iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093911

Ensembl Protein ID

ENSPSIP00000004399.1

UniProt Accession

K7F8N9; K7F8N9_PELSI

Genbank Protein ID

ENSPSIP00000004399

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01068429

Gene Name

WDR48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000004103.1	ENSPSIT00000004422.1	ENSPSIP00000004399.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-33	111.8	208	245
UBD/Beta-Prp	1.80e-47	162.0	31	294
ULD/UDP/UFD/RAWUL	1.20e-23	83.4	573	678
ULD/UBL/SUMO	5.70e-59	196.9	564	671

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHtd v +l +  d t  +sGs Dgti++W+l +++++
   Q: 208  GHTDNVKALLLnRDgTQCLSGSSDGTIRLWSLGQQRCI 245
           8********88*888*****************999997 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkl...lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           + +++++  p  + l+t++rd+ i++w+v + k    ++s++ h++ v+++ +  +gk+l+++s+D t+kvw+  +g c++tl+ h+d+
   Q: 31   NGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQdpyIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDY 119
           55677888889999*****************999999**************************************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           v +l++ ++++ ++s++ dr i +wd++t + l +         lsg+++++ ++++++ g ++vsGs+ +++r+Wd +t   l +l+g
   Q: 120  VKALAYAKDKELVASAGLDRQIFLWDVNTLTALTAsnntvttsSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLMKLKG 208
           *********************************999********************************************999999*99 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            htd v+ l ++++g++++sgs dgt++lw+l +++c+ t++ h++ v+ +++ +  ++++sg+ D+ i++ dlr+ d+   +  ++
   Q: 209  -HTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEK 294
           .************************************************************************99988766665555 PP

ULD/UDP/UFD/RAWUL

   S: 4    sLeplesnkakddsklkkkylrcsarltVkhlkkflaeklkl........sssy.....................evdllcedevLedn 63
            L+p++s++ak+   lkk++l++s++l+V++++++++ek+++        s                        +++llc+d+vL++n
   Q: 573  YLQPHSSSGAKT---LKKDRLSASDMLQVRKVMEHVYEKIINldnesqttS--SsnnektgeqekeediavlaeeKIELLCQDQVLDPN 656
           69**********...*************************99988766653..045799999999************************ PP
   S: 64   etLeeikyifiwkkegpLvLqYr 86
           ++L+++ ++fiwk++g+L+L+Yr
   Q: 657  MDLRTV-KHFIWKSGGDLTLHYR 678
           ******.***************9 PP

ULD/UBL/SUMO

   S: 1    eskffkapvslkvagqdGsevlfklklsa....qlkklmeavYvkrinldensvrfv.fngqkireqetpeelevededkiellcq... 81
           ++kf+k+p++l++++++G+++l+k++lsa    q++k+me+vY+k+inld++s++++ +n++k +eqe++e+++v++e+kiellcq   
   Q: 564  MPKFNKIPFYLQPHSSSGAKTLKKDRLSAsdmlQVRKVMEHVYEKIINLDNESQTTSsSNNEKTGEQEKEEDIAVLAEEKIELLCQdqv 652
           8********************************************************9****************************777 PP
   S: 82   ...............ksGG 85
                          ksGG
   Q: 653  ldpnmdlrtvkhfiwKSGG 671
           7777777777777777776 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MAAHHRQNAA GRRKVQVSYV IRDEVEKYNR NGVNALQLDP ALNRLFTAGR DSIIRIWSVN 60
QHKQDPYIAS MEHHTDWVND IVLCCNGKTL ISASSDTTVK VWNAHKGFCM STLRTHKDYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGTGTCAA CATGCAAGAT GGCGGCGCAT CACCGACAGA ATGCGGCCGG GCGCCGGAAA 60
GTGCAGGTGA GAGGTCTGCT GGGCTGCCCG CCGGCGCGGG GTTGTGGCGC GGCTGAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR021772--DUF3337
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF11816--DUF3337
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0000724--P:double-strand break repair via homologous recombination
GO:0048568--P:embryonic organ development
GO:0048872--P:homeostasis of number of cells
GO:0035264--P:multicellular organism growth
GO:0050679--P:positive regulation of epithelial cell proliferation
GO:0016579--P:protein deubiquitination
GO:1902525--P:regulation of protein monoubiquitination
GO:0072520--P:seminiferous tubule development
GO:0007338--P:single fertilization
GO:0048705--P:skeletal system morphogenesis
GO:0043588--P:skin development
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001160	Aegilops tauschii	39.49	6.00e-97	348.00
IUUC-Aml-001533	Ailuropoda melanoleuca	97.65	0.00e+00	1264.00
IUUC-Atr-003009	Amborella trichopoda	33.90	2.00e-111	396.00
IUUC-Apl-003709	Anas platyrhynchos	99.42	0.00e+00	669.00
IUUC-Aca-004875	Anolis carolinensis	98.24	0.00e+00	1301.00
IUUC-Aly-005464	Arabidopsis lyrata	40.00	7.00e-94	338.00
IUUC-Ath-006969	Arabidopsis thaliana	39.41	3.00e-90	325.00
IUUC-Acl-008203	Aspergillus clavatus	35.69	1.00e-47	184.00
IUUC-Afl-008571	Aspergillus flavus	35.63	2.00e-46	180.00
IUUC-Afu-009072	Aspergillus fumigatus	35.03	5.00e-45	176.00
IUUC-Ani-009413	Aspergillus nidulans	36.41	5.00e-48	186.00
IUUC-Ang-009571	Aspergillus niger	35.33	5.00e-45	176.00
IUUC-Aor-010064	Aspergillus oryzae	35.63	1.00e-46	181.00
IUUC-Ate-010463	Aspergillus terreus	35.03	3.00e-46	180.00
IUUC-Ame-010875	Astyanax mexicanus	93.46	0.00e+00	1089.00
IUUC-Bgr-012288	Blumeria graminis	34.01	5.00e-42	166.00
IUUC-Bta-013379	Bos taurus	97.36	0.00e+00	1261.00
IUUC-Bci-013859	Botrytis cinerea	32.39	2.00e-41	164.00
IUUC-Bdi-014645	Brachypodium distachyon	35.11	4.00e-112	399.00
IUUC-Bol-016450	Brassica oleracea	35.61	2.00e-99	356.00
IUUC-Bra-017237	Brassica rapa	34.19	8.00e-102	364.00
IUUC-Cel-018656	Caenorhabditis elegans	44.43	1.00e-155	542.00
IUUC-Cja-018804	Callithrix jacchus	97.36	0.00e+00	1258.00
IUUC-Cfa-020076	Canis familiaris	97.51	0.00e+00	1263.00
IUUC-Cpo-021721	Cavia porcellus	95.95	0.00e+00	1207.00
IUUC-Cre-022779	Chlamydomonas reinhardtii	31.56	4.00e-41	163.00
IUUC-Csa-023188	Chlorocebus sabaeus	97.51	0.00e+00	1263.00
IUUC-Cho-024932	Choloepus hoffmanni	96.33	0.00e+00	1267.00
IUUC-Cin-025591	Ciona intestinalis	56.49	0.00e+00	722.00
IUUC-Cgl-026540	Colletotrichum gloeosporioides	27.55	1.00e-20	95.10
IUUC-Cne-026819	Cryptococcus neoformans	35.53	2.00e-34	141.00
IUUC-Cme-027188	Cyanidioschyzon merolae	31.98	1.00e-71	264.00
IUUC-Dre-027926	Danio rerio	92.38	0.00e+00	1268.00
IUUC-Dno-029960	Dasypus novemcinctus	96.92	0.00e+00	1252.00
IUUC-Dor-030933	Dipodomys ordii	93.77	0.00e+00	707.00
IUUC-Dse-031532	Dothistroma septosporum	35.07	1.00e-45	178.00
IUUC-Dme-032168	Drosophila melanogaster	56.41	0.00e+00	684.00
IUUC-Ete-033107	Echinops telfairi	93.40	0.00e+00	1192.00
IUUC-Eca-034028	Equus caballus	97.65	0.00e+00	1265.00
IUUC-Eeu-034894	Erinaceus europaeus	95.71	0.00e+00	845.00
IUUC-Fca-035619	Felis catus	96.81	0.00e+00	948.00
IUUC-Fal-036869	Ficedula albicollis	98.65	0.00e+00	1271.00
IUUC-Fox-037907	Fusarium oxysporum	32.49	2.00e-41	164.00
IUUC-Fso-038101	Fusarium solani	32.96	4.00e-41	163.00
IUUC-Gmo-038627	Gadus morhua	94.87	0.00e+00	1290.00
IUUC-Ggr-039995	Gaeumannomyces graminis	31.28	2.00e-42	167.00
IUUC-Gga-040555	Gallus gallus	98.53	0.00e+00	1304.00
IUUC-Gac-042497	Gasterosteus aculeatus	94.72	0.00e+00	1259.00
IUUC-Gma-043089	Glycine max	34.61	4.00e-110	392.00
IUUC-Ggo-045561	Gorilla gorilla	97.51	0.00e+00	1263.00
IUUC-Hsa-045710	Homo sapiens	97.51	0.00e+00	1263.00
IUUC-Hvu-047730	Hordeum vulgare	35.98	1.00e-84	306.00
IUUC-Itr-049030	Ictidomys tridecemlineatus	97.08	0.00e+00	891.00
IUUC-Kpa-049237	Komagataella pastoris	30.98	2.00e-30	127.00
IUUC-Lch-049507	Latimeria chalumnae	97.07	0.00e+00	1269.00
IUUC-Lpe-051608	Leersia perrieri	35.01	2.00e-109	389.00
IUUC-Loc-052373	Lepisosteus oculatus	93.57	0.00e+00	1248.00
IUUC-Lma-053025	Leptosphaeria maculans	36.45	2.00e-48	187.00
IUUC-Laf-053706	Loxodonta africana	97.00	0.00e+00	1227.00
IUUC-Mcc-055046	Macaca mulatta	97.51	0.00e+00	1263.00
IUUC-Meu-056840	Macropus eugenii	79.82	4.00e-149	521.00
IUUC-Mor-057284	Magnaporthe oryzae	32.93	4.00e-43	170.00
IUUC-Mpo-057418	Magnaporthe poae	30.73	7.00e-41	162.00
IUUC-Mtr-058571	Medicago truncatula	34.74	5.00e-109	388.00
IUUC-Mla-059101	Melampsora laricipopulina	44.61	2.00e-45	178.00
IUUC-Mga-059297	Meleagris gallopavo	98.53	0.00e+00	1304.00
IUUC-Mvi-060419	Microbotryum violaceum	39.57	3.00e-38	154.00
IUUC-Mmr-061196	Microcebus murinus	91.16	0.00e+00	1140.00
IUUC-Mdo-062762	Monodelphis domestica	94.46	0.00e+00	1284.00
IUUC-Mmu-063915	Mus musculus	96.63	0.00e+00	1280.00
IUUC-Mac-065434	Musa acuminata	34.42	2.00e-107	383.00
IUUC-Mpu-065999	Mustela putorius furo	98.13	0.00e+00	841.00
IUUC-Mlu-068226	Myotis lucifugus	97.06	0.00e+00	1254.00
IUUC-Nfi-068416	Neosartorya fischeri	29.75	2.00e-55	211.00
IUUC-Ncr-068825	Neurospora crassa	31.34	1.00e-39	158.00
IUUC-Nle-069416	Nomascus leucogenys	97.51	0.00e+00	1263.00
IUUC-Opr-070515	Ochotona princeps	92.82	0.00e+00	1183.00
IUUC-Ont-072052	Oreochromis niloticus	93.70	0.00e+00	1205.00
IUUC-Oan-073636	Ornithorhynchus anatinus	94.45	0.00e+00	1250.00
IUUC-Ocu-074799	Oryctolagus cuniculus	97.36	0.00e+00	1260.00
IUUC-Oba-075146	Oryza barthii	35.31	4.00e-110	392.00
IUUC-Obr-076699	Oryza brachyantha	35.03	9.00e-111	394.00
IUUC-Ogl-077883	Oryza glaberrima	34.07	1.00e-66	246.00
IUUC-Ogu-078114	Oryza glumaepatula	34.91	6.00e-109	388.00
IUUC-Oin-079575	Oryza indica	35.33	3.00e-113	402.00
IUUC-Olo-080531	Oryza longistaminata	32.91	2.00e-99	356.00
IUUC-Ome-081368	Oryza meridionalis	40.12	6.00e-98	351.00
IUUC-Oni-082457	Oryza nivara	35.31	4.00e-110	392.00
IUUC-Opu-084050	Oryza punctata	35.18	4.00e-109	388.00
IUUC-Oru-084330	Oryza rufipogon	35.31	4.00e-110	392.00
IUUC-Osa-085408	Oryza sativa	35.33	3.00e-113	402.00
IUUC-Ola-087546	Oryzias latipes	95.18	0.00e+00	1274.00
IUUC-Olu-087710	Ostreococcus lucimarinus	30.57	2.00e-79	289.00
IUUC-Oga-087998	Otolemur garnettii	96.02	0.00e+00	1233.00
IUUC-Oar-090303	Ovis aries	97.36	0.00e+00	1261.00
IUUC-Ptr-090588	Pan troglodytes	97.51	0.00e+00	1263.00
IUUC-Pan-092722	Papio anubis	97.51	0.00e+00	1263.00
IUUC-Pma-094580	Petromyzon marinus	87.81	0.00e+00	1189.00
IUUC-Pno-095085	Phaeosphaeria nodorum	34.71	3.00e-43	170.00
IUUC-Ppa-095594	Physcomitrella patens	35.72	3.00e-113	402.00
IUUC-Pfo-096994	Poecilia formosa	94.46	0.00e+00	1261.00
IUUC-Pab-097586	Pongo abelii	97.36	0.00e+00	1260.00
IUUC-Pop-099740	Populus trichocarpa	34.42	3.00e-104	372.00
IUUC-Pca-100458	Procavia capensis	97.60	2.00e-106	379.00
IUUC-Ppe-102060	Prunus persica	34.11	7.00e-109	387.00
IUUC-Pva-102698	Pteropus vampyrus	93.26	0.00e+00	1245.00
IUUC-Pgr-103649	Puccinia graminis	39.08	6.00e-48	186.00
IUUC-Ptt-103910	Puccinia triticina	39.04	2.00e-52	201.00
IUUC-Pte-104181	Pyrenophora teres	36.14	2.00e-48	187.00
IUUC-Pyt-104439	Pyrenophora triticirepentis	35.84	6.00e-48	186.00
IUUC-Rno-104978	Rattus norvegicus	96.85	0.00e+00	1250.00
IUUC-Sha-107079	Sarcophilus harrisii	96.13	0.00e+00	1204.00
IUUC-Sja-107716	Schizosaccharomyces japonicus	30.36	2.00e-58	220.00
IUUC-Spo-108325	Schizosaccharomyces pombe	29.66	6.00e-52	199.00
IUUC-Ssl-108542	Sclerotinia sclerotiorum	28.68	7.00e-45	176.00
IUUC-Smo-109427	Selaginella moellendorffii	35.04	4.00e-109	388.00
IUUC-Sit-110755	Setaria italica	36.11	2.00e-114	406.00
IUUC-Sly-111099	Solanum lycopersicum	35.21	3.00e-98	352.00
IUUC-Sar-113408	Sorex araneus	98.47	0.00e+00	767.00
IUUC-Sbi-113789	Sorghum bicolor	34.73	5.00e-111	395.00
IUUC-Sre-114998	Sporisorium reilianum	40.92	5.00e-53	203.00
IUUC-Ssc-115434	Sus scrofa	97.51	0.00e+00	1263.00
IUUC-Tgu-116517	Taeniopygia guttata	98.68	0.00e+00	1302.00
IUUC-Tru-118174	Takifugu rubripes	95.31	0.00e+00	1272.00
IUUC-Tsy-118935	Tarsius syrichta	97.51	0.00e+00	1287.00
IUUC-Tni-119744	Tetraodon nigroviridis	94.87	0.00e+00	1233.00
IUUC-Tca-121360	Theobroma cacao	34.24	4.00e-112	398.00
IUUC-Tre-122198	Trichoderma reesei	32.29	4.00e-43	169.00
IUUC-Tvi-122389	Trichoderma virens	32.57	4.00e-43	169.00
IUUC-Tae-125576	Triticum aestivum	35.34	3.00e-113	402.00
IUUC-Tur-126699	Triticum urartu	34.75	1.00e-110	393.00
IUUC-Tme-126932	Tuber melanosporum	31.29	1.00e-54	208.00
IUUC-Tbe-127267	Tupaia belangeri	82.75	0.00e+00	728.00
IUUC-Ttr-129153	Tursiops truncatus	97.21	0.00e+00	1291.00
IUUC-Uma-129604	Ustilago maydis	38.20	2.00e-50	194.00
IUUC-Vda-129925	Verticillium dahliae	34.68	3.00e-46	180.00
IUUC-Vpa-130553	Vicugna pacos	96.23	0.00e+00	969.00
IUUC-Vvi-130995	Vitis vinifera	34.11	3.00e-108	385.00
IUUC-Xtr-132346	Xenopus tropicalis	95.01	0.00e+00	1239.00
IUUC-Xma-134266	Xiphophorus maculatus	91.95	0.00e+00	666.00
IUUC-Yli-134451	Yarrowia lipolytica	31.19	1.00e-35	144.00
IUUC-Zma-135647	Zea mays	35.46	4.00e-113	402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence