iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068037

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02030845

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000014025.2	ENSMLUT00000014038.2	ENSMLUP00000012769.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.80e-214	712.6	443	935

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+Gv      g++t++D d +e+snlnrqFLfr+++++k+K+ +aa+a  +
   Q: 443  YDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVgtskekGMVTITDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLK 531
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+v+++ah +++++ +e i+   F++k d++++aldn+earr+v+++ +++ +pl++sgt+G++G+++vi+++lte+ys+++dpp++
   Q: 532  INPQVKIDAHLNKVCPATEAIYsdeFYNKQDIIITALDNVEARRYVDSRSVANLRPLLDSGTMGTKGHTEVIVPHLTESYSSHRDPPEE 620
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl+kl++ +++eg ++v  +l s++++n+++++e+a+ +f+
   Q: 621  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYSSAEEVLQKLQTGHSLEGSFQV-IKLLSRRPRNWSQCVELARLKFE 708
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv............................................................s 275
           k++++++ qll++f+ d + k++s fw+                                                            +
   Q: 709  KYFNHKALQLLHCFPLDTRLKDGSLFWQspkrppcpikfdfneplhfsfllnaaklyatiycipfteekkqdistgallnilsevkiqE 797
           ***************************************************************99999999999999999999998885 PP
   S: 276  fcsnaealqvp.....ekvekdeevvkasap..lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldd 355
           f++ ++   ++     + v ++ + ++++ +  ++l++   ++ ++++++++++lsfekddd   ++d++taa+nlra++++iep +d+
   Q: 798  FKPSSKVRPQDfmvrgPDVPQPYISSEDERNaiFQLEKIMSSNEATTSDLQMAVLSFEKDDDRngHIDFITAASNLRAKMYSIEP-ADR 885
           555554444333333333333333333333356999999999*******************************************.*** PP
   S: 356  dlikeiagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           +++k+iag+iipaiatt+a+v+Gl+a+E+iKv+ g +fe++kn+fl++a+
   Q: 886  FKTKRIAGKIIPAIATTTAAVSGLVALEMIKVAAGyPFEAYKNCFLNLAI 935
           **********************************************9886 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MEGSEPVAAP RGEQASCSSW GAASTNTHLP MMSTESVEID DALYSRQRYV LGDTAMQKMA 60
KSHIFLSGMG GLGLEIAKNL VLAGIKALTI HDVKKCHAWD LGTNFFLCED DVVNMRNRAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGGAT CCGAGCCTGT GGCCGCACCT CGCGGGGAAC AGGCGTCCTG CTCTTCCTGG 60
GGTGCCGCCA GGTGAGAGCA CCCGTGTGGG CGCAGAAAGG CGAGGGGTGG CGGGCAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	91.21	0.00e+00	2003.00
IUUC-Apl-004158	Anas platyrhynchos	79.27	0.00e+00	1696.00
IUUC-Aca-005349	Anolis carolinensis	79.53	0.00e+00	1736.00
IUUC-Bta-012696	Bos taurus	90.44	0.00e+00	1989.00
IUUC-Cja-019563	Callithrix jacchus	89.98	0.00e+00	1951.00
IUUC-Cfa-020951	Canis familiaris	90.64	0.00e+00	1995.00
IUUC-Cpo-022307	Cavia porcellus	85.32	0.00e+00	1861.00
IUUC-Csa-023647	Chlorocebus sabaeus	90.17	0.00e+00	1966.00
IUUC-Cho-024682	Choloepus hoffmanni	75.72	0.00e+00	920.00
IUUC-Dre-028022	Danio rerio	65.79	0.00e+00	1444.00
IUUC-Dno-029796	Dasypus novemcinctus	88.88	0.00e+00	1895.00
IUUC-Dor-030981	Dipodomys ordii	74.33	0.00e+00	1484.00
IUUC-Ete-032514	Echinops telfairi	77.20	0.00e+00	1125.00
IUUC-Eca-033697	Equus caballus	91.50	0.00e+00	1969.00
IUUC-Eeu-035323	Erinaceus europaeus	84.28	0.00e+00	1372.00
IUUC-Fca-035858	Felis catus	91.59	0.00e+00	1975.00
IUUC-Fal-036848	Ficedula albicollis	79.45	0.00e+00	1699.00
IUUC-Gmo-039326	Gadus morhua	65.66	0.00e+00	1369.00
IUUC-Gga-040747	Gallus gallus	79.55	0.00e+00	1684.00
IUUC-Gac-041406	Gasterosteus aculeatus	65.18	0.00e+00	1351.00
IUUC-Ggo-044577	Gorilla gorilla	89.99	0.00e+00	1969.00
IUUC-Hsa-046007	Homo sapiens	90.17	0.00e+00	1963.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	90.19	0.00e+00	1008.00
IUUC-Lch-049992	Latimeria chalumnae	71.97	0.00e+00	1514.00
IUUC-Loc-051899	Lepisosteus oculatus	67.80	0.00e+00	1474.00
IUUC-Laf-054413	Loxodonta africana	89.40	0.00e+00	1824.00
IUUC-Mcc-054656	Macaca mulatta	90.26	0.00e+00	1967.00
IUUC-Meu-056463	Macropus eugenii	70.04	0.00e+00	1372.00
IUUC-Mga-059721	Meleagris gallopavo	77.27	0.00e+00	1587.00
IUUC-Mmr-060908	Microcebus murinus	86.67	0.00e+00	1904.00
IUUC-Mdo-062096	Monodelphis domestica	82.97	0.00e+00	1846.00
IUUC-Mmu-064114	Mus musculus	86.67	0.00e+00	1894.00
IUUC-Mpu-066017	Mustela putorius furo	90.93	0.00e+00	2002.00
IUUC-Nle-069494	Nomascus leucogenys	89.70	0.00e+00	1956.00
IUUC-Opr-070910	Ochotona princeps	65.80	5.00e-168	585.00
IUUC-Ont-071592	Oreochromis niloticus	66.89	0.00e+00	1410.00
IUUC-Oan-073268	Ornithorhynchus anatinus	78.48	0.00e+00	1550.00
IUUC-Ocu-074296	Oryctolagus cuniculus	89.70	0.00e+00	1962.00
IUUC-Ola-086376	Oryzias latipes	67.19	0.00e+00	1372.00
IUUC-Oga-088186	Otolemur garnettii	88.75	0.00e+00	1936.00
IUUC-Oar-089307	Ovis aries	90.64	0.00e+00	1988.00
IUUC-Ptr-090609	Pan troglodytes	90.08	0.00e+00	1958.00
IUUC-Pan-092905	Papio anubis	89.85	0.00e+00	1871.00
IUUC-Psi-093489	Pelodiscus sinensis	79.94	0.00e+00	1710.00
IUUC-Pma-094203	Petromyzon marinus	67.57	2.00e-58	217.00
IUUC-Pfo-096670	Poecilia formosa	67.02	0.00e+00	1420.00
IUUC-Pab-098418	Pongo abelii	90.26	0.00e+00	1962.00
IUUC-Pca-100889	Procavia capensis	72.94	0.00e+00	1536.00
IUUC-Pva-103144	Pteropus vampyrus	80.15	0.00e+00	1724.00
IUUC-Rno-105612	Rattus norvegicus	86.48	0.00e+00	1892.00
IUUC-Sha-107388	Sarcophilus harrisii	84.74	0.00e+00	1825.00
IUUC-Sar-113128	Sorex araneus	87.80	0.00e+00	1897.00
IUUC-Ssc-116117	Sus scrofa	91.03	0.00e+00	2007.00
IUUC-Tgu-116565	Taeniopygia guttata	79.57	0.00e+00	1705.00
IUUC-Tru-118591	Takifugu rubripes	65.69	0.00e+00	1379.00
IUUC-Tsy-119436	Tarsius syrichta	78.54	0.00e+00	1673.00
IUUC-Tni-120880	Tetraodon nigroviridis	65.18	0.00e+00	1368.00
IUUC-Tbe-127714	Tupaia belangeri	77.71	0.00e+00	1366.00
IUUC-Ttr-129159	Tursiops truncatus	78.73	0.00e+00	1661.00
IUUC-Vpa-130716	Vicugna pacos	88.06	0.00e+00	1843.00
IUUC-Xtr-132947	Xenopus tropicalis	68.64	0.00e+00	1486.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence