iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	82.34	0.00e+00	1659.00	IUUC-Hsa-046254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPA KSSTQGLLVG PNSDTSSLDA KVLGNKDASR 60
QQQMRATPKF GPYQKALREI RYSLLPFANE SGTSAAAEVN RQMLQELVNA GCDQEMAGRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGTGATGG TCTTCAAAAT GAAAACTCTG GAAAATTTTA GGTTCTCTTT AGGAGCTACA 60
GAAATTGAAG GAAGTTGTTC TGGAAGCATG TTTACAACTC ACTGACAGTA TTACCTGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0046620--P:regulation of organ growth

KEGG

rno:305922

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	78.43	0.00e+00	1657.00
IUUC-Apl-003521	Anas platyrhynchos	68.68	0.00e+00	1122.00
IUUC-Aca-004995	Anolis carolinensis	68.44	0.00e+00	1385.00
IUUC-Ame-011481	Astyanax mexicanus	60.60	0.00e+00	1194.00
IUUC-Bta-012618	Bos taurus	84.11	0.00e+00	984.00
IUUC-Cja-019430	Callithrix jacchus	82.29	0.00e+00	1650.00
IUUC-Cfa-020687	Canis familiaris	77.56	0.00e+00	1618.00
IUUC-Cpo-021985	Cavia porcellus	84.40	0.00e+00	1070.00
IUUC-Csa-023534	Chlorocebus sabaeus	92.13	0.00e+00	949.00
IUUC-Dre-027538	Danio rerio	60.25	0.00e+00	1215.00
IUUC-Dno-029126	Dasypus novemcinctus	76.29	0.00e+00	1617.00
IUUC-Dor-030172	Dipodomys ordii	80.19	0.00e+00	1438.00
IUUC-Eca-033868	Equus caballus	77.02	0.00e+00	1627.00
IUUC-Eeu-034881	Erinaceus europaeus	66.39	0.00e+00	1255.00
IUUC-Fca-036203	Felis catus	75.19	0.00e+00	1541.00
IUUC-Fal-036668	Ficedula albicollis	69.98	0.00e+00	1466.00
IUUC-Gmo-039195	Gadus morhua	83.88	0.00e+00	772.00
IUUC-Gac-041789	Gasterosteus aculeatus	82.72	0.00e+00	865.00
IUUC-Ggo-044904	Gorilla gorilla	78.91	0.00e+00	1574.00
IUUC-Hsa-046254	Homo sapiens	81.06	0.00e+00	1585.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	82.51	0.00e+00	1488.00
IUUC-Lch-050079	Latimeria chalumnae	64.16	0.00e+00	1352.00
IUUC-Loc-052265	Lepisosteus oculatus	80.96	0.00e+00	870.00
IUUC-Laf-053806	Loxodonta africana	79.15	0.00e+00	1658.00
IUUC-Mcc-055253	Macaca mulatta	80.29	0.00e+00	1596.00
IUUC-Meu-056509	Macropus eugenii	80.88	0.00e+00	778.00
IUUC-Mga-059600	Meleagris gallopavo	69.63	0.00e+00	1483.00
IUUC-Mmr-061586	Microcebus murinus	80.67	0.00e+00	1603.00
IUUC-Mdo-062126	Monodelphis domestica	69.34	0.00e+00	1446.00
IUUC-Mmu-063164	Mus musculus	93.87	0.00e+00	1920.00
IUUC-Mpu-065992	Mustela putorius furo	77.80	0.00e+00	1651.00
IUUC-Mlu-067728	Myotis lucifugus	74.95	0.00e+00	1470.00
IUUC-Nle-069546	Nomascus leucogenys	80.17	0.00e+00	1586.00
IUUC-Opr-070872	Ochotona princeps	80.26	0.00e+00	1573.00
IUUC-Ont-072296	Oreochromis niloticus	84.54	0.00e+00	907.00
IUUC-Ocu-074068	Oryctolagus cuniculus	81.42	0.00e+00	1597.00
IUUC-Ola-086756	Oryzias latipes	82.55	0.00e+00	903.00
IUUC-Oga-089066	Otolemur garnettii	81.81	0.00e+00	1645.00
IUUC-Oar-090416	Ovis aries	82.81	0.00e+00	979.00
IUUC-Ptr-091247	Pan troglodytes	80.60	0.00e+00	1592.00
IUUC-Pan-092438	Papio anubis	80.29	0.00e+00	1596.00
IUUC-Psi-093920	Pelodiscus sinensis	69.31	0.00e+00	1477.00
IUUC-Pfo-096334	Poecilia formosa	83.84	0.00e+00	882.00
IUUC-Pab-098452	Pongo abelii	81.23	0.00e+00	1615.00
IUUC-Pca-101081	Procavia capensis	72.27	0.00e+00	1504.00
IUUC-Sha-106917	Sarcophilus harrisii	71.00	0.00e+00	1484.00
IUUC-Sar-113711	Sorex araneus	75.54	0.00e+00	1420.00
IUUC-Tgu-116553	Taeniopygia guttata	72.99	0.00e+00	1508.00
IUUC-Tru-118069	Takifugu rubripes	83.10	0.00e+00	887.00
IUUC-Tni-120617	Tetraodon nigroviridis	80.50	0.00e+00	877.00
IUUC-Ttr-129256	Tursiops truncatus	68.36	0.00e+00	1335.00
IUUC-Xtr-132593	Xenopus tropicalis	67.21	0.00e+00	1384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence