iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021777

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02021612

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000006299.3	ENSCPOT00000006364.2	ENSCPOP00000015242.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-42	142.1	508	542
UBD/Beta-Prp	1.50e-67	227.8	271	560

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gHtds+t+laf +d +l++s+s D++++vWDlr  
   Q: 508  GHTDSITSLAFsPDsGLVASASMDNSVRVWDLRNT 542
           8***********999****************9875 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   ++pd++lla+g+++++ik+w+++++kl                                ++ l gh ++v++++f +d++ l++
   Q: 271  LNTAEIAPDSKLLAAGFDNSCIKLWSLRSKKLksephlvdtsrirlacdtleeeedeednigteMKILRGHCGPVYSTRFLSDSSGLLS 359
           5667789********************************************************99999********************* PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp++ +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVRFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtd ++s++fsp++ +++s+s+D+s+r
   Q: 448  KTVRLWSTQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLVASASMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvav 272
           +Wdlr+  + +   ++ s ++ v +
   Q: 536  VWDLRNTCCSTPADGSSSELVGVYT 560
           **99999998888888755555544 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MKRVRTEHVQ MAVSCYLKRR QYVDSDGPLK QGLRLSQTAE EMAANLTVQS ESGCANIVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQYSH EVMPLLYPLF VYLHLSLVQN SPKSTVESFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAACGGG TGCGCACCGA GCACGTCCAG ATGGCAGTGT CCTGCTACCT CAAGCGCCGG 60
CAGTACGTGG ATTCCGATGG CCCCCTGAAG CAAGGCCTGC GTCTGTCTCA GACTGCTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	94.23	0.00e+00	1074.00
IUUC-Apl-003636	Anas platyrhynchos	90.19	0.00e+00	1089.00
IUUC-Aca-004229	Anolis carolinensis	89.64	0.00e+00	1056.00
IUUC-Ame-010599	Astyanax mexicanus	66.89	0.00e+00	815.00
IUUC-Bta-013404	Bos taurus	90.83	0.00e+00	1032.00
IUUC-Cja-019643	Callithrix jacchus	95.08	0.00e+00	1086.00
IUUC-Cfa-020913	Canis familiaris	94.74	0.00e+00	1078.00
IUUC-Csa-024184	Chlorocebus sabaeus	95.08	0.00e+00	1088.00
IUUC-Cho-024638	Choloepus hoffmanni	95.08	0.00e+00	1071.00
IUUC-Cin-025618	Ciona intestinalis	35.46	2.00e-90	326.00
IUUC-Csv-025874	Ciona savignyi	34.85	5.00e-90	325.00
IUUC-Dre-028817	Danio rerio	66.61	0.00e+00	797.00
IUUC-Dno-029969	Dasypus novemcinctus	87.44	0.00e+00	1024.00
IUUC-Dor-031117	Dipodomys ordii	95.25	0.00e+00	1110.00
IUUC-Ete-032712	Echinops telfairi	87.44	0.00e+00	969.00
IUUC-Eca-033742	Equus caballus	94.40	0.00e+00	1076.00
IUUC-Eeu-035096	Erinaceus europaeus	92.71	0.00e+00	1088.00
IUUC-Fca-035769	Felis catus	93.74	0.00e+00	1093.00
IUUC-Fal-036645	Ficedula albicollis	90.29	0.00e+00	1030.00
IUUC-Gmo-038636	Gadus morhua	66.00	0.00e+00	764.00
IUUC-Gga-040144	Gallus gallus	90.32	0.00e+00	1060.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.06	0.00e+00	803.00
IUUC-Ggo-044568	Gorilla gorilla	95.25	0.00e+00	1088.00
IUUC-Hsa-046178	Homo sapiens	95.25	0.00e+00	1088.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	89.64	0.00e+00	1083.00
IUUC-Lch-050501	Latimeria chalumnae	76.95	0.00e+00	850.00
IUUC-Loc-052895	Lepisosteus oculatus	81.47	0.00e+00	630.00
IUUC-Laf-053950	Loxodonta africana	90.66	0.00e+00	1044.00
IUUC-Mcc-055450	Macaca mulatta	95.08	0.00e+00	1084.00
IUUC-Meu-056182	Macropus eugenii	87.10	0.00e+00	999.00
IUUC-Mga-059619	Meleagris gallopavo	90.49	0.00e+00	1063.00
IUUC-Mmr-061074	Microcebus murinus	94.25	0.00e+00	1096.00
IUUC-Mdo-062307	Monodelphis domestica	93.33	0.00e+00	890.00
IUUC-Mmu-063226	Mus musculus	93.72	0.00e+00	1060.00
IUUC-Mpu-066016	Mustela putorius furo	94.57	0.00e+00	1073.00
IUUC-Mlu-067257	Myotis lucifugus	87.31	0.00e+00	1065.00
IUUC-Nle-070139	Nomascus leucogenys	95.08	0.00e+00	1085.00
IUUC-Opr-070243	Ochotona princeps	90.49	0.00e+00	1059.00
IUUC-Ont-072686	Oreochromis niloticus	67.83	0.00e+00	820.00
IUUC-Oan-073670	Ornithorhynchus anatinus	82.90	0.00e+00	818.00
IUUC-Ocu-074525	Oryctolagus cuniculus	94.91	0.00e+00	1107.00
IUUC-Ola-086524	Oryzias latipes	67.67	0.00e+00	837.00
IUUC-Oga-088540	Otolemur garnettii	94.57	0.00e+00	1078.00
IUUC-Oar-089793	Ovis aries	87.95	0.00e+00	966.00
IUUC-Ptr-091154	Pan troglodytes	95.25	0.00e+00	1088.00
IUUC-Pan-092759	Papio anubis	95.08	0.00e+00	1084.00
IUUC-Psi-094008	Pelodiscus sinensis	87.95	0.00e+00	1056.00
IUUC-Pma-094593	Petromyzon marinus	45.30	2.00e-130	459.00
IUUC-Pfo-097409	Poecilia formosa	66.56	0.00e+00	797.00
IUUC-Pab-097946	Pongo abelii	83.19	0.00e+00	930.00
IUUC-Pca-100727	Procavia capensis	87.10	0.00e+00	973.00
IUUC-Pva-103211	Pteropus vampyrus	83.02	0.00e+00	998.00
IUUC-Ptt-103995	Puccinia triticina	43.83	3.00e-69	257.00
IUUC-Rno-105236	Rattus norvegicus	93.89	0.00e+00	1064.00
IUUC-Sha-106833	Sarcophilus harrisii	91.89	0.00e+00	1073.00
IUUC-Sar-113381	Sorex araneus	94.23	0.00e+00	1105.00
IUUC-Ssc-116421	Sus scrofa	92.36	0.00e+00	1110.00
IUUC-Tgu-117143	Taeniopygia guttata	91.00	0.00e+00	1096.00
IUUC-Tru-118680	Takifugu rubripes	66.67	0.00e+00	822.00
IUUC-Tsy-119622	Tarsius syrichta	79.80	0.00e+00	829.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.17	0.00e+00	828.00
IUUC-Ttr-129171	Tursiops truncatus	91.17	0.00e+00	1041.00
IUUC-Xtr-132241	Xenopus tropicalis	78.81	0.00e+00	926.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence