iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067673

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02060326

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000003187.1	ENSMLUT00000003183.1	ENSMLUP00000002896.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	96.02	6.00e-115	410.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANVLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCACCC ACAGCAAGTT TCCCGCCGCC GGGATGAGCC GCCCCCTGGA CACCAGCCTG 60
CGCCTCAAGA CCTTCAGCTC CAAGAGCGAG TACCAGCTGG TGGTGAACGC CGTGCGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	85.84	4.00e-105	373.00
IUUC-Apl-003607	Anas platyrhynchos	80.53	2.00e-94	337.00
IUUC-Aca-005063	Anolis carolinensis	79.91	2.00e-102	364.00
IUUC-Ath-006990	Arabidopsis thaliana	32.94	1.60e-02	35.00
IUUC-Ame-010859	Astyanax mexicanus	55.41	8.00e-69	253.00
IUUC-Bta-012817	Bos taurus	90.39	2.00e-108	384.00
IUUC-Bra-017963	Brassica rapa	28.57	2.00e-01	30.80
IUUC-Cja-019605	Callithrix jacchus	89.82	2.00e-111	394.00
IUUC-Cfa-021231	Canis familiaris	87.17	9.00e-107	379.00
IUUC-Cpo-022003	Cavia porcellus	89.91	2.00e-106	378.00
IUUC-Csa-023511	Chlorocebus sabaeus	90.27	1.00e-109	389.00
IUUC-Dre-028536	Danio rerio	57.08	2.00e-71	261.00
IUUC-Dno-029003	Dasypus novemcinctus	88.50	1.00e-106	378.00
IUUC-Eca-034205	Equus caballus	76.54	3.00e-67	247.00
IUUC-Fca-036317	Felis catus	86.61	3.00e-105	374.00
IUUC-Gmo-038777	Gadus morhua	63.89	5.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	81.86	1.00e-95	342.00
IUUC-Gac-041837	Gasterosteus aculeatus	55.65	1.00e-64	238.00
IUUC-Ggo-045620	Gorilla gorilla	90.27	1.00e-109	389.00
IUUC-Hsa-046909	Homo sapiens	90.27	1.00e-109	389.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	87.18	6.00e-111	392.00
IUUC-Lch-049510	Latimeria chalumnae	66.09	8.00e-83	299.00
IUUC-Lpe-051525	Leersia perrieri	39.29	3.90e-01	29.30
IUUC-Loc-052863	Lepisosteus oculatus	62.77	7.00e-78	282.00
IUUC-Laf-054136	Loxodonta africana	90.79	4.00e-108	383.00
IUUC-Mcc-055383	Macaca mulatta	90.27	1.00e-109	389.00
IUUC-Meu-056153	Macropus eugenii	86.28	5.00e-110	389.00
IUUC-Mmr-061185	Microcebus murinus	93.81	2.00e-107	381.00
IUUC-Mdo-061819	Monodelphis domestica	86.28	4.00e-109	386.00
IUUC-Mmu-064231	Mus musculus	94.69	7.00e-117	412.00
IUUC-Mpu-066691	Mustela putorius furo	87.17	9.00e-107	379.00
IUUC-Ont-072406	Oreochromis niloticus	55.22	2.00e-68	251.00
IUUC-Oan-073249	Ornithorhynchus anatinus	75.22	1.00e-92	332.00
IUUC-Ocu-074935	Oryctolagus cuniculus	84.06	6.00e-31	124.00
IUUC-Ola-087373	Oryzias latipes	46.63	4.00e-48	184.00
IUUC-Oga-088041	Otolemur garnettii	89.82	2.00e-107	381.00
IUUC-Oar-089646	Ovis aries	88.65	2.00e-102	364.00
IUUC-Ptr-091502	Pan troglodytes	90.27	1.00e-109	389.00
IUUC-Pan-091934	Papio anubis	90.27	1.00e-109	389.00
IUUC-Pfo-096412	Poecilia formosa	41.74	2.00e-47	182.00
IUUC-Pab-098554	Pongo abelii	90.27	1.00e-109	389.00
IUUC-Rno-105874	Rattus norvegicus	94.69	7.00e-116	409.00
IUUC-Sha-107151	Sarcophilus harrisii	84.65	1.00e-108	385.00
IUUC-Ssc-115722	Sus scrofa	76.30	5.00e-64	236.00
IUUC-Tgu-117151	Taeniopygia guttata	81.14	2.00e-94	337.00
IUUC-Tru-118428	Takifugu rubripes	55.22	4.00e-68	250.00
IUUC-Tni-120590	Tetraodon nigroviridis	54.78	8.00e-67	246.00
IUUC-Ttr-129065	Tursiops truncatus	90.39	3.00e-109	387.00
IUUC-Xtr-132167	Xenopus tropicalis	65.04	2.00e-80	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence