iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066219

Ensembl Protein ID

ENSMPUP00000000869.1

UniProt Accession

M3XP69; M3XP69_MUSPF

Genbank Protein ID

ENSMPUP00000000869

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01085687

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000000873.1	ENSMPUT00000000885.1	ENSMPUP00000000869.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.30e-08	34.8	16	85
E3 activity/RING/RING	1.30e-06	28.9	21	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawcee 71
            ee+lC++ ++++rd v+l +G+ + r ++ ++ + +   tcPv++ + +  dl  n+tl +l+++ + e
   Q: 16   KEELLCAVCYDPFRDAVTLRCGHNFCRVCVTRCWEVQVApTCPVCKDRAALADLRTNHTLNNLVEKLLRE 85
           689******************************9776666***********************9987765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f++ C+  +w     + + + +CP+C+
   Q: 21   CAVCYDPFRD-AVTLRCGHNFCRVCVtRCW-----EVQVAPTCPVCK 61
           ********99.999***********99999.....789999*****6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MESGPAASPG PSRSFKEELL CAVCYDPFRD AVTLRCGHNF CRVCVTRCWE VQVAPTCPVC 60
KDRAALADLR TNHTLNNLVE KLLREEAEGA RWEGHRSPRL CRPHRGQFSL FCLDDKELLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTCGG GTCCCGCGGC GTCCCCCGGG CCTTCCCGCT CCTTCAAGGA GGAGCTGCTC 60
TGTGCGGTCT GCTACGACCC CTTCCGCGAC GCCGTGACTC TGCGCTGTGG GCACAACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	96.75	0.00e+00	988.00
IUUC-Apl-003958	Anas platyrhynchos	53.75	3.00e-130	458.00
IUUC-Aca-005199	Anolis carolinensis	47.31	1.00e-124	439.00
IUUC-Ame-011964	Astyanax mexicanus	35.14	8.00e-72	264.00
IUUC-Bta-013359	Bos taurus	91.28	0.00e+00	917.00
IUUC-Cja-018900	Callithrix jacchus	75.40	0.00e+00	767.00
IUUC-Cfa-020685	Canis familiaris	96.35	0.00e+00	988.00
IUUC-Cpo-022253	Cavia porcellus	77.89	0.00e+00	773.00
IUUC-Csa-023777	Chlorocebus sabaeus	89.86	0.00e+00	925.00
IUUC-Dre-028296	Danio rerio	31.72	2.00e-69	256.00
IUUC-Dno-029065	Dasypus novemcinctus	86.17	0.00e+00	906.00
IUUC-Dor-030248	Dipodomys ordii	61.60	4.00e-98	350.00
IUUC-Ete-033183	Echinops telfairi	76.47	0.00e+00	751.00
IUUC-Eca-033263	Equus caballus	91.83	0.00e+00	828.00
IUUC-Eeu-034699	Erinaceus europaeus	82.43	5.00e-119	421.00
IUUC-Fca-036366	Felis catus	94.32	0.00e+00	969.00
IUUC-Fal-037257	Ficedula albicollis	55.74	2.00e-156	545.00
IUUC-Gmo-038512	Gadus morhua	34.72	6.00e-68	251.00
IUUC-Gga-041125	Gallus gallus	55.10	2.00e-107	382.00
IUUC-Gac-041608	Gasterosteus aculeatus	31.73	2.00e-63	236.00
IUUC-Ggo-045233	Gorilla gorilla	89.87	1.00e-171	595.00
IUUC-Hsa-046042	Homo sapiens	89.86	0.00e+00	926.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	88.82	0.00e+00	895.00
IUUC-Laf-054322	Loxodonta africana	91.00	0.00e+00	914.00
IUUC-Mcc-055555	Macaca mulatta	87.78	0.00e+00	905.00
IUUC-Meu-055900	Macropus eugenii	78.78	0.00e+00	787.00
IUUC-Mga-059380	Meleagris gallopavo	55.62	1.00e-105	376.00
IUUC-Mmr-061296	Microcebus murinus	88.84	0.00e+00	907.00
IUUC-Mdo-062811	Monodelphis domestica	78.41	0.00e+00	788.00
IUUC-Mmu-063718	Mus musculus	78.81	0.00e+00	802.00
IUUC-Mlu-067033	Myotis lucifugus	86.18	0.00e+00	893.00
IUUC-Nle-069806	Nomascus leucogenys	89.80	0.00e+00	863.00
IUUC-Opr-070248	Ochotona princeps	77.98	0.00e+00	759.00
IUUC-Ont-072047	Oreochromis niloticus	34.03	2.00e-68	253.00
IUUC-Oan-073364	Ornithorhynchus anatinus	68.83	2.00e-97	348.00
IUUC-Ocu-074572	Oryctolagus cuniculus	90.85	0.00e+00	937.00
IUUC-Oga-088378	Otolemur garnettii	86.21	0.00e+00	879.00
IUUC-Oar-089516	Ovis aries	90.83	0.00e+00	906.00
IUUC-Ptr-091313	Pan troglodytes	89.86	0.00e+00	926.00
IUUC-Pan-092877	Papio anubis	90.06	0.00e+00	927.00
IUUC-Psi-093928	Pelodiscus sinensis	59.58	7.00e-165	573.00
IUUC-Pfo-096690	Poecilia formosa	34.74	5.00e-71	261.00
IUUC-Pab-098624	Pongo abelii	89.45	0.00e+00	918.00
IUUC-Pca-100469	Procavia capensis	83.09	0.00e+00	834.00
IUUC-Pva-103227	Pteropus vampyrus	91.48	0.00e+00	938.00
IUUC-Rno-105778	Rattus norvegicus	78.60	0.00e+00	802.00
IUUC-Sha-107392	Sarcophilus harrisii	68.61	0.00e+00	673.00
IUUC-Sar-113297	Sorex araneus	71.32	2.00e-51	196.00
IUUC-Ssc-115739	Sus scrofa	92.49	0.00e+00	923.00
IUUC-Tru-117718	Takifugu rubripes	32.00	4.00e-63	235.00
IUUC-Tbe-127926	Tupaia belangeri	75.25	0.00e+00	707.00
IUUC-Ttr-129293	Tursiops truncatus	93.31	0.00e+00	952.00
IUUC-Vpa-130379	Vicugna pacos	92.28	5.00e-163	566.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence