iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011062

Ensembl Protein ID

ENSAMXP00000016318.1

UniProt Accession

W5L906; W5L906_ASTMX

Genbank Protein ID

ENSAMXP00000016318

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01076196

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000015838.1	ENSAMXT00000016318.1	ENSAMXP00000016318.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-52	173.4	658	695
UBD/Beta-Prp	6.40e-94	314.7	966	1248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H d+v c+af +d ++++++s D ++kvW++ +g+ll+
   Q: 658  HDDEVLCCAFsPDdRHIATCSSDRKVKVWNVEKGTLLR 695
           9**********777*****************9999875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           ++++ks+i+c ++ ++ s +a g +dg ++v +v +g++l++l gh+++v  + f  dg++l+t+seD ti+vw  +t +c++ l g
   Q: 966  SEKQKSRIRCTCICRQASAVALGMEDGAVQVLEVPSGNTLATLLGHTKTVHHCLFTADGQTLITSSEDTTIRVWRWRTEECLI-LAG 1051
           57889999*****99******************************************************************96.677 PP
   S: 93   hedsvlslsfsp...sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           h++ v+  ++     s+  l+s s d t++vwdl+ g++l+  l+ h+g+v +  v+ dg+l+ ++s+D+t ++W+ ++ +++  l+
   Q: 1052 HKEPVRKFHLLGsssSSPALLSWSFDGTAKVWDLSCGKKLQ-DLECHKGAVLSGDVSTDGSLFSTASADKTAKVWSCASWEMVFSLK 1137
           *******77776654779***********************.9******************************************** PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght.........dnvksvrfspnderlvsgssDgsiriWdlrsg 254
           g h+  v+s  f+ +gk+l++g+++g ++lw++q+g+ ++++ + +          +v++++fsp+++ lvs++  g i+ W ++ g
   Q: 1138 G-HKACVRSCRFSWDGKRLATGDDNGEIRLWSMQNGHLLKICSCERkdsmdsfhgGWVTDLHFSPDNKVLVSTG--GYIKWWSVDRG 1221
           9.******************************************999***************************..*********** PP
   S: 255  dllktlqlhnssvisvavlsfgdnvlvl 282
           + l+t+  +  ++  + v s++ + +v+
   Q: 1222 EALQTFYTTGANLKRIHV-SPDFRTFVT 1248
           *****9888777766666.555555555 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MEERARSCLL RSKDTLEQDI KASYLMDHMI SDGVLTTDEE DRVLSKPTRR EQAAALLEVL 60
LRKDNRAYIS FYNALVRESY GDLANLLHND LPQLSPEGEK SFSNGVSSLV QLILSEGGVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATATCCGCC GGTTTATCTG ATTTAATTCA GGTGTCTTAG CAGAGCGTCG CACTAAATAA 60
AGCGTTCTTT AGTGGAGGAC TGATGCTGTA GGACTTCCGA CGCCTGTGTG AGTATGTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR017251--Apaf-1
IPR024977--Apc4_WD40_dom
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR020472--G-protein_beta_WD-40_rep
IPR002182--NB-ARC
IPR027417--P-loop_NTPase
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50209--CARD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00619--CARD
PF00931--NB-ARC
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0043293--C:apoptosome
GO:0043531--F:ADP binding
GO:0097190--P:apoptotic signaling pathway
GO:0042981--P:regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001432	Ailuropoda melanoleuca	54.07	0.00e+00	1405.00
IUUC-Apl-004201	Anas platyrhynchos	54.32	0.00e+00	1405.00
IUUC-Aca-004638	Anolis carolinensis	54.24	0.00e+00	1418.00
IUUC-Bta-012865	Bos taurus	55.10	0.00e+00	1430.00
IUUC-Cja-018815	Callithrix jacchus	51.22	0.00e+00	1261.00
IUUC-Cfa-020222	Canis familiaris	52.00	0.00e+00	1321.00
IUUC-Cpo-021524	Cavia porcellus	54.99	0.00e+00	1429.00
IUUC-Csa-023861	Chlorocebus sabaeus	54.83	0.00e+00	1418.00
IUUC-Cho-024484	Choloepus hoffmanni	45.36	0.00e+00	668.00
IUUC-Dre-028006	Danio rerio	75.27	0.00e+00	1858.00
IUUC-Dno-029591	Dasypus novemcinctus	55.07	0.00e+00	1426.00
IUUC-Dor-030237	Dipodomys ordii	42.54	1.00e-165	577.00
IUUC-Ete-032620	Echinops telfairi	52.24	0.00e+00	657.00
IUUC-Eca-033569	Equus caballus	55.07	0.00e+00	1425.00
IUUC-Eeu-035354	Erinaceus europaeus	53.44	2.00e-94	340.00
IUUC-Fca-036337	Felis catus	54.24	0.00e+00	1419.00
IUUC-Fal-037077	Ficedula albicollis	54.44	0.00e+00	1393.00
IUUC-Gmo-039687	Gadus morhua	65.61	0.00e+00	1251.00
IUUC-Gga-040299	Gallus gallus	54.00	0.00e+00	1415.00
IUUC-Gac-041762	Gasterosteus aculeatus	66.69	0.00e+00	1686.00
IUUC-Ggo-045563	Gorilla gorilla	54.99	0.00e+00	1422.00
IUUC-Hsa-046771	Homo sapiens	54.91	0.00e+00	1419.00
IUUC-Lch-050200	Latimeria chalumnae	57.58	0.00e+00	1452.00
IUUC-Loc-052090	Lepisosteus oculatus	66.46	0.00e+00	1688.00
IUUC-Laf-053861	Loxodonta africana	55.34	0.00e+00	1422.00
IUUC-Mcc-055543	Macaca mulatta	54.99	0.00e+00	1420.00
IUUC-Meu-056688	Macropus eugenii	55.39	0.00e+00	1402.00
IUUC-Mga-059243	Meleagris gallopavo	53.92	0.00e+00	1408.00
IUUC-Mmr-061134	Microcebus murinus	51.74	0.00e+00	1191.00
IUUC-Mdo-062913	Monodelphis domestica	55.58	0.00e+00	1416.00
IUUC-Mmu-063811	Mus musculus	54.60	0.00e+00	1419.00
IUUC-Mpu-066780	Mustela putorius furo	54.24	0.00e+00	1404.00
IUUC-Mlu-067276	Myotis lucifugus	54.71	0.00e+00	1417.00
IUUC-Nle-069129	Nomascus leucogenys	54.75	0.00e+00	1412.00
IUUC-Opr-071007	Ochotona princeps	41.20	1.00e-179	624.00
IUUC-Ont-071348	Oreochromis niloticus	71.13	0.00e+00	1847.00
IUUC-Oan-072717	Ornithorhynchus anatinus	56.37	0.00e+00	1473.00
IUUC-Ocu-074286	Oryctolagus cuniculus	54.50	0.00e+00	1182.00
IUUC-Ola-086895	Oryzias latipes	62.50	0.00e+00	1536.00
IUUC-Oga-088678	Otolemur garnettii	54.91	0.00e+00	1420.00
IUUC-Oar-089359	Ovis aries	55.39	0.00e+00	1436.00
IUUC-Ptr-091062	Pan troglodytes	54.83	0.00e+00	1418.00
IUUC-Pan-092528	Papio anubis	59.21	0.00e+00	896.00
IUUC-Psi-093430	Pelodiscus sinensis	56.49	0.00e+00	1446.00
IUUC-Pma-094690	Petromyzon marinus	39.39	2.00e-148	519.00
IUUC-Pfo-097204	Poecilia formosa	67.91	0.00e+00	1763.00
IUUC-Pab-097690	Pongo abelii	55.19	0.00e+00	1419.00
IUUC-Pca-100778	Procavia capensis	42.25	0.00e+00	664.00
IUUC-Pva-102870	Pteropus vampyrus	53.30	0.00e+00	1254.00
IUUC-Rno-104889	Rattus norvegicus	54.68	0.00e+00	1414.00
IUUC-Sha-107465	Sarcophilus harrisii	55.02	0.00e+00	1432.00
IUUC-Sar-113268	Sorex araneus	50.70	3.00e-106	380.00
IUUC-Ssc-115654	Sus scrofa	54.75	0.00e+00	1428.00
IUUC-Tgu-117302	Taeniopygia guttata	54.33	0.00e+00	1401.00
IUUC-Tru-118363	Takifugu rubripes	70.34	0.00e+00	1819.00
IUUC-Tsy-119007	Tarsius syrichta	52.61	0.00e+00	1340.00
IUUC-Tni-120910	Tetraodon nigroviridis	69.55	0.00e+00	1773.00
IUUC-Tbe-127413	Tupaia belangeri	44.78	0.00e+00	795.00
IUUC-Ttr-129213	Tursiops truncatus	51.19	0.00e+00	1271.00
IUUC-Vpa-130146	Vicugna pacos	50.58	0.00e+00	950.00
IUUC-Xtr-132559	Xenopus tropicalis	51.27	0.00e+00	1323.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence