iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000011794.2	ENSSSCT00000024072.1	ENSSSCP00000021823.1
ENSSSCG00000011794.2	ENSSSCT00000012906.2	ENSSSCP00000012565.2
ENSSSCG00000011794.2	ENSSSCT00000029102.1	ENSSSCP00000025432.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/ULP	4.80e-54	183.4	399	561

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/ULP

   S: 2    svtnedlkcLeegeflnDviidfylkylvleklkkekverihifssffykklkqkerrrvktwtrkvdlfekdlifvpineaaHWslav 90
            +t+ d+++L++ ++lnD++i+fy++ l++e+ kk+ ++ + +fs+ffy klk+ ++++vk+wt+ v+lfe++li+vpi++++HWsl+v
   Q: 399  RITRGDIQTLKNYHWLNDEVINFYMN-LLMERNKKQGYPALYAFSTFFYPKLKSGGYQAVKRWTKGVNLFEQELILVPIHRKVHWSLVV 486
           699***********************.************************************************************** PP
   S: 91   vcfkkksilllDSlrgasksnvvkklreylevevkkkskrefskeklkgsnpk...vpqQkNssDCGvyvlqyves 163
           ++++kk++ +lDS+ g++ ++++++l +yl++e+k+k++++++  ++ +++ k   +pqQ N+sDCG++ ++y+++
   Q: 487  IDLRKKCLKYLDSM-GQKGHRICEILLQYLQDESKTKRNIDLNLLEWTHYSLKpheIPQQLNGSDCGMFTCKYADY 561
           **************.*********************************99988889*****************986 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MYKWLVRILG TIFRFCDRPV PSSRALLKRR RSNSSLFSTV DTDEVPAKRP RLDCFIHQVK 60
TSLYNAASLF GFPFQLTTKP MVTSACNGTR NVAPSGEFFS YLSMCEESGI VTFYNYKCIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAGTG GTCCTTACCT CTACTGTGGA CGACAGGACA TCGAAGGCAC CAACTGGCAG 60
ACAAGACCCA AGCGGAAGCG ACTGTAAGGC TGAATCCCCT TTCTTTCTCC ACTTCAGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003653--Peptidase_C48_C

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0005643--C:nuclear pore
GO:0005634--C:nucleus
GO:0016605--C:PML body
GO:0004175--F:endopeptidase activity
GO:0016929--F:SUMO-specific protease activity
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0060711--P:labyrinthine layer development
GO:0035562--P:negative regulation of chromatin binding
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0031397--P:negative regulation of protein ubiquitination
GO:0031398--P:positive regulation of protein ubiquitination
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0031648--P:protein destabilization
GO:0016926--P:protein desumoylation
GO:0032875--P:regulation of DNA endoreduplication
GO:2000045--P:regulation of G1/S transition of mitotic cell cycle
GO:0060712--P:spongiotrophoblast layer development
GO:0060707--P:trophoblast giant cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001512	Ailuropoda melanoleuca	91.74	0.00e+00	1054.00
IUUC-Apl-003602	Anas platyrhynchos	50.82	4.00e-114	404.00
IUUC-Aca-004819	Anolis carolinensis	45.47	1.00e-106	379.00
IUUC-Aly-006429	Arabidopsis lyrata	34.87	2.00e-33	136.00
IUUC-Ath-007377	Arabidopsis thaliana	39.30	7.00e-37	148.00
IUUC-Afl-008417	Aspergillus flavus	30.30	9.00e-30	125.00
IUUC-Aor-010104	Aspergillus oryzae	32.04	1.00e-28	119.00
IUUC-Ame-011519	Astyanax mexicanus	39.70	9.00e-75	274.00
IUUC-Bta-013157	Bos taurus	90.88	0.00e+00	1070.00
IUUC-Cja-018720	Callithrix jacchus	89.38	0.00e+00	1036.00
IUUC-Cfa-020805	Canis familiaris	92.24	0.00e+00	1056.00
IUUC-Cpo-021808	Cavia porcellus	87.33	0.00e+00	1009.00
IUUC-Cre-022877	Chlamydomonas reinhardtii	32.04	3.00e-19	87.40
IUUC-Cho-024783	Choloepus hoffmanni	65.05	7.00e-175	606.00
IUUC-Dno-028882	Dasypus novemcinctus	90.03	0.00e+00	1043.00
IUUC-Dor-030693	Dipodomys ordii	66.55	0.00e+00	697.00
IUUC-Ete-032724	Echinops telfairi	75.21	0.00e+00	836.00
IUUC-Eca-034052	Equus caballus	91.72	0.00e+00	1062.00
IUUC-Eeu-034465	Erinaceus europaeus	87.59	0.00e+00	920.00
IUUC-Fca-036319	Felis catus	92.24	0.00e+00	1065.00
IUUC-Fal-037347	Ficedula albicollis	55.56	2.00e-85	308.00
IUUC-Gga-041045	Gallus gallus	63.33	5.00e-100	358.00
IUUC-Ggo-044694	Gorilla gorilla	82.94	0.00e+00	935.00
IUUC-Hsa-045920	Homo sapiens	89.86	0.00e+00	1041.00
IUUC-Itr-048799	Ictidomys tridecemlineatus	89.70	0.00e+00	1040.00
IUUC-Lch-049790	Latimeria chalumnae	64.53	8.00e-89	319.00
IUUC-Lma-052978	Leptosphaeria maculans	34.39	4.00e-20	92.80
IUUC-Laf-053368	Loxodonta africana	87.67	0.00e+00	1015.00
IUUC-Mcc-055057	Macaca mulatta	90.03	0.00e+00	1039.00
IUUC-Meu-056435	Macropus eugenii	56.13	0.00e+00	629.00
IUUC-Mtr-058391	Medicago truncatula	37.34	1.00e-35	144.00
IUUC-Mmr-061684	Microcebus murinus	90.71	0.00e+00	1060.00
IUUC-Mdo-062858	Monodelphis domestica	69.79	2.00e-134	471.00
IUUC-Mmu-063498	Mus musculus	85.16	0.00e+00	972.00
IUUC-Mpu-066611	Mustela putorius furo	89.15	0.00e+00	1005.00
IUUC-Mlu-067118	Myotis lucifugus	85.45	0.00e+00	1040.00
IUUC-Ncr-068706	Neurospora crassa	29.24	4.00e-17	83.60
IUUC-Nle-069443	Nomascus leucogenys	90.03	0.00e+00	1046.00
IUUC-Opr-070806	Ochotona princeps	77.06	0.00e+00	870.00
IUUC-Oan-073590	Ornithorhynchus anatinus	56.68	3.00e-79	287.00
IUUC-Ocu-073901	Oryctolagus cuniculus	88.70	0.00e+00	1047.00
IUUC-Oga-089135	Otolemur garnettii	90.03	0.00e+00	1046.00
IUUC-Oar-089942	Ovis aries	91.55	0.00e+00	1085.00
IUUC-Ptr-090705	Pan troglodytes	90.03	0.00e+00	1047.00
IUUC-Pan-092887	Papio anubis	89.29	0.00e+00	845.00
IUUC-Psi-093140	Pelodiscus sinensis	51.88	5.00e-140	491.00
IUUC-Pno-094805	Phaeosphaeria nodorum	35.44	2.00e-21	97.40
IUUC-Pab-098511	Pongo abelii	93.86	1.00e-156	546.00
IUUC-Pca-100253	Procavia capensis	62.39	0.00e+00	631.00
IUUC-Ppe-101189	Prunus persica	36.53	5.00e-33	135.00
IUUC-Pva-103179	Pteropus vampyrus	88.68	0.00e+00	1014.00
IUUC-Pte-104020	Pyrenophora teres	32.72	1.00e-17	84.70
IUUC-Pyt-104575	Pyrenophora triticirepentis	31.65	2.00e-18	87.40
IUUC-Rno-105258	Rattus norvegicus	84.82	0.00e+00	954.00
IUUC-Sha-107397	Sarcophilus harrisii	39.37	2.00e-96	346.00
IUUC-Stu-112651	Solanum tuberosum	37.39	2.00e-35	143.00
IUUC-Sar-113372	Sorex araneus	87.32	0.00e+00	882.00
IUUC-Tgu-117433	Taeniopygia guttata	59.91	2.00e-84	304.00
IUUC-Tsy-118960	Tarsius syrichta	78.85	0.00e+00	785.00
IUUC-Tbe-127893	Tupaia belangeri	62.76	4.00e-180	624.00
IUUC-Ttr-128910	Tursiops truncatus	92.11	0.00e+00	989.00
IUUC-Vda-129779	Verticillium dahliae	24.08	1.00e-11	65.10
IUUC-Vpa-130290	Vicugna pacos	92.57	0.00e+00	1100.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence