iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132108

Ensembl Protein ID

ENSXETP00000037030.2

UniProt Accession

F7EDP6; F7EDP6_XENTR

Genbank Protein ID

ENSXETP00000037030

Protein Name

Mitogen-activated protein kinase kinase kinase 10

Genbank Nucleotide ID

AAMC01084878

Gene Name

map3k10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000016998.3	ENSXETT00000037030.2	ENSXETP00000037030.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-14	53.8	38	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvi...ekeeqdegWlkgvkelegkrGlfPenFve 60
            + +dyea+ ++eLtl++Gd v+++   +  + degW+ g  + + k G+fP+n+v+
   Q: 38   MAVFDYEATAEEELTLHRGDLVEILskdSTVSGDEGWWTG--KIKDKVGIFPSNYVV 92
           589**********************66666678*******..8************97 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MDGPQKNEGF LWQSSKDNKE NGVWNEVQSY GVSNPLWMAV FDYEATAEEE LTLHRGDLVE 60
ILSKDSTVSG DEGWWTGKIK DKVGIFPSNY VVSDNKYTTL TGAPKQCPLP LEIEFEELNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGGTC CTCAGAAAAA TGAGGGCTTT TTATGGCAGA GCTCGAAAGA CAATAAAGAA 60
AATGGGGTGT GGAATGAGGT GCAGAGTTAT GGGGTCTCTA ATCCATTATG GATGGCAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR016231--MLK1/MLK2/MLK4
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0007257--P:activation of JUN kinase activity
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002478	Amborella trichopoda	30.34	2.00e-22	100.00
IUUC-Aca-004768	Anolis carolinensis	76.20	0.00e+00	893.00
IUUC-Aly-006459	Arabidopsis lyrata	31.78	3.00e-23	103.00
IUUC-Ath-006581	Arabidopsis thaliana	31.78	5.00e-23	102.00
IUUC-Ame-011769	Astyanax mexicanus	58.51	0.00e+00	808.00
IUUC-Bdi-014195	Brachypodium distachyon	33.62	4.00e-24	106.00
IUUC-Bol-015857	Brassica oleracea	32.35	2.00e-25	110.00
IUUC-Bra-017825	Brassica rapa	34.25	2.00e-24	107.00
IUUC-Cja-019696	Callithrix jacchus	59.79	0.00e+00	846.00
IUUC-Cfa-020789	Canis familiaris	57.35	3.00e-175	608.00
IUUC-Csa-024243	Chlorocebus sabaeus	58.90	0.00e+00	866.00
IUUC-Cho-024961	Choloepus hoffmanni	66.51	1.00e-80	293.00
IUUC-Csv-026102	Ciona savignyi	60.75	2.00e-158	552.00
IUUC-Dre-028573	Danio rerio	77.14	0.00e+00	840.00
IUUC-Dno-029095	Dasypus novemcinctus	70.72	0.00e+00	754.00
IUUC-Dor-030866	Dipodomys ordii	59.57	3.00e-173	602.00
IUUC-Dme-032210	Drosophila melanogaster	49.32	2.00e-140	493.00
IUUC-Eca-033782	Equus caballus	68.87	5.00e-119	421.00
IUUC-Fca-036250	Felis catus	72.50	0.00e+00	773.00
IUUC-Gmo-038497	Gadus morhua	76.41	0.00e+00	816.00
IUUC-Gac-042509	Gasterosteus aculeatus	70.28	0.00e+00	833.00
IUUC-Gma-043059	Glycine max	34.91	5.00e-24	106.00
IUUC-Ggo-045471	Gorilla gorilla	69.12	0.00e+00	696.00
IUUC-Hsa-046936	Homo sapiens	59.85	0.00e+00	870.00
IUUC-Hvu-047818	Hordeum vulgare	33.78	3.00e-23	103.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	73.33	0.00e+00	772.00
IUUC-Lch-049935	Latimeria chalumnae	70.66	0.00e+00	1133.00
IUUC-Loc-052286	Lepisosteus oculatus	76.47	0.00e+00	855.00
IUUC-Mcc-055733	Macaca mulatta	57.26	0.00e+00	866.00
IUUC-Mtr-057869	Medicago truncatula	33.04	2.00e-24	107.00
IUUC-Mdo-062516	Monodelphis domestica	60.97	0.00e+00	907.00
IUUC-Mmu-064082	Mus musculus	62.43	0.00e+00	937.00
IUUC-Mac-065156	Musa acuminata	35.58	4.00e-23	103.00
IUUC-Mpu-065934	Mustela putorius furo	60.92	0.00e+00	890.00
IUUC-Opr-070869	Ochotona princeps	72.73	4.00e-159	555.00
IUUC-Ont-072492	Oreochromis niloticus	69.27	0.00e+00	867.00
IUUC-Ocu-074350	Oryctolagus cuniculus	71.62	0.00e+00	767.00
IUUC-Oba-075998	Oryza barthii	34.42	7.00e-24	105.00
IUUC-Obr-076837	Oryza brachyantha	36.89	1.00e-26	114.00
IUUC-Ogl-077452	Oryza glaberrima	34.42	1.00e-23	105.00
IUUC-Ogu-078147	Oryza glumaepatula	34.42	9.00e-24	105.00
IUUC-Oin-079983	Oryza indica	34.42	8.00e-24	105.00
IUUC-Olo-080886	Oryza longistaminata	34.67	3.00e-24	106.00
IUUC-Ome-081788	Oryza meridionalis	31.97	5.00e-30	125.00
IUUC-Oni-082859	Oryza nivara	34.42	1.00e-23	105.00
IUUC-Opu-083900	Oryza punctata	34.22	3.00e-24	107.00
IUUC-Oru-085212	Oryza rufipogon	34.67	6.00e-24	105.00
IUUC-Osa-085517	Oryza sativa	34.42	1.00e-23	105.00
IUUC-Ola-087224	Oryzias latipes	61.12	0.00e+00	908.00
IUUC-Oga-088351	Otolemur garnettii	60.96	0.00e+00	905.00
IUUC-Oar-089467	Ovis aries	59.82	8.00e-175	607.00
IUUC-Ptr-091607	Pan troglodytes	59.75	0.00e+00	868.00
IUUC-Psi-093760	Pelodiscus sinensis	53.56	0.00e+00	666.00
IUUC-Pma-094398	Petromyzon marinus	68.17	0.00e+00	655.00
IUUC-Pfo-096104	Poecilia formosa	64.53	0.00e+00	885.00
IUUC-Ppe-101625	Prunus persica	35.27	2.00e-24	107.00
IUUC-Rno-105688	Rattus norvegicus	62.60	0.00e+00	955.00
IUUC-Sha-107470	Sarcophilus harrisii	54.50	9.00e-163	567.00
IUUC-Smo-109661	Selaginella moellendorffii	32.99	4.00e-25	108.00
IUUC-Sit-110451	Setaria italica	33.63	6.00e-24	105.00
IUUC-Sly-111528	Solanum lycopersicum	29.41	5.00e-23	103.00
IUUC-Sbi-114009	Sorghum bicolor	34.38	6.00e-24	105.00
IUUC-Ssc-115332	Sus scrofa	74.21	0.00e+00	783.00
IUUC-Tru-117692	Takifugu rubripes	68.19	0.00e+00	862.00
IUUC-Tsy-119412	Tarsius syrichta	87.04	2.00e-54	206.00
IUUC-Tni-120689	Tetraodon nigroviridis	67.46	0.00e+00	841.00
IUUC-Tca-121565	Theobroma cacao	33.33	6.00e-24	105.00
IUUC-Tur-126322	Triticum urartu	33.33	2.00e-24	107.00
IUUC-Ttr-128550	Tursiops truncatus	61.31	0.00e+00	916.00
IUUC-Xma-134254	Xiphophorus maculatus	64.56	0.00e+00	899.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence