iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044716

UUCD1 version

UUC-GoG-00629

Ensembl Protein ID

ENSGGOP00000015894.2

UniProt Accession

G3RJK2; G3RJK2_GORGO

Protein Name

Uncharacterized protein

Gene Name

SPOP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000009295.2	ENSGGOT00000016347.2	ENSGGOP00000015894.2
ENSGGOG00000009295.2	ENSGGOT00000009333.2	ENSGGOP00000009080.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.30e-33	113.0	205	271
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.20e-09	35.1	304	334

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D++l+v+g+ef+ahk++Laa+S+vF+a+f++e+eesk k++vei+dv+pevf+++++F+Ytgk+++ 
   Q: 205  TDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESK-KNRVEINDVEPEVFKEMMCFIYTGKAPNL 271
           7*************************************.*************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           +eN+++il +Adl+++++Lk +a+dfi++h 
   Q: 304  VENAAEILILADLHSADQLKTQAVDFINYHA 334
           79***************************95 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSRVPSPPPP AEMSSGPVAE SWCYTQQIKV VKFSYMWTIN NFSFCREEMG EVIKSSTFSS 60
GANDKLKWCL LLNKKGDLFA YLDPASQCYI LCILLLSVER DNIVARLEFF VLNLRQNKVN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAAGGG TTCCAAGTCC TCCACCTCCG GCAGAAATGT CGAGTGGCCC CGTAGCTGAG 60
AGTTGGTGCT ACACACAGGT AAGTTGAAGT TTTCAGCCTG TGAATCTTGC ATCTGGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR002083--MATH/TRAF_dom
IPR011333--SKP1/BTB/POZ
IPR034089--SPOP_C
IPR008974--TRAF-like

PROSITE

PS50097--BTB
PS50144--MATH

Pfam

PF00651--BTB

SMART

SM00225--BTB

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016607--C:nuclear speck
GO:0042593--P:glucose homeostasis
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:1902237--P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:2000676--P:positive regulation of type B pancreatic cell apoptotic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aor-009945	Aspergillus oryzae	38.46	2.00e-04	37.40
IUUC-Bgr-012157	Blumeria graminis	35.00	1.00e-04	40.40
IUUC-Cgl-026729	Colletotrichum gloeosporioides	30.30	1.00e-05	43.90
IUUC-Dno-029006	Dasypus novemcinctus	79.64	4.00e-162	563.00
IUUC-Lma-053106	Leptosphaeria maculans	23.53	2.00e-08	52.00
IUUC-Mor-057237	Magnaporthe oryzae	29.21	9.00e-08	50.40
IUUC-Mpo-057466	Magnaporthe poae	28.36	6.00e-08	50.80
IUUC-Oin-080027	Oryza indica	30.05	7.00e-30	124.00
IUUC-Oni-082475	Oryza nivara	30.05	1.00e-29	124.00
IUUC-Pva-102296	Pteropus vampyrus	79.74	1.00e-159	555.00
IUUC-Pyt-104526	Pyrenophora triticirepentis	23.53	9.00e-07	47.40
IUUC-Sja-107711	Schizosaccharomyces japonicus	28.33	4.00e-03	35.00
IUUC-Ssl-108548	Sclerotinia sclerotiorum	28.77	1.00e-06	47.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence