iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037044

Ensembl Protein ID

ENSFALP00000002859.1

UniProt Accession

U3JJA5; U3JJA5_FICAL

Genbank Protein ID

ENSFALP00000002859

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011171

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000002721.1	ENSFALT00000002871.1	ENSFALP00000002859.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-32	109.5	1565	1601
UBD/Beta-Prp	1.30e-42	145.6	1432	1635

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H+d+v++laf ++ ++++s+++ g+ikvW+++t++++
   Q: 1565 HKDWVCALAFiPGrPMVLSACRGGVIKVWNVDTFTPV 1601
           ***********999*****************998775 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqclee... 131
            e +++++ ++p+g + + ++  + ++vw+ls  ++v +l+gh   v++l++++   + d +v+Gs+d +++v+++ +g++ +    
   Q: 1432 GEHQINQIALNPTG-TTLYAAAGNSVRVWELSRLQPVGKLSGHIGPVMCLTVNQtasNHDLVVTGSKDHYVKVFEITEGTVGNVgpt 1517
           46679********9.8999999********************************99777**********************988999 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
             ++ +h + + c+++++  ++l+sGs D+ ++ Wdl++++l+++   +h+d v  l+f + ++ ++s+ + g +k+w++ t + v 
   Q: 1518 hnFEPPHYDGIECLAIQG--DVLFSGSRDNGIKKWDLEQQELIQQIPNAHKDWVCALAFIPGRPMVLSACRGGVIKVWNVDTFTPVG 1602
           99999************9..9*************************999************************************** PP
   S: 217  tlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           + +gh+++++ + +   ++++ ++ssD  +++W++
   Q: 1603 EIKGHESPINAICTN--SKHIFTASSDCRVKLWNY 1635
           **********77777..****************96 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MDQRTGCAHI LRTRLVSPKA GLPSAFFSSR RIRPQLPKEK IEGCHICTSV TPGEPQVLLG 60
KDKAFTYDFV FDLDTWQERI YTTCMGKLIE GCFEGYNATV LAYGQTGAGK TYTMGTGFDM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACACTCTAG GACATGGATC AGAGGACGGG CTGTGCTCAC ATCCTCAGGA CCAGACTGGT 60
GTCCCCCAAG GCGGGGCTGC CCTCAGCCTT CTTCTCTTCC CGTAGGATCC GTCCGCAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	86.98	0.00e+00	2584.00
IUUC-Apl-003204	Anas platyrhynchos	79.62	0.00e+00	1665.00
IUUC-Aca-004506	Anolis carolinensis	81.72	0.00e+00	2454.00
IUUC-Ame-011515	Astyanax mexicanus	75.20	0.00e+00	1457.00
IUUC-Bta-013185	Bos taurus	71.25	0.00e+00	2023.00
IUUC-Cja-018844	Callithrix jacchus	85.11	0.00e+00	2581.00
IUUC-Cfa-021187	Canis familiaris	87.85	0.00e+00	2642.00
IUUC-Cpo-022444	Cavia porcellus	86.04	0.00e+00	2637.00
IUUC-Csa-023852	Chlorocebus sabaeus	87.97	0.00e+00	2654.00
IUUC-Cin-025160	Ciona intestinalis	43.43	2.00e-81	296.00
IUUC-Dre-027839	Danio rerio	73.92	0.00e+00	1417.00
IUUC-Dno-030058	Dasypus novemcinctus	83.84	0.00e+00	2558.00
IUUC-Dor-030673	Dipodomys ordii	83.97	0.00e+00	2462.00
IUUC-Ete-032705	Echinops telfairi	75.93	0.00e+00	804.00
IUUC-Eca-033885	Equus caballus	86.51	0.00e+00	2591.00
IUUC-Eeu-035338	Erinaceus europaeus	88.53	0.00e+00	1087.00
IUUC-Fca-035388	Felis catus	87.39	0.00e+00	2479.00
IUUC-Gmo-039034	Gadus morhua	67.29	0.00e+00	1253.00
IUUC-Gac-041328	Gasterosteus aculeatus	72.55	0.00e+00	2278.00
IUUC-Ggo-045392	Gorilla gorilla	87.29	0.00e+00	2631.00
IUUC-Hsa-046713	Homo sapiens	87.85	0.00e+00	2651.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	87.35	0.00e+00	1550.00
IUUC-Lch-049786	Latimeria chalumnae	80.28	0.00e+00	1589.00
IUUC-Loc-052703	Lepisosteus oculatus	79.74	0.00e+00	2452.00
IUUC-Laf-054193	Loxodonta africana	79.09	0.00e+00	2311.00
IUUC-Mcc-055484	Macaca mulatta	86.79	0.00e+00	2629.00
IUUC-Meu-056278	Macropus eugenii	82.73	0.00e+00	1170.00
IUUC-Mga-059816	Meleagris gallopavo	89.41	0.00e+00	2727.00
IUUC-Mmr-061071	Microcebus murinus	84.94	0.00e+00	2588.00
IUUC-Mdo-062845	Monodelphis domestica	87.27	0.00e+00	2670.00
IUUC-Mmu-063967	Mus musculus	86.94	0.00e+00	2592.00
IUUC-Mpu-066448	Mustela putorius furo	86.49	0.00e+00	2623.00
IUUC-Nle-070037	Nomascus leucogenys	85.92	0.00e+00	2043.00
IUUC-Opr-070325	Ochotona princeps	83.62	0.00e+00	2463.00
IUUC-Ont-071851	Oreochromis niloticus	73.91	0.00e+00	2279.00
IUUC-Oan-073615	Ornithorhynchus anatinus	84.49	0.00e+00	2460.00
IUUC-Ocu-073855	Oryctolagus cuniculus	87.25	0.00e+00	2605.00
IUUC-Ola-086703	Oryzias latipes	72.37	0.00e+00	2263.00
IUUC-Oga-088171	Otolemur garnettii	85.80	0.00e+00	2578.00
IUUC-Oar-089693	Ovis aries	75.58	0.00e+00	1146.00
IUUC-Ptr-090535	Pan troglodytes	85.88	0.00e+00	1672.00
IUUC-Pan-091917	Papio anubis	87.39	0.00e+00	2431.00
IUUC-Psi-093752	Pelodiscus sinensis	80.12	0.00e+00	1444.00
IUUC-Pfo-096827	Poecilia formosa	69.13	0.00e+00	1337.00
IUUC-Pab-098441	Pongo abelii	87.91	0.00e+00	2658.00
IUUC-Pca-100781	Procavia capensis	90.73	0.00e+00	866.00
IUUC-Pva-103099	Pteropus vampyrus	84.83	0.00e+00	1280.00
IUUC-Rno-105872	Rattus norvegicus	86.88	0.00e+00	2622.00
IUUC-Sha-107097	Sarcophilus harrisii	85.42	0.00e+00	2559.00
IUUC-Ssc-115638	Sus scrofa	87.67	0.00e+00	2321.00
IUUC-Tgu-116504	Taeniopygia guttata	93.38	0.00e+00	1835.00
IUUC-Tru-118242	Takifugu rubripes	73.40	0.00e+00	1483.00
IUUC-Ttr-128824	Tursiops truncatus	80.53	0.00e+00	2391.00
IUUC-Xtr-131798	Xenopus tropicalis	64.33	0.00e+00	1159.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence