iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053673

UUCD1 version

UUC-LoA-00977

Ensembl Protein ID

ENSLAFP00000000754.3

UniProt Accession

G3SMK3; G3SMK3_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBE2D1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000000901.3	ENSLAFT00000000902.3	ENSLAFP00000000754.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.90e-55	185.8	6	139
UBD/UBC-like/UBD_UBC	3.40e-82	273.7	8	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeee 90
           l +el++l++dpp+++sa+pv + dl++w+++i+Gp+d+ Y+ggvF l+++fp+dYPfkPPk+ f+tki+hPn+++nG++Cl+il+  +
   Q: 6    LLQELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILR--S 91
           579********************.9************************************************************9..* PP
   S: 91   kWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +Wspal+v++vllsi+sll++pnp++pl  ++a+++k+++e+y++++r
   Q: 92   QWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAR 139
           ********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 4    kelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaa 92
           +el+dl+rd++a++sa++v+ddlf+++ati+gppds+y+ggvfflt+++ptdypfkppk+af+tkiyhpninsngsicldilrsqws+a
   Q: 8    QELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPA 96
           79*************************************************************************************** PP
   S: 93   ltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           lt+skvlls+csll+d++pddplv++ia+iyk+dkeky+r+arewt
   Q: 97   LTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWT 142
           *********************************************8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

LNIFALLQEL SDLQRDPPAH CSAGPVGDDL FHWQATIMGP PDSAYQGGVF FLTVHFPTDY 60
PFKPPKIAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAAATATTT TTGCTTTGCT TCAGGAATTA AGTGACCTGC AACGTGATCC ACCTGCGCAC 60
TGTTCAGCAG GACCTGTGGG AGATGACCGT AAGCTTTGTT CTATTGCTAG GATTTTGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001563	Ailuropoda melanoleuca	99.29	3.00e-81	293.00
IUUC-Apl-003639	Anas platyrhynchos	100.00	2.00e-81	293.00
IUUC-Aca-005254	Anolis carolinensis	99.29	3.00e-81	293.00
IUUC-Bta-013467	Bos taurus	99.29	3.00e-81	293.00
IUUC-Cja-019302	Callithrix jacchus	99.29	3.00e-81	293.00
IUUC-Cfa-021087	Canis familiaris	99.29	3.00e-81	293.00
IUUC-Csa-023668	Chlorocebus sabaeus	99.29	3.00e-81	293.00
IUUC-Cho-024987	Choloepus hoffmanni	99.29	3.00e-81	293.00
IUUC-Dno-030067	Dasypus novemcinctus	99.29	3.00e-81	293.00
IUUC-Dor-030474	Dipodomys ordii	99.29	3.00e-81	293.00
IUUC-Ete-032540	Echinops telfairi	99.29	3.00e-81	293.00
IUUC-Eca-034167	Equus caballus	99.29	3.00e-81	293.00
IUUC-Gga-040873	Gallus gallus	99.29	3.00e-81	293.00
IUUC-Hsa-045951	Homo sapiens	99.29	3.00e-81	293.00
IUUC-Itr-048743	Ictidomys tridecemlineatus	99.29	3.00e-81	293.00
IUUC-Mcc-055719	Macaca mulatta	99.29	3.00e-81	293.00
IUUC-Mga-060138	Meleagris gallopavo	100.00	2.00e-81	293.00
IUUC-Mmr-061212	Microcebus murinus	99.29	3.00e-81	293.00
IUUC-Mdo-062402	Monodelphis domestica	95.86	2.00e-81	294.00
IUUC-Mmu-063779	Mus musculus	99.29	3.00e-81	293.00
IUUC-Mpu-065724	Mustela putorius furo	99.29	3.00e-81	293.00
IUUC-Mlu-067573	Myotis lucifugus	100.00	2.00e-81	293.00
IUUC-Nle-069950	Nomascus leucogenys	99.29	3.00e-81	293.00
IUUC-Oan-073149	Ornithorhynchus anatinus	94.56	2.00e-81	293.00
IUUC-Oga-088915	Otolemur garnettii	99.29	3.00e-81	293.00
IUUC-Oar-090418	Ovis aries	99.29	3.00e-81	293.00
IUUC-Ptr-091575	Pan troglodytes	99.29	3.00e-81	293.00
IUUC-Pan-092922	Papio anubis	99.29	3.00e-81	293.00
IUUC-Pab-098137	Pongo abelii	99.29	3.00e-81	293.00
IUUC-Pca-100678	Procavia capensis	99.29	3.00e-81	293.00
IUUC-Pva-102770	Pteropus vampyrus	99.29	3.00e-81	293.00
IUUC-Rno-106124	Rattus norvegicus	99.29	3.00e-81	293.00
IUUC-Sha-106489	Sarcophilus harrisii	97.95	4.00e-83	299.00
IUUC-Sar-113557	Sorex araneus	100.00	8.00e-81	291.00
IUUC-Tgu-117399	Taeniopygia guttata	97.89	4.00e-81	292.00
IUUC-Ttr-128363	Tursiops truncatus	99.29	3.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence