iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015841

Ensembl Protein ID

Bo5g009190.1

UniProt Accession

A0A0D3C8K1; A0A0D3C8K1_BRAOL

Protein Name

Presenilin

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo5g009190	Bo5g009190.1	Bo5g009190.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	30.75	2.00e-36	149.00	IUUC-Cel-018553

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Brassica oleracea

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MESSSILDSL GVEIIGVMAP VSICMFLVVL LTYSLSVTSD PQIRTAANLI YIENPSDSAT 60
VKLEGSLENA IVFVVLVAFV TFVLVLLFYY NFTNFLKHYM RFSAFFVLGT MGGAIFLSII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTCAA GTAGCATCCT CGATTCCCTC GGAGTCGAGA TAATCGGCGT GATGGCTCCC 60
GTCTCCATCT GCATGTTCCT CGTCGTCCTC CTCACCTACT CCCTCTCCGT CACCTCCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	50.43	7.00e-82	298.00
IUUC-Aml-001648	Ailuropoda melanoleuca	36.71	1.00e-33	137.00
IUUC-Atr-003039	Amborella trichopoda	59.83	8.00e-131	459.00
IUUC-Apl-003727	Anas platyrhynchos	31.41	1.00e-32	133.00
IUUC-Aca-004582	Anolis carolinensis	34.70	4.00e-36	145.00
IUUC-Aly-005455	Arabidopsis lyrata	82.04	1.00e-174	605.00
IUUC-Ath-006730	Arabidopsis thaliana	80.53	7.00e-176	609.00
IUUC-Ame-010686	Astyanax mexicanus	31.13	2.00e-33	136.00
IUUC-Bta-013026	Bos taurus	31.91	2.00e-35	142.00
IUUC-Bdi-014196	Brachypodium distachyon	53.29	2.00e-94	339.00
IUUC-Bra-017580	Brassica rapa	93.29	2.00e-169	588.00
IUUC-Cel-018553	Caenorhabditis elegans	31.22	2.00e-45	176.00
IUUC-Cja-019994	Callithrix jacchus	33.41	9.00e-35	140.00
IUUC-Cfa-020074	Canis familiaris	33.33	3.00e-36	145.00
IUUC-Cpo-022237	Cavia porcellus	33.88	8.00e-36	144.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	45.61	9.00e-50	191.00
IUUC-Csa-023537	Chlorocebus sabaeus	34.22	9.00e-36	144.00
IUUC-Cho-024735	Choloepus hoffmanni	31.73	3.00e-31	129.00
IUUC-Cin-025780	Ciona intestinalis	31.43	6.00e-42	164.00
IUUC-Csv-025967	Ciona savignyi	32.09	8.00e-25	107.00
IUUC-Dre-028526	Danio rerio	34.06	2.00e-39	156.00
IUUC-Dno-029758	Dasypus novemcinctus	32.86	1.00e-34	140.00
IUUC-Dor-030609	Dipodomys ordii	39.86	1.00e-20	94.00
IUUC-Dme-031929	Drosophila melanogaster	30.65	2.00e-42	166.00
IUUC-Ete-032487	Echinops telfairi	36.05	1.00e-16	80.90
IUUC-Eca-033391	Equus caballus	30.42	1.00e-20	93.60
IUUC-Eeu-035134	Erinaceus europaeus	34.20	4.00e-32	131.00
IUUC-Fca-036243	Felis catus	33.10	9.00e-37	147.00
IUUC-Fal-036600	Ficedula albicollis	31.33	1.00e-33	137.00
IUUC-Gmo-038550	Gadus morhua	32.09	8.00e-24	104.00
IUUC-Gga-040993	Gallus gallus	31.89	9.00e-34	137.00
IUUC-Gac-042511	Gasterosteus aculeatus	32.70	8.00e-35	140.00
IUUC-Gma-043822	Glycine max	70.80	9.00e-53	200.00
IUUC-Ggo-045338	Gorilla gorilla	29.52	7.00e-23	101.00
IUUC-Hsa-046822	Homo sapiens	34.22	9.00e-36	144.00
IUUC-Hvu-047141	Hordeum vulgare	51.75	1.00e-88	319.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	34.97	3.00e-33	135.00
IUUC-Lch-049946	Latimeria chalumnae	31.16	1.00e-19	90.50
IUUC-Lpe-051132	Leersia perrieri	51.87	3.00e-86	311.00
IUUC-Loc-052427	Lepisosteus oculatus	29.64	5.00e-34	138.00
IUUC-Laf-053758	Loxodonta africana	30.60	2.00e-27	116.00
IUUC-Mcc-055682	Macaca mulatta	34.22	9.00e-36	144.00
IUUC-Meu-056004	Macropus eugenii	31.16	1.00e-20	94.00
IUUC-Mtr-058392	Medicago truncatula	62.79	9.00e-113	399.00
IUUC-Mga-059466	Meleagris gallopavo	32.13	1.00e-34	140.00
IUUC-Mmr-060890	Microcebus murinus	29.77	2.00e-22	99.80
IUUC-Mdo-062122	Monodelphis domestica	32.46	2.00e-34	139.00
IUUC-Mmu-063176	Mus musculus	32.53	3.00e-33	136.00
IUUC-Mac-064858	Musa acuminata	69.29	6.00e-41	160.00
IUUC-Mpu-065927	Mustela putorius furo	33.33	3.00e-36	145.00
IUUC-Mlu-067079	Myotis lucifugus	33.98	2.00e-39	156.00
IUUC-Nle-070180	Nomascus leucogenys	34.22	9.00e-36	144.00
IUUC-Opr-070847	Ochotona princeps	33.33	2.00e-21	97.10
IUUC-Ont-071846	Oreochromis niloticus	33.01	4.00e-33	135.00
IUUC-Oan-072783	Ornithorhynchus anatinus	34.84	8.00e-32	130.00
IUUC-Ocu-074527	Oryctolagus cuniculus	32.62	6.00e-35	141.00
IUUC-Oba-075256	Oryza barthii	52.47	2.00e-81	295.00
IUUC-Obr-076302	Oryza brachyantha	52.71	5.00e-86	311.00
IUUC-Ogl-077097	Oryza glaberrima	51.93	3.00e-90	325.00
IUUC-Ogu-078570	Oryza glumaepatula	53.28	2.00e-86	312.00
IUUC-Oin-079244	Oryza indica	51.93	7.00e-90	324.00
IUUC-Olo-080484	Oryza longistaminata	52.15	4.00e-60	224.00
IUUC-Ome-081814	Oryza meridionalis	51.49	8.00e-92	330.00
IUUC-Oni-082057	Oryza nivara	53.28	4.00e-86	311.00
IUUC-Opu-084176	Oryza punctata	52.68	1.00e-86	313.00
IUUC-Oru-084618	Oryza rufipogon	53.28	2.00e-86	312.00
IUUC-Osa-085602	Oryza sativa	52.90	2.00e-87	315.00
IUUC-Ola-086707	Oryzias latipes	31.02	3.00e-24	105.00
IUUC-Olu-087811	Ostreococcus lucimarinus	40.28	1.00e-46	179.00
IUUC-Oga-088560	Otolemur garnettii	30.23	7.00e-23	101.00
IUUC-Oar-090348	Ovis aries	31.91	2.00e-36	146.00
IUUC-Ptr-091060	Pan troglodytes	34.22	9.00e-36	144.00
IUUC-Pan-091855	Papio anubis	32.62	1.00e-32	134.00
IUUC-Psi-093505	Pelodiscus sinensis	33.49	2.00e-35	143.00
IUUC-Pma-094612	Petromyzon marinus	30.70	2.00e-18	87.00
IUUC-Ppa-095431	Physcomitrella patens	54.22	2.00e-55	209.00
IUUC-Pfo-097396	Poecilia formosa	32.05	2.00e-38	153.00
IUUC-Pab-098591	Pongo abelii	34.22	9.00e-36	144.00
IUUC-Pop-099661	Populus trichocarpa	48.49	4.00e-89	321.00
IUUC-Pca-101029	Procavia capensis	35.50	6.00e-32	131.00
IUUC-Ppe-101495	Prunus persica	64.38	5.00e-142	497.00
IUUC-Pva-102244	Pteropus vampyrus	33.17	2.00e-35	143.00
IUUC-Rno-105861	Rattus norvegicus	33.02	8.00e-22	98.20
IUUC-Sha-107045	Sarcophilus harrisii	32.37	7.00e-35	141.00
IUUC-Smo-109325	Selaginella moellendorffii	44.93	1.00e-64	239.00
IUUC-Sit-110624	Setaria italica	49.89	6.00e-84	304.00
IUUC-Sly-110865	Solanum lycopersicum	85.71	4.00e-30	122.00
IUUC-Stu-112433	Solanum tuberosum	58.66	5.00e-115	407.00
IUUC-Sar-113169	Sorex araneus	36.45	5.00e-31	128.00
IUUC-Sbi-114305	Sorghum bicolor	50.85	2.00e-86	312.00
IUUC-Ssc-115766	Sus scrofa	33.65	6.00e-37	148.00
IUUC-Tgu-117280	Taeniopygia guttata	32.77	2.00e-32	133.00
IUUC-Tru-117732	Takifugu rubripes	31.97	3.00e-35	142.00
IUUC-Tsy-119624	Tarsius syrichta	32.56	6.00e-22	98.20
IUUC-Tni-119852	Tetraodon nigroviridis	31.98	3.00e-32	132.00
IUUC-Tca-121865	Theobroma cacao	69.20	2.00e-136	478.00
IUUC-Tae-123984	Triticum aestivum	50.54	8.00e-87	313.00
IUUC-Tur-126237	Triticum urartu	49.60	9.00e-78	283.00
IUUC-Tbe-128148	Tupaia belangeri	31.78	3.00e-21	95.90
IUUC-Ttr-128793	Tursiops truncatus	32.69	7.00e-33	134.00
IUUC-Vpa-130625	Vicugna pacos	34.20	2.00e-29	122.00
IUUC-Vvi-131312	Vitis vinifera	65.35	3.00e-132	464.00
IUUC-Xtr-131790	Xenopus tropicalis	32.01	1.00e-32	134.00
IUUC-Xma-133377	Xiphophorus maculatus	33.49	4.00e-39	155.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence