iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090349

Ensembl Protein ID

ENSOARP00000003616.1

UniProt Accession

W5NZL8; W5NZL8_SHEEP

Genbank Protein ID

ENSOARP00000003616

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01052775

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000003388.1	ENSOART00000003681.1	ENSOARP00000003616.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.30e-18	64.7	34	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.10e-10	39.7	132	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+ g++  ++h+++L+a+S++F+  fl+e +e k k++v+++ v+p v+  ++k+lY+ ++d+n+
   Q: 34   DCTLKAGDKSLPCHRLILSACSPYFREYFLSEIDEAK-KKEVVLDNVDPAVLDLIIKYLYSATIDLND 100
           9***********************************9.***************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Ncl+ilr++ l+dcp+L+ +a++f+++ F
   Q: 132  PGNCLAILRLGLLLDCPRLAISAREFVSDRF 162
           56***************************99 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MDSQRELAEE LRLYQSTLLQ DGLKDLLDEK KFIDCTLKAG DKSLPCHRLI LSACSPYFRE 60
YFLSEIDEAK KKEVVLDNVD PAVLDLIIKY LYSATIDLND GNVQDIFALA SRFQIPSVFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTCCC AGCGGGAACT CGCAGAGGAA CTGCGGCTTT ACCAATCCAC CCTTCTTCAG 60
GATGGTCTAA AAGATCTCCT GGATGAGAAA AAATTCATCG ATTGCACCCT AAAAGCAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

KEGG

oas:101120303

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	97.03	0.00e+00	1182.00
IUUC-Apl-003866	Anas platyrhynchos	85.48	0.00e+00	1035.00
IUUC-Aca-005275	Anolis carolinensis	51.20	9.00e-180	623.00
IUUC-Ame-011172	Astyanax mexicanus	61.86	0.00e+00	753.00
IUUC-Bta-012925	Bos taurus	99.17	0.00e+00	1201.00
IUUC-Bci-013875	Botrytis cinerea	29.58	1.00e-19	90.50
IUUC-Bdi-014115	Brachypodium distachyon	24.05	9.00e-12	64.70
IUUC-Cja-019348	Callithrix jacchus	96.70	0.00e+00	1182.00
IUUC-Cfa-020782	Canis familiaris	98.02	0.00e+00	1190.00
IUUC-Cpo-021825	Cavia porcellus	92.90	0.00e+00	1134.00
IUUC-Csa-023184	Chlorocebus sabaeus	96.55	0.00e+00	1011.00
IUUC-Cin-025237	Ciona intestinalis	29.62	1.00e-70	260.00
IUUC-Dre-028278	Danio rerio	60.43	0.00e+00	775.00
IUUC-Dno-029516	Dasypus novemcinctus	94.88	0.00e+00	1162.00
IUUC-Dor-030850	Dipodomys ordii	92.21	0.00e+00	754.00
IUUC-Ete-032697	Echinops telfairi	93.40	0.00e+00	1125.00
IUUC-Eca-033714	Equus caballus	98.18	0.00e+00	1191.00
IUUC-Eeu-035245	Erinaceus europaeus	94.02	0.00e+00	1064.00
IUUC-Gmo-039392	Gadus morhua	57.80	0.00e+00	733.00
IUUC-Ggr-040041	Gaeumannomyces graminis	28.47	7.00e-09	54.70
IUUC-Gga-041106	Gallus gallus	85.15	0.00e+00	1051.00
IUUC-Gac-042252	Gasterosteus aculeatus	61.19	0.00e+00	774.00
IUUC-Ggo-044817	Gorilla gorilla	97.19	0.00e+00	1186.00
IUUC-Hsa-046620	Homo sapiens	97.36	0.00e+00	1187.00
IUUC-Lch-050477	Latimeria chalumnae	69.80	0.00e+00	859.00
IUUC-Loc-051955	Lepisosteus oculatus	72.44	0.00e+00	915.00
IUUC-Laf-053500	Loxodonta africana	95.87	0.00e+00	1168.00
IUUC-Mcc-055316	Macaca mulatta	96.86	0.00e+00	1182.00
IUUC-Mga-059451	Meleagris gallopavo	57.19	0.00e+00	708.00
IUUC-Mmr-061444	Microcebus murinus	97.03	0.00e+00	1182.00
IUUC-Mmu-064147	Mus musculus	95.21	0.00e+00	1165.00
IUUC-Mlu-067481	Myotis lucifugus	94.88	0.00e+00	1159.00
IUUC-Ncr-068938	Neurospora crassa	30.10	4.00e-08	52.80
IUUC-Nle-069339	Nomascus leucogenys	97.19	0.00e+00	1187.00
IUUC-Opr-070703	Ochotona princeps	95.71	0.00e+00	1125.00
IUUC-Ont-072420	Oreochromis niloticus	60.13	0.00e+00	792.00
IUUC-Oan-073476	Ornithorhynchus anatinus	92.74	0.00e+00	1135.00
IUUC-Ocu-074248	Oryctolagus cuniculus	96.53	0.00e+00	1182.00
IUUC-Ola-086361	Oryzias latipes	61.50	0.00e+00	778.00
IUUC-Pan-092069	Papio anubis	97.03	0.00e+00	1183.00
IUUC-Psi-093671	Pelodiscus sinensis	87.46	0.00e+00	1047.00
IUUC-Pma-094586	Petromyzon marinus	57.65	9.00e-93	333.00
IUUC-Pfo-096122	Poecilia formosa	62.46	0.00e+00	810.00
IUUC-Pab-098711	Pongo abelii	97.19	0.00e+00	1187.00
IUUC-Pca-100495	Procavia capensis	87.79	0.00e+00	1048.00
IUUC-Pva-102401	Pteropus vampyrus	97.36	0.00e+00	1186.00
IUUC-Rno-105969	Rattus norvegicus	94.88	0.00e+00	1160.00
IUUC-Sar-113405	Sorex araneus	92.41	0.00e+00	1117.00
IUUC-Tgu-116725	Taeniopygia guttata	85.31	0.00e+00	1070.00
IUUC-Tru-117743	Takifugu rubripes	59.37	0.00e+00	765.00
IUUC-Tsy-119225	Tarsius syrichta	89.60	0.00e+00	1076.00
IUUC-Tni-120547	Tetraodon nigroviridis	62.29	0.00e+00	792.00
IUUC-Ttr-128645	Tursiops truncatus	97.85	0.00e+00	1189.00
IUUC-Vpa-130714	Vicugna pacos	97.52	0.00e+00	1187.00
IUUC-Xtr-132144	Xenopus tropicalis	76.07	0.00e+00	939.00
IUUC-Xma-133860	Xiphophorus maculatus	62.62	0.00e+00	811.00
IUUC-Yli-134535	Yarrowia lipolytica	23.03	1.00e-06	47.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence