcc-055518 Macaca mulatta 86.40 0.00e+00 770.00
IUUC-Mor-056944 Magnaporthe oryzae 26.87 6.00e-27 115.00
IUUC-Mtr-058716 Medicago truncatula 42.08 7.00e-70 257.00
IUUC-Mga-059469 Meleagris gallopavo 92.45 0.00e+00 782.00
IUUC-Mmr-061026 Microcebus murinus 86.18 0.00e+00 769.00
IUUC-Mdo-062346 Monodelphis domestica 90.72 0.00e+00 784.00
IUUC-Mmu-063785 Mus musculus 91.42 0.00e+00 785.00
IUUC-Mac-064681 Musa acuminata 41.30 2.00e-78 285.00
IUUC-Mpu-066862 Mustela putorius furo 91.42 0.00e+00 785.00
IUUC-Mlu-067103 Myotis lucifugus 86.10 0.00e+00 680.00
IUUC-Ncr-068782 Neurospora crassa 31.62 3.00e-26 113.00
IUUC-Nle-069472 Nomascus leucogenys 91.42 0.00e+00 785.00
IUUC-Opr-070376 Ochotona princeps 88.65 2.00e-115 409.00
IUUC-Ont-071513 Oreochromis niloticus 92.33 0.00e+00 840.00
IUUC-Oan-073202 Ornithorhynchus anatinus 92.06 0.00e+00 745.00
IUUC-Ocu-074012 Oryctolagus cuniculus 91.18 0.00e+00 784.00
IUUC-Oba-075030 Oryza barthii 43.32 3.00e-81 295.00
IUUC-Obr-076895 Oryza brachyantha 42.78 4.00e-79 288.00
IUUC-Ogl-077522 Oryza glaberrima 43.61 1.00e-80 293.00
IUUC-Ogu-078250 Oryza glumaepatula 39.12 4.00e-69 255.00
IUUC-Oin-079886 Oryza indica 43.05 1.00e-80 293.00
IUUC-Olo-080238 Oryza longistaminata 43.32 4.00e-81 295.00
IUUC-Ome-081204 Oryza meridionalis 39.37 9.00e-68 251.00
IUUC-Oni-082388 Oryza nivara 39.45 8.00e-72 265.00
IUUC-Opu-083537 Oryza punctata 42.90 2.00e-79 289.00
IUUC-Oru-084863 Oryza rufipogon 39.39 7.00e-70 258.00
IUUC-Osa-085622 Oryza sativa 43.24 3.00e-81 295.00
IUUC-Ola-087426 Oryzias latipes 90.23 0.00e+00 816.00
IUUC-Olu-087788 Ostreococcus lucimarinus 30.17 5.00e-44 171.00
IUUC-Oga-088228 Otolemur garnettii 89.41 0.00e+00 785.00
IUUC-Oar-090139 Ovis aries 92.06 0.00e+00 741.00
IUUC-Pan-092874 Papio anubis 91.98 3.00e-148 517.00
IUUC-Psi-093927 Pelodiscus sinensis 92.06 0.00e+00 744.00
IUUC-Pma-094740 Petromyzon marinus 84.28 4.00e-140 490.00
IUUC-Pno-095072 Phaeosphaeria nodorum 25.56 2.00e-20 93.60
IUUC-Ppa-095871 Physcomitrella patens 40.38 2.00e-73 269.00
IUUC-Pfo-097208 Poecilia formosa 92.33 0.00e+00 844.00
IUUC-Pab-097658 Pongo abelii 91.42 0.00e+00 785.00
IUUC-Pop-098930 Populus trichocarpa 41.30 2.00e-77 282.00
IUUC-Ppe-101807 Prunus persica 40.92 4.00e-76 278.00
IUUC-Pva-103191 Pteropus vampyrus 78.29 0.00e+00 676.00
IUUC-Pgr-103619 Puccinia graminis 25.48 2.00e-19 90.50
IUUC-Pte-104406 Pyrenophora teres 28.38 1.00e-28 121.00
IUUC-Pyt-104821 Pyrenophora triticirepentis 26.53 2.00e-22 100.00
IUUC-Rno-105854 Rattus norvegicus 91.42 0.00e+00 785.00
IUUC-Sha-107426 Sarcophilus harrisii 88.74 0.00e+00 785.00
IUUC-Smo-109638 Selaginella moellendorffii 40.44 3.00e-75 275.00
IUUC-Sit-110481 Setaria italica 43.02 9.00e-79 287.00
IUUC-Sly-111464 Solanum lycopersicum 39.62 4.00e-74 271.00
IUUC-Stu-112910 Solanum tuberosum 39.62 4.00e-74 271.00
IUUC-Sar-113754 Sorex araneus 85.55 1.00e-177 615.00
IUUC-Sbi-114023 Sorghum bicolor 43.30 1.00e-79 290.00
IUUC-Ssc-115386 Sus scrofa 91.42 0.00e+00 785.00
IUUC-Tgu-117123 Taeniopygia guttata 92.29 0.00e+00 787.00
IUUC-Tru-117720 Takifugu rubripes 89.87 0.00e+00 823.00
IUUC-Tsy-119584 Tarsius syrichta 86.40 0.00e+00 771.00
IUUC-Tni-119695 Tetraodon nigroviridis 92.55 0.00e+00 837.00
IUUC-Tca-121787 Theobroma cacao 41.58 6.00e-77 281.00
IUUC-Tvi-122409 Trichoderma virens 25.00 6.00e-23 102.00
IUUC-Tae-124694 Triticum aestivum 41.93 5.00e-76 278.00
IUUC-Tme-126906 Tuber melanosporum 30.43 4.00e-35 142.00
IUUC-Tbe-127557 Tupaia belangeri 72.81 0.00e+00 655.00
IUUC-Vda-129774 Verticillium dahliae 25.66 5.00e-21 95.90
IUUC-Vpa-130256 Vicugna pacos 78.78 0.00e+00 662.00
IUUC-Vvi-131201 Vitis vinifera 42.01 8.00e-76 277.00
IUUC-Xtr-132206 Xenopus tropicalis 90.70 0.00e+00 801.00
IUUC-Xma-134102 Xiphophorus maculatus 92.10 0.00e+00 843.00
IUUC-Zma-135593 Zea mays 43.87 3.00e-80 291.00
Created Date 25-Jun-2017

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