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Tag Content
UUCD2 ID IUUC-Pab-097849
UUCD1 version UUC-PoA-00245
Ensembl Protein ID ENSPPYP00000006809.2
UniProt Accession H2NLS7; H2NLS7_PONAB
Genbank Protein ID ENSPPYP00000006809
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABGA01098001
Gene Name AREL1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000005990.2 ENSPPYT00000007078.2 ENSPPYP00000006809.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.80e-101 339.9 485 822
Active Site
Position(s) Description Evidence
790 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.lysendketlqpnpdsglknpehlklFeflGrllgkalqdg..... 85
           sd++k++ev f++Ee+ld+gG+ re+++l++k+l++++++lf ++s+n+++ ++pnp++  +   +lk++ef+Grl+gk+l+++     
   Q: 485  SDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFtRFSDNNQALVHPNPNRPAH--LRLKMYEFAGRLVGKCLYESslgga 571
           7999**************************************888999***********975..9******************999999 PP
   S: 86   ..rlldlplsksfyklllgkklsledleevdpelyks.lkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNke 171
             +l+++++++sf+ +++g +++++ +e+ dpe+yks + +i++n   d++e++l ++ ++ +++ +  k++eL++gG+++pVtn+Nk 
   Q: 572  ykQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSkVCFILNN---DMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKI 657
           99***********************************99****99...9****9****9999999************************ PP
   S: 172  eYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkket.kykggytedspaiqwFwevleefsse 259
            Y +l+++yrl +++ke+ve+f +G+ne++p++ll++F+e+elell+cG+ +i+v+d+k ++    g ++ ++++++wFw v++++++e
   Q: 658  FYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKVHAvVVGGSWHFREKVMRWFWTVVSSLTQE 746
           **************************************************************555788999****************** PP
   S: 260  erkafLqFvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           e +++LqF+Tgss+lP+gGfa+l p++ +i    +++ lP+++TCfn+L+LP+Y+s+e+++++L++Ai+e+ +gF++
   Q: 747  ELARLLQFTTGSSQLPPGGFAALCPSFQIIAA-PTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGcEGFGM 822
           ************************99555555.**************************************9***97 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MFYVIGGITV SLVAFFFTIK FLFELAARVV SFLQNEDRER RGDRTIYDYV RGNYLDPRSC 60
KVSWDWKDPY EVGHSMAFRV HLFYKNGQPF PAHRPVGLRV HISHVELAVE IPVTQEVLQE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-097849|E3,HECT|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGGGCAGTTG ATTCCAGACA CTCACAGCCT CTGATCTCTG AGACTAAGCA TTCGCTTCAT 60
GGTCGCATAC TTCCTTGTTT TCTTTTGCTT CCCCTTGAAA CAGAAATTTT AGAATTAAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-097849|E3,HECT|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR017868--Filamin/ABP280_repeat-like
IPR000569--HECT_dom
IPR013783--Ig-like_fold
IPR014756--Ig_E-set
PROSITE

PS50194--FILAMIN_REPEAT
PS50237--HECT
Pfam

PF00630--Filamin
PF00632--HECT
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043066--P:negative regulation of apoptotic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG pon:100458842
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001308 Ailuropoda melanoleuca 97.45 0.00e+00 1641.00
IUUC-Apl-004071 Anas platyrhynchos 90.40 0.00e+00 1466.00
IUUC-Aca-005218 Anolis carolinensis 90.78 0.00e+00 1494.00
IUUC-Ame-011871 Astyanax mexicanus 79.71 0.00e+00 1385.00
IUUC-Bta-012978 Bos taurus 96.72 0.00e+00 1633.00
IUUC-Cja-019081 Callithrix jacchus 99.15 0.00e+00 1665.00
IUUC-Cfa-020736 Canis familiaris 94.88 0.00e+00 1543.00
IUUC-Cpo-021581 Cavia porcellus 96.96 0.00e+00 1632.00
IUUC-Csa-024189 Chlorocebus sabaeus 98.54 0.00e+00 945.00
IUUC-Cho-024751 Choloepus hoffmanni 96.11 0.00e+00 1551.00
IUUC-Cin-025773 Ciona intestinalis 42.49 1.00e-148 520.00
IUUC-Csv-026090 Ciona savignyi 40.44 1.00e-172 600.00
IUUC-Dre-027788 Danio rerio 80.19 0.00e+00 1389.00
IUUC-Dno-030022 Dasypus novemcinctus 97.33 0.00e+00 1636.00
IUUC-Dme-031577 Drosophila melanogaster 47.14 0.00e+00 727.00
IUUC-Ete-032402 Echinops telfairi 94.75 0.00e+00 1552.00
IUUC-Eca-033908 Equus caballus 98.42 0.00e+00 1655.00
IUUC-Eeu-034869 Erinaceus europaeus 98.06 0.00e+00 924.00
IUUC-Fca-036023 Felis catus 97.45 0.00e+00 1640.00
IUUC-Fal-037477 Ficedula albicollis 91.13 0.00e+00 1526.00
IUUC-Gmo-039197 Gadus morhua 80.19 0.00e+00 1365.00
IUUC-Gga-040704 Gallus gallus 90.89 0.00e+00 1514.00
IUUC-Gac-041511 Gasterosteus aculeatus 78.86 0.00e+00 1370.00
IUUC-Ggo-044527 Gorilla gorilla 96.12 0.00e+00 1595.00
IUUC-Hsa-046082 Homo sapiens 99.51 0.00e+00 1671.00
IUUC-Itr-048168 Ictidomys tridecemlineatus 97.45 0.00e+00 1643.00
IUUC-Lch-049772 Latimeria chalumnae 76.79 0.00e+00 1244.00
IUUC-Loc-052541 Lepisosteus oculatus 81.45 0.00e+00 1398.00
IUUC-Laf-053852 Loxodonta africana 97.21 0.00e+00 1632.00
IUUC-Mcc-054759 Macaca mulatta 99.31 0.00e+00 858.00
IUUC-Meu-056247 Macropus eugenii 77.85 0.00e+00 842.00
IUUC-Mga-060161 Meleagris gallopavo 90.05 0.00e+00 1496.00
IUUC-Mmr-061447 Microcebus murinus 97.81 0.00e+00 1644.00
IUUC-Mdo-062110 Monodelphis domestica 94.29 0.00e+00 1536.00
IUUC-Mmu-064349 Mus musculus 96.72 0.00e+00 1635.00
IUUC-Mpu-065824 Mustela putorius furo 97.45 0.00e+00 1630.00
IUUC-Mlu-067729 Myotis lucifugus 97.33 0.00e+00 1607.00
IUUC-Nle-069721 Nomascus leucogenys 98.78 0.00e+00 1647.00
IUUC-Opr-070189 Ochotona princeps 97.18 0.00e+00 1623.00
IUUC-Ont-072122 Oreochromis niloticus 80.68 0.00e+00 1368.00
IUUC-Oan-072700 Ornithorhynchus anatinus 84.30 0.00e+00 1232.00
IUUC-Ocu-074057 Oryctolagus cuniculus 97.45 0.00e+00 1638.00
IUUC-Ola-087492 Oryzias latipes 79.00 0.00e+00 1370.00
IUUC-Oga-088084 Otolemur garnettii 97.93 0.00e+00 1641.00
IUUC-Oar-090354 Ovis aries 97.05 0.00e+00 1613.00
IUUC-Ptr-091456 Pan troglodytes 99.27 0.00e+00 1665.00
IUUC-Pan-092596 Papio anubis 98.06 0.00e+00 1638.00
IUUC-Psi-092942 Pelodiscus sinensis 92.10 0.00e+00 1526.00
IUUC-Pma-094662 Petromyzon marinus 60.62 0.00e+00 751.00
IUUC-Pfo-096838 Poecilia formosa 80.44 0.00e+00 1350.00
IUUC-Pca-100498 Procavia capensis 95.19 0.00e+00 937.00
IUUC-Pva-102599 Pteropus vampyrus 97.45 0.00e+00 1620.00
IUUC-Rno-105776 Rattus norvegicus 97.21 0.00e+00 1625.00
IUUC-Sha-106699 Sarcophilus harrisii 94.17 0.00e+00 1538.00
IUUC-Sar-113621 Sorex araneus 95.57 0.00e+00 1583.00
IUUC-Ssc-115742 Sus scrofa 97.45 0.00e+00 1643.00
IUUC-Tgu-116490 Taeniopygia guttata 90.64 0.00e+00 1521.00
IUUC-Tru-117679 Takifugu rubripes 79.71 0.00e+00 1357.00
IUUC-Tsy-119607 Tarsius syrichta 93.56 0.00e+00 1139.00
IUUC-Tni-120376 Tetraodon nigroviridis 76.42 0.00e+00 1280.00
IUUC-Tbe-127348 Tupaia belangeri 67.52 0.00e+00 649.00
IUUC-Ttr-128786 Tursiops truncatus 93.80 0.00e+00 1569.00
IUUC-Vpa-130180 Vicugna pacos 96.84 0.00e+00 1304.00
IUUC-Xtr-132631 Xenopus tropicalis 67.87 0.00e+00 1143.00
Created Date 25-Jun-2017

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