iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065724

Ensembl Protein ID

ENSMPUP00000010328.1

UniProt Accession

M3YG71; M3YG71_MUSPF

Genbank Protein ID

ENSMPUP00000010328

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01100972

Gene Name

UBE2D1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000010403.1	ENSMPUT00000010493.1	ENSMPUP00000010328.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.20e-56	190.3	5	139
UBD/UBC-like/UBD_UBC	2.70e-84	280.2	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + dl++w+++i+Gp+d+ Y+ggvF l+++fp+dYPfkPPk+ f+tki+hPn+++nG++Cl+il+  
   Q: 5    RIQKELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILR-- 90
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal+v++vllsi+sll++pnp++pl  ++a+++k+++e+y++++r
   Q: 91   SQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel+dl+rd++a++sa++v+ddlf+++ati+gppds+y+ggvfflt+++ptdypfkppk+af+tkiyhpninsngsicldilrsqw
   Q: 5    RIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv++ia+iyk+dkeky+r+arewt
   Q: 94   SPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWT 142
           ************************************************8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MALKRIQKEL SDLQRDPPAH CSAGPVGDDL FHWQATIMGP PDSAYQGGVF FLTVHFPTDY 60
PFKPPKIAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGGCGCAG GCTCCTTCCC AGAAGCAAAA GCGGAAACAA AAGAGTCTTG CCGGCGTCCC 60
CGCCCGCACA CTCGCGCACA CTCGCGCTCG GGCGCACACT GAGCAGGCAC TGGCGCCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	76.19	4.00e-68	249.00
IUUC-Aml-001563	Ailuropoda melanoleuca	100.00	9.00e-86	308.00
IUUC-Atr-002782	Amborella trichopoda	77.55	7.00e-69	252.00
IUUC-Apl-003639	Anas platyrhynchos	99.29	4.00e-81	292.00
IUUC-Aca-005254	Anolis carolinensis	100.00	9.00e-86	308.00
IUUC-Aly-006221	Arabidopsis lyrata	78.23	2.00e-68	251.00
IUUC-Ath-007224	Arabidopsis thaliana	76.19	2.00e-68	251.00
IUUC-Ago-007967	Ashbya gossypii	78.91	9.00e-70	254.00
IUUC-Ani-009401	Aspergillus nidulans	78.91	4.00e-70	256.00
IUUC-Ame-011566	Astyanax mexicanus	94.56	6.00e-81	292.00
IUUC-Bta-013467	Bos taurus	100.00	9.00e-86	308.00
IUUC-Bdi-014712	Brachypodium distachyon	78.91	9.00e-69	251.00
IUUC-Bol-015583	Brassica oleracea	76.87	7.00e-69	252.00
IUUC-Bra-016748	Brassica rapa	76.87	2.00e-68	253.00
IUUC-Cel-018362	Caenorhabditis elegans	89.12	1.00e-78	284.00
IUUC-Cja-019302	Callithrix jacchus	100.00	9.00e-86	308.00
IUUC-Cfa-021087	Canis familiaris	100.00	9.00e-86	308.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	76.87	5.00e-68	249.00
IUUC-Csa-023668	Chlorocebus sabaeus	100.00	9.00e-86	308.00
IUUC-Cho-024987	Choloepus hoffmanni	100.00	9.00e-86	308.00
IUUC-Cin-025379	Ciona intestinalis	84.93	2.00e-74	270.00
IUUC-Csv-026311	Ciona savignyi	84.25	8.00e-73	265.00
IUUC-Cne-026957	Cryptococcus neoformans	77.40	2.00e-67	247.00
IUUC-Cme-027220	Cyanidioschyzon merolae	81.63	1.00e-71	261.00
IUUC-Dre-028568	Danio rerio	94.56	6.00e-81	292.00
IUUC-Dno-030067	Dasypus novemcinctus	100.00	9.00e-86	308.00
IUUC-Dor-030474	Dipodomys ordii	100.00	9.00e-86	308.00
IUUC-Ete-032540	Echinops telfairi	100.00	9.00e-86	308.00
IUUC-Eca-034167	Equus caballus	100.00	9.00e-86	308.00
IUUC-Gmo-038775	Gadus morhua	91.84	1.00e-78	284.00
IUUC-Gga-040873	Gallus gallus	100.00	9.00e-86	308.00
IUUC-Gma-043733	Glycine max	78.91	2.00e-69	253.00
IUUC-Ggo-045361	Gorilla gorilla	91.84	1.00e-79	287.00
IUUC-Hsa-045951	Homo sapiens	100.00	9.00e-86	308.00
IUUC-Hvu-047518	Hordeum vulgare	76.87	1.00e-58	218.00
IUUC-Itr-048743	Ictidomys tridecemlineatus	100.00	9.00e-86	308.00
IUUC-Kpa-049290	Komagataella pastoris	78.23	3.00e-68	249.00
IUUC-Lch-050109	Latimeria chalumnae	88.44	6.00e-77	278.00
IUUC-Lpe-051289	Leersia perrieri	77.55	2.00e-68	250.00
IUUC-Loc-051773	Lepisosteus oculatus	94.56	8.00e-81	291.00
IUUC-Laf-053673	Loxodonta africana	99.29	3.00e-81	293.00
IUUC-Mcc-055719	Macaca mulatta	100.00	9.00e-86	308.00
IUUC-Mtr-057667	Medicago truncatula	77.55	6.00e-68	249.00
IUUC-Mga-060138	Meleagris gallopavo	99.29	4.00e-81	292.00
IUUC-Mvi-060397	Microbotryum violaceum	80.27	4.00e-70	256.00
IUUC-Mmr-061212	Microcebus murinus	100.00	9.00e-86	308.00
IUUC-Mdo-062402	Monodelphis domestica	100.00	1.00e-81	294.00
IUUC-Mmu-063779	Mus musculus	100.00	9.00e-86	308.00
IUUC-Mac-064668	Musa acuminata	76.87	8.00e-69	253.00
IUUC-Mlu-067573	Myotis lucifugus	99.29	4.00e-81	292.00
IUUC-Ncr-068677	Neurospora crassa	78.23	1.00e-69	254.00
IUUC-Nle-069950	Nomascus leucogenys	100.00	9.00e-86	308.00
IUUC-Ont-072562	Oreochromis niloticus	90.48	1.00e-78	284.00
IUUC-Oan-073149	Ornithorhynchus anatinus	95.92	4.00e-82	296.00
IUUC-Oba-075411	Oryza barthii	77.55	3.00e-68	249.00
IUUC-Obr-076481	Oryza brachyantha	76.19	8.00e-68	248.00
IUUC-Ogl-076968	Oryza glaberrima	77.55	6.00e-69	252.00
IUUC-Ogu-078091	Oryza glumaepatula	76.55	8.00e-68	251.00
IUUC-Oin-079659	Oryza indica	77.55	6.00e-69	252.00
IUUC-Olo-080786	Oryza longistaminata	77.55	3.00e-68	249.00
IUUC-Ome-081967	Oryza meridionalis	76.19	8.00e-68	248.00
IUUC-Oni-082391	Oryza nivara	77.55	4.00e-69	254.00
IUUC-Opu-083481	Oryza punctata	76.87	7.00e-68	248.00
IUUC-Oru-085167	Oryza rufipogon	77.55	4.00e-69	254.00
IUUC-Osa-086003	Oryza sativa	77.55	6.00e-69	252.00
IUUC-Ola-087515	Oryzias latipes	91.16	5.00e-79	285.00
IUUC-Olu-087615	Ostreococcus lucimarinus	73.47	3.00e-63	233.00
IUUC-Oga-088915	Otolemur garnettii	100.00	9.00e-86	308.00
IUUC-Oar-090418	Ovis aries	97.95	3.00e-83	300.00
IUUC-Ptr-091575	Pan troglodytes	100.00	9.00e-86	308.00
IUUC-Pan-092922	Papio anubis	100.00	9.00e-86	308.00
IUUC-Ppa-095177	Physcomitrella patens	77.55	5.00e-69	252.00
IUUC-Pfo-096867	Poecilia formosa	91.16	5.00e-79	285.00
IUUC-Pab-098137	Pongo abelii	100.00	9.00e-86	308.00
IUUC-Pop-100017	Populus trichocarpa	77.55	7.00e-69	252.00
IUUC-Pca-100678	Procavia capensis	100.00	9.00e-86	308.00
IUUC-Ppe-101885	Prunus persica	77.55	7.00e-69	252.00
IUUC-Pva-102770	Pteropus vampyrus	100.00	9.00e-86	308.00
IUUC-Rno-106124	Rattus norvegicus	100.00	9.00e-86	308.00
IUUC-Sce-106153	Saccharomyces cerevisiae	80.56	9.00e-69	251.00
IUUC-Sha-106489	Sarcophilus harrisii	95.86	8.00e-82	295.00
IUUC-Smo-109317	Selaginella moellendorffii	77.55	1.00e-68	251.00
IUUC-Sit-109973	Setaria italica	77.55	2.00e-68	251.00
IUUC-Sly-111097	Solanum lycopersicum	78.23	4.00e-69	253.00
IUUC-Stu-112192	Solanum tuberosum	78.23	4.00e-69	253.00
IUUC-Sar-113557	Sorex araneus	100.00	7.00e-81	291.00
IUUC-Sbi-114840	Sorghum bicolor	77.55	5.00e-69	252.00
IUUC-Sre-115037	Sporisorium reilianum	75.69	5.00e-67	246.00
IUUC-Ssc-115391	Sus scrofa	91.84	1.00e-79	287.00
IUUC-Tgu-117399	Taeniopygia guttata	100.00	6.00e-84	302.00
IUUC-Tsy-118832	Tarsius syrichta	89.12	1.00e-76	277.00
IUUC-Tca-121413	Theobroma cacao	77.55	7.00e-69	252.00
IUUC-Tae-123340	Triticum aestivum	78.23	8.00e-70	255.00
IUUC-Tur-126518	Triticum urartu	76.19	1.00e-68	252.00
IUUC-Tme-126912	Tuber melanosporum	77.55	3.00e-69	253.00
IUUC-Ttr-128363	Tursiops truncatus	100.00	9.00e-86	308.00
IUUC-Vpa-130352	Vicugna pacos	92.81	1.00e-67	248.00
IUUC-Vvi-131700	Vitis vinifera	77.55	7.00e-69	252.00
IUUC-Xtr-132284	Xenopus tropicalis	95.24	9.00e-82	295.00
IUUC-Yli-134353	Yarrowia lipolytica	76.87	2.00e-69	253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence