iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090077

Ensembl Protein ID

ENSOARP00000018132.1

UniProt Accession

W5Q5Z2; W5Q5Z2_SHEEP

Genbank Protein ID

ENSOARP00000018132

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01052339

Gene Name

UBE2E3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000016885.1	ENSOART00000018388.1	ENSOARP00000018132.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.90e-50	169.1	94	229

Active Site

Position(s)	Description	Evidence
174	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel+e++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f++dYPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 94   RIQKELAEITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 179
           99**********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 180  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQ 229
           ********************************************999875 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MLLVYFFRLT FPFFPRFFLK SFPRNNFTKM SSDRQRSDDE SPSTSSGSSD ADQRDPAAPE 60
PEEQEERKPS ATQQKKNTKL SSKTTAKLST SAKRIQKELA EITLDPPPNC SAGPKGDNIY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCCGGCCG CGGCTCGCCT CGGCGGGCGC GGAAATTTGC TGCACTTCTT GAGGCTTTGT 60
TTGTTTGTTT TTGCTCTGAA ATTTTTTTTT TTTTTGGTTA TTTTGGACAA AATGTCGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000463	Aegilops tauschii	64.34	1.00e-52	201.00
IUUC-Apl-003415	Anas platyrhynchos	99.52	3.00e-89	320.00
IUUC-Aca-005276	Anolis carolinensis	94.57	9.00e-91	325.00
IUUC-Ame-011419	Astyanax mexicanus	96.50	1.00e-81	295.00
IUUC-Bta-012796	Bos taurus	98.55	4.00e-86	310.00
IUUC-Cja-019670	Callithrix jacchus	100.00	3.00e-89	320.00
IUUC-Cfa-021171	Canis familiaris	100.00	3.00e-89	320.00
IUUC-Cre-022791	Chlamydomonas reinhardtii	80.00	2.00e-71	260.00
IUUC-Csa-023464	Chlorocebus sabaeus	99.52	8.00e-89	319.00
IUUC-Cme-027286	Cyanidioschyzon merolae	72.62	2.00e-70	257.00
IUUC-Dre-027376	Danio rerio	100.00	1.00e-83	302.00
IUUC-Dno-029505	Dasypus novemcinctus	95.36	3.00e-75	273.00
IUUC-Ete-032812	Echinops telfairi	100.00	9.00e-84	301.00
IUUC-Eca-033312	Equus caballus	100.00	3.00e-89	320.00
IUUC-Eeu-035232	Erinaceus europaeus	100.00	9.00e-84	301.00
IUUC-Fal-036688	Ficedula albicollis	99.52	3.00e-89	320.00
IUUC-Gga-040613	Gallus gallus	99.52	3.00e-89	320.00
IUUC-Ggo-045068	Gorilla gorilla	96.14	2.00e-83	301.00
IUUC-Hsa-046464	Homo sapiens	100.00	3.00e-89	320.00
IUUC-Itr-048624	Ictidomys tridecemlineatus	100.00	6.00e-74	268.00
IUUC-Loc-052492	Lepisosteus oculatus	96.19	1.00e-87	315.00
IUUC-Laf-054416	Loxodonta africana	100.00	3.00e-89	320.00
IUUC-Mcc-055754	Macaca mulatta	99.52	8.00e-89	319.00
IUUC-Mtr-058214	Medicago truncatula	60.26	2.00e-54	204.00
IUUC-Mga-059436	Meleagris gallopavo	99.52	3.00e-89	320.00
IUUC-Mmr-060893	Microcebus murinus	99.03	1.00e-92	331.00
IUUC-Mdo-063010	Monodelphis domestica	100.00	3.00e-89	320.00
IUUC-Mmu-063493	Mus musculus	100.00	3.00e-89	320.00
IUUC-Mpu-065789	Mustela putorius furo	100.00	3.00e-89	320.00
IUUC-Mlu-066934	Myotis lucifugus	99.52	6.00e-89	319.00
IUUC-Nle-069930	Nomascus leucogenys	100.00	3.00e-89	320.00
IUUC-Opr-070917	Ochotona princeps	94.74	1.00e-59	220.00
IUUC-Ocu-074769	Oryctolagus cuniculus	97.10	3.00e-85	307.00
IUUC-Olu-087783	Ostreococcus lucimarinus	77.86	3.00e-65	240.00
IUUC-Oga-088760	Otolemur garnettii	100.00	3.00e-89	320.00
IUUC-Ptr-091596	Pan troglodytes	97.10	4.00e-84	303.00
IUUC-Pan-092142	Papio anubis	99.52	8.00e-89	319.00
IUUC-Psi-093471	Pelodiscus sinensis	99.52	3.00e-89	320.00
IUUC-Ppa-095789	Physcomitrella patens	78.38	7.00e-69	252.00
IUUC-Pab-098675	Pongo abelii	100.00	3.00e-89	320.00
IUUC-Pop-099024	Populus trichocarpa	65.03	2.00e-57	214.00
IUUC-Pca-100467	Procavia capensis	100.00	3.00e-89	320.00
IUUC-Ppe-101314	Prunus persica	59.72	3.00e-53	200.00
IUUC-Pva-103205	Pteropus vampyrus	100.00	3.00e-89	320.00
IUUC-Rno-105806	Rattus norvegicus	97.32	9.00e-86	308.00
IUUC-Smo-108957	Selaginella moellendorffii	69.74	7.00e-63	232.00
IUUC-Sly-111200	Solanum lycopersicum	61.54	3.00e-54	204.00
IUUC-Sar-113672	Sorex araneus	100.00	3.00e-89	320.00
IUUC-Tgu-116892	Taeniopygia guttata	99.52	3.00e-89	320.00
IUUC-Tru-118527	Takifugu rubripes	96.48	7.00e-81	292.00
IUUC-Tsy-119046	Tarsius syrichta	100.00	1.00e-88	318.00
IUUC-Tni-119832	Tetraodon nigroviridis	96.43	2.00e-80	291.00
IUUC-Tca-121777	Theobroma cacao	63.19	3.00e-55	207.00
IUUC-Tbe-127690	Tupaia belangeri	100.00	6.00e-86	309.00
IUUC-Ttr-128849	Tursiops truncatus	100.00	3.00e-89	320.00
IUUC-Vvi-131190	Vitis vinifera	61.84	1.00e-55	208.00
IUUC-Xtr-132173	Xenopus tropicalis	99.04	2.00e-89	321.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence