iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000009886.5	ENSGALT00000080730.1	ENSGALP00000048919.1
ENSGALG00000009886.5	ENSGALT00000016070.5	ENSGALP00000016052.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.80e-81	272.2	446	943

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNS++Q+L++ +++r+ +l+ + + +n         +l+++lq+lf+ l +++++a++pr +l+a +   + f+  +q
   Q: 446  TGLINLGNTCYMNSIIQALFMATDFRRHVLSLNLNGCN---------SLMRKLQHLFAFLAHTQREAYAPRIFLEASR--PPWFTPQSQ 523
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+fll++l+ee       ++ +  e++++++s++++         +   k +++++li+++F+g+lk++i cl+c+++s++ee
   Q: 524  QDCSEYLRFLLNRLHEEERTlkaLSSAKAAESRKNEESQAQETvhkaqvfaEALCKGSEERTLIERMFGGKLKTTICCLNCKSTSQKEE 612
           *****************95555522333333333333333333666677766677788888**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++   ++ +                                                                         
   Q: 613  AFTDLSLAFCPPTSLESAgvkclehseikdgsvvqssisatpagetppssleinggcnaitnegilkdsaepnsepksefnkdqdsrdv 701
           *********999976555999******************************************************************** PP
   S: 186  ..........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
                     s++d+L+ f ++e l g+nkyycekc ++q+aek++++ + Pe+Lil L Rfs++ + + r+ki ++v++pl L+l   
   Q: 702  ssalvgkntpSVTDLLNYFLAPEILSGDNKYYCEKCASLQNAEKTMQIIEEPEYLILTLLRFSYDPKCHIRRKILDSVSLPLLLELPVR 790
           *********************************************************************************99999853 PP
   S: 265  cts................................peekqke.....kkkYeLiavvvHsG.slssGHYvayvkn.............. 301
            ++                                +     e      + Y L++vvvHsG s++sGHY++y++n              
   Q: 791  RATsplavvsgswsvdveisdigenlakklkpsgaD-----EvscpqLVPYVLSSVVVHSGvSSESGHYYSYARNvtgsgssgqchqsk 874
           333467777777777777777776666666655553.....0455559***************************************** PP
   S: 302  ............................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                         ++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 875  afslistqnkllaeegpctvieneldteMPKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLIYKKQ 943
           *****999999999999999877665543455*******************999************986 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MDKILEGLVS SSHPLPLKRV IVRRVVELAE TPLSQAQCRA MFALGTRLVL QGPDAFQRQV 60
GRQVLEAYGR YHRAEFEAFF NRGLVLGLLQ RGYGELSCRD PAILDYIQAG LRLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGG GCTGGTGAGC TCGTCCCACC CGCTGCCGCT GAAGCGCGTC 60
ATCGTGCGGC GGGTGGTGGA GCTGGCCGAG ACGCCGCTGA GCCAGGCGCA GTGCCGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	72.82	0.00e+00	1416.00
IUUC-Apl-003435	Anas platyrhynchos	91.83	0.00e+00	1597.00
IUUC-Aca-004556	Anolis carolinensis	75.69	0.00e+00	1383.00
IUUC-Ame-010616	Astyanax mexicanus	61.00	0.00e+00	1179.00
IUUC-Bta-013544	Bos taurus	73.76	0.00e+00	1437.00
IUUC-Cja-018745	Callithrix jacchus	72.49	0.00e+00	1415.00
IUUC-Cfa-020434	Canis familiaris	73.50	0.00e+00	1436.00
IUUC-Cpo-021666	Cavia porcellus	74.19	0.00e+00	1394.00
IUUC-Csa-023965	Chlorocebus sabaeus	74.21	0.00e+00	1482.00
IUUC-Cho-024809	Choloepus hoffmanni	67.52	0.00e+00	969.00
IUUC-Csv-026333	Ciona savignyi	43.75	1.00e-32	132.00
IUUC-Dre-028338	Danio rerio	60.36	0.00e+00	1169.00
IUUC-Dno-029372	Dasypus novemcinctus	73.85	0.00e+00	1452.00
IUUC-Dor-030752	Dipodomys ordii	73.80	0.00e+00	997.00
IUUC-Ete-032588	Echinops telfairi	65.89	0.00e+00	901.00
IUUC-Eca-034416	Equus caballus	73.88	0.00e+00	1461.00
IUUC-Eeu-035132	Erinaceus europaeus	59.50	0.00e+00	1087.00
IUUC-Fca-036137	Felis catus	73.59	0.00e+00	1458.00
IUUC-Fal-037297	Ficedula albicollis	89.70	0.00e+00	1780.00
IUUC-Gmo-038727	Gadus morhua	62.23	0.00e+00	969.00
IUUC-Gac-042082	Gasterosteus aculeatus	60.13	0.00e+00	1082.00
IUUC-Ggo-045376	Gorilla gorilla	69.93	0.00e+00	1328.00
IUUC-Hsa-046444	Homo sapiens	74.21	0.00e+00	1459.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	74.05	0.00e+00	1465.00
IUUC-Lch-050500	Latimeria chalumnae	67.28	0.00e+00	1306.00
IUUC-Loc-052625	Lepisosteus oculatus	63.82	0.00e+00	1251.00
IUUC-Laf-053689	Loxodonta africana	73.05	0.00e+00	1434.00
IUUC-Mcc-055286	Macaca mulatta	74.02	0.00e+00	1446.00
IUUC-Mga-059905	Meleagris gallopavo	96.57	0.00e+00	1668.00
IUUC-Mmr-061397	Microcebus murinus	74.50	0.00e+00	1452.00
IUUC-Mdo-062833	Monodelphis domestica	74.88	0.00e+00	1512.00
IUUC-Mmu-063157	Mus musculus	72.71	0.00e+00	1423.00
IUUC-Mpu-066434	Mustela putorius furo	74.02	0.00e+00	1458.00
IUUC-Mlu-068178	Myotis lucifugus	72.98	0.00e+00	1400.00
IUUC-Nle-070153	Nomascus leucogenys	73.35	0.00e+00	1404.00
IUUC-Ont-072330	Oreochromis niloticus	60.52	0.00e+00	1169.00
IUUC-Oan-072709	Ornithorhynchus anatinus	76.07	0.00e+00	1196.00
IUUC-Ocu-074832	Oryctolagus cuniculus	73.73	0.00e+00	1446.00
IUUC-Ola-087003	Oryzias latipes	55.96	2.00e-44	171.00
IUUC-Oga-088517	Otolemur garnettii	71.33	0.00e+00	1390.00
IUUC-Oar-089472	Ovis aries	71.52	0.00e+00	1369.00
IUUC-Ptr-090996	Pan troglodytes	73.93	0.00e+00	1452.00
IUUC-Pan-091837	Papio anubis	72.28	0.00e+00	1421.00
IUUC-Psi-093236	Pelodiscus sinensis	81.73	0.00e+00	1263.00
IUUC-Pma-094349	Petromyzon marinus	53.57	0.00e+00	940.00
IUUC-Pfo-097193	Poecilia formosa	60.30	0.00e+00	1103.00
IUUC-Pab-098710	Pongo abelii	73.52	0.00e+00	1454.00
IUUC-Pca-100794	Procavia capensis	64.41	0.00e+00	1219.00
IUUC-Pva-102722	Pteropus vampyrus	72.74	0.00e+00	1421.00
IUUC-Rno-105743	Rattus norvegicus	72.52	0.00e+00	1397.00
IUUC-Sha-106563	Sarcophilus harrisii	75.89	0.00e+00	1249.00
IUUC-Sar-113533	Sorex araneus	66.63	0.00e+00	1251.00
IUUC-Ssc-116259	Sus scrofa	81.87	0.00e+00	845.00
IUUC-Tgu-117475	Taeniopygia guttata	88.42	0.00e+00	1586.00
IUUC-Tru-118623	Takifugu rubripes	60.04	0.00e+00	1088.00
IUUC-Tsy-119250	Tarsius syrichta	75.00	0.00e+00	1151.00
IUUC-Tni-120441	Tetraodon nigroviridis	57.05	0.00e+00	1030.00
IUUC-Tbe-127936	Tupaia belangeri	63.51	0.00e+00	1152.00
IUUC-Ttr-128483	Tursiops truncatus	63.10	0.00e+00	1059.00
IUUC-Vpa-130303	Vicugna pacos	83.55	0.00e+00	915.00
IUUC-Xtr-132773	Xenopus tropicalis	67.14	0.00e+00	1289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence