iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021398

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02027809

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000013528.3	ENSCPOT00000013663.2	ENSCPOP00000012180.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-43	143.3	194	233
UBD/Beta-Prp	3.80e-53	180.6	189	395

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllks 38
           Ht+  ++++f  sd   ++++s+Dgt+ +WD+ +g ll+s
   Q: 194  HTNYLSACSFtnSDmQQILTASGDGTCALWDVESGQLLQS 233
           999999*****988999******************99986 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqclee 131
           +s+  h++  +a++f +++   ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++ 
   Q: 189  KSVAMHTNYLSACSFTNSDMqQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ- 276
           5668899999999998876559**************************************9777************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g  v +l 
   Q: 277  AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGVRVSILF 365
           *******************************************95333556778999******************************** PP
   S: 220  ghtdnvksvrfspnderlvsgssDgsiriW 249
           gh++ v+ +r+sp+++ + sgs D ++r+W
   Q: 366  GHENRVSTLRVSPDGTAFCSGSWDHTLRVW 395
           ****************************** PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RPLRPVFKKS QQLNYCSQCA EIMASDGLHE SETLAALRSE 60
AESLKGKLEE ERAKLHDVEL RQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCRDKRRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGACC AGACCTTTTT AGTGAACGTG TTTGGCTCCT GTGACAAATG CTTCAAACAG 60
AGACCTCTGA GACCGGTTTT CAAGAAATCC CAACAGCTCA ACTATTGCTC GCAATGCGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	91.41	0.00e+00	752.00
IUUC-Apl-003399	Anas platyrhynchos	97.45	0.00e+00	639.00
IUUC-Aca-004861	Anolis carolinensis	90.91	0.00e+00	761.00
IUUC-Ame-011851	Astyanax mexicanus	91.19	0.00e+00	676.00
IUUC-Bta-012438	Bos taurus	97.46	0.00e+00	717.00
IUUC-Cel-018408	Caenorhabditis elegans	65.03	4.00e-138	484.00
IUUC-Cja-019086	Callithrix jacchus	96.95	0.00e+00	796.00
IUUC-Cfa-021255	Canis familiaris	95.43	0.00e+00	742.00
IUUC-Csa-023776	Chlorocebus sabaeus	97.18	0.00e+00	715.00
IUUC-Cin-025305	Ciona intestinalis	57.56	6.00e-130	456.00
IUUC-Csv-026058	Ciona savignyi	57.45	1.00e-126	446.00
IUUC-Dre-028432	Danio rerio	84.60	0.00e+00	675.00
IUUC-Dno-029958	Dasypus novemcinctus	84.19	3.00e-142	497.00
IUUC-Dor-031013	Dipodomys ordii	98.44	7.00e-151	526.00
IUUC-Dme-031889	Drosophila melanogaster	68.21	2.00e-147	515.00
IUUC-Eca-033977	Equus caballus	91.41	0.00e+00	749.00
IUUC-Eeu-035079	Erinaceus europaeus	96.18	0.00e+00	782.00
IUUC-Fca-035693	Felis catus	90.20	0.00e+00	743.00
IUUC-Fal-037345	Ficedula albicollis	96.05	0.00e+00	712.00
IUUC-Gmo-039222	Gadus morhua	89.83	0.00e+00	647.00
IUUC-Gga-040320	Gallus gallus	96.05	0.00e+00	712.00
IUUC-Gac-042644	Gasterosteus aculeatus	89.83	0.00e+00	674.00
IUUC-Ggo-044489	Gorilla gorilla	92.95	0.00e+00	756.00
IUUC-Hsa-046434	Homo sapiens	96.97	0.00e+00	801.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	92.74	7.00e-174	602.00
IUUC-Loc-052790	Lepisosteus oculatus	89.57	0.00e+00	717.00
IUUC-Laf-054255	Loxodonta africana	96.19	0.00e+00	786.00
IUUC-Mcc-055610	Macaca mulatta	96.45	0.00e+00	791.00
IUUC-Meu-056819	Macropus eugenii	84.99	0.00e+00	679.00
IUUC-Mga-059740	Meleagris gallopavo	86.82	0.00e+00	711.00
IUUC-Mmr-061221	Microcebus murinus	96.97	0.00e+00	801.00
IUUC-Mdo-062619	Monodelphis domestica	96.61	0.00e+00	714.00
IUUC-Mmu-064266	Mus musculus	97.22	0.00e+00	804.00
IUUC-Mpu-065766	Mustela putorius furo	98.34	3.00e-179	620.00
IUUC-Mlu-067221	Myotis lucifugus	90.68	0.00e+00	748.00
IUUC-Nle-069515	Nomascus leucogenys	98.42	0.00e+00	649.00
IUUC-Opr-070195	Ochotona princeps	88.32	0.00e+00	709.00
IUUC-Ont-071535	Oreochromis niloticus	78.03	2.00e-170	591.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	4.00e-107	379.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.01	5.00e-180	622.00
IUUC-Ola-086578	Oryzias latipes	90.93	0.00e+00	639.00
IUUC-Oga-089090	Otolemur garnettii	96.73	0.00e+00	796.00
IUUC-Oar-090017	Ovis aries	91.37	0.00e+00	742.00
IUUC-Ptr-091280	Pan troglodytes	88.64	0.00e+00	712.00
IUUC-Pan-092198	Papio anubis	97.81	0.00e+00	649.00
IUUC-Psi-093030	Pelodiscus sinensis	85.11	0.00e+00	713.00
IUUC-Pma-094140	Petromyzon marinus	82.94	1.00e-103	368.00
IUUC-Pfo-097182	Poecilia formosa	90.68	0.00e+00	654.00
IUUC-Pab-098157	Pongo abelii	97.46	0.00e+00	719.00
IUUC-Pca-100988	Procavia capensis	76.77	3.00e-168	584.00
IUUC-Pva-102232	Pteropus vampyrus	85.19	7.00e-174	602.00
IUUC-Rno-105526	Rattus norvegicus	93.82	0.00e+00	680.00
IUUC-Sce-106298	Saccharomyces cerevisiae	36.32	2.00e-68	252.00
IUUC-Sha-106754	Sarcophilus harrisii	94.70	0.00e+00	742.00
IUUC-Ssc-115390	Sus scrofa	97.22	0.00e+00	808.00
IUUC-Tgu-117377	Taeniopygia guttata	86.55	0.00e+00	693.00
IUUC-Tru-117938	Takifugu rubripes	90.68	0.00e+00	642.00
IUUC-Tsy-119392	Tarsius syrichta	83.33	0.00e+00	653.00
IUUC-Tni-119834	Tetraodon nigroviridis	72.47	1.00e-164	572.00
IUUC-Tbe-127469	Tupaia belangeri	93.63	0.00e+00	714.00
IUUC-Ttr-128252	Tursiops truncatus	93.45	0.00e+00	758.00
IUUC-Vpa-130173	Vicugna pacos	79.53	3.00e-154	537.00
IUUC-Xtr-131803	Xenopus tropicalis	90.15	0.00e+00	719.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence