iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107982

Ensembl Protein ID

EEB05854

UniProt Accession

B6JWV3; B6JWV3_SCHJY

Genbank Protein ID

EEB05854.1

Protein Name

NEDD8 activating enzyme

Genbank Nucleotide ID

KE651166

Gene Name

SJAG_00878

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_00878	EEB05854	EEB05854

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.90e-83	277.9	23	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 10   eeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkf 110
           eea ++++++k+l+vGagglGcE+l nL+ +G++si vvDmdt++++nlnrqFLfr++dvg++KA++aaea++++ p+++v++  ++++++ ++   + ++
   Q: 23   EEATKAIQTTKILVVGAGGLGCEILVNLACLGFESIDVVDMDTIDLTNLNRQFLFRKKDVGQPKAQIAAEAIQRRMPNCRVTPIVSKVQDIPMD--QLYTY 121
           58899*****************************************************************************************..7999* PP
   S: 111  dvVvlaldnrearrkvnrlclna........rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpnaaehtiewavlfnklleeea 201
            +V+++ld++earr+vn  ++++         + li++g++G+ Gq+rvi++ +t cy+cs    p +kt+P+ct+++ p+  eh++ewa     ++ +++
   Q: 122  GLVICGLDSVEARRWVNATLVSMvddddpqsLKALIDGGCEGFRGQARVILPTITSCYECSLdmLPSKKTYPICTIANKPRLLEHCVEWA-----YVLQWQ 217
           **************************************************************89999***********************.....555555 PP
   S: 202  geeevlek 209
           +e+ ++++
   Q: 218  AEQGEKDP 225
           55555444 PP

Organism

Schizosaccharomyces japonicus

Protein Sequence
(Fasta)

MALSHLRKLL NNPGPFADAY DPEEATKAIQ TTKILVVGAG GLGCEILVNL ACLGFESIDV 60
VDMDTIDLTN LNRQFLFRKK DVGQPKAQIA AEAIQRRMPN CRVTPIVSKV QDIPMDQLYT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTGGTCTA AGGTTTTGTC AGAACGTAAT TTGTTAATTC TTTTAGTTTC TTTTCCATTC 60
ACTCCATGAA TACCACTGTG CACCACTGTG CAATCTTTCT TGTGAGTGCA TGTTTAATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	40.00	5.00e-66	242.00
IUUC-Aml-001578	Ailuropoda melanoleuca	43.95	2.00e-102	363.00
IUUC-Atr-002591	Amborella trichopoda	41.18	4.00e-71	259.00
IUUC-Apl-003671	Anas platyrhynchos	43.02	1.00e-101	361.00
IUUC-Aca-004749	Anolis carolinensis	43.02	3.00e-100	357.00
IUUC-Aly-005747	Arabidopsis lyrata	42.41	6.00e-82	295.00
IUUC-Ath-006623	Arabidopsis thaliana	41.36	5.00e-80	289.00
IUUC-Ago-007934	Ashbya gossypii	43.37	8.00e-64	234.00
IUUC-Acl-008047	Aspergillus clavatus	47.87	4.00e-115	405.00
IUUC-Afl-008615	Aspergillus flavus	40.90	3.00e-75	273.00
IUUC-Afu-008996	Aspergillus fumigatus	48.34	5.00e-108	382.00
IUUC-Ani-009281	Aspergillus nidulans	42.52	1.00e-82	298.00
IUUC-Ang-009539	Aspergillus niger	49.53	4.00e-108	382.00
IUUC-Aor-010151	Aspergillus oryzae	47.03	6.00e-104	369.00
IUUC-Ate-010502	Aspergillus terreus	49.64	8.00e-108	381.00
IUUC-Ame-011837	Astyanax mexicanus	43.49	8.00e-91	325.00
IUUC-Bgr-012068	Blumeria graminis	45.52	3.00e-99	353.00
IUUC-Bta-013003	Bos taurus	43.95	4.00e-103	365.00
IUUC-Bci-013983	Botrytis cinerea	48.96	4.00e-105	372.00
IUUC-Bdi-014429	Brachypodium distachyon	39.89	3.00e-70	256.00
IUUC-Bol-015490	Brassica oleracea	41.53	5.00e-76	276.00
IUUC-Bra-018023	Brassica rapa	41.26	6.00e-75	272.00
IUUC-Cel-018684	Caenorhabditis elegans	41.32	2.00e-90	323.00
IUUC-Cja-019200	Callithrix jacchus	43.39	3.00e-101	360.00
IUUC-Cfa-021038	Canis familiaris	43.72	1.00e-102	364.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	44.10	2.00e-89	320.00
IUUC-Csa-024079	Chlorocebus sabaeus	43.95	7.00e-103	365.00
IUUC-Cho-025052	Choloepus hoffmanni	39.07	1.00e-85	308.00
IUUC-Cin-025113	Ciona intestinalis	41.63	2.00e-87	314.00
IUUC-Csv-026231	Ciona savignyi	41.82	6.00e-92	328.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	46.88	6.00e-98	348.00
IUUC-Cne-026850	Cryptococcus neoformans	48.93	4.00e-108	382.00
IUUC-Cme-027275	Cyanidioschyzon merolae	35.95	2.00e-61	228.00
IUUC-Dre-028751	Danio rerio	44.06	1.00e-90	325.00
IUUC-Dno-029571	Dasypus novemcinctus	43.26	5.00e-101	359.00
IUUC-Dor-030395	Dipodomys ordii	44.98	3.00e-103	366.00
IUUC-Dse-031329	Dothistroma septosporum	45.23	4.00e-102	362.00
IUUC-Dme-031776	Drosophila melanogaster	43.81	8.00e-93	332.00
IUUC-Ete-032894	Echinops telfairi	46.01	1.00e-36	145.00
IUUC-Eca-034389	Equus caballus	43.72	1.00e-102	364.00
IUUC-Eeu-035152	Erinaceus europaeus	40.15	9.00e-80	288.00
IUUC-Fca-036032	Felis catus	43.72	7.00e-103	365.00
IUUC-Fal-037506	Ficedula albicollis	43.49	2.00e-101	360.00
IUUC-Fox-037871	Fusarium oxysporum	47.37	2.00e-88	317.00
IUUC-Fso-038350	Fusarium solani	47.93	7.00e-101	358.00
IUUC-Gmo-039647	Gadus morhua	44.58	4.00e-92	329.00
IUUC-Ggr-039859	Gaeumannomyces graminis	49.65	6.00e-106	375.00
IUUC-Gga-040843	Gallus gallus	42.33	5.00e-97	345.00
IUUC-Gac-042610	Gasterosteus aculeatus	44.06	9.00e-92	328.00
IUUC-Gma-043031	Glycine max	42.02	2.00e-75	274.00
IUUC-Ggo-044788	Gorilla gorilla	43.62	2.00e-101	360.00
IUUC-Hsa-045849	Homo sapiens	43.72	8.00e-103	365.00
IUUC-Hvu-047819	Hordeum vulgare	42.01	8.00e-63	231.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	43.49	7.00e-102	362.00
IUUC-Kpa-049393	Komagataella pastoris	55.65	4.00e-105	372.00
IUUC-Lch-049471	Latimeria chalumnae	42.99	2.00e-90	323.00
IUUC-Lpe-051297	Leersia perrieri	39.62	2.00e-79	287.00
IUUC-Loc-052910	Lepisosteus oculatus	43.49	1.00e-92	331.00
IUUC-Lma-053181	Leptosphaeria maculans	48.36	7.00e-110	388.00
IUUC-Laf-054314	Loxodonta africana	43.45	4.00e-101	359.00
IUUC-Mcc-054870	Macaca mulatta	43.72	7.00e-103	365.00
IUUC-Meu-056574	Macropus eugenii	37.74	7.00e-48	182.00
IUUC-Mor-056919	Magnaporthe oryzae	47.52	7.00e-102	362.00
IUUC-Mpo-057614	Magnaporthe poae	48.48	2.00e-102	363.00
IUUC-Mtr-058110	Medicago truncatula	41.46	2.00e-74	271.00
IUUC-Mla-058949	Melampsora laricipopulina	52.62	2.00e-110	390.00
IUUC-Mga-059455	Meleagris gallopavo	43.02	8.00e-101	358.00
IUUC-Mvi-060270	Microbotryum violaceum	51.97	4.00e-113	399.00
IUUC-Mmr-061155	Microcebus murinus	43.50	6.00e-100	355.00
IUUC-Mdo-062037	Monodelphis domestica	44.24	3.00e-102	363.00
IUUC-Mmu-063670	Mus musculus	43.72	2.00e-102	364.00
IUUC-Mac-064711	Musa acuminata	40.90	8.00e-71	258.00
IUUC-Mpu-066734	Mustela putorius furo	43.49	2.00e-101	360.00
IUUC-Mlu-067068	Myotis lucifugus	43.49	5.00e-102	362.00
IUUC-Nfi-068349	Neosartorya fischeri	48.34	3.00e-108	383.00
IUUC-Ncr-068626	Neurospora crassa	49.00	9.00e-100	354.00
IUUC-Nle-069366	Nomascus leucogenys	49.25	7.00e-98	348.00
IUUC-Ont-072196	Oreochromis niloticus	44.42	8.00e-91	325.00
IUUC-Oan-073511	Ornithorhynchus anatinus	44.42	1.00e-102	364.00
IUUC-Ocu-073773	Oryctolagus cuniculus	44.19	3.00e-103	366.00
IUUC-Oba-075726	Oryza barthii	35.81	2.00e-70	257.00
IUUC-Obr-076286	Oryza brachyantha	39.35	1.00e-79	288.00
IUUC-Ogu-078473	Oryza glumaepatula	35.81	2.00e-70	257.00
IUUC-Oin-079393	Oryza indica	39.89	8.00e-81	291.00
IUUC-Olo-080446	Oryza longistaminata	37.74	1.00e-73	268.00
IUUC-Ome-081737	Oryza meridionalis	37.47	2.00e-73	267.00
IUUC-Oni-082853	Oryza nivara	35.81	2.00e-70	257.00
IUUC-Opu-083590	Oryza punctata	40.16	9.00e-81	291.00
IUUC-Oru-084184	Oryza rufipogon	35.81	2.00e-70	257.00
IUUC-Osa-085402	Oryza sativa	39.89	8.00e-81	291.00
IUUC-Ola-086671	Oryzias latipes	49.70	5.00e-81	292.00
IUUC-Olu-087738	Ostreococcus lucimarinus	42.20	6.00e-70	255.00
IUUC-Oga-088101	Otolemur garnettii	43.95	2.00e-102	363.00
IUUC-Oar-090293	Ovis aries	43.45	2.00e-101	360.00
IUUC-Ptr-090503	Pan troglodytes	43.72	8.00e-103	365.00
IUUC-Pan-092477	Papio anubis	42.59	2.00e-96	343.00
IUUC-Psi-093442	Pelodiscus sinensis	43.55	7.00e-100	355.00
IUUC-Pma-094247	Petromyzon marinus	42.73	9.00e-92	328.00
IUUC-Pno-094780	Phaeosphaeria nodorum	48.66	6.00e-111	391.00
IUUC-Ppa-095961	Physcomitrella patens	41.42	2.00e-87	314.00
IUUC-Pfo-096846	Poecilia formosa	45.18	4.00e-92	329.00
IUUC-Pab-098060	Pongo abelii	43.49	6.00e-94	335.00
IUUC-Pop-099914	Populus trichocarpa	43.09	8.00e-81	291.00
IUUC-Pca-100500	Procavia capensis	39.60	4.00e-73	266.00
IUUC-Ppe-102008	Prunus persica	41.74	8.00e-74	268.00
IUUC-Pva-103095	Pteropus vampyrus	52.08	4.00e-56	209.00
IUUC-Pgr-103666	Puccinia graminis	51.40	3.00e-113	399.00
IUUC-Ptt-103901	Puccinia triticina	52.31	3.00e-116	410.00
IUUC-Pte-104198	Pyrenophora teres	48.37	5.00e-110	389.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	47.66	3.00e-107	379.00
IUUC-Rno-105446	Rattus norvegicus	43.72	1.00e-102	364.00
IUUC-Sce-106355	Saccharomyces cerevisiae	42.48	1.00e-67	247.00
IUUC-Sha-106664	Sarcophilus harrisii	44.24	5.00e-102	362.00
IUUC-Spo-108345	Schizosaccharomyces pombe	50.12	5.00e-119	419.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	46.21	4.00e-90	323.00
IUUC-Smo-109133	Selaginella moellendorffii	46.02	2.00e-98	350.00
IUUC-Sit-109724	Setaria italica	38.81	2.00e-70	258.00
IUUC-Sly-110916	Solanum lycopersicum	42.29	2.00e-81	293.00
IUUC-Stu-112236	Solanum tuberosum	42.55	3.00e-82	296.00
IUUC-Sar-113044	Sorex araneus	44.39	4.00e-99	352.00
IUUC-Sbi-114276	Sorghum bicolor	39.35	3.00e-70	257.00
IUUC-Sre-114963	Sporisorium reilianum	54.12	9.00e-122	427.00
IUUC-Ssc-116301	Sus scrofa	43.22	4.00e-101	359.00
IUUC-Tgu-117265	Taeniopygia guttata	43.49	1.00e-101	361.00
IUUC-Tru-117526	Takifugu rubripes	44.32	2.00e-90	324.00
IUUC-Tsy-119483	Tarsius syrichta	44.55	5.00e-100	355.00
IUUC-Tni-120363	Tetraodon nigroviridis	44.42	6.00e-93	332.00
IUUC-Tca-121731	Theobroma cacao	40.56	1.00e-72	265.00
IUUC-Tre-122221	Trichoderma reesei	47.89	8.00e-90	321.00
IUUC-Tvi-122352	Trichoderma virens	46.51	1.00e-100	357.00
IUUC-Tae-123864	Triticum aestivum	40.11	2.00e-69	254.00
IUUC-Tur-126070	Triticum urartu	37.69	1.00e-56	211.00
IUUC-Tme-127199	Tuber melanosporum	52.74	4.00e-107	379.00
IUUC-Tbe-128076	Tupaia belangeri	43.95	6.00e-103	365.00
IUUC-Ttr-128695	Tursiops truncatus	53.52	6.00e-41	159.00
IUUC-Uma-129638	Ustilago maydis	53.41	2.00e-121	426.00
IUUC-Vda-129963	Verticillium dahliae	47.92	4.00e-92	329.00
IUUC-Vpa-130637	Vicugna pacos	39.16	2.00e-85	306.00
IUUC-Vvi-131613	Vitis vinifera	40.61	6.00e-74	269.00
IUUC-Xtr-132924	Xenopus tropicalis	45.02	8.00e-91	325.00
IUUC-Xma-134209	Xiphophorus maculatus	45.28	2.00e-93	333.00
IUUC-Yli-134365	Yarrowia lipolytica	50.84	4.00e-106	376.00
IUUC-Zma-135941	Zea mays	35.68	3.00e-65	240.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence