iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090167

Ensembl Protein ID

ENSOARP00000021430.1

UniProt Accession

W5QFD2; W5QFD2_SHEEP

Genbank Protein ID

ENSOARP00000021430

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01004256

Gene Name

TRIM33

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000019960.1	ENSOART00000021730.1	ENSOARP00000021430.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.50e-09	36.9	888	933
E3 activity/RING/RING	3.70e-06	27.6	125	185

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C+vC++gg+    l++CekC ++fH +C+ ++   ++p+ + wiC+ Cr+
   Q: 888  DWCAVCQNGGD----LLCCEKCPKVFHLTCHVPT-LLSFPSGD-WICTFCRD 933
           79*********....*******************.*******7.******85 PP

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadCl...qkw........pglknssskefrCPlCr 46
           Ca+C++++    + +p++lpC H f++ Cl   ++          +   ++ + +rCP+Cr
   Q: 125  CAVCQQSLqsrrEAEPKLLPCLHSFCLRCLpepERQlnvpipggSNGDIQQVGVIRCPVCR 185
           ******999888556***************98844457788666555556667779****8 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAENKGGGEA ESGGGGSSSA PVTAGAAGLA AQEAEPPLAA VLVEEEEEEG GRAGAESGAA 60
GPDDGGVAAA SSGSAPAASA PAASMGPGVP GGAVSTPAPA PASAPAPGPS AGPPPGPPAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAAA ACAAAGGCGG CGGCGAGGCT GAGAGCGGCG GCGGGGGCAG CAGTAGCGCG 60
CCGGTAACTG CCGGAGCCGC CGGGCTCGCG GCGCAGGAGG CGGAGCCGCC TCTCGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR019786--Zinc_finger_PHD-type_CS
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD
SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0030514--P:negative regulation of BMP signaling pathway
GO:0016567--P:protein ubiquitination
GO:0017015--P:regulation of transforming growth factor beta receptor signaling pathway

KEGG

oas:101122480

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002364	Ailuropoda melanoleuca	97.33	0.00e+00	1737.00
IUUC-Apl-003894	Anas platyrhynchos	92.50	0.00e+00	1602.00
IUUC-Aca-004658	Anolis carolinensis	90.67	0.00e+00	1566.00
IUUC-Ath-006656	Arabidopsis thaliana	35.96	3.00e-12	68.20
IUUC-Ame-011619	Astyanax mexicanus	60.34	0.00e+00	1056.00
IUUC-Bta-013341	Bos taurus	98.51	0.00e+00	1715.00
IUUC-Cja-018733	Callithrix jacchus	97.91	0.00e+00	1758.00
IUUC-Cfa-020725	Canis familiaris	98.39	0.00e+00	1717.00
IUUC-Cpo-021833	Cavia porcellus	96.92	0.00e+00	1731.00
IUUC-Csa-023040	Chlorocebus sabaeus	98.21	0.00e+00	1708.00
IUUC-Cho-024934	Choloepus hoffmanni	95.69	0.00e+00	1627.00
IUUC-Cin-025200	Ciona intestinalis	31.46	9.00e-45	176.00
IUUC-Csv-026278	Ciona savignyi	47.25	4.00e-20	91.30
IUUC-Dre-027797	Danio rerio	72.93	8.00e-172	597.00
IUUC-Dno-028955	Dasypus novemcinctus	97.91	0.00e+00	1802.00
IUUC-Dme-032143	Drosophila melanogaster	31.98	3.00e-45	177.00
IUUC-Ete-032728	Echinops telfairi	95.31	0.00e+00	919.00
IUUC-Eca-033573	Equus caballus	97.42	0.00e+00	1715.00
IUUC-Eeu-035138	Erinaceus europaeus	85.71	0.00e+00	827.00
IUUC-Fca-035776	Felis catus	98.11	0.00e+00	1627.00
IUUC-Fal-037583	Ficedula albicollis	91.13	0.00e+00	1626.00
IUUC-Gmo-039353	Gadus morhua	61.73	0.00e+00	662.00
IUUC-Gga-040874	Gallus gallus	93.06	0.00e+00	1709.00
IUUC-Gac-041689	Gasterosteus aculeatus	55.93	0.00e+00	1106.00
IUUC-Ggo-045151	Gorilla gorilla	97.47	0.00e+00	1325.00
IUUC-Hsa-046169	Homo sapiens	98.21	0.00e+00	1707.00
IUUC-Itr-048377	Ictidomys tridecemlineatus	97.73	0.00e+00	751.00
IUUC-Lch-050411	Latimeria chalumnae	81.47	0.00e+00	1371.00
IUUC-Loc-051992	Lepisosteus oculatus	72.76	0.00e+00	1295.00
IUUC-Laf-054552	Loxodonta africana	97.59	0.00e+00	1642.00
IUUC-Mcc-055744	Macaca mulatta	98.11	0.00e+00	1704.00
IUUC-Meu-056647	Macropus eugenii	98.58	0.00e+00	704.00
IUUC-Mga-059589	Meleagris gallopavo	92.31	0.00e+00	962.00
IUUC-Mmr-060727	Microcebus murinus	98.41	0.00e+00	1739.00
IUUC-Mdo-063029	Monodelphis domestica	95.53	0.00e+00	1740.00
IUUC-Mmu-064033	Mus musculus	96.33	0.00e+00	1758.00
IUUC-Mpu-066679	Mustela putorius furo	97.91	0.00e+00	1733.00
IUUC-Mlu-067286	Myotis lucifugus	97.06	0.00e+00	1627.00
IUUC-Nle-069156	Nomascus leucogenys	97.91	0.00e+00	1699.00
IUUC-Opr-070309	Ochotona princeps	87.15	0.00e+00	1270.00
IUUC-Ont-071586	Oreochromis niloticus	55.50	0.00e+00	1048.00
IUUC-Oan-073205	Ornithorhynchus anatinus	94.50	0.00e+00	1454.00
IUUC-Ocu-074667	Oryctolagus cuniculus	95.01	0.00e+00	1611.00
IUUC-Olo-080499	Oryza longistaminata	47.17	4.00e-12	67.80
IUUC-Opu-083209	Oryza punctata	47.17	5.00e-12	67.40
IUUC-Ola-086481	Oryzias latipes	51.57	0.00e+00	947.00
IUUC-Oga-089101	Otolemur garnettii	97.42	0.00e+00	1726.00
IUUC-Ptr-090901	Pan troglodytes	98.31	0.00e+00	1708.00
IUUC-Pan-092448	Papio anubis	95.93	0.00e+00	1706.00
IUUC-Psi-093657	Pelodiscus sinensis	92.91	0.00e+00	1481.00
IUUC-Pma-094506	Petromyzon marinus	65.91	2.00e-50	190.00
IUUC-Pfo-097104	Poecilia formosa	68.66	3.00e-159	556.00
IUUC-Pab-097704	Pongo abelii	98.41	0.00e+00	1742.00
IUUC-Pca-101001	Procavia capensis	87.38	0.00e+00	646.00
IUUC-Pva-102733	Pteropus vampyrus	93.56	0.00e+00	1560.00
IUUC-Rno-105512	Rattus norvegicus	97.32	0.00e+00	1750.00
IUUC-Sha-107423	Sarcophilus harrisii	94.78	0.00e+00	1619.00
IUUC-Sar-113181	Sorex araneus	87.95	8.00e-145	508.00
IUUC-Ssc-116330	Sus scrofa	92.97	0.00e+00	1521.00
IUUC-Tgu-117388	Taeniopygia guttata	75.76	0.00e+00	1261.00
IUUC-Tru-118728	Takifugu rubripes	57.48	0.00e+00	983.00
IUUC-Tsy-119053	Tarsius syrichta	97.78	0.00e+00	1046.00
IUUC-Tni-120279	Tetraodon nigroviridis	47.06	9.00e-165	573.00
IUUC-Tbe-127573	Tupaia belangeri	88.97	0.00e+00	835.00
IUUC-Ttr-128594	Tursiops truncatus	99.01	0.00e+00	1750.00
IUUC-Vpa-130619	Vicugna pacos	92.99	0.00e+00	1100.00
IUUC-Xtr-132837	Xenopus tropicalis	85.02	0.00e+00	1503.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence