iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Vda-129857

Ensembl Protein ID

EGY18855

UniProt Accession

G2XG36; G2XG36_VERDV

Genbank Protein ID

EGY18855.1

Protein Name

Cullin-1

Genbank Nucleotide ID

DS572718

Gene Name

VDAG_09015

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VDAG_09015	EGY18855	EGY18855

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	6.70e-181	602.2	47	675

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 21   elytavynlclsk............................vgaklYkklkevleefikqvkkkveesedeqlLktynreWekfreqlkvlrkifayldrt 93
             y +vy++ l                              +g++lYkkl  +l+++++ + ++ + +++e+lL++y+reW+++++++k+++++f+yl+r+
   Q: 47   HTYMGVYTYSLTRtptpstaiglgvsaapsigsgnhrgahlLGEELYKKLTDYLVAHLQGLLAESKTHTNEALLAFYIREWTRYTNAAKYIHHLFRYLNRH 147
           67889999999888999999999999999999999999999************************************************************ PP
   S: 94   yvkk.....skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk.......laiykesFEakfleatqefyka 182
           +vk+     +k+ ++v++L l  wr+e++++i++++++++lkl+e++R+ge+++ + +++vv s+v+L+l++       l+iy+  FE++fleat+++y++
   Q: 148  WVKRemdegKKNTYDVYTLHLVQWREELFKKISDKVMDAVLKLVEKQRNGETIEFSQIKQVVDSYVSLGLDEtdptrstLEIYRFHFEKPFLEATAKYYQN 248
           ****999988899**************************************************************************************** PP
   S: 183  esaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllaelvallrdkktedlsrmykLlsrvlngleellkeleshikeq 283
           es++f++en + eY+kk+e+rl eeeer++ yl++  + +L +++e +li++h+  l +e++ ll++++++d++rmy Ll r+++gl+ l++++e+h++++
   Q: 249  ESKHFVAENTIVEYMKKAEERLDEEEERVRMYLHADILASLRKTCETALITDHASVLRDEFQVLLENDREQDMARMYGLLLRIPEGLDALRQKFETHVRKA 349
           ***************************************************************************************************** PP
   S: 284  gkaalt....aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlka..akspEllAryiDqlLrksskglteeeleaqldk 378
           g+ a++    +++++ +pk yV  lle++ +++ lvs+aF ++a+F+ +ld+a+++fvn+n++ k    kspEllA+y D lLrks  g++e ele++l++
   Q: 350  GLGAIQkvasENTEKLEPKVYVDALLEVHTQYSGLVSRAFREEAEFTRSLDNACKEFVNRNEICKSgsNKSPELLAKYTDVLLRKSGTGIEETELENTLTQ 450
           **999977544444449************************************************998999****************************** PP
   S: 379  vllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeekente.esesvelsvlvLsagaWpt 478
           +++vfkyi++kdvF+k+Y ++La+RL++ +s s++aE s+i+kLke+cg+e+t+kL+rMfqd+++S+dln+ ++e+ +  e +++ ++ + ++L +g+Wp 
   Q: 451  IMIVFKYIEDKDVFQKFYSRMLARRLVHSNSSSDDAETSMISKLKEACGFEYTNKLQRMFQDMQISKDLNNSYREHCNGLEnAKNILDSQYSILGTGFWPL 551
           **************************************************************************987755405567899************ PP
   S: 479  asetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkg...kyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLv 576
           ++   +++ Pae+++  e+f++fY++kh+gRkL+W+++l+++elka + k    +y++qVs +QmavLL+fn++++ s+++++ at l++e+L ++l  L+
   Q: 552  QAPNTNFTPPAEINEETERFSRFYKNKHEGRKLTWLWQLCKGELKAGYCKAsktPYTFQVSIYQMAVLLLFNEKDSHSYDDIAGATLLSNEVLDQALAILL 652
           *77777***************************************987444455*********************************************** PP
   S: 577  sskkqvlkkepeskeieeedlfsvNq 602
           + k  vl   pe+k  e+++ + +N 
   Q: 653  KAK--VLLIFPEGKP-ESGKELRLNY 675
           *98..8877777665.5566666665 PP

Organism

Verticillium dahliae

Protein Sequence
(Fasta)

MATPKRTNSP AAMPPAPNRE DALATWNYLE AGIERIMLHL ESGIDMHTYM GVYTYSLTRT 60
PTPSTAIGLG VSAAPSIGSG NHRGAHLLGE ELYKKLTDYL VAHLQGLLAE SKTHTNEALL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACGC CCAAGAGGAC CAACTCGCCG GCGGCGATGC CTCCCGCGCC TAACCGCGAG 60
GATGCTTTGG CGACGTACGC TTCCGCGCTC ATACTGCCAC GACACACAGG GCCCGGCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0005829--C:cytosol
GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:1903467--P:negative regulation of mitotic DNA replication initiation
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

vda:VDAG_09015

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002277	Ailuropoda melanoleuca	47.40	0.00e+00	644.00
IUUC-Apl-003503	Anas platyrhynchos	46.74	8.00e-150	521.00
IUUC-Aca-005030	Anolis carolinensis	42.05	2.00e-139	487.00
IUUC-Ago-007977	Ashbya gossypii	30.95	3.00e-116	410.00
IUUC-Acl-008190	Aspergillus clavatus	63.93	0.00e+00	950.00
IUUC-Afl-008542	Aspergillus flavus	63.81	0.00e+00	792.00
IUUC-Afu-009007	Aspergillus fumigatus	66.52	0.00e+00	898.00
IUUC-Ani-009290	Aspergillus nidulans	63.85	0.00e+00	989.00
IUUC-Ang-009600	Aspergillus niger	67.26	0.00e+00	931.00
IUUC-Aor-009978	Aspergillus oryzae	64.60	0.00e+00	857.00
IUUC-Ate-010584	Aspergillus terreus	65.37	0.00e+00	978.00
IUUC-Ame-011861	Astyanax mexicanus	47.27	0.00e+00	631.00
IUUC-Bgr-012209	Blumeria graminis	67.96	0.00e+00	988.00
IUUC-Bta-012878	Bos taurus	47.27	0.00e+00	644.00
IUUC-Bci-013941	Botrytis cinerea	71.52	0.00e+00	1117.00
IUUC-Cel-018294	Caenorhabditis elegans	38.17	7.00e-144	502.00
IUUC-Cja-018965	Callithrix jacchus	46.23	0.00e+00	626.00
IUUC-Cfa-020671	Canis familiaris	47.27	0.00e+00	644.00
IUUC-Cpo-021762	Cavia porcellus	47.27	0.00e+00	644.00
IUUC-Csa-023873	Chlorocebus sabaeus	47.27	0.00e+00	644.00
IUUC-Cin-025547	Ciona intestinalis	45.53	5.00e-168	582.00
IUUC-Csv-026083	Ciona savignyi	45.67	7.00e-178	615.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	82.59	0.00e+00	1278.00
IUUC-Cne-026919	Cryptococcus neoformans	45.80	0.00e+00	638.00
IUUC-Dre-028777	Danio rerio	47.01	0.00e+00	625.00
IUUC-Dno-028931	Dasypus novemcinctus	47.27	0.00e+00	640.00
IUUC-Dor-030846	Dipodomys ordii	49.71	1.00e-131	462.00
IUUC-Dse-031472	Dothistroma septosporum	61.47	0.00e+00	905.00
IUUC-Dme-031793	Drosophila melanogaster	43.04	3.00e-168	583.00
IUUC-Ete-033112	Echinops telfairi	44.83	2.00e-70	258.00
IUUC-Eca-034309	Equus caballus	47.27	0.00e+00	644.00
IUUC-Fca-036330	Felis catus	46.30	3.00e-180	623.00
IUUC-Fal-036899	Ficedula albicollis	46.01	3.00e-154	536.00
IUUC-Fox-037705	Fusarium oxysporum	72.45	0.00e+00	1122.00
IUUC-Fso-038367	Fusarium solani	74.94	0.00e+00	1165.00
IUUC-Gmo-038708	Gadus morhua	47.21	1.00e-180	625.00
IUUC-Ggr-039917	Gaeumannomyces graminis	71.96	0.00e+00	1122.00
IUUC-Gga-041038	Gallus gallus	47.27	0.00e+00	644.00
IUUC-Gac-041820	Gasterosteus aculeatus	47.21	0.00e+00	656.00
IUUC-Ggo-045154	Gorilla gorilla	39.92	1.00e-124	438.00
IUUC-Hsa-046034	Homo sapiens	47.27	0.00e+00	644.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	47.27	0.00e+00	644.00
IUUC-Kpa-049231	Komagataella pastoris	36.28	6.00e-134	469.00
IUUC-Lch-049673	Latimeria chalumnae	47.27	0.00e+00	640.00
IUUC-Loc-052490	Lepisosteus oculatus	47.72	0.00e+00	634.00
IUUC-Lma-053191	Leptosphaeria maculans	64.01	0.00e+00	986.00
IUUC-Laf-054582	Loxodonta africana	47.27	0.00e+00	644.00
IUUC-Mcc-055162	Macaca mulatta	46.61	0.00e+00	629.00
IUUC-Meu-055904	Macropus eugenii	45.53	1.00e-69	256.00
IUUC-Mor-057035	Magnaporthe oryzae	72.63	0.00e+00	1094.00
IUUC-Mpo-057555	Magnaporthe poae	71.58	0.00e+00	1118.00
IUUC-Mla-059021	Melampsora laricipopulina	49.74	0.00e+00	689.00
IUUC-Mga-060078	Meleagris gallopavo	47.27	0.00e+00	644.00
IUUC-Mvi-060519	Microbotryum violaceum	49.55	0.00e+00	714.00
IUUC-Mmr-061312	Microcebus murinus	47.27	0.00e+00	644.00
IUUC-Mdo-062867	Monodelphis domestica	47.14	0.00e+00	640.00
IUUC-Mmu-063336	Mus musculus	47.27	0.00e+00	644.00
IUUC-Mpu-066400	Mustela putorius furo	46.01	2.00e-154	537.00
IUUC-Mlu-067800	Myotis lucifugus	47.27	0.00e+00	644.00
IUUC-Nfi-068384	Neosartorya fischeri	63.16	0.00e+00	933.00
IUUC-Ncr-068965	Neurospora crassa	70.13	0.00e+00	1079.00
IUUC-Nle-069729	Nomascus leucogenys	47.27	0.00e+00	644.00
IUUC-Opr-071197	Ochotona princeps	33.77	5.00e-102	363.00
IUUC-Ont-071729	Oreochromis niloticus	47.26	0.00e+00	634.00
IUUC-Oan-073309	Ornithorhynchus anatinus	47.27	0.00e+00	644.00
IUUC-Ocu-074661	Oryctolagus cuniculus	47.14	0.00e+00	630.00
IUUC-Ola-087422	Oryzias latipes	47.46	0.00e+00	642.00
IUUC-Oga-088130	Otolemur garnettii	47.27	0.00e+00	644.00
IUUC-Oar-089510	Ovis aries	46.13	4.00e-174	603.00
IUUC-Ptr-090665	Pan troglodytes	47.27	0.00e+00	644.00
IUUC-Pan-092218	Papio anubis	47.27	0.00e+00	644.00
IUUC-Psi-093175	Pelodiscus sinensis	47.27	0.00e+00	644.00
IUUC-Pma-094502	Petromyzon marinus	45.93	0.00e+00	627.00
IUUC-Pno-095067	Phaeosphaeria nodorum	65.18	0.00e+00	1001.00
IUUC-Pfo-096705	Poecilia formosa	47.66	0.00e+00	661.00
IUUC-Pab-097578	Pongo abelii	47.27	0.00e+00	644.00
IUUC-Pca-100242	Procavia capensis	50.20	8.00e-137	479.00
IUUC-Pva-102155	Pteropus vampyrus	40.94	1.00e-155	541.00
IUUC-Pgr-103297	Puccinia graminis	48.73	0.00e+00	705.00
IUUC-Ptt-103706	Puccinia triticina	47.87	1.00e-104	373.00
IUUC-Pte-104257	Pyrenophora teres	65.76	0.00e+00	1004.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	65.63	0.00e+00	1003.00
IUUC-Rno-105939	Rattus norvegicus	47.27	0.00e+00	644.00
IUUC-Sce-106293	Saccharomyces cerevisiae	31.01	1.00e-118	419.00
IUUC-Sha-106949	Sarcophilus harrisii	47.27	0.00e+00	644.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	45.09	4.00e-171	593.00
IUUC-Spo-108280	Schizosaccharomyces pombe	45.12	5.00e-177	612.00
IUUC-Sar-113138	Sorex araneus	36.79	1.00e-121	428.00
IUUC-Sre-114984	Sporisorium reilianum	48.52	0.00e+00	661.00
IUUC-Ssc-115829	Sus scrofa	46.88	0.00e+00	634.00
IUUC-Tgu-116950	Taeniopygia guttata	47.27	0.00e+00	644.00
IUUC-Tru-118558	Takifugu rubripes	46.72	0.00e+00	648.00
IUUC-Tsy-119621	Tarsius syrichta	38.39	9.00e-97	346.00
IUUC-Tni-120460	Tetraodon nigroviridis	46.46	0.00e+00	652.00
IUUC-Tre-122223	Trichoderma reesei	74.35	0.00e+00	1122.00
IUUC-Tvi-122539	Trichoderma virens	72.03	0.00e+00	1078.00
IUUC-Tme-126926	Tuber melanosporum	66.02	0.00e+00	978.00
IUUC-Tbe-127369	Tupaia belangeri	52.01	1.00e-88	319.00
IUUC-Ttr-129022	Tursiops truncatus	47.04	4.00e-144	503.00
IUUC-Uma-129341	Ustilago maydis	47.98	2.00e-179	620.00
IUUC-Vpa-130166	Vicugna pacos	42.56	1.00e-133	468.00
IUUC-Xtr-131818	Xenopus tropicalis	47.53	0.00e+00	640.00
IUUC-Xma-134206	Xiphophorus maculatus	47.53	0.00e+00	635.00
IUUC-Yli-134486	Yarrowia lipolytica	41.79	5.00e-164	569.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence