iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097614

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01113920

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000003722.2	ENSPPYT00000004425.2	ENSPPYP00000004252.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.90e-82	275.9	442	926

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf  l +s++ a+sp+++l+a +   + fs   qq
   Q: 442  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFGFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 519
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++s + +e++   +++ ++++F+g++ ++i cl c nvssree f+dlsl++p  
   Q: 520  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSSPSPPEEPLAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPP 603
           *****************.....67888888888999999999*********************************************99 PP
   S: 180  eetkke................................................................................... 185
           e +  +                                                                                   
   Q: 604  ERCRRRrlgsvmrpteditarelppptsaqgpgrvgprrqrkhcitgdtlptnlyiegldskeaggqssreekvereeerkeertekee 692
           98877799********************************************************************************* PP
   S: 186  ...................................................................slqdcLesftkeeelegenkyy 207
                                                                              s+ d+ + f ++e+l+ en+yy
   Q: 693  vgeeeestrgeeerekeeeveeeeekveketekeaqqekeedslgvgthldaaipsgeqtcgsegsrSVLDLVNYFLSPEKLTAENRYY 781
           ***************************************************************************************** PP
   S: 208  cekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHY 295
           ce+c ++q+aek ++l++ P++Lil L Rfsf+ ++++r+ki + v++pl L l     +        + Y+L++vvvHsG s++sGHY
   Q: 782  CESCASLQDAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGGR-------GQAYDLCSVVVHSGvSSESGHY 863
           *************************************************99999855555.......89******************** PP
   S: 296  vayvkn................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
           ++y+++                 +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 864  YCYAREgaarpapslgtadrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 926
           ******99999999999999888999*******************999************985 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MDKILEAVVT SSYPVSVKQG LVRRVLEAAR QPLEREQCLA LLALGARLYV GGAEELPRRV 60
GCQLLHVAGR HHPDVFAEFF SARRVLRLLQ GGAGPPGPRA LACVQLGLQL LPEGPAADEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCTTGGAGGC GGTGGTGACG TCGTCATACC CGGTGAGCGT GAAGCAGGGG 60
CTTGTTCGGC GCGTGCTGGA GGCGGCGAGG CAGCCGCTGG AGCGTGAGCA GTGCCTGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	87.59	0.00e+00	961.00
IUUC-Apl-004121	Anas platyrhynchos	67.26	0.00e+00	887.00
IUUC-Bta-012545	Bos taurus	91.48	0.00e+00	1145.00
IUUC-Cja-019731	Callithrix jacchus	96.88	0.00e+00	1197.00
IUUC-Cfa-020095	Canis familiaris	93.90	0.00e+00	1165.00
IUUC-Cpo-021961	Cavia porcellus	92.92	0.00e+00	1152.00
IUUC-Csa-023167	Chlorocebus sabaeus	97.62	0.00e+00	1180.00
IUUC-Dno-029186	Dasypus novemcinctus	82.96	0.00e+00	829.00
IUUC-Dor-030538	Dipodomys ordii	97.18	0.00e+00	972.00
IUUC-Ete-032512	Echinops telfairi	89.33	3.00e-105	375.00
IUUC-Eca-033279	Equus caballus	95.92	0.00e+00	902.00
IUUC-Eeu-035120	Erinaceus europaeus	71.94	0.00e+00	824.00
IUUC-Fca-035969	Felis catus	92.05	0.00e+00	885.00
IUUC-Fal-037625	Ficedula albicollis	67.51	0.00e+00	893.00
IUUC-Gga-040767	Gallus gallus	67.01	0.00e+00	891.00
IUUC-Ggo-045323	Gorilla gorilla	98.16	0.00e+00	1387.00
IUUC-Hsa-046124	Homo sapiens	98.65	0.00e+00	1193.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	93.43	0.00e+00	1136.00
IUUC-Laf-053999	Loxodonta africana	88.43	0.00e+00	1131.00
IUUC-Mcc-055266	Macaca mulatta	96.74	0.00e+00	1162.00
IUUC-Meu-056906	Macropus eugenii	74.63	0.00e+00	981.00
IUUC-Mga-059595	Meleagris gallopavo	70.63	0.00e+00	871.00
IUUC-Mmr-061720	Microcebus murinus	92.79	0.00e+00	709.00
IUUC-Mdo-062167	Monodelphis domestica	74.55	0.00e+00	978.00
IUUC-Mmu-063298	Mus musculus	91.65	0.00e+00	1142.00
IUUC-Mpu-066195	Mustela putorius furo	93.29	0.00e+00	1147.00
IUUC-Mlu-067583	Myotis lucifugus	87.61	0.00e+00	775.00
IUUC-Opr-070454	Ochotona princeps	90.17	2.00e-158	553.00
IUUC-Ocu-074121	Oryctolagus cuniculus	86.71	0.00e+00	946.00
IUUC-Oga-088593	Otolemur garnettii	93.90	0.00e+00	1138.00
IUUC-Oar-090140	Ovis aries	90.88	0.00e+00	1128.00
IUUC-Pan-092168	Papio anubis	97.92	0.00e+00	1182.00
IUUC-Psi-093707	Pelodiscus sinensis	67.27	0.00e+00	884.00
IUUC-Pca-100683	Procavia capensis	87.63	0.00e+00	1110.00
IUUC-Pva-103146	Pteropus vampyrus	80.21	0.00e+00	1016.00
IUUC-Rno-105061	Rattus norvegicus	91.80	0.00e+00	1145.00
IUUC-Sha-106686	Sarcophilus harrisii	72.50	0.00e+00	960.00
IUUC-Tgu-117024	Taeniopygia guttata	67.56	0.00e+00	895.00
IUUC-Tsy-119505	Tarsius syrichta	79.65	1.00e-165	577.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence