iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052849

Ensembl Protein ID

ENSLOCP00000010864.1

UniProt Accession

W5MR55; W5MR55_LEPOC

Genbank Protein ID

ENSLOCP00000010864

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01016274

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000008918.1	ENSLOCT00000010880.1	ENSLOCP00000010864.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-82	276.5	319	917
UBD/Alpha-Helix/UIM	1.50e-07	30.9	774	791
UBD/Alpha-Helix/UIM	0.00011	12.8	795	813

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +G++NlgNtCYmN++LQ+L++++++ ++ll+   + ++++  k p ++ll+ +++l+++    + + k+   ++++++++++ae+fsgy
   Q: 319  QGFSNLGNTCYMNAILQSLFSLQSFSNDLLK---QGIPWK--KVPINALLRRFAHLLAKKDicSPEVKKDLLKKVKSSISTTAERFSGY 402
           69*****************************...*****9..56999999999999998867799999999****************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeee..dkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           +q+Da+Efl+++ldql+e+++k  nk++++e ++  d + +   +e    + ++++++ +++++++++i+c+ c+++ +++e+f+dls+
   Q: 403  MQNDAHEFLSQCLDQLKEDVEK-VNKTWKNEPQSweDPQGARPGEEATSSRIYTCPVVVNMEFEVQHTITCKGCGEIVTKREQFNDLSI 490
           ********************66.5555555544400333444447777888889*********************************** PP
   S: 175  pvpgkeetkke.slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           ++p++++t ++ s+qd+L+ f++ ee+e    y+cekc +k+ a+ ++k++klP+vLilhLkR+s++ + + ++k+ ++v +p+ L+l 
   Q: 491  DLPRRKKTLPLrSIQDSLDLFFRVEEIE----YSCEKCSGKS-ATVMHKFSKLPRVLILHLKRYSYNAQLSLNSKLGQQVLIPKYLTLL 574
           ***999887645***************9....********99.9********************************************* PP
   S: 263  pfcts.................................................................................... 267
           ++ct+                                                                                    
   Q: 575  SHCTDstrpplslgwnansaasrtlkasqsvnstipafrkgslkpgsstmtildsdseeeltrkivsrsrrlsespqeedrtekptrrp 663
           *****999999999999999999999999999999999999999999999999999999999999999999999988888888888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 664  qmehplpgydgmndeemlaavlemsrqenmrsgspedeptsspdtgfgegdgqdlaqhtdlfdsdrpassdvldsldltkdldenkenq 752
           88888888888888888888888888888888887777777777777777777777777777777777777777777777776666665 PP
   S: 268  .............peekqke..................................................................... 274
                        +                                                                           
   Q: 753  tpeeaqgeldwvqQ-----Ysldqereeqelqqalaqslqehearemkedddlkratelslqefnnslpeclcsdedsgnedvldmeys 836
           55555555555550.....0555555555566666666666667777777777777777777777778888888888888888888888 PP
   S: 275  ................kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
                           +++++L++vv+H G s+ssGHY+++v++ k++ Wl+++D  V+ ++e+ v++++++++Y++fY++
   Q: 837  eteaedlkrnaesgelPHSFRLVSVVSHIGsSSSSGHYISDVYDIKKQcWLTYNDLDVSRTQETAVQRDRDRSGYIFFYMH 917
           8888889999999999****************************99989******************************98 PP

UBD/Alpha-Helix/UIM

   S: 2    EdeeLqlAlalSlqEeee 19
           E++eLq+Ala+SlqE+e 
   Q: 774  EEQELQQALAQSLQEHEA 791
           9***************96 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +Ed++L +A +lSlqE ++
   Q: 795  KEDDDLKRATELSLQEFNN 813
           69**************876 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MAATVPKLLG SVRINSLQLG TTKWKEGSFE IHEKDNKVNL FVRFNSGGVP KIFQLNQNVK 60
TVSLGPKQNQ CRIQVVLKDS SSLIIDKVPL LLAQKFRDYL EKLKQGKQTV LKPSQGTVSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGCCA CTGTGCCAAA ACTGTTAGGC AGCGTCCGGA TCAACAGCCT GCAACTGGGT 60
ACCACCAAGT GGAAGGAAGG AAGCTTTGAG ATCCACGAGA AGGACAACAA AGTCAACCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N
PF02809--UIM

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001400	Ailuropoda melanoleuca	60.83	0.00e+00	1014.00
IUUC-Apl-004033	Anas platyrhynchos	62.64	0.00e+00	1078.00
IUUC-Aca-005370	Anolis carolinensis	60.29	0.00e+00	1024.00
IUUC-Ame-011884	Astyanax mexicanus	72.61	0.00e+00	1259.00
IUUC-Bta-012725	Bos taurus	60.16	0.00e+00	1001.00
IUUC-Cja-019939	Callithrix jacchus	60.41	0.00e+00	1004.00
IUUC-Cfa-020835	Canis familiaris	61.17	0.00e+00	1037.00
IUUC-Cpo-022067	Cavia porcellus	59.03	0.00e+00	910.00
IUUC-Cre-022867	Chlamydomonas reinhardtii	27.60	7.00e-24	105.00
IUUC-Csa-023085	Chlorocebus sabaeus	60.83	0.00e+00	1023.00
IUUC-Cho-024390	Choloepus hoffmanni	45.89	9.00e-74	271.00
IUUC-Cin-025496	Ciona intestinalis	38.87	4.00e-42	166.00
IUUC-Csv-025812	Ciona savignyi	32.50	1.00e-37	151.00
IUUC-Dre-028255	Danio rerio	69.77	0.00e+00	1194.00
IUUC-Dno-028986	Dasypus novemcinctus	60.57	0.00e+00	1003.00
IUUC-Dor-031062	Dipodomys ordii	50.26	7.00e-147	514.00
IUUC-Ete-032359	Echinops telfairi	55.47	8.00e-142	498.00
IUUC-Eca-033964	Equus caballus	61.48	0.00e+00	1017.00
IUUC-Eeu-034492	Erinaceus europaeus	58.68	4.00e-138	485.00
IUUC-Fca-036359	Felis catus	61.09	0.00e+00	1022.00
IUUC-Fal-037640	Ficedula albicollis	63.02	0.00e+00	1057.00
IUUC-Gmo-039600	Gadus morhua	70.73	0.00e+00	1184.00
IUUC-Gga-040126	Gallus gallus	62.17	0.00e+00	1024.00
IUUC-Gac-041557	Gasterosteus aculeatus	69.11	0.00e+00	1146.00
IUUC-Ggo-045571	Gorilla gorilla	57.62	0.00e+00	882.00
IUUC-Hsa-046043	Homo sapiens	60.45	0.00e+00	1009.00
IUUC-Itr-048207	Ictidomys tridecemlineatus	60.98	0.00e+00	1008.00
IUUC-Lch-050357	Latimeria chalumnae	60.35	0.00e+00	885.00
IUUC-Laf-054570	Loxodonta africana	59.53	0.00e+00	978.00
IUUC-Mcc-054989	Macaca mulatta	59.75	0.00e+00	932.00
IUUC-Meu-056273	Macropus eugenii	53.30	9.00e-48	185.00
IUUC-Mga-059814	Meleagris gallopavo	60.81	0.00e+00	1009.00
IUUC-Mmr-061726	Microcebus murinus	61.32	0.00e+00	1018.00
IUUC-Mdo-062974	Monodelphis domestica	62.40	0.00e+00	1043.00
IUUC-Mmu-064069	Mus musculus	60.04	0.00e+00	984.00
IUUC-Mpu-066008	Mustela putorius furo	60.55	0.00e+00	1009.00
IUUC-Mlu-068224	Myotis lucifugus	34.76	9.00e-108	384.00
IUUC-Nle-069259	Nomascus leucogenys	60.35	0.00e+00	1007.00
IUUC-Opr-070882	Ochotona princeps	78.03	5.00e-91	329.00
IUUC-Ont-072441	Oreochromis niloticus	70.59	0.00e+00	1178.00
IUUC-Oan-073151	Ornithorhynchus anatinus	71.65	6.00e-95	340.00
IUUC-Ocu-074879	Oryctolagus cuniculus	60.53	0.00e+00	1000.00
IUUC-Ola-087007	Oryzias latipes	66.49	0.00e+00	1070.00
IUUC-Oga-088385	Otolemur garnettii	61.17	0.00e+00	1023.00
IUUC-Oar-090305	Ovis aries	60.61	0.00e+00	1021.00
IUUC-Ptr-091299	Pan troglodytes	60.47	0.00e+00	1008.00
IUUC-Pan-091996	Papio anubis	61.44	0.00e+00	1001.00
IUUC-Psi-093176	Pelodiscus sinensis	63.02	0.00e+00	1070.00
IUUC-Pma-094331	Petromyzon marinus	45.92	0.00e+00	678.00
IUUC-Ppa-095685	Physcomitrella patens	28.84	4.00e-23	103.00
IUUC-Pfo-096503	Poecilia formosa	69.27	0.00e+00	1129.00
IUUC-Pab-098543	Pongo abelii	63.26	2.00e-166	579.00
IUUC-Pca-101099	Procavia capensis	58.78	0.00e+00	788.00
IUUC-Pva-103163	Pteropus vampyrus	58.66	0.00e+00	682.00
IUUC-Rno-105766	Rattus norvegicus	59.12	0.00e+00	966.00
IUUC-Sha-106610	Sarcophilus harrisii	58.48	0.00e+00	947.00
IUUC-Sar-113624	Sorex araneus	36.86	3.00e-68	253.00
IUUC-Ssc-116353	Sus scrofa	60.04	0.00e+00	989.00
IUUC-Tgu-116971	Taeniopygia guttata	63.32	0.00e+00	1046.00
IUUC-Tru-117932	Takifugu rubripes	51.72	0.00e+00	771.00
IUUC-Tsy-119185	Tarsius syrichta	58.19	0.00e+00	689.00
IUUC-Tni-119842	Tetraodon nigroviridis	68.21	1.00e-121	430.00
IUUC-Tbe-127281	Tupaia belangeri	47.76	7.00e-93	335.00
IUUC-Ttr-128177	Tursiops truncatus	65.13	0.00e+00	836.00
IUUC-Vpa-130031	Vicugna pacos	60.67	0.00e+00	1017.00
IUUC-Xtr-132949	Xenopus tropicalis	59.37	0.00e+00	963.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence