iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105265

Ensembl Protein ID

ENSRNOP00000025381.4

UniProt Accession

F1LQU9; F1LQU9_RAT

Genbank Protein ID

ENSRNOP00000025381

Protein Name

Small G protein-signaling modulator 3

Genbank Nucleotide ID

AABR07058522

Gene Name

Sgsm3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000018745.6	ENSRNOT00000025382.5	ENSRNOP00000025381.4

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.90e-10	40.3	496	551

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++ ++l d+e  +ddeL ++k d++++i   ++de  ++g  el+g rG fP+ Fve l+
   Q: 496  RRAKALLDFERHDDDELGFRKNDIITII--SQKDEHCWVG--ELNGLRGWFPAKFVEVLD 551
           56799***********************..777888888*..9**************987 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MPRSMKSCHR PQHMMSGNHT PSASGPFSAL TPSIWPQEIL AKSSQKEDSS EPEICYDEFG 60
FRVDKEGSEP GCSQMAGTPL VEDPPQRLRW QAHLEFTHNH DVGDLTWDKI AVSLPRSEKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGGAGCCAG CCGCTAGCCG GAGCAGCTGA GGTGCTGAGG TGGCCCTGAC ACAGGTGAGC 60
CGGGCGCGAG TCTCCGAGCG AGGCGAACGC TCACTAGCCC CTTAGTTGGA GGCCGCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000195--Rab-GTPase-TBC_dom
IPR004012--Run_dom
IPR001452--SH3_domain

PROSITE

PS50826--RUN
PS50002--SH3
PS50086--TBC_RABGAP

Pfam

PF00566--RabGAP-TBC
PF02759--RUN
PF00018--SH3_1

SMART

SM00593--RUN
SM00326--SH3
SM00164--TBC

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:0048227--P:plasma membrane to endosome transport
GO:0032486--P:Rap protein signal transduction
GO:0032483--P:regulation of Rab protein signal transduction

KEGG

rno:362963

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004863	Anolis carolinensis	86.57	0.00e+00	1301.00
IUUC-Cja-019526	Callithrix jacchus	93.04	0.00e+00	889.00
IUUC-Cfa-021075	Canis familiaris	94.94	0.00e+00	1390.00
IUUC-Dno-029715	Dasypus novemcinctus	91.55	0.00e+00	1361.00
IUUC-Dme-031891	Drosophila melanogaster	64.54	0.00e+00	991.00
IUUC-Eca-033476	Equus caballus	95.06	0.00e+00	1387.00
IUUC-Fca-035397	Felis catus	97.24	0.00e+00	828.00
IUUC-Laf-054163	Loxodonta africana	72.82	0.00e+00	1007.00
IUUC-Mcc-055074	Macaca mulatta	97.32	2.00e-152	531.00
IUUC-Mmu-063863	Mus musculus	98.53	0.00e+00	1441.00
IUUC-Mpu-065920	Mustela putorius furo	94.26	0.00e+00	1381.00
IUUC-Psi-093779	Pelodiscus sinensis	87.38	0.00e+00	1314.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence