iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-21	72.7	129	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           +++++l++  d ++l++G+ D++++++D +tg l
   Q: 129  SEIYDLCWsVDsNFLIAGAMDNSLRLYDAHTGQL 162
           689******666****************999976 PP

Organism

Schizosaccharomyces pombe

Protein Sequence
(Fasta)

MRAEVLQIRW HYDANDDHTP IYSVDFQKNS LNKFATCGGD SKIRIWQLIT SESSTKVEYL 60
STLSRHTQAV NVVRFNPEGN ILATAGDEGT IMLWVPTNTP ITTLADDAEE LALAKEYWKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTGATCCA AGACTTGTAA ACTACGCGTT TTAAACCCTC AAATTTTGTA CTCTATTATA 60
TGAAATACTC TGTTTTTAAA CCAAGGGGAA AGGATGCAAT TTCAACTGTG AAAGTCCATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0033186--C:CAF-1 complex
GO:0005829--C:cytosol
GO:0043596--C:nuclear replication fork
GO:0005634--C:nucleus
GO:0042393--F:histone binding
GO:0006338--P:chromatin remodeling
GO:0006335--P:DNA replication-dependent nucleosome assembly
GO:0070829--P:heterochromatin maintenance
GO:1990426--P:mitotic recombination-dependent replication fork processing
GO:0006334--P:nucleosome assembly

KEGG

spo:SPAC26H5.03

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000474	Aegilops tauschii	36.17	2.00e-66	244.00
IUUC-Aml-001755	Ailuropoda melanoleuca	33.76	6.00e-72	263.00
IUUC-Atr-002674	Amborella trichopoda	33.99	3.00e-65	240.00
IUUC-Apl-003701	Anas platyrhynchos	33.08	7.00e-73	266.00
IUUC-Aca-004692	Anolis carolinensis	33.60	8.00e-74	269.00
IUUC-Aly-006286	Arabidopsis lyrata	32.39	3.00e-62	230.00
IUUC-Ath-007683	Arabidopsis thaliana	32.61	3.00e-62	230.00
IUUC-Ago-007940	Ashbya gossypii	36.53	7.00e-69	252.00
IUUC-Acl-008070	Aspergillus clavatus	45.25	3.00e-60	224.00
IUUC-Afl-008414	Aspergillus flavus	44.81	2.00e-61	228.00
IUUC-Afu-009046	Aspergillus fumigatus	35.85	1.00e-23	102.00
IUUC-Ani-009399	Aspergillus nidulans	47.06	4.00e-60	224.00
IUUC-Ang-009650	Aspergillus niger	44.78	9.00e-59	219.00
IUUC-Aor-009937	Aspergillus oryzae	44.81	2.00e-61	228.00
IUUC-Ate-010505	Aspergillus terreus	39.82	4.00e-42	163.00
IUUC-Ame-011094	Astyanax mexicanus	28.30	3.00e-51	194.00
IUUC-Bgr-012005	Blumeria graminis	45.10	1.00e-52	199.00
IUUC-Bta-013423	Bos taurus	31.98	1.00e-73	268.00
IUUC-Bci-013847	Botrytis cinerea	46.67	3.00e-59	221.00
IUUC-Bdi-014860	Brachypodium distachyon	33.90	2.00e-63	234.00
IUUC-Bol-016603	Brassica oleracea	31.76	2.00e-58	218.00
IUUC-Bra-017175	Brassica rapa	31.96	2.00e-55	207.00
IUUC-Cel-018272	Caenorhabditis elegans	27.30	1.00e-31	129.00
IUUC-Cja-019558	Callithrix jacchus	33.69	1.00e-72	265.00
IUUC-Cfa-020900	Canis familiaris	32.50	1.00e-71	261.00
IUUC-Cpo-022054	Cavia porcellus	32.49	4.00e-62	230.00
IUUC-Csa-023850	Chlorocebus sabaeus	32.95	5.00e-76	276.00
IUUC-Cho-024510	Choloepus hoffmanni	37.27	6.00e-29	120.00
IUUC-Cin-025178	Ciona intestinalis	31.52	9.00e-59	219.00
IUUC-Csv-025885	Ciona savignyi	34.01	1.00e-19	86.70
IUUC-Cgl-026572	Colletotrichum gloeosporioides	52.69	7.00e-52	196.00
IUUC-Cne-027015	Cryptococcus neoformans	39.17	8.00e-43	166.00
IUUC-Cme-027136	Cyanidioschyzon merolae	26.90	2.00e-47	181.00
IUUC-Dre-027879	Danio rerio	36.97	3.00e-39	154.00
IUUC-Dno-029335	Dasypus novemcinctus	32.35	4.00e-74	270.00
IUUC-Dor-030520	Dipodomys ordii	41.38	2.00e-33	135.00
IUUC-Dse-031566	Dothistroma septosporum	45.09	7.00e-59	220.00
IUUC-Dme-031838	Drosophila melanogaster	33.62	2.00e-69	255.00
IUUC-Eca-033563	Equus caballus	32.82	3.00e-75	274.00
IUUC-Fca-036052	Felis catus	33.33	5.00e-73	266.00
IUUC-Fal-037080	Ficedula albicollis	34.46	3.00e-74	270.00
IUUC-Fox-038022	Fusarium oxysporum	51.49	1.00e-61	229.00
IUUC-Fso-038115	Fusarium solani	50.50	1.00e-59	222.00
IUUC-Gmo-039461	Gadus morhua	30.59	8.00e-50	188.00
IUUC-Ggr-040100	Gaeumannomyces graminis	49.01	8.00e-57	213.00
IUUC-Gga-041133	Gallus gallus	33.55	1.00e-74	271.00
IUUC-Gac-041769	Gasterosteus aculeatus	37.85	4.00e-42	163.00
IUUC-Gma-043070	Glycine max	34.32	9.00e-68	249.00
IUUC-Ggo-044561	Gorilla gorilla	33.66	9.00e-76	275.00
IUUC-Hsa-046150	Homo sapiens	33.27	4.00e-76	276.00
IUUC-Hvu-047792	Hordeum vulgare	33.90	3.00e-39	153.00
IUUC-Itr-048630	Ictidomys tridecemlineatus	33.33	1.00e-72	265.00
IUUC-Kpa-049397	Komagataella pastoris	36.15	8.00e-71	258.00
IUUC-Lch-050365	Latimeria chalumnae	27.49	1.00e-39	155.00
IUUC-Lpe-050875	Leersia perrieri	34.64	4.00e-65	239.00
IUUC-Loc-052770	Lepisosteus oculatus	33.62	1.00e-70	258.00
IUUC-Lma-053291	Leptosphaeria maculans	37.92	2.00e-75	274.00
IUUC-Laf-053505	Loxodonta africana	33.08	7.00e-76	276.00
IUUC-Mcc-054803	Macaca mulatta	32.95	7.00e-76	276.00
IUUC-Meu-056578	Macropus eugenii	38.07	8.00e-39	152.00
IUUC-Mor-057211	Magnaporthe oryzae	48.02	8.00e-57	213.00
IUUC-Mpo-057411	Magnaporthe poae	49.51	6.00e-57	213.00
IUUC-Mtr-058066	Medicago truncatula	34.93	9.00e-66	242.00
IUUC-Mga-059735	Meleagris gallopavo	32.70	1.00e-74	271.00
IUUC-Mvi-060288	Microbotryum violaceum	32.47	8.00e-41	160.00
IUUC-Mmr-061343	Microcebus murinus	33.48	2.00e-73	268.00
IUUC-Mdo-062065	Monodelphis domestica	34.18	8.00e-75	272.00
IUUC-Mmu-063501	Mus musculus	34.18	2.00e-75	275.00
IUUC-Mac-064864	Musa acuminata	33.33	3.00e-63	233.00
IUUC-Mpu-066549	Mustela putorius furo	33.68	3.00e-73	267.00
IUUC-Mlu-067121	Myotis lucifugus	37.32	9.00e-42	162.00
IUUC-Nfi-068462	Neosartorya fischeri	37.90	3.00e-70	258.00
IUUC-Ncr-068838	Neurospora crassa	49.50	2.00e-59	222.00
IUUC-Nle-069854	Nomascus leucogenys	32.82	4.00e-76	276.00
IUUC-Opr-070803	Ochotona princeps	29.98	2.00e-67	248.00
IUUC-Ont-071642	Oreochromis niloticus	33.76	1.00e-72	265.00
IUUC-Oan-073675	Ornithorhynchus anatinus	35.10	4.00e-75	273.00
IUUC-Ocu-073863	Oryctolagus cuniculus	37.80	1.00e-41	161.00
IUUC-Oba-075682	Oryza barthii	34.13	7.00e-62	229.00
IUUC-Obr-076039	Oryza brachyantha	34.64	2.00e-65	241.00
IUUC-Ogu-078021	Oryza glumaepatula	34.78	2.00e-65	241.00
IUUC-Oin-079908	Oryza indica	29.11	5.00e-49	186.00
IUUC-Olo-081063	Oryza longistaminata	34.78	2.00e-65	241.00
IUUC-Ome-081930	Oryza meridionalis	33.27	5.00e-66	243.00
IUUC-Oni-082547	Oryza nivara	34.78	1.00e-65	241.00
IUUC-Opu-084089	Oryza punctata	34.78	2.00e-64	238.00
IUUC-Oru-084844	Oryza rufipogon	34.78	2.00e-65	241.00
IUUC-Osa-085582	Oryza sativa	34.78	2.00e-65	241.00
IUUC-Ola-087187	Oryzias latipes	33.97	2.00e-74	271.00
IUUC-Olu-087792	Ostreococcus lucimarinus	29.13	3.00e-57	213.00
IUUC-Oga-088390	Otolemur garnettii	33.07	2.00e-74	271.00
IUUC-Oar-089740	Ovis aries	32.62	1.00e-68	251.00
IUUC-Ptr-091581	Pan troglodytes	33.01	3.00e-76	277.00
IUUC-Pan-092258	Papio anubis	29.06	6.00e-60	223.00
IUUC-Psi-093761	Pelodiscus sinensis	31.97	3.00e-70	257.00
IUUC-Pno-094957	Phaeosphaeria nodorum	37.97	1.00e-45	175.00
IUUC-Ppa-095428	Physcomitrella patens	34.49	1.00e-69	255.00
IUUC-Pfo-097357	Poecilia formosa	34.62	3.00e-75	274.00
IUUC-Pab-098520	Pongo abelii	33.01	5.00e-76	276.00
IUUC-Pop-099331	Populus trichocarpa	32.39	3.00e-64	237.00
IUUC-Ppe-101548	Prunus persica	33.84	4.00e-65	240.00
IUUC-Pva-103243	Pteropus vampyrus	34.01	2.00e-67	247.00
IUUC-Pgr-103591	Puccinia graminis	30.55	4.00e-36	144.00
IUUC-Ptt-103782	Puccinia triticina	37.60	3.00e-22	97.40
IUUC-Pte-104247	Pyrenophora teres	47.09	1.00e-59	222.00
IUUC-Pyt-104641	Pyrenophora triticirepentis	47.09	1.00e-59	222.00
IUUC-Rno-105202	Rattus norvegicus	34.18	2.00e-75	274.00
IUUC-Sce-106250	Saccharomyces cerevisiae	29.70	9.00e-54	202.00
IUUC-Sha-107036	Sarcophilus harrisii	33.08	2.00e-75	274.00
IUUC-Sja-107912	Schizosaccharomyces japonicus	45.79	6.00e-129	452.00
IUUC-Ssl-108607	Sclerotinia sclerotiorum	47.41	1.00e-60	226.00
IUUC-Sit-109838	Setaria italica	35.42	1.00e-67	248.00
IUUC-Sly-110872	Solanum lycopersicum	34.11	6.00e-66	242.00
IUUC-Stu-111933	Solanum tuberosum	33.89	7.00e-67	245.00
IUUC-Sbi-114587	Sorghum bicolor	34.99	3.00e-68	250.00
IUUC-Sre-115093	Sporisorium reilianum	36.92	1.00e-39	156.00
IUUC-Ssc-115462	Sus scrofa	32.23	2.00e-74	271.00
IUUC-Tgu-117186	Taeniopygia guttata	34.25	1.00e-72	265.00
IUUC-Tru-118310	Takifugu rubripes	34.33	9.00e-76	275.00
IUUC-Tsy-118927	Tarsius syrichta	37.14	5.00e-27	113.00
IUUC-Tni-120832	Tetraodon nigroviridis	34.75	4.00e-74	270.00
IUUC-Tca-121584	Theobroma cacao	30.54	3.00e-63	234.00
IUUC-Tre-122140	Trichoderma reesei	45.09	7.00e-59	219.00
IUUC-Tvi-122663	Trichoderma virens	50.00	3.00e-59	221.00
IUUC-Tae-123476	Triticum aestivum	35.95	2.00e-66	244.00
IUUC-Tur-126239	Triticum urartu	35.95	1.00e-66	245.00
IUUC-Tme-127108	Tuber melanosporum	36.40	1.00e-60	225.00
IUUC-Ttr-129010	Tursiops truncatus	33.69	3.00e-73	267.00
IUUC-Uma-129499	Ustilago maydis	32.63	4.00e-41	161.00
IUUC-Vda-129825	Verticillium dahliae	47.76	9.00e-57	213.00
IUUC-Vpa-130374	Vicugna pacos	36.42	4.00e-29	120.00
IUUC-Vvi-131136	Vitis vinifera	34.20	2.00e-64	237.00
IUUC-Xtr-132141	Xenopus tropicalis	35.21	6.00e-78	282.00
IUUC-Xma-133980	Xiphophorus maculatus	33.98	1.00e-73	268.00
IUUC-Yli-134457	Yarrowia lipolytica	33.90	1.00e-72	265.00
IUUC-Zma-135321	Zea mays	34.35	6.00e-68	249.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence