iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066554

Ensembl Protein ID

ENSMPUP00000008668.1

UniProt Accession

M3YBG1; M3YBG1_MUSPF

Genbank Protein ID

ENSMPUP00000008668

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01035241

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000008738.1	ENSMPUT00000008810.1	ENSMPUP00000008668.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.30e-68	230.4	417	795

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 417  GLINKGNWCYINATLQALVACPPMYHLMKF-IPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 503
           9***************************99.333333.334799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde............. 129
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+ +                  k+++++e e+e+      e             
   Q: 504  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLNlkkllspnneklpvsngPKSHSVNEDEQEEPG----Egsedeweqvgprn 588
           *9999999999966599********************4455577777667774444333333333333333....26666666666665 PP
   S: 130  ..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqe 216
             +  ++ +  +++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k k+++e
   Q: 589  ktSVTRQAEFVQTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDRIR---TVQDALESLVARESVQG----YTTKTKQEVE 669
           544444555555***********9.688999999*******************99...****************8....99999***** PP
   S: 217  aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYvayvkn 301
            +++++l+klP+vL+lhLkRf ++++++++ k+ k++++p  L++s+ + sp  k+k+   +++Y+L+avv+H+G s+ +GHY+++v +
   Q: 670  ISRRVTLEKLPPVLVLHLKRFVYEKTGGCQ-KLVKNIDYPVDLEISKELLSPGVKNKNfkcHRTYRLFAVVYHHGsSATGGHYTTDVFQ 757
           ***********************9998886.****************999988777777879*************************** PP
   S: 302  ekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
              + Wl++dD+ V+++++ +v++ t+ +taY+l+Y+r
   Q: 758  IGLNgWLRIDDQAVKVISQYQVVKPTAeRTAYLLYYRR 795
           87777*******************9889********98 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

TFFFLFQYIF GDFSPDEFNQ FFVTPRSSVE LPPYSGTVLC GPQDPDELPD GQEYQRIEFG 60
VNEVIEPSGA LPRAPSYSIS STLNPQAPEF ILSCTTSKKT PDDLDKEATY GAVDCQYPGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTTTTTT TCCTTTTCCA GTATATCTTC GGAGATTTCA GCCCTGATGA ATTCAATCAG 60
TTCTTCGTGA CTCCTCGCTC TTCGGTTGAG GTAAGACAAC GTTTTATTGA GTATGTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	30.56	2.00e-44	174.00
IUUC-Aml-001584	Ailuropoda melanoleuca	92.99	0.00e+00	1382.00
IUUC-Atr-002927	Amborella trichopoda	35.22	1.00e-58	221.00
IUUC-Apl-003988	Anas platyrhynchos	77.38	0.00e+00	1114.00
IUUC-Aca-004461	Anolis carolinensis	88.32	1.00e-163	568.00
IUUC-Aly-006038	Arabidopsis lyrata	35.90	8.00e-56	211.00
IUUC-Ath-007328	Arabidopsis thaliana	35.64	4.00e-54	205.00
IUUC-Ago-007717	Ashbya gossypii	31.01	2.00e-45	177.00
IUUC-Acl-008188	Aspergillus clavatus	35.29	6.00e-63	235.00
IUUC-Afl-008456	Aspergillus flavus	37.09	2.00e-48	186.00
IUUC-Afu-009067	Aspergillus fumigatus	36.02	2.00e-66	247.00
IUUC-Ani-009483	Aspergillus nidulans	33.48	3.00e-62	233.00
IUUC-Ang-009639	Aspergillus niger	34.36	2.00e-60	227.00
IUUC-Aor-010040	Aspergillus oryzae	34.78	4.00e-60	226.00
IUUC-Ate-010310	Aspergillus terreus	34.51	5.00e-62	232.00
IUUC-Ame-011012	Astyanax mexicanus	78.05	4.00e-163	568.00
IUUC-Bgr-012311	Blumeria graminis	34.86	5.00e-45	176.00
IUUC-Bta-013299	Bos taurus	88.30	0.00e+00	1269.00
IUUC-Bci-013783	Botrytis cinerea	36.25	2.00e-57	217.00
IUUC-Bdi-015039	Brachypodium distachyon	32.03	4.00e-49	189.00
IUUC-Bol-015806	Brassica oleracea	37.44	1.00e-63	237.00
IUUC-Bra-017076	Brassica rapa	37.44	1.00e-63	237.00
IUUC-Cja-018715	Callithrix jacchus	86.38	0.00e+00	1278.00
IUUC-Cfa-020194	Canis familiaris	93.86	0.00e+00	1398.00
IUUC-Cpo-022272	Cavia porcellus	74.03	0.00e+00	1007.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.12	1.00e-34	141.00
IUUC-Csa-023310	Chlorocebus sabaeus	87.77	0.00e+00	1298.00
IUUC-Cho-024966	Choloepus hoffmanni	75.75	0.00e+00	882.00
IUUC-Cin-025616	Ciona intestinalis	47.61	3.00e-105	375.00
IUUC-Csv-026043	Ciona savignyi	45.77	3.00e-99	355.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	34.95	2.00e-46	181.00
IUUC-Cne-026962	Cryptococcus neoformans	35.71	2.00e-51	197.00
IUUC-Cme-027113	Cyanidioschyzon merolae	31.38	1.00e-39	157.00
IUUC-Dre-028072	Danio rerio	77.63	0.00e+00	709.00
IUUC-Dno-029489	Dasypus novemcinctus	86.57	0.00e+00	1304.00
IUUC-Dor-031068	Dipodomys ordii	72.75	3.00e-133	469.00
IUUC-Dse-031553	Dothistroma septosporum	36.69	2.00e-56	214.00
IUUC-Dme-031759	Drosophila melanogaster	42.79	4.00e-85	310.00
IUUC-Ete-032549	Echinops telfairi	77.97	0.00e+00	837.00
IUUC-Eca-033380	Equus caballus	88.16	0.00e+00	1330.00
IUUC-Eeu-034818	Erinaceus europaeus	83.63	0.00e+00	1223.00
IUUC-Fca-035535	Felis catus	90.82	0.00e+00	1269.00
IUUC-Fal-036627	Ficedula albicollis	75.72	0.00e+00	1068.00
IUUC-Fox-037904	Fusarium oxysporum	36.87	6.00e-55	209.00
IUUC-Fso-038170	Fusarium solani	33.05	8.00e-53	202.00
IUUC-Gmo-039499	Gadus morhua	72.02	0.00e+00	650.00
IUUC-Ggr-040042	Gaeumannomyces graminis	36.34	1.00e-61	231.00
IUUC-Gga-040571	Gallus gallus	77.99	0.00e+00	1115.00
IUUC-Gac-041345	Gasterosteus aculeatus	78.77	0.00e+00	658.00
IUUC-Gma-043436	Glycine max	35.13	3.00e-59	223.00
IUUC-Ggo-044652	Gorilla gorilla	87.77	0.00e+00	1316.00
IUUC-Hsa-045864	Homo sapiens	88.02	0.00e+00	1322.00
IUUC-Hvu-047071	Hordeum vulgare	33.25	6.00e-53	201.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	90.24	0.00e+00	978.00
IUUC-Kpa-049132	Komagataella pastoris	31.17	3.00e-47	182.00
IUUC-Lch-050040	Latimeria chalumnae	69.26	0.00e+00	902.00
IUUC-Loc-052449	Lepisosteus oculatus	78.42	0.00e+00	689.00
IUUC-Lma-053248	Leptosphaeria maculans	36.97	7.00e-60	225.00
IUUC-Laf-054121	Loxodonta africana	85.57	0.00e+00	1276.00
IUUC-Mcc-055514	Macaca mulatta	87.89	0.00e+00	1304.00
IUUC-Meu-056873	Macropus eugenii	71.16	0.00e+00	793.00
IUUC-Mor-057243	Magnaporthe oryzae	33.67	7.00e-58	219.00
IUUC-Mpo-057439	Magnaporthe poae	35.88	8.00e-61	228.00
IUUC-Mtr-058457	Medicago truncatula	34.62	1.00e-57	217.00
IUUC-Mla-058929	Melampsora laricipopulina	31.03	1.00e-55	211.00
IUUC-Mga-060157	Meleagris gallopavo	76.14	0.00e+00	1117.00
IUUC-Mvi-060442	Microbotryum violaceum	34.87	2.00e-53	204.00
IUUC-Mmr-061062	Microcebus murinus	87.25	0.00e+00	1316.00
IUUC-Mdo-062798	Monodelphis domestica	79.92	0.00e+00	1162.00
IUUC-Mmu-064050	Mus musculus	81.11	0.00e+00	1202.00
IUUC-Mac-065619	Musa acuminata	33.76	1.00e-53	203.00
IUUC-Mlu-068003	Myotis lucifugus	87.28	0.00e+00	1309.00
IUUC-Nfi-068612	Neosartorya fischeri	34.74	8.00e-65	241.00
IUUC-Ncr-068878	Neurospora crassa	35.40	3.00e-52	200.00
IUUC-Nle-069661	Nomascus leucogenys	88.27	0.00e+00	1306.00
IUUC-Opr-070944	Ochotona princeps	78.69	9.00e-160	556.00
IUUC-Ont-071266	Oreochromis niloticus	79.15	0.00e+00	679.00
IUUC-Oan-073442	Ornithorhynchus anatinus	78.56	0.00e+00	1104.00
IUUC-Ocu-073788	Oryctolagus cuniculus	79.52	0.00e+00	1075.00
IUUC-Oba-075085	Oryza barthii	34.53	4.00e-38	151.00
IUUC-Obr-076663	Oryza brachyantha	33.42	5.00e-46	179.00
IUUC-Ogl-076937	Oryza glaberrima	30.81	9.00e-49	187.00
IUUC-Ogu-078909	Oryza glumaepatula	31.01	6.00e-47	182.00
IUUC-Oin-079617	Oryza indica	32.23	4.00e-48	186.00
IUUC-Olo-081043	Oryza longistaminata	26.56	4.00e-25	109.00
IUUC-Ome-081646	Oryza meridionalis	25.52	6.00e-24	105.00
IUUC-Oni-082914	Oryza nivara	31.01	5.00e-47	182.00
IUUC-Oru-084878	Oryza rufipogon	31.01	5.00e-47	182.00
IUUC-Osa-085822	Oryza sativa	31.70	7.00e-51	194.00
IUUC-Ola-086931	Oryzias latipes	58.31	0.00e+00	765.00
IUUC-Oga-088443	Otolemur garnettii	86.93	0.00e+00	1326.00
IUUC-Oar-089325	Ovis aries	84.44	0.00e+00	1183.00
IUUC-Ptr-091584	Pan troglodytes	84.99	0.00e+00	1228.00
IUUC-Pan-092551	Papio anubis	86.00	0.00e+00	1266.00
IUUC-Psi-093366	Pelodiscus sinensis	73.06	0.00e+00	653.00
IUUC-Pno-095136	Phaeosphaeria nodorum	34.58	1.00e-52	201.00
IUUC-Ppa-095574	Physcomitrella patens	35.83	5.00e-60	225.00
IUUC-Pfo-097462	Poecilia formosa	77.25	0.00e+00	681.00
IUUC-Pab-098547	Pongo abelii	88.15	0.00e+00	1300.00
IUUC-Pop-099529	Populus trichocarpa	37.44	1.00e-62	234.00
IUUC-Pca-101066	Procavia capensis	77.30	0.00e+00	1113.00
IUUC-Ppe-102110	Prunus persica	37.06	3.00e-60	225.00
IUUC-Pva-103015	Pteropus vampyrus	84.26	0.00e+00	1236.00
IUUC-Ptt-103998	Puccinia triticina	32.59	4.00e-52	199.00
IUUC-Pte-104417	Pyrenophora teres	33.92	2.00e-54	207.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	35.11	3.00e-54	207.00
IUUC-Rno-105533	Rattus norvegicus	81.89	0.00e+00	1209.00
IUUC-Sce-106160	Saccharomyces cerevisiae	28.69	6.00e-39	156.00
IUUC-Sha-106590	Sarcophilus harrisii	79.45	0.00e+00	1154.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	35.20	5.00e-57	215.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.56	4.00e-65	242.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	36.22	4.00e-59	223.00
IUUC-Smo-108842	Selaginella moellendorffii	36.92	4.00e-39	154.00
IUUC-Sit-110781	Setaria italica	31.97	4.00e-55	209.00
IUUC-Sly-111797	Solanum lycopersicum	33.50	2.00e-54	206.00
IUUC-Stu-112188	Solanum tuberosum	35.28	5.00e-56	212.00
IUUC-Sbi-114862	Sorghum bicolor	32.78	4.00e-44	172.00
IUUC-Sre-115162	Sporisorium reilianum	34.80	2.00e-66	247.00
IUUC-Ssc-115505	Sus scrofa	95.47	5.00e-164	570.00
IUUC-Tgu-116535	Taeniopygia guttata	75.94	0.00e+00	1075.00
IUUC-Tru-117542	Takifugu rubripes	77.85	0.00e+00	711.00
IUUC-Tni-120200	Tetraodon nigroviridis	58.67	0.00e+00	799.00
IUUC-Tca-121548	Theobroma cacao	35.24	2.00e-44	173.00
IUUC-Tre-122124	Trichoderma reesei	36.41	3.00e-61	229.00
IUUC-Tvi-122457	Trichoderma virens	35.39	6.00e-55	209.00
IUUC-Tae-125646	Triticum aestivum	33.92	1.00e-54	208.00
IUUC-Tme-127180	Tuber melanosporum	39.89	3.00e-70	259.00
IUUC-Tbe-127530	Tupaia belangeri	74.87	0.00e+00	1019.00
IUUC-Ttr-128549	Tursiops truncatus	80.10	0.00e+00	1179.00
IUUC-Uma-129381	Ustilago maydis	33.40	1.00e-65	244.00
IUUC-Vda-129889	Verticillium dahliae	32.37	3.00e-51	197.00
IUUC-Vpa-130100	Vicugna pacos	83.65	0.00e+00	1208.00
IUUC-Vvi-131366	Vitis vinifera	36.90	8.00e-65	241.00
IUUC-Xtr-132048	Xenopus tropicalis	61.51	0.00e+00	883.00
IUUC-Xma-133593	Xiphophorus maculatus	78.16	0.00e+00	678.00
IUUC-Yli-134338	Yarrowia lipolytica	30.92	6.00e-33	135.00
IUUC-Zma-135586	Zea mays	32.13	5.00e-48	185.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence