iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000009368.3	ENSMMUT00000013088.3	ENSMMUP00000012267.3
ENSMMUG00000009368.3	ENSMMUT00000013089.3	ENSMMUP00000012268.3
ENSMMUG00000009368.3	ENSMMUT00000026926.2	ENSMMUP00000025190.2
ENSMMUG00000009368.3	ENSMMUT00000077391.1	ENSMMUP00000050416.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.90e-19	68.3	652	682
UBD/SH3	8.50e-14	52.4	1055	1107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH + +++l++  +d++++++s Dgt ++W 
   Q: 652  GHLNIIYDLSWskDDRYILTSSSDGTARIWK 682
           79999*******666***************7 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v +lydy+a+ +deLt+++Gd+++v      +e+W++g +  eg++G fP+n v+
   Q: 1055 TVVALYDYTANRSDELTIHRGDIIRVF--FRDNEDWWYG-SIGEGQEGYFPANHVA 1107
           689***********************9..8999******.79***********996 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MPTAESEAKV KTKVRFEELL KTHSDLTREK KKLKKKLVKS GENISPDTIR SNPHHIKETT 60
SDDPDTVRSN LPHIEETTSD DVSATNTNNL KKTMRVAKNK SRNTQSATEN PNDDVSVEED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAACGGCGG TGTAGGCAGG CGCTGACGTC AGCAGGCCGC GAGTAGTCCG CACTGCGGCA 60
CAGAGCAGTG GCTTGCTCTC CGAACCCGGG TCGCTGGCGG GTAAGGTGGC TTCGTGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001452--SH3_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50002--SH3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00018--SH3_1
PF00400--WD40

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00320--WD40

Gene Ontology

GO:0005912--C:adherens junction
GO:0005911--C:cell-cell junction
GO:0005814--C:centriole
GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0005929--C:cilium
GO:0097730--C:non-motile cilium
GO:0034613--P:cellular protein localization
GO:0007417--P:central nervous system development
GO:0060271--P:cilium assembly
GO:0035844--P:cloaca development
GO:0001947--P:heart looping
GO:0030902--P:hindbrain development
GO:0070121--P:Kupffer's vesicle development
GO:0070986--P:left/right axis specification
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0043066--P:negative regulation of apoptotic process
GO:0071599--P:otic vesicle development
GO:0035845--P:photoreceptor cell outer segment organization
GO:0030862--P:positive regulation of polarized epithelial cell differentiation
GO:0002092--P:positive regulation of receptor internalization
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0039023--P:pronephric duct morphogenesis
GO:0039008--P:pronephric nephron tubule morphogenesis
GO:0050795--P:regulation of behavior
GO:0010842--P:retina layer formation
GO:0065001--P:specification of axis polarity
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016192--P:vesicle-mediated transport

KEGG

mcc:706412

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001943	Ailuropoda melanoleuca	83.33	0.00e+00	1655.00
IUUC-Apl-004057	Anas platyrhynchos	50.60	0.00e+00	1062.00
IUUC-Aca-004306	Anolis carolinensis	46.83	0.00e+00	959.00
IUUC-Ame-010981	Astyanax mexicanus	49.20	0.00e+00	837.00
IUUC-Bta-013129	Bos taurus	82.71	0.00e+00	1824.00
IUUC-Cja-018979	Callithrix jacchus	88.72	0.00e+00	1761.00
IUUC-Cfa-020121	Canis familiaris	82.12	0.00e+00	1861.00
IUUC-Cpo-022219	Cavia porcellus	80.81	0.00e+00	1359.00
IUUC-Csa-023991	Chlorocebus sabaeus	97.84	0.00e+00	2246.00
IUUC-Cho-024782	Choloepus hoffmanni	78.30	0.00e+00	971.00
IUUC-Cin-025149	Ciona intestinalis	39.31	6.00e-168	584.00
IUUC-Csv-026188	Ciona savignyi	38.54	7.00e-123	434.00
IUUC-Dre-028737	Danio rerio	51.86	0.00e+00	858.00
IUUC-Dno-029756	Dasypus novemcinctus	81.32	0.00e+00	1767.00
IUUC-Dor-030821	Dipodomys ordii	69.75	0.00e+00	1501.00
IUUC-Ete-032237	Echinops telfairi	78.11	0.00e+00	1553.00
IUUC-Eca-033491	Equus caballus	81.16	0.00e+00	1872.00
IUUC-Eeu-034812	Erinaceus europaeus	73.10	0.00e+00	944.00
IUUC-Fca-035868	Felis catus	81.96	0.00e+00	1805.00
IUUC-Fal-037571	Ficedula albicollis	54.98	0.00e+00	785.00
IUUC-Gmo-039358	Gadus morhua	50.58	0.00e+00	791.00
IUUC-Gga-040233	Gallus gallus	54.64	0.00e+00	979.00
IUUC-Gac-041744	Gasterosteus aculeatus	48.89	0.00e+00	800.00
IUUC-Ggo-044766	Gorilla gorilla	93.68	0.00e+00	2197.00
IUUC-Hsa-046660	Homo sapiens	93.18	0.00e+00	2184.00
IUUC-Itr-048282	Ictidomys tridecemlineatus	84.86	0.00e+00	1930.00
IUUC-Loc-052658	Lepisosteus oculatus	49.37	0.00e+00	930.00
IUUC-Laf-053564	Loxodonta africana	85.86	0.00e+00	1456.00
IUUC-Meu-056362	Macropus eugenii	54.51	0.00e+00	879.00
IUUC-Mga-060033	Meleagris gallopavo	51.67	0.00e+00	1086.00
IUUC-Mmr-061075	Microcebus murinus	83.84	0.00e+00	1960.00
IUUC-Mdo-062818	Monodelphis domestica	54.75	0.00e+00	1174.00
IUUC-Mmu-063987	Mus musculus	78.01	0.00e+00	1599.00
IUUC-Mpu-066242	Mustela putorius furo	79.23	0.00e+00	1763.00
IUUC-Mlu-067123	Myotis lucifugus	77.41	0.00e+00	1687.00
IUUC-Nle-069793	Nomascus leucogenys	93.84	0.00e+00	2202.00
IUUC-Opr-071110	Ochotona princeps	75.52	0.00e+00	880.00
IUUC-Ont-072179	Oreochromis niloticus	49.01	0.00e+00	825.00
IUUC-Oan-073201	Ornithorhynchus anatinus	64.33	7.00e-136	476.00
IUUC-Ocu-074224	Oryctolagus cuniculus	83.76	0.00e+00	1977.00
IUUC-Ola-086818	Oryzias latipes	53.24	4.00e-73	267.00
IUUC-Oga-088338	Otolemur garnettii	86.80	0.00e+00	1825.00
IUUC-Oar-089247	Ovis aries	78.90	0.00e+00	1827.00
IUUC-Ptr-090830	Pan troglodytes	95.08	0.00e+00	2146.00
IUUC-Pan-092469	Papio anubis	97.67	0.00e+00	2294.00
IUUC-Psi-093183	Pelodiscus sinensis	51.18	0.00e+00	1053.00
IUUC-Pma-094415	Petromyzon marinus	47.75	4.00e-162	565.00
IUUC-Pfo-096577	Poecilia formosa	56.76	0.00e+00	756.00
IUUC-Pab-098236	Pongo abelii	94.69	0.00e+00	1893.00
IUUC-Pca-100560	Procavia capensis	66.14	0.00e+00	1437.00
IUUC-Pva-102565	Pteropus vampyrus	75.16	0.00e+00	1316.00
IUUC-Rno-104881	Rattus norvegicus	77.84	0.00e+00	1617.00
IUUC-Sha-106577	Sarcophilus harrisii	66.50	7.00e-165	573.00
IUUC-Sar-113265	Sorex araneus	70.37	0.00e+00	1508.00
IUUC-Ssc-116174	Sus scrofa	81.33	0.00e+00	1815.00
IUUC-Tgu-116618	Taeniopygia guttata	48.04	0.00e+00	880.00
IUUC-Tru-117761	Takifugu rubripes	42.70	0.00e+00	676.00
IUUC-Tsy-119557	Tarsius syrichta	81.31	0.00e+00	969.00
IUUC-Tni-119782	Tetraodon nigroviridis	50.45	0.00e+00	817.00
IUUC-Tbe-127529	Tupaia belangeri	71.16	4.00e-147	516.00
IUUC-Ttr-128444	Tursiops truncatus	77.14	0.00e+00	1767.00
IUUC-Vpa-130337	Vicugna pacos	72.57	0.00e+00	1588.00
IUUC-Xtr-132055	Xenopus tropicalis	57.14	0.00e+00	739.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence