iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059905

UUCD1 version

UUC-MeG-00853

Ensembl Protein ID

ENSMGAP00000003179.1

UniProt Accession

G1MWM9; G1MWM9_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000003451.1	ENSMGAT00000003876.1	ENSMGAP00000003179.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.80e-81	271.8	328	826

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNS++Q+L++ +++r+ +l+ + + +n         +l+++lq+lf+ l +++++a++pr +l+a +   + f+  +q
   Q: 328  TGLINLGNTCYMNSIIQALYMATDFRRHVLSLNLNGCN---------SLMRKLQHLFAFLAHTQREAYAPRIFLEASR--PPWFTPQSQ 405
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk.......eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvs 163
           qD++E+l+fll++l+ee k        +      e++ +++s++++         +   k +++++li+++F+g+lk++i cl+c+++s
   Q: 406  QDCSEYLRFLLNRLHEEEKTlkalssaK----AAESRRNEESQAQETihkaqvfaEALCKGSEERTLIERMFGGKLKTTICCLNCKSTS 490
           ******************7766543320....222223332333333566677766677788888************************ PP
   S: 164  sreepfldlslpvpgkeetkke................................................................... 185
           ++ee f+dlsl++   ++ +                                                                     
   Q: 491  QKEEAFTDLSLAFCPPTSLESAsvkcvehaemkdssvvqttisassagetplsrleinsgcnaltnegilkdfsaepnsetksefnkdq 579
           *************988866555899**************************************************************** PP
   S: 186  ...............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
                          s++d+L+ f ++e l g+nkyycekc ++q+aek++++ + Pe+Lil L Rfs++ + ++r+ki ++v++pl L
   Q: 580  dnrdvssalvgkstpSVTDLLNYFLAPEILSGDNKYYCEKCASLQNAEKTMQIVEEPEYLILTLLRFSYDPKCHVRRKILDSVSLPLLL 668
           **************************************************************************************999 PP
   S: 260  dlspfcts................................peekqke.....kkkYeLiavvvHsG.slssGHYvayvkn......... 301
           +l    ++                                +     e      + Y L++vvvHsG s++sGHY++y++n         
   Q: 669  ELPVKRATsplavvsgswsvdveisdigenlakklkpsgaD-----EvscpqLVPYVLSSVVVHSGvSSESGHYYSYARNvtgsgssgq 752
           99853333367777777777777777776666666655553.....0455559************************************ PP
   S: 302  .................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                              ++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 753  chqskafslispqnkllaeespctvieneldteMPKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLIYKKQ 826
           **********999999999999999887665543455*******************999************986 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

XVLELFELLQ VEALRLVCER PAPPLCARLC QLLGDFPQCL PRGRKLSLAF CQQLVRSIAH 60
FQSRGSREAE LRLYVSQVTQ VSGLLRSVWK AEPDTLLPSL QELFAVIAAA DTPFEPSVAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NCGGTGCTGG AGCTCTTCGA GCTGCTGCAG GTGGAGGCCC TGCGCCTGGT GTGTGAGCGG 60
CCCGCGCCGC CGCTCTGCGC TCGCCTGTGC CAGCTGCTGG GCGACTTCCC GCAGTGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	73.09	0.00e+00	1234.00
IUUC-Apl-003435	Anas platyrhynchos	90.96	0.00e+00	1570.00
IUUC-Aca-004556	Anolis carolinensis	76.03	0.00e+00	1258.00
IUUC-Ame-010616	Astyanax mexicanus	60.25	0.00e+00	1028.00
IUUC-Bta-013544	Bos taurus	74.13	0.00e+00	1259.00
IUUC-Cja-018745	Callithrix jacchus	72.87	0.00e+00	1239.00
IUUC-Cfa-020434	Canis familiaris	74.16	0.00e+00	1263.00
IUUC-Cpo-021666	Cavia porcellus	73.84	0.00e+00	1209.00
IUUC-Csa-023965	Chlorocebus sabaeus	74.59	0.00e+00	1305.00
IUUC-Cho-024809	Choloepus hoffmanni	67.72	0.00e+00	966.00
IUUC-Csv-026333	Ciona savignyi	43.43	4.00e-32	130.00
IUUC-Dre-028338	Danio rerio	60.49	0.00e+00	1009.00
IUUC-Dno-029372	Dasypus novemcinctus	74.05	0.00e+00	1270.00
IUUC-Dor-030752	Dipodomys ordii	73.67	0.00e+00	991.00
IUUC-Dme-031871	Drosophila melanogaster	28.11	9.00e-47	181.00
IUUC-Ete-032588	Echinops telfairi	66.41	0.00e+00	905.00
IUUC-Eca-034416	Equus caballus	74.62	0.00e+00	1290.00
IUUC-Eeu-035132	Erinaceus europaeus	58.43	0.00e+00	937.00
IUUC-Fca-036137	Felis catus	74.08	0.00e+00	1277.00
IUUC-Fal-037297	Ficedula albicollis	88.48	0.00e+00	1554.00
IUUC-Gmo-038727	Gadus morhua	63.20	0.00e+00	831.00
IUUC-Gga-041091	Gallus gallus	96.62	0.00e+00	1659.00
IUUC-Gac-042082	Gasterosteus aculeatus	59.64	0.00e+00	961.00
IUUC-Ggo-045376	Gorilla gorilla	69.86	0.00e+00	1153.00
IUUC-Hsa-046444	Homo sapiens	74.49	0.00e+00	1281.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	74.38	0.00e+00	1283.00
IUUC-Lch-050500	Latimeria chalumnae	66.89	0.00e+00	1170.00
IUUC-Loc-052625	Lepisosteus oculatus	63.32	0.00e+00	1090.00
IUUC-Laf-053689	Loxodonta africana	74.03	0.00e+00	1276.00
IUUC-Mcc-055286	Macaca mulatta	74.38	0.00e+00	1269.00
IUUC-Mmr-061397	Microcebus murinus	74.81	0.00e+00	1277.00
IUUC-Mdo-062833	Monodelphis domestica	75.91	0.00e+00	1341.00
IUUC-Mmu-063157	Mus musculus	72.97	0.00e+00	1247.00
IUUC-Mpu-066434	Mustela putorius furo	74.49	0.00e+00	1282.00
IUUC-Mlu-068178	Myotis lucifugus	73.43	0.00e+00	1227.00
IUUC-Nle-070153	Nomascus leucogenys	73.51	0.00e+00	1229.00
IUUC-Ont-072330	Oreochromis niloticus	60.56	0.00e+00	1036.00
IUUC-Oan-072709	Ornithorhynchus anatinus	76.32	0.00e+00	1201.00
IUUC-Ocu-074832	Oryctolagus cuniculus	74.09	0.00e+00	1273.00
IUUC-Ola-087003	Oryzias latipes	56.48	1.00e-44	172.00
IUUC-Oga-088517	Otolemur garnettii	71.34	0.00e+00	1219.00
IUUC-Oar-089472	Ovis aries	71.75	0.00e+00	1197.00
IUUC-Ptr-090996	Pan troglodytes	74.16	0.00e+00	1276.00
IUUC-Pan-091837	Papio anubis	72.64	0.00e+00	1245.00
IUUC-Psi-093236	Pelodiscus sinensis	80.95	0.00e+00	1256.00
IUUC-Pfo-097193	Poecilia formosa	59.79	0.00e+00	962.00
IUUC-Pab-098710	Pongo abelii	73.70	0.00e+00	1276.00
IUUC-Pca-100794	Procavia capensis	64.33	0.00e+00	1048.00
IUUC-Pva-102722	Pteropus vampyrus	73.25	0.00e+00	1242.00
IUUC-Rno-105743	Rattus norvegicus	72.65	0.00e+00	1227.00
IUUC-Sha-106563	Sarcophilus harrisii	76.04	0.00e+00	1253.00
IUUC-Sar-113533	Sorex araneus	64.73	0.00e+00	1059.00
IUUC-Ssc-116259	Sus scrofa	83.81	0.00e+00	662.00
IUUC-Tgu-117475	Taeniopygia guttata	88.15	0.00e+00	1552.00
IUUC-Tru-118623	Takifugu rubripes	59.74	0.00e+00	947.00
IUUC-Tsy-119250	Tarsius syrichta	75.58	0.00e+00	1155.00
IUUC-Tni-120441	Tetraodon nigroviridis	56.44	0.00e+00	872.00
IUUC-Tbe-127936	Tupaia belangeri	62.34	0.00e+00	971.00
IUUC-Ttr-128483	Tursiops truncatus	62.77	0.00e+00	1027.00
IUUC-Vpa-130303	Vicugna pacos	86.06	0.00e+00	745.00
IUUC-Xtr-132773	Xenopus tropicalis	67.02	0.00e+00	1142.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence