iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053537

Ensembl Protein ID

ENSLAFP00000015589.3

UniProt Accession

G3TL47; G3TL47_LOXAF

Protein Name

Uncharacterized protein

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000018594.3	ENSLAFT00000018596.3	ENSLAFP00000015589.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-29	101.2	705	742
UBD/Beta-Prp	5.20e-46	157.5	563	777

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H + vt+la  ++  +l sGs+D++i++W+l + ++++
   Q: 705  HLEAVTSLAVdPNgLYLMSGSHDCSIRLWNLESKTCIQ 742
           8899*******77799***************9999987 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvw.dlstgkcvhtlk.....ghedsvlslsfspsgdklvsGshdrtirvwdletgqc 128
             l gh+++v+ + +s   + l+++s D+t+++w   ++ + +++++     g  +sv ++s++p  +++v+  +  +  ++++et+q 
   Q: 563  GPLVGHTDAVWGLAYSAAHQRLLSCSADGTLRLWgTAEAAPALSVFNdnqdlGIPASVDLVSSDP--SHMVASFSKGYTSIFNMETQQR 649
           4589******************************8888999999999666777777777788888..888888889************* PP
   S: 129  lee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           + +      t + ++  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l++
   Q: 650  ILTlesnldTTASTSCQINRVISHPTLPISITAHEDRHIKFFDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLES 737
           **99999998888888999999***99**************************98.********************************* PP
   S: 212  gecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 738  KTCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 777
           ***********999999******************97655 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MDEQAGPGVF FSNNHPGAGG AKGLGPLAEA AVAGDGAAAA GAARAQYSLP GILHFLQHEW 60
ARFEVERAQW EVERAELQAQ IAFLQGERKG QENLKKDLVR RIKMLEYALK QERAKYHKLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAGC AGGCGGGTCC TGGCGTCTTC TTCAGCAACA ACCACCCGGG CGCCGGTGGT 60
GCCAAGGGGC TCGGGCCTCT GGCGGAGGCT GCCGTGGCCG GCGACGGGGC GGCCGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

KEGG

lav:100677092

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	97.01	0.00e+00	1372.00
IUUC-Apl-003927	Anas platyrhynchos	88.23	0.00e+00	1126.00
IUUC-Aca-004933	Anolis carolinensis	80.76	0.00e+00	1153.00
IUUC-Ate-010457	Aspergillus terreus	26.24	1.00e-30	128.00
IUUC-Ame-010997	Astyanax mexicanus	73.53	0.00e+00	1076.00
IUUC-Bta-013077	Bos taurus	96.67	0.00e+00	1378.00
IUUC-Cja-018973	Callithrix jacchus	97.44	0.00e+00	1385.00
IUUC-Cfa-020988	Canis familiaris	93.46	0.00e+00	1243.00
IUUC-Cpo-022496	Cavia porcellus	96.28	0.00e+00	1382.00
IUUC-Csa-023829	Chlorocebus sabaeus	96.29	0.00e+00	1372.00
IUUC-Dre-028560	Danio rerio	69.22	0.00e+00	977.00
IUUC-Dno-029742	Dasypus novemcinctus	91.54	0.00e+00	1313.00
IUUC-Dor-030721	Dipodomys ordii	88.33	0.00e+00	1252.00
IUUC-Eca-033760	Equus caballus	97.01	0.00e+00	1281.00
IUUC-Eeu-034953	Erinaceus europaeus	95.83	0.00e+00	745.00
IUUC-Fca-036530	Felis catus	97.30	0.00e+00	1311.00
IUUC-Fal-037353	Ficedula albicollis	81.82	0.00e+00	896.00
IUUC-Gga-040132	Gallus gallus	88.30	0.00e+00	1143.00
IUUC-Gac-041713	Gasterosteus aculeatus	73.58	0.00e+00	1061.00
IUUC-Ggo-045455	Gorilla gorilla	84.95	0.00e+00	1176.00
IUUC-Hsa-046415	Homo sapiens	96.79	0.00e+00	1377.00
IUUC-Lch-050475	Latimeria chalumnae	81.14	0.00e+00	1199.00
IUUC-Loc-051859	Lepisosteus oculatus	77.72	0.00e+00	1149.00
IUUC-Mcc-055817	Macaca mulatta	96.05	0.00e+00	1371.00
IUUC-Meu-055946	Macropus eugenii	69.65	0.00e+00	904.00
IUUC-Mor-057148	Magnaporthe oryzae	45.07	8.00e-18	85.90
IUUC-Mga-059694	Meleagris gallopavo	88.35	0.00e+00	1120.00
IUUC-Mmr-060768	Microcebus murinus	97.56	0.00e+00	1409.00
IUUC-Mdo-061901	Monodelphis domestica	86.80	0.00e+00	1311.00
IUUC-Mmu-064154	Mus musculus	95.26	0.00e+00	1360.00
IUUC-Mpu-065827	Mustela putorius furo	91.97	0.00e+00	1380.00
IUUC-Mlu-067102	Myotis lucifugus	96.46	0.00e+00	1345.00
IUUC-Ncr-068831	Neurospora crassa	40.59	2.00e-22	100.00
IUUC-Nle-070008	Nomascus leucogenys	96.73	0.00e+00	1284.00
IUUC-Opr-071067	Ochotona princeps	60.84	1.00e-177	615.00
IUUC-Ont-072025	Oreochromis niloticus	73.42	0.00e+00	1060.00
IUUC-Oan-072950	Ornithorhynchus anatinus	91.77	0.00e+00	1169.00
IUUC-Ocu-074316	Oryctolagus cuniculus	96.16	0.00e+00	1267.00
IUUC-Ola-087279	Oryzias latipes	71.70	0.00e+00	1033.00
IUUC-Oga-088284	Otolemur garnettii	96.92	0.00e+00	1399.00
IUUC-Oar-090304	Ovis aries	97.18	0.00e+00	1383.00
IUUC-Ptr-091052	Pan troglodytes	96.92	0.00e+00	1379.00
IUUC-Pan-092270	Papio anubis	90.92	0.00e+00	1330.00
IUUC-Psi-093907	Pelodiscus sinensis	88.33	0.00e+00	1045.00
IUUC-Pfo-097042	Poecilia formosa	72.82	0.00e+00	1148.00
IUUC-Pab-098110	Pongo abelii	96.92	0.00e+00	1379.00
IUUC-Pca-100266	Procavia capensis	85.67	0.00e+00	998.00
IUUC-Pva-102824	Pteropus vampyrus	94.62	0.00e+00	1352.00
IUUC-Rno-105638	Rattus norvegicus	95.64	0.00e+00	1368.00
IUUC-Sha-107004	Sarcophilus harrisii	87.98	0.00e+00	1122.00
IUUC-Sre-115115	Sporisorium reilianum	34.11	1.00e-64	241.00
IUUC-Ssc-115280	Sus scrofa	97.18	0.00e+00	1390.00
IUUC-Tgu-116759	Taeniopygia guttata	88.49	0.00e+00	1146.00
IUUC-Tru-117944	Takifugu rubripes	73.16	0.00e+00	1056.00
IUUC-Tsy-119405	Tarsius syrichta	85.90	0.00e+00	1079.00
IUUC-Tni-120571	Tetraodon nigroviridis	72.98	0.00e+00	1068.00
IUUC-Tme-126990	Tuber melanosporum	26.39	6.00e-36	145.00
IUUC-Uma-129659	Ustilago maydis	34.96	8.00e-65	242.00
IUUC-Vpa-130294	Vicugna pacos	96.15	0.00e+00	1268.00
IUUC-Xma-134233	Xiphophorus maculatus	68.54	0.00e+00	910.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence