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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-045750
Ensembl Protein ID ENSP00000454783.1
UniProt Accession Q9UQ03; A8K0W3; O94767; Q8TAN1; COR2B_HUMAN
Genbank Protein ID BAA36341.1; BAF82367.1; AAH26335.1; BAA76769.1
Protein Name Coronin-2B; Coronin-like protein C; Protein FC96
Genbank Nucleotide ID AB010098; AK289678; AC090734; AB023142
Gene Name CORO2B; KIAA0925
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000103647.12 ENST00000566799.5 ENSP00000454783.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACmiRecords
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
InWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.50e-16 60.3 85 122
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvl 35
           gH++ v ++++    + ++++s+s D ++++W++ +g l
   Q: 85   GHQGNVLDIKWnpfiD-NIIASCSEDTSVRIWEIPEGGL 122
           8**********98854.9***************887765 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Belongs to the WD repeat coronin family.
 Belongs to the WD repeat coronin family.
Protein Sequence
(Fasta)
MTVTKMSWRP QYRSSKFRNV YGKVANREHC FDGIPITKNV HDNHFCAVNT RFLAIVTESA 60
GGGSFLVIPL EQTGRIEPNY PKVCGHQGNV LDIKWNPFID NIIASCSEDT SVRIWEIPEG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045750|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGGCCCTCT CCCTCTCTCC CTTTCTTCCT GCCTCGCCTT CCTGCGGCGA AGGAGGCTCA 60
TCTATTATAA ATGCACATTC GGGGCTGACA TCAGCGACGA GCGGCGGGCG AGCGCCGACG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045750|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0009--Actin-binding
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027339--CORO2B
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08953--DUF1899
PF00400--WD40
SMART

SM01166--DUF1899
SM00320--WD40
Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0003779--F:actin binding
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
KEGG hsa:10391
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002018 Ailuropoda melanoleuca 91.19 0.00e+00 925.00
IUUC-Apl-003786 Anas platyrhynchos 87.11 0.00e+00 919.00
IUUC-Aca-004750 Anolis carolinensis 92.28 0.00e+00 943.00
IUUC-Ame-011201 Astyanax mexicanus 73.67 0.00e+00 759.00
IUUC-Bta-012392 Bos taurus 96.84 0.00e+00 898.00
IUUC-Cja-019618 Callithrix jacchus 100.00 0.00e+00 845.00
IUUC-Cfa-020090 Canis familiaris 98.95 0.00e+00 982.00
IUUC-Cpo-021875 Cavia porcellus 98.12 0.00e+00 979.00
IUUC-Csa-023813 Chlorocebus sabaeus 99.58 0.00e+00 995.00
IUUC-Dre-028472 Danio rerio 87.31 0.00e+00 872.00
IUUC-Dno-029558 Dasypus novemcinctus 98.33 0.00e+00 984.00
IUUC-Dor-031144 Dipodomys ordii 97.05 0.00e+00 934.00
IUUC-Ete-032835 Echinops telfairi 88.43 0.00e+00 791.00
IUUC-Eca-033620 Equus caballus 99.37 0.00e+00 984.00
IUUC-Fca-035729 Felis catus 98.74 0.00e+00 984.00
IUUC-Fal-037197 Ficedula albicollis 92.41 0.00e+00 939.00
IUUC-Gmo-039540 Gadus morhua 86.53 0.00e+00 856.00
IUUC-Gga-040455 Gallus gallus 94.51 0.00e+00 950.00
IUUC-Gac-042218 Gasterosteus aculeatus 85.05 0.00e+00 876.00
IUUC-Ggo-044922 Gorilla gorilla 99.58 0.00e+00 990.00
IUUC-Itr-048866 Ictidomys tridecemlineatus 99.37 0.00e+00 983.00
IUUC-Lch-049567 Latimeria chalumnae 81.40 0.00e+00 883.00
IUUC-Loc-052145 Lepisosteus oculatus 92.47 0.00e+00 865.00
IUUC-Laf-054013 Loxodonta africana 98.32 0.00e+00 974.00
IUUC-Mcc-055230 Macaca mulatta 95.75 0.00e+00 973.00
IUUC-Meu-056208 Macropus eugenii 84.94 4.00e-154 537.00
IUUC-Mga-059825 Meleagris gallopavo 88.27 0.00e+00 920.00
IUUC-Mmr-060944 Microcebus murinus 98.74 0.00e+00 985.00
IUUC-Mdo-061845 Monodelphis domestica 89.22 0.00e+00 920.00
IUUC-Mmu-064197 Mus musculus 98.12 0.00e+00 988.00
IUUC-Mpu-065993 Mustela putorius furo 98.33 0.00e+00 982.00
IUUC-Mlu-067427 Myotis lucifugus 90.06 0.00e+00 875.00
IUUC-Nle-069666 Nomascus leucogenys 98.80 0.00e+00 848.00
IUUC-Opr-070358 Ochotona princeps 98.53 0.00e+00 977.00
IUUC-Ont-072071 Oreochromis niloticus 85.86 0.00e+00 862.00
IUUC-Oan-073064 Ornithorhynchus anatinus 90.08 0.00e+00 919.00
IUUC-Ocu-074888 Oryctolagus cuniculus 98.04 0.00e+00 837.00
IUUC-Ola-086733 Oryzias latipes 78.72 0.00e+00 861.00
IUUC-Oga-088842 Otolemur garnettii 99.79 0.00e+00 987.00
IUUC-Oar-089753 Ovis aries 99.38 0.00e+00 993.00
IUUC-Ptr-090933 Pan troglodytes 99.79 0.00e+00 992.00
IUUC-Pan-092127 Papio anubis 99.76 0.00e+00 847.00
IUUC-Psi-092947 Pelodiscus sinensis 94.30 0.00e+00 950.00
IUUC-Pma-094375 Petromyzon marinus 74.04 1.00e-135 475.00
IUUC-Pfo-096261 Poecilia formosa 85.16 0.00e+00 746.00
IUUC-Pab-098546 Pongo abelii 100.00 0.00e+00 912.00
IUUC-Pca-100133 Procavia capensis 98.96 2.00e-172 598.00
IUUC-Pva-102257 Pteropus vampyrus 99.26 0.00e+00 844.00
IUUC-Rno-105827 Rattus norvegicus 98.33 0.00e+00 989.00
IUUC-Sha-106730 Sarcophilus harrisii 96.87 0.00e+00 973.00
IUUC-Ssc-115774 Sus scrofa 95.17 0.00e+00 972.00
IUUC-Tru-117702 Takifugu rubripes 75.96 0.00e+00 832.00
IUUC-Tni-120573 Tetraodon nigroviridis 77.69 0.00e+00 847.00
IUUC-Tbe-127746 Tupaia belangeri 88.86 0.00e+00 686.00
IUUC-Ttr-128935 Tursiops truncatus 99.07 0.00e+00 889.00
IUUC-Xtr-132098 Xenopus tropicalis 85.18 0.00e+00 880.00
Created Date 25-Jun-2017

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