iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045050

UUCD1 version

UUC-GoG-00812

Ensembl Protein ID

ENSGGOP00000021616.1

UniProt Accession

G3S0M1; G3S0M1_GORGO

Protein Name

Uncharacterized protein

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000013326.2	ENSGGOT00000013378.2	ENSGGOP00000013003.2
ENSGGOG00000013326.2	ENSGGOT00000028329.1	ENSGGOP00000021616.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	94.53	0.00e+00	2082.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	27.57	1.00e-34	143.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

LGHSHFTGCH WTCQVPESCD NGLHCAGPLG HLHRRCQRTS AHLLVFTEHA EMRRFKRKHL 60
TAIDCQHLAR SHLAVTQPFG QRWTNRDPNH GLYPKPRTKR GSRGQGRQRC IPEFFLAGKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTACG AGGTGACTTC AGGTGAGTCC TCTCTCAGCC CCAGCTTAAT CATGGTACAA 60
CTGTAGGATT GCTTTGAGGG TCAGACGAGA ATATAGGAAA GAACTGCAAA AGCTGTAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	43.48	1.00e-03	39.70
IUUC-Aml-001396	Ailuropoda melanoleuca	87.93	0.00e+00	1864.00
IUUC-Apl-003317	Anas platyrhynchos	47.00	0.00e+00	898.00
IUUC-Aca-004498	Anolis carolinensis	51.64	0.00e+00	892.00
IUUC-Ath-007293	Arabidopsis thaliana	24.48	4.00e-03	37.40
IUUC-Ani-009226	Aspergillus nidulans	36.73	6.00e-02	33.50
IUUC-Ate-010526	Aspergillus terreus	24.72	1.00e-03	38.90
IUUC-Ame-011808	Astyanax mexicanus	52.41	1.00e-114	405.00
IUUC-Bta-013250	Bos taurus	85.57	0.00e+00	1812.00
IUUC-Cja-019638	Callithrix jacchus	93.73	0.00e+00	2033.00
IUUC-Cfa-020195	Canis familiaris	89.07	0.00e+00	1785.00
IUUC-Cpo-022269	Cavia porcellus	83.46	0.00e+00	1740.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	3.00e-08	54.30
IUUC-Csa-024060	Chlorocebus sabaeus	94.27	0.00e+00	1790.00
IUUC-Cho-025003	Choloepus hoffmanni	89.39	0.00e+00	725.00
IUUC-Cin-025694	Ciona intestinalis	28.57	7.00e-32	131.00
IUUC-Dre-028083	Danio rerio	47.10	0.00e+00	789.00
IUUC-Dno-029203	Dasypus novemcinctus	84.54	0.00e+00	1714.00
IUUC-Dor-030477	Dipodomys ordii	80.04	0.00e+00	803.00
IUUC-Ete-032861	Echinops telfairi	85.28	0.00e+00	1791.00
IUUC-Eca-033205	Equus caballus	88.79	0.00e+00	1922.00
IUUC-Eeu-034784	Erinaceus europaeus	80.70	0.00e+00	1126.00
IUUC-Fca-035797	Felis catus	87.57	0.00e+00	1880.00
IUUC-Gmo-038855	Gadus morhua	46.17	2.00e-125	443.00
IUUC-Gga-040326	Gallus gallus	49.09	0.00e+00	927.00
IUUC-Gac-042240	Gasterosteus aculeatus	40.38	0.00e+00	694.00
IUUC-Hsa-046650	Homo sapiens	94.62	0.00e+00	2086.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	87.56	0.00e+00	690.00
IUUC-Lch-050231	Latimeria chalumnae	42.93	3.00e-170	592.00
IUUC-Loc-051884	Lepisosteus oculatus	46.98	0.00e+00	917.00
IUUC-Lma-053267	Leptosphaeria maculans	22.53	1.00e-04	42.40
IUUC-Laf-053843	Loxodonta africana	87.94	0.00e+00	1874.00
IUUC-Mcc-055570	Macaca mulatta	92.98	0.00e+00	2046.00
IUUC-Meu-056798	Macropus eugenii	67.68	1.00e-153	537.00
IUUC-Mla-058841	Melampsora laricipopulina	34.55	2.40e-02	32.00
IUUC-Mga-059648	Meleagris gallopavo	49.59	0.00e+00	891.00
IUUC-Mmr-060757	Microcebus murinus	86.94	0.00e+00	1844.00
IUUC-Mdo-061913	Monodelphis domestica	66.70	0.00e+00	1308.00
IUUC-Mmu-064337	Mus musculus	86.42	0.00e+00	1858.00
IUUC-Mpu-066483	Mustela putorius furo	86.50	0.00e+00	1867.00
IUUC-Mlu-068204	Myotis lucifugus	84.86	0.00e+00	1824.00
IUUC-Ncr-068735	Neurospora crassa	25.51	4.90e-01	30.40
IUUC-Nle-070053	Nomascus leucogenys	94.65	0.00e+00	2058.00
IUUC-Opr-070588	Ochotona princeps	80.49	0.00e+00	1730.00
IUUC-Ont-072655	Oreochromis niloticus	44.60	0.00e+00	703.00
IUUC-Oan-073351	Ornithorhynchus anatinus	59.87	0.00e+00	1251.00
IUUC-Ocu-074465	Oryctolagus cuniculus	87.19	0.00e+00	1786.00
IUUC-Opu-083155	Oryza punctata	46.34	3.00e-03	37.40
IUUC-Olu-087831	Ostreococcus lucimarinus	30.72	3.00e-58	221.00
IUUC-Oga-089088	Otolemur garnettii	87.93	0.00e+00	1823.00
IUUC-Oar-089870	Ovis aries	84.43	0.00e+00	1758.00
IUUC-Ptr-090957	Pan troglodytes	95.67	0.00e+00	2064.00
IUUC-Pan-092632	Papio anubis	95.06	0.00e+00	1957.00
IUUC-Psi-093035	Pelodiscus sinensis	52.98	0.00e+00	1074.00
IUUC-Pno-094870	Phaeosphaeria nodorum	25.27	4.00e-05	43.90
IUUC-Pfo-096902	Poecilia formosa	42.39	0.00e+00	649.00
IUUC-Pab-098206	Pongo abelii	94.58	0.00e+00	1840.00
IUUC-Pop-100065	Populus trichocarpa	37.50	1.20e-02	34.30
IUUC-Pca-100238	Procavia capensis	80.58	0.00e+00	1758.00
IUUC-Pva-103182	Pteropus vampyrus	83.35	0.00e+00	1789.00
IUUC-Pte-104033	Pyrenophora teres	24.29	2.00e-04	42.00
IUUC-Pyt-104599	Pyrenophora triticirepentis	24.29	1.00e-04	42.00
IUUC-Rno-105141	Rattus norvegicus	86.04	0.00e+00	1852.00
IUUC-Sce-106341	Saccharomyces cerevisiae	25.76	2.00e-03	37.70
IUUC-Sha-106827	Sarcophilus harrisii	65.34	0.00e+00	1377.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	27.60	3.00e-36	147.00
IUUC-Spo-108147	Schizosaccharomyces pombe	27.57	5.00e-35	143.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	24.24	6.00e-04	40.00
IUUC-Sre-115025	Sporisorium reilianum	34.39	6.00e-39	156.00
IUUC-Ssc-116188	Sus scrofa	88.57	0.00e+00	1189.00
IUUC-Tgu-116612	Taeniopygia guttata	58.00	8.00e-164	570.00
IUUC-Tsy-119560	Tarsius syrichta	83.47	3.00e-117	416.00
IUUC-Tni-120734	Tetraodon nigroviridis	44.00	0.00e+00	670.00
IUUC-Tre-122089	Trichoderma reesei	40.74	2.00e-04	41.20
IUUC-Tae-125126	Triticum aestivum	36.23	7.00e-04	38.10
IUUC-Tme-127009	Tuber melanosporum	23.10	2.00e-04	41.60
IUUC-Tbe-127431	Tupaia belangeri	86.34	0.00e+00	1618.00
IUUC-Ttr-128744	Tursiops truncatus	82.01	0.00e+00	1760.00
IUUC-Uma-129536	Ustilago maydis	34.78	3.00e-40	160.00
IUUC-Vpa-130123	Vicugna pacos	69.13	1.00e-108	387.00
IUUC-Xtr-132902	Xenopus tropicalis	56.00	0.00e+00	962.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence