iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074825

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02052081

Gene Name

TRIM38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000004429.3	ENSOCUT00000004428.3	ENSOCUP00000003828.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.10e-09	37.4	12	83
E3 activity/RING/RING	4.40e-06	27.2	16	63

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk........tcPvtrqplteedlvPnltlrrliqa 67
           ee  C+I l+lM+dP+ +++G++y  ++I  +l++ ++         cP +r+p ++e+l Pn+ l +li+a
   Q: 12   EEATCSICLNLMSDPTSVACGHSYCGQCIVDFLNNLRQsqvlqntfPCPQCRAPCSQESLRPNKQLGNLIEA 83
           6789*****************************88888899999999**********************997 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl....qkwpglknssskefrCPlCr 46
           C+iCl+ ++d p ++ CgH ++ +C+    +++  ++++ +++f CP Cr
   Q: 16   CSICLNLMSD-PTSVACGHSYCGQCIvdflNNL-RQSQVLQNTFPCPQCR 63
           **********.999***********87666777.9999***********8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MTSAPSTKRM REEATCSICL NLMSDPTSVA CGHSYCGQCI VDFLNNLRQS QVLQNTFPCP 60
QCRAPCSQES LRPNKQLGNL IEAIKEMEQG MSCKEHGEQL QLFCEDEGQL ICWRCERTSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGAGGGT GCCCAGGGCG GAAGGGTCTC CACCCTTGGC TCAGCTTCCT GCTCACAGCA 60
CGCCGCGCGG GGCTCACAGG GCAGCTCCGG GCTCACTGAT TTGTCCCTTC CTGTCGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004871--F:signal transducer activity
GO:0008270--F:zinc ion binding
GO:0050687--P:negative regulation of defense response to virus
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0032648--P:regulation of interferon-beta production

KEGG

ocu:100350255

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001649	Ailuropoda melanoleuca	69.05	0.00e+00	674.00
IUUC-Bta-012574	Bos taurus	69.78	0.00e+00	671.00
IUUC-Cja-019759	Callithrix jacchus	70.78	0.00e+00	631.00
IUUC-Cfa-020431	Canis familiaris	68.60	0.00e+00	656.00
IUUC-Cpo-022541	Cavia porcellus	62.05	4.00e-175	607.00
IUUC-Csa-023320	Chlorocebus sabaeus	69.68	0.00e+00	678.00
IUUC-Cho-024964	Choloepus hoffmanni	66.77	1.00e-118	419.00
IUUC-Dno-029741	Dasypus novemcinctus	63.01	4.00e-170	590.00
IUUC-Dor-030298	Dipodomys ordii	59.66	7.00e-100	356.00
IUUC-Ete-032493	Echinops telfairi	60.95	4.00e-167	580.00
IUUC-Eca-033962	Equus caballus	70.97	0.00e+00	671.00
IUUC-Eeu-035228	Erinaceus europaeus	63.11	4.00e-119	421.00
IUUC-Fca-036349	Felis catus	69.11	0.00e+00	667.00
IUUC-Ggo-044493	Gorilla gorilla	70.75	0.00e+00	691.00
IUUC-Hsa-046161	Homo sapiens	70.32	0.00e+00	688.00
IUUC-Itr-048162	Ictidomys tridecemlineatus	57.58	3.00e-143	501.00
IUUC-Laf-054150	Loxodonta africana	67.74	0.00e+00	633.00
IUUC-Mcc-055076	Macaca mulatta	69.68	0.00e+00	680.00
IUUC-Mmu-063517	Mus musculus	52.03	6.00e-137	480.00
IUUC-Mpu-065752	Mustela putorius furo	70.35	0.00e+00	684.00
IUUC-Mlu-067758	Myotis lucifugus	56.25	2.00e-144	506.00
IUUC-Nle-069117	Nomascus leucogenys	70.84	0.00e+00	687.00
IUUC-Opr-071144	Ochotona princeps	82.80	0.00e+00	777.00
IUUC-Oga-088744	Otolemur garnettii	68.14	1.00e-117	415.00
IUUC-Oar-089951	Ovis aries	70.65	0.00e+00	678.00
IUUC-Ptr-090519	Pan troglodytes	70.54	0.00e+00	690.00
IUUC-Pan-092059	Papio anubis	69.68	0.00e+00	681.00
IUUC-Pab-098747	Pongo abelii	70.54	0.00e+00	687.00
IUUC-Pca-100294	Procavia capensis	64.95	9.00e-180	622.00
IUUC-Pva-102129	Pteropus vampyrus	63.36	3.00e-177	614.00
IUUC-Sar-113760	Sorex araneus	59.52	2.00e-148	519.00
IUUC-Tsy-119422	Tarsius syrichta	68.39	0.00e+00	637.00
IUUC-Tbe-127628	Tupaia belangeri	58.76	6.00e-95	340.00
IUUC-Ttr-129039	Tursiops truncatus	71.40	0.00e+00	687.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence