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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Sce-106428
Ensembl Protein ID YHL009W-B
UniProt Accession P0C2J7; D3DKQ5; YH41B_YEAST
Genbank Protein ID DAA06678.1
Protein Name Transposon Ty4-H Gag-Pol polyprotein; TY4A-TY4B; Transposon Ty4 TYA-TYB polyprotein; Capsid protein; Ty4 protease; Integrase; Reverse transcriptase/ribonuclease H
Genbank Nucleotide ID U11581
Gene Name TY4B-H; YHLWTy4-1 POL; YHL009W-B; YHL008W-A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YHL009W-B YHL009W-B YHL009W-B
Annotation
mRNA Expression
GEO
Protein-protein Interaction
IIDiRefIndexMentha
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 25.23 1.20e-01 38.10 IUUC-Hsa-046980
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
 Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
Protein Sequence
(Fasta)
MATPVRDETR NVIDDNISAR IQSKVKTNDT VRQTPSSLRK VSIKDEQVKQ YQRNLNRFKT 60
ILNGLKAEEE KLSETDDIQM LAEKLLKLGE TIDKVENRIV DLVEKIQLLE TNENNNILHE 120
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Protein Fasta Sequence


>IUUC-Sce-106428|E3,F-box|Saccharomyces cerevisiae
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Nucleotide Sequence
(Fasta)
ATGGCGACCC CAGTGAGGGA TGAAACAAGA AATGTTATTG ACGACAACAT TTCTGCGCGG 60
ATTCAATCGA AAGTCAAAAC AAATGATACT GTCAGACAGA CGCCATCATC ATTAAGAAAA 120
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Nucleotide Fasta Sequence


>IUUC-Sce-106428|E3,F-box|Saccharomyces cerevisiae
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Sequence Source Ensembl
Keyword

KW-0064--Aspartyl protease
KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0229--DNA integration
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0239--DNA-directed DNA polymerase
KW-0255--Endonuclease
KW-0378--Hydrolase
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0511--Multifunctional enzyme
KW-0540--Nuclease
KW-0547--Nucleotide-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-0645--Protease
KW-1185--Reference proteome
KW-0688--Ribosomal frameshifting
KW-0694--RNA-binding
KW-0695--RNA-directed DNA polymerase
KW-0808--Transferase
KW-0814--Transposable element
KW-0815--Transposition
KW-0917--Virion maturation
KW-1188--Virus exit from host cell
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001584--Integrase_cat-core
IPR012337--RNaseH-like_dom
IPR013103--RVT_2
PROSITE

PS50994--INTEGRASE
Pfam

PF00665--rve
PF07727--RVT_2
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000943--C:retrotransposon nucleocapsid
GO:0004190--F:aspartic-type endopeptidase activity
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003887--F:DNA-directed DNA polymerase activity
GO:0046872--F:metal ion binding
GO:0008233--F:peptidase activity
GO:0004540--F:ribonuclease activity
GO:0003723--F:RNA binding
GO:0003964--F:RNA-directed DNA polymerase activity
GO:0004523--F:RNA-DNA hybrid ribonuclease activity
GO:0015074--P:DNA integration
GO:0006310--P:DNA recombination
GO:0032197--P:transposition, RNA-mediated
KEGG sce:YHL009W-B
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Bta-013435 Bos taurus 24.30 5.00e-04 36.20
IUUC-Cpo-022098 Cavia porcellus 24.30 3.00e-04 36.60
IUUC-Dre-028808 Danio rerio 32.56 3.30e-01 28.10
IUUC-Dno-029141 Dasypus novemcinctus 24.30 1.00e-03 34.30
IUUC-Eca-033564 Equus caballus 27.14 5.50e-01 28.10
IUUC-Fca-035783 Felis catus 25.23 2.00e-04 37.40
IUUC-Ggo-044871 Gorilla gorilla 25.23 1.00e-04 38.10
IUUC-Hsa-046980 Homo sapiens 25.23 1.00e-04 38.10
IUUC-Itr-048981 Ictidomys tridecemlineatus 25.23 1.00e-04 38.10
IUUC-Lch-050606 Latimeria chalumnae 50.00 2.20e-01 28.50
IUUC-Laf-054093 Loxodonta africana 23.36 3.00e-03 33.50
IUUC-Mdo-062841 Monodelphis domestica 24.30 1.00e-02 31.60
IUUC-Mmu-063279 Mus musculus 25.23 1.00e-04 37.70
IUUC-Mac-065668 Musa acuminata 26.61 1.90e-02 32.70
IUUC-Mpu-066829 Mustela putorius furo 25.23 5.00e-05 39.30
IUUC-Mlu-067889 Myotis lucifugus 25.23 5.00e-05 39.30
IUUC-Nle-069509 Nomascus leucogenys 41.67 2.30e-02 30.80
IUUC-Oan-073742 Ornithorhynchus anatinus 33.78 7.00e-03 32.00
IUUC-Oar-090113 Ovis aries 24.30 5.00e-04 36.20
IUUC-Ptr-090986 Pan troglodytes 24.30 1.00e-03 35.00
IUUC-Rno-105253 Rattus norvegicus 25.23 1.00e-04 37.70
IUUC-Stu-112857 Solanum tuberosum 22.77 1.50e+00 25.40
IUUC-Ssc-115419 Sus scrofa 24.30 6.00e-04 35.80
IUUC-Tur-126167 Triticum urartu 22.72 9.00e-13 68.90
IUUC-Tbe-127389 Tupaia belangeri 32.26 1.70e-01 29.30
IUUC-Vvi-131258 Vitis vinifera 28.37 1.00e-06 47.00
Created Date 25-Jun-2017

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