iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aly-006422

UUCD1 version

UUC-ArL-01264

Ensembl Protein ID

Al_scaffold_0004_1740

UniProt Accession

D7LFL0; D7LFL0_ARALL

Genbank Protein ID

EFH57499.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

GL348716

Gene Name

UBP1; ARALYDRAFT_669021

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Al_scaffold_0004_1740	Al_scaffold_0004_1740	Al_scaffold_0004_1740

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-79	268.0	225	1097

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeef 84
           Gl NlgNtC++NSv+Q+L+++ +lre +l+    +       + +g+l++sl+klf+e        ++a++pr+l+ ++++ a++f
   Q: 225  GLVNLGNTCFFNSVMQSLLSLDQLREHFLK---DD------LSVSGPLVSSLKKLFAESKseaGFFRSAINPRALFVSVCSQAPQF 301
           9*****************************...33......345689***********9655555677****************** PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
           +gy+q+D++E+l++lld+l+ e ++     ++++   d       ++++ + ++++li+ +F+g+++s++ cl+c++ s+ +epfl
   Q: 302  RGYQQHDSHELLRCLLDGLSIEESS----LRKKLGVFD-------SNDSSTYQKPTLIDSVFGGEISSTVSCLACGHFSKVYEPFL 376
           ********************99922....222222222.......4478889999******************************* PP
   S: 171  dlslpvpgkeetkke....................................................................... 185
           dlslp+p+k+   k+                                                                       
   Q: 377  DLSLPIPSKKLPPKKqrivslakevlkngavgkdsevgsakpasdhnftvsnpsamalidkqvsdittesdteqyeldkfwsdldl 462
           **********876669********************************************************************** PP
   S: 186  ...................................................................................... 185
                                                                                                 
   Q: 463  lgdvsdtapstkakgvnqtlvgstetlmhdndvtakpetvpdkeesratqsnedtsasgisavideaqvfrspdfekssssanqwa 548
           ************************************************************************************** PP
   S: 186  ...................................................................................... 185
                                                                                                 
   Q: 549  deelplmvpdsqvlympykdhlsyddntvaegkdgaflsyvsgpheqiedhfdcnadepgissinitdragegeasssfvsgdhep 634
           ************************************************************************************** PP
   S: 186  ...................................................................................... 185
                                                                                                 
   Q: 635  kidyidfssffdepeipegpvfrllskaevseagfmadssndktvsagkgeasssfvssdheqnidyvdfasffdepeisegpyfr 720
           ************************************************************************************** PP
   S: 186  ...................................................................................... 185
                                                                                                 
   Q: 721  plsksevseagfmavssndktvragkgetfssfmngdnernidyesinslfydretserpvfgppskakvseacfmavssdsdpav 806
           ************************************************************************************** PP
   S: 186  ........slqdcLesftkeeelegenkyycekck................................................... 212
                   s++ cL++ftk+e l ++n+++ce+c                                                    
   Q: 807  lddsdspvSVDRCLAQFTKPEILSEDNAWHCENCSknlklerlrekrkterlskgwvnengassvfdecrdnslsqscidpengyk 892
           ************************************************************************************** PP
   S: 213  ........................................................................kkqeaekklklkkl 226
                                                                                    k+ a+kk+ ++k 
   Q: 893  aappitelpnckeeenaiddgilgdsdpkqapitssvtetpilggetissqpandnecenwedlavdsekviVKRAATKKVLVNKA 978
           *********************************9999999999999999999999999999999999888887778********** PP
   S: 227  PevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn........... 301
           P+vL++hLkRfs + + ++ +k++ +v+f + +dls+++ +++++++ +  Y+L + v H G++++GHYvay++            
   Q: 979  PPVLTIHLKRFSQDAR-GRISKLSGHVDFQEFIDLSQYMDTRCSEED-QPVYRLAGLVEHLGTMRGGHYVAYIRGghkemrqsdik 1062
           ***********77665.8889*********99*********998875.99*************************77666666554 PP
   S: 302  ekgk....WllfdDskVtevkeeevleetgstaYvlfYkr 337
           e       W++ +Ds V+  + eevl+   s+aY+lfY+r
   Q: 1063 E--PnssiWYHASDSFVRRASLEEVLR---SEAYILFYER 1097
           1..05567*******************...********98 PP

Organism

Arabidopsis lyrata

Protein Sequence
(Fasta)

MGKRLKKGQK PPYLWLPPTV SKKVTKQSEH SVEVTEEVVT VPEKRSCVHF DKFVDLDKLL 60
KKIKSSQQIK CGECKEGVHV KRGSKASISS GIYWFSSSDQ KCAKKAIWVC LECGYYVCGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAAAGA GATTAAAGAA GGGTCAAAAG CCTCCATATC TGTGGTTGCC TCCAACGGTC 60
TCTAAGAAGG TAACTAAGCA ATCTGAGCAC AGCGTGGAGG TAACTGAGGA GGTTGTGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aly:ARALYDRAFT_669021

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001931	Ailuropoda melanoleuca	28.57	2.00e-34	140.00
IUUC-Apl-003512	Anas platyrhynchos	29.77	4.00e-36	145.00
IUUC-Aca-004284	Anolis carolinensis	28.68	1.00e-33	137.00
IUUC-Ath-006732	Arabidopsis thaliana	72.97	0.00e+00	1059.00
IUUC-Ame-011659	Astyanax mexicanus	36.62	6.00e-28	119.00
IUUC-Bta-013362	Bos taurus	29.19	3.00e-36	146.00
IUUC-Bdi-014624	Brachypodium distachyon	35.82	2.00e-48	187.00
IUUC-Bra-016751	Brassica rapa	52.31	1.00e-141	497.00
IUUC-Cja-019177	Callithrix jacchus	28.86	2.00e-35	143.00
IUUC-Cfa-020051	Canis familiaris	28.50	3.00e-34	139.00
IUUC-Cpo-021886	Cavia porcellus	28.93	3.00e-36	146.00
IUUC-Csa-024103	Chlorocebus sabaeus	28.86	2.00e-35	144.00
IUUC-Cin-025775	Ciona intestinalis	34.75	7.00e-19	85.50
IUUC-Dre-028388	Danio rerio	29.94	4.00e-32	132.00
IUUC-Dno-029409	Dasypus novemcinctus	28.75	3.00e-36	146.00
IUUC-Dme-031870	Drosophila melanogaster	29.83	1.00e-18	88.60
IUUC-Eca-033479	Equus caballus	29.44	2.00e-35	143.00
IUUC-Fca-036320	Felis catus	29.00	9.00e-36	144.00
IUUC-Fal-037199	Ficedula albicollis	29.87	1.00e-36	147.00
IUUC-Gmo-039480	Gadus morhua	30.95	2.00e-32	133.00
IUUC-Gga-040527	Gallus gallus	30.12	3.00e-33	136.00
IUUC-Gac-042406	Gasterosteus aculeatus	32.12	5.00e-32	132.00
IUUC-Ggo-045598	Gorilla gorilla	28.35	2.00e-34	140.00
IUUC-Hsa-046598	Homo sapiens	28.35	1.00e-34	140.00
IUUC-Hvu-047146	Hordeum vulgare	34.49	1.00e-49	191.00
IUUC-Itr-047951	Ictidomys tridecemlineatus	28.17	9.00e-36	144.00
IUUC-Lch-050536	Latimeria chalumnae	29.75	3.00e-33	136.00
IUUC-Lpe-050703	Leersia perrieri	40.79	1.00e-49	191.00
IUUC-Loc-051814	Lepisosteus oculatus	28.50	3.00e-32	132.00
IUUC-Laf-053988	Loxodonta africana	31.03	1.00e-36	147.00
IUUC-Mcc-054661	Macaca mulatta	28.61	6.00e-35	142.00
IUUC-Mga-059551	Meleagris gallopavo	28.38	2.00e-33	137.00
IUUC-Mmr-061747	Microcebus murinus	28.61	1.00e-33	137.00
IUUC-Mdo-062220	Monodelphis domestica	30.18	1.00e-34	141.00
IUUC-Mmu-063582	Mus musculus	27.75	1.00e-34	140.00
IUUC-Mpu-066339	Mustela putorius furo	28.00	3.00e-34	139.00
IUUC-Mlu-067511	Myotis lucifugus	29.44	3.00e-34	139.00
IUUC-Nle-069252	Nomascus leucogenys	28.61	4.00e-35	142.00
IUUC-Opr-070969	Ochotona princeps	27.41	2.00e-32	133.00
IUUC-Ont-071786	Oreochromis niloticus	27.99	4.00e-35	142.00
IUUC-Oan-073656	Ornithorhynchus anatinus	29.09	9.00e-36	144.00
IUUC-Ocu-074704	Oryctolagus cuniculus	27.41	1.00e-32	134.00
IUUC-Oba-075094	Oryza barthii	41.79	5.00e-52	199.00
IUUC-Obr-076743	Oryza brachyantha	40.07	2.00e-48	187.00
IUUC-Ogl-077739	Oryza glaberrima	41.79	2.00e-52	200.00
IUUC-Ogu-078851	Oryza glumaepatula	41.07	3.00e-52	199.00
IUUC-Oin-079402	Oryza indica	41.07	3.00e-52	199.00
IUUC-Olo-080431	Oryza longistaminata	41.07	2.00e-52	200.00
IUUC-Ome-081580	Oryza meridionalis	41.07	3.00e-52	199.00
IUUC-Oni-082644	Oryza nivara	41.07	3.00e-52	199.00
IUUC-Opu-083452	Oryza punctata	40.79	2.00e-51	197.00
IUUC-Oru-084546	Oryza rufipogon	41.07	3.00e-52	199.00
IUUC-Osa-085858	Oryza sativa	41.07	3.00e-52	199.00
IUUC-Ola-086795	Oryzias latipes	28.68	6.00e-33	135.00
IUUC-Oga-088713	Otolemur garnettii	28.82	5.00e-35	142.00
IUUC-Oar-089887	Ovis aries	28.61	2.00e-35	144.00
IUUC-Ptr-091670	Pan troglodytes	28.10	4.00e-34	139.00
IUUC-Pan-092293	Papio anubis	28.61	6.00e-35	142.00
IUUC-Psi-093101	Pelodiscus sinensis	31.07	4.00e-34	139.00
IUUC-Pfo-097202	Poecilia formosa	29.02	6.00e-33	135.00
IUUC-Pab-098539	Pongo abelii	27.44	5.00e-34	139.00
IUUC-Rno-105237	Rattus norvegicus	27.43	7.00e-34	138.00
IUUC-Sha-107022	Sarcophilus harrisii	30.03	3.00e-35	142.00
IUUC-Sja-107712	Schizosaccharomyces japonicus	32.90	1.00e-18	87.80
IUUC-Sar-113530	Sorex araneus	29.00	8.00e-35	141.00
IUUC-Ssc-116091	Sus scrofa	28.32	2.00e-34	140.00
IUUC-Tgu-116907	Taeniopygia guttata	29.77	1.00e-36	147.00
IUUC-Tru-118640	Takifugu rubripes	29.57	7.00e-37	148.00
IUUC-Tsy-118869	Tarsius syrichta	29.43	1.00e-27	117.00
IUUC-Tni-120015	Tetraodon nigroviridis	28.93	4.00e-33	136.00
IUUC-Tae-125305	Triticum aestivum	38.41	9.00e-46	178.00
IUUC-Tur-126788	Triticum urartu	37.68	3.00e-45	176.00
IUUC-Tbe-128041	Tupaia belangeri	32.56	2.00e-25	110.00
IUUC-Ttr-128271	Tursiops truncatus	29.25	3.00e-36	146.00
IUUC-Vpa-130674	Vicugna pacos	28.35	3.00e-34	139.00
IUUC-Xtr-131869	Xenopus tropicalis	29.26	4.00e-34	139.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence