iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033407

Ensembl Protein ID

ENSECAP00000012384.1

UniProt Accession

F7CSW5; F7CSW5_HORSE

Protein Name

Uncharacterized protein

Gene Name

SLX4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000014662.1	ENSECAT00000015411.1	ENSECAP00000012384.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/UBZ	64.98	0.00e+00	1392.00	IUUC-Hsa-047035

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MEVGPQLLLQ AVRLQTAQAE GSCSTPLSSF SNHVGGLKRK GATNKKEPKK RRKVNEPEAP 60
SEDLLVAMAL SRSEMEQQAV PATLRLGNTF SEKTRPGAEK KSRKKKALAS APQLLVQDSE 120

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Nucleotide Sequence
(Fasta)

AGAGGCTGCT CCTGACAGCA TCTCCCAGCC GCCTCCTTCC TGTCTGACTG CGATTGTGCC 60
AAGTCCCTCC AAACCCCGGA CGGCAGAGCT GGTCCTACAG CGAATGCAGC AGTTCAAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR018574--Structure-sp_endonuc_su_Slx4

PROSITE

PS50097--BTB

Pfam

PF00651--BTB
PF09494--Slx4

SMART

SM00225--BTB

Gene Ontology

GO:0030054--C:cell junction
GO:0005829--C:cytosol
GO:0070522--C:ERCC4-ERCC1 complex
GO:0048476--C:Holliday junction resolvase complex
GO:0000790--C:nuclear chromatin
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0033557--C:Slx1-Slx4 complex
GO:0048257--F:3'-flap endonuclease activity
GO:0017108--F:5'-flap endonuclease activity
GO:0008821--F:crossover junction endodeoxyribonuclease activity
GO:0008047--F:enzyme activator activity
GO:0010792--P:DNA double-strand break processing involved in repair via single-strand annealing
GO:0006260--P:DNA replication
GO:0000724--P:double-strand break repair via homologous recombination
GO:0036297--P:interstrand cross-link repair
GO:0000706--P:meiotic DNA double-strand break processing
GO:1904357--P:negative regulation of telomere maintenance via telomere lengthening
GO:0006289--P:nucleotide-excision repair
GO:1904431--P:positive regulation of t-circle formation
GO:0000712--P:resolution of meiotic recombination intermediates
GO:0072429--P:response to intra-S DNA damage checkpoint signaling
GO:0090656--P:t-circle formation
GO:0061820--P:telomeric D-loop disassembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001225	Ailuropoda melanoleuca	73.15	0.00e+00	1565.00
IUUC-Apl-003261	Anas platyrhynchos	36.97	4.00e-122	433.00
IUUC-Aca-004455	Anolis carolinensis	74.07	3.00e-19	85.90
IUUC-Acl-008026	Aspergillus clavatus	24.41	5.10e-01	30.00
IUUC-Bta-013472	Bos taurus	64.05	0.00e+00	1268.00
IUUC-Cja-019406	Callithrix jacchus	63.97	0.00e+00	1287.00
IUUC-Cfa-020129	Canis familiaris	69.77	0.00e+00	1370.00
IUUC-Cpo-021944	Cavia porcellus	58.65	0.00e+00	1186.00
IUUC-Csa-023941	Chlorocebus sabaeus	62.15	0.00e+00	775.00
IUUC-Cho-024847	Choloepus hoffmanni	65.49	8.00e-131	462.00
IUUC-Cin-025405	Ciona intestinalis	40.74	4.00e-07	48.90
IUUC-Csv-025916	Ciona savignyi	35.59	1.00e-07	50.10
IUUC-Dre-027764	Danio rerio	31.98	3.00e-38	154.00
IUUC-Dno-030083	Dasypus novemcinctus	57.89	0.00e+00	1087.00
IUUC-Dor-031129	Dipodomys ordii	53.02	0.00e+00	898.00
IUUC-Ete-032536	Echinops telfairi	46.51	2.00e-125	444.00
IUUC-Eeu-034473	Erinaceus europaeus	51.89	8.00e-73	269.00
IUUC-Fca-035730	Felis catus	68.83	0.00e+00	1550.00
IUUC-Fal-036850	Ficedula albicollis	34.84	3.00e-141	497.00
IUUC-Gmo-038677	Gadus morhua	45.63	6.00e-33	135.00
IUUC-Gga-041088	Gallus gallus	45.61	2.00e-98	354.00
IUUC-Gac-041824	Gasterosteus aculeatus	46.38	4.00e-13	67.80
IUUC-Ggo-045642	Gorilla gorilla	64.41	0.00e+00	1313.00
IUUC-Hsa-047035	Homo sapiens	64.82	0.00e+00	1332.00
IUUC-Itr-049010	Ictidomys tridecemlineatus	63.31	0.00e+00	1288.00
IUUC-Kpa-049328	Komagataella pastoris	30.00	2.40e-02	33.90
IUUC-Lch-050364	Latimeria chalumnae	39.90	2.00e-93	337.00
IUUC-Loc-052423	Lepisosteus oculatus	40.57	5.00e-44	174.00
IUUC-Laf-053910	Loxodonta africana	60.92	0.00e+00	1269.00
IUUC-Mcc-055883	Macaca mulatta	65.27	0.00e+00	1401.00
IUUC-Meu-056224	Macropus eugenii	54.95	1.00e-102	368.00
IUUC-Mga-059880	Meleagris gallopavo	36.06	9.00e-141	495.00
IUUC-Mvi-060510	Microbotryum violaceum	34.55	4.00e-04	40.40
IUUC-Mmr-061715	Microcebus murinus	65.49	0.00e+00	1433.00
IUUC-Mdo-062426	Monodelphis domestica	44.43	0.00e+00	793.00
IUUC-Mmu-063947	Mus musculus	58.65	0.00e+00	1244.00
IUUC-Mpu-066184	Mustela putorius furo	69.24	0.00e+00	1552.00
IUUC-Mlu-067533	Myotis lucifugus	75.77	0.00e+00	1558.00
IUUC-Nle-069204	Nomascus leucogenys	64.44	0.00e+00	1338.00
IUUC-Opr-070377	Ochotona princeps	65.61	4.00e-166	579.00
IUUC-Ont-072551	Oreochromis niloticus	32.70	7.00e-45	176.00
IUUC-Oan-073350	Ornithorhynchus anatinus	54.24	1.00e-43	170.00
IUUC-Ocu-074915	Oryctolagus cuniculus	56.66	0.00e+00	954.00
IUUC-Ola-087360	Oryzias latipes	45.12	3.00e-29	121.00
IUUC-Oga-089106	Otolemur garnettii	63.89	0.00e+00	1413.00
IUUC-Oar-089289	Ovis aries	65.17	0.00e+00	791.00
IUUC-Ptr-091469	Pan troglodytes	65.16	0.00e+00	1332.00
IUUC-Pan-091841	Papio anubis	65.19	0.00e+00	1379.00
IUUC-Psi-093842	Pelodiscus sinensis	48.95	4.00e-98	353.00
IUUC-Pma-094732	Petromyzon marinus	55.77	2.00e-09	55.10
IUUC-Pfo-097299	Poecilia formosa	39.01	1.00e-34	142.00
IUUC-Pab-098271	Pongo abelii	64.37	0.00e+00	1308.00
IUUC-Pca-100721	Procavia capensis	51.71	2.00e-173	604.00
IUUC-Pva-102276	Pteropus vampyrus	75.91	0.00e+00	1810.00
IUUC-Rno-105619	Rattus norvegicus	58.15	0.00e+00	1188.00
IUUC-Sha-106722	Sarcophilus harrisii	47.36	0.00e+00	820.00
IUUC-Sar-113673	Sorex araneus	62.04	2.00e-67	251.00
IUUC-Sre-115039	Sporisorium reilianum	33.96	3.00e-04	38.90
IUUC-Ssc-115383	Sus scrofa	66.41	0.00e+00	1259.00
IUUC-Tgu-117243	Taeniopygia guttata	52.01	6.00e-99	353.00
IUUC-Tru-118092	Takifugu rubripes	66.10	2.00e-17	82.80
IUUC-Tsy-119362	Tarsius syrichta	64.13	0.00e+00	668.00
IUUC-Tni-120380	Tetraodon nigroviridis	66.13	1.00e-17	82.80
IUUC-Tbe-127404	Tupaia belangeri	50.60	0.00e+00	759.00
IUUC-Ttr-128317	Tursiops truncatus	72.44	0.00e+00	1442.00
IUUC-Uma-129640	Ustilago maydis	38.18	1.00e-05	43.90
IUUC-Xtr-132533	Xenopus tropicalis	41.17	1.00e-62	235.00
IUUC-Xma-134059	Xiphophorus maculatus	36.78	8.00e-35	143.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence