• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
UUCD2 ID IUUC-Aml-001356
UUCD1 version UUC-AiM-01097
Ensembl Protein ID ENSAMEP00000011528.1
UniProt Accession D2GUD7; D2GUD7_AILME
Genbank Protein ID EFB29347.1
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID ACTA01000306
Gene Name USP13; PANDA_000244
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000010896.1 ENSAMET00000012020.1 ENSAMEP00000011528.1
ENSAMEG00000010896.1 ENSAMET00000012026.1 ENSAMEP00000011535.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 6.70e-57 193.3 333 857
UBD/Alpha-Helix/UBA 6.10e-20 70.8 727 764
Active Site
Position(s) Description Evidence
342 Nucleophile {ECO:0000256|PIRSR:PIRSR016308-1}
820 Proton acceptor {ECO:0000256|PIRSR:PIRSR016308-1}
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel......................wkskkka 67
           tGlkNlgN+CY+ Sv+Q++++ipe+++++  + ++ ++ + p +p++++ ++++kl + l                       k +++ 
   Q: 333  TGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYS-PLDPTQDFNTQMTKLGHGLlsgqyskppvkselieqvmkeeHKPQQNG 420
           7******************************788777765.79*****************8888888888888877765543388888* PP
   S: 68   vsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikc 156
           +spr++++ ++k ++efs+++qqDaqEf+ +l++ +e++                               +++  sd+F++ ++++i+c
   Q: 421  ISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNR-----------------------------IGSENPSDVFRFLVEERIQC 480
           *************************************998.............................688899************** PP
   S: 157  lecdnvssreepfldlslpvpgkeetkke...........................slqdcLesftkeeelegenkyycekckkkqeae 218
            + ++v  +e   + ++lpv ++  t+k                             ++ cL++f+++e++++   ++++  ++k+  +
   Q: 481  CQTRKVRYTERVDYLMQLPVAMEAATNKDeliayeltrreaeanrrplpelvrakiPFSACLQAFSEPENVDD---FWSSALQAKSAGV 566
           ******9999999999999999998887799****************************************97...************* PP
   S: 219  kklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts........................................ 267
           k+ ++ ++Pe+L++++k+f+f  + ++++k++ ++++p+ Ld+++  ++                                        
   Q: 567  KTSRFASFPEYLVVQIKKFTFGLD-WVPKKFDVSIDMPDLLDINHLRARglqpgeeelpdisppivipddskdrlmnqlidpseidess 654
           *********************997.*******************999889999999999999999998888888888888888888877 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 655  vmqlaemgfpleacrkavyftgnmgaevafnwiivhmeepdfaepltmpgyggaasagasvfgatgldnqppeeivaiitsmgfhrnqa 743
           77777777777777777777777777777777777777777777777777777777777777777776666666666666666666666 PP
   S: 268  ..........peekqke............................................kkkYeLiavvvHsG.slssGHYvayvkn 301
                           e                                            +  YeL+a ++H+G s+ sGHYv+++k+
   Q: 744  vqalratnnnL-----EraldwifshpefeedsdfviemennananiiseakpegprvkdgSGMYELFAFISHMGtSTMSGHYVCHIKK 827
           66665555550.....055555555555555555666666666677788888888888888**************************** PP
   S: 302  ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
            +g+W+ ++D++V ++  e+  +   + +Y++fY+r
   Q: 828  -EGRWVIYNDHRVCAS--ERPPK---DLGYMYFYHR 857
           .9***********999..78888...89******97 PP
   

   UBD/Alpha-Helix/UBA
   S: 4    edkleqlveMGFdreealqaLraannnleaAveyLldg 41
           e++++ +++MGF r++a+qaLra+nnnle+A+++++++
   Q: 727  EEIVAIITSMGFHRNQAVQALRATNNNLERALDWIFSH 764
           899*********************************97 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
RGALFGMPGG SGSRKMAAGD IGELLVPHMP TIRVPRSGDR VYKNECAFSY DSPNSEGGLY 60
VCMNTFLAFG REHVERHFRK TGQSVYMHLK RHVREKVRGA SGGALPKRRN SKIFLDLDTD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001356|DUB,USP;UBD,UBA|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGGGCGCCC TGTTCGGCAT GCCGGGCGGC AGCGGCAGCA GGAAGATGGC TGCAGGAGAC 60
ATCGGCGAGC TGCTGGTGCC TCACATGCCC ACGATCCGCG TGCCCAGGTC GGGGGACAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001356|DUB,USP;UBD,UBA|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP
SMART

SM00165--UBA
SM00290--ZnF_UBP
Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1904454--F:ubiquitin-specific protease activity involved in positive regulation of ERAD pathway
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:1904378--P:maintenance of unfolded protein involved in ERAD pathway
GO:0035523--P:protein K29-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050821--P:protein stabilization
GO:0010506--P:regulation of autophagy
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003712 Anas platyrhynchos 83.58 0.00e+00 1355.00
IUUC-Aca-004634 Anolis carolinensis 83.28 0.00e+00 1400.00
IUUC-Ame-011470 Astyanax mexicanus 74.62 0.00e+00 1285.00
IUUC-Bta-013349 Bos taurus 97.90 0.00e+00 1645.00
IUUC-Cja-019021 Callithrix jacchus 96.16 0.00e+00 1576.00
IUUC-Cfa-020614 Canis familiaris 99.07 0.00e+00 1624.00
IUUC-Cpo-022484 Cavia porcellus 97.79 0.00e+00 1504.00
IUUC-Csa-024078 Chlorocebus sabaeus 98.49 0.00e+00 1617.00
IUUC-Cho-024522 Choloepus hoffmanni 80.89 0.00e+00 1174.00
IUUC-Cme-027335 Cyanidioschyzon merolae 25.58 3.00e-53 204.00
IUUC-Dre-027651 Danio rerio 74.77 0.00e+00 1347.00
IUUC-Dno-028975 Dasypus novemcinctus 97.68 0.00e+00 1606.00
IUUC-Dor-030130 Dipodomys ordii 73.25 0.00e+00 1061.00
IUUC-Ete-032251 Echinops telfairi 82.13 0.00e+00 1274.00
IUUC-Eca-033568 Equus caballus 98.88 0.00e+00 1511.00
IUUC-Eeu-034612 Erinaceus europaeus 79.65 0.00e+00 1149.00
IUUC-Fca-036280 Felis catus 99.50 0.00e+00 1519.00
IUUC-Fal-036610 Ficedula albicollis 84.50 0.00e+00 1332.00
IUUC-Gmo-038906 Gadus morhua 72.46 0.00e+00 1248.00
IUUC-Gga-041215 Gallus gallus 83.31 0.00e+00 1430.00
IUUC-Gac-042441 Gasterosteus aculeatus 72.29 0.00e+00 1273.00
IUUC-Ggo-044446 Gorilla gorilla 98.25 0.00e+00 1615.00
IUUC-Hsa-046546 Homo sapiens 98.25 0.00e+00 1611.00
IUUC-Itr-048147 Ictidomys tridecemlineatus 89.42 0.00e+00 1428.00
IUUC-Lch-050425 Latimeria chalumnae 77.71 0.00e+00 1357.00
IUUC-Loc-052072 Lepisosteus oculatus 77.54 0.00e+00 1308.00
IUUC-Laf-053909 Loxodonta africana 96.06 0.00e+00 1593.00
IUUC-Mcc-054686 Macaca mulatta 98.49 0.00e+00 1617.00
IUUC-Meu-056361 Macropus eugenii 80.40 0.00e+00 1309.00
IUUC-Mga-059972 Meleagris gallopavo 79.09 0.00e+00 1296.00
IUUC-Mmr-060916 Microcebus murinus 97.32 0.00e+00 1602.00
IUUC-Mdo-062302 Monodelphis domestica 89.26 0.00e+00 1513.00
IUUC-Mmu-063639 Mus musculus 95.11 0.00e+00 1592.00
IUUC-Mpu-066533 Mustela putorius furo 99.65 0.00e+00 1630.00
IUUC-Mlu-067786 Myotis lucifugus 91.89 0.00e+00 1472.00
IUUC-Nle-069997 Nomascus leucogenys 98.12 0.00e+00 1488.00
IUUC-Ont-071859 Oreochromis niloticus 72.75 0.00e+00 1274.00
IUUC-Oan-072959 Ornithorhynchus anatinus 88.70 4.00e-129 453.00
IUUC-Ocu-074265 Oryctolagus cuniculus 97.67 0.00e+00 1594.00
IUUC-Ola-087344 Oryzias latipes 71.66 0.00e+00 1278.00
IUUC-Oga-088734 Otolemur garnettii 97.95 0.00e+00 1553.00
IUUC-Oar-089636 Ovis aries 97.77 0.00e+00 1570.00
IUUC-Ptr-090982 Pan troglodytes 98.25 0.00e+00 1615.00
IUUC-Pan-091991 Papio anubis 98.60 0.00e+00 1619.00
IUUC-Psi-093509 Pelodiscus sinensis 86.33 0.00e+00 1457.00
IUUC-Pfo-096029 Poecilia formosa 74.22 0.00e+00 1317.00
IUUC-Pab-098672 Pongo abelii 93.95 0.00e+00 1512.00
IUUC-Pca-100860 Procavia capensis 74.31 0.00e+00 1038.00
IUUC-Pva-102545 Pteropus vampyrus 90.45 0.00e+00 1470.00
IUUC-Rno-105210 Rattus norvegicus 94.30 0.00e+00 1570.00
IUUC-Sar-113733 Sorex araneus 96.04 0.00e+00 771.00
IUUC-Tgu-116591 Taeniopygia guttata 84.69 0.00e+00 1432.00
IUUC-Tru-118627 Takifugu rubripes 71.22 0.00e+00 1288.00
IUUC-Tsy-119278 Tarsius syrichta 89.21 0.00e+00 1347.00
IUUC-Tni-120804 Tetraodon nigroviridis 74.05 0.00e+00 1317.00
IUUC-Tbe-127699 Tupaia belangeri 79.03 0.00e+00 874.00
IUUC-Ttr-128295 Tursiops truncatus 89.77 0.00e+00 1464.00
IUUC-Vpa-130170 Vicugna pacos 87.22 0.00e+00 1332.00
IUUC-Xtr-132809 Xenopus tropicalis 74.13 0.00e+00 1278.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved