iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012630

Ensembl Protein ID

ENSBTAP00000003560.4

UniProt Accession

Q8MJ50; OSTF1_BOVIN

Genbank Protein ID

AAM82160.1; AAI12670.1

Protein Name

Osteoclast-stimulating factor 1

Genbank Nucleotide ID

AF523267; BC112669

Gene Name

OSTF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000002746.4	ENSBTAT00000003560.4	ENSBTAP00000003560.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.70e-15	54.6	14	68

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            +++++ly +e+ + deL +++Gd++++   +  d +W+kg  + +g+ Gl+P+n+v++
   Q: 14   VKVFRALYTFEPRTPDELYFEEGDIIYIT--DMSDTNWWKG--TCKGRTGLIPSNYVAE 68
           57899***********************7..99********..8*************86 PP

Organism

Bos taurus

Functional Description
(View)

Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.

Protein Sequence
(Fasta)

MSKPPPKPVK PGQVKVFRAL YTFEPRTPDE LYFEEGDIIY ITDMSDTNWW KGTCKGRTGL 60
IPSNYVAEQA ESIDNPLHEA AKRGNLSWLR ECLDNRVGVN GLDKAGSTAL YWACHGGHRD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACACAGGT CCCTGAAGGG GCACCGCGGC AAAGCAGACA AAAAGAAACT GAGGCGCTCA 60
GAGTGTCGGC TGGAGGCGCG TTTGGCTGAC TTTTCGTGCG TAGTCTTCAG AATCAGCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001452--SH3_domain

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50002--SH3

Pfam

PF12796--Ank_2
PF00018--SH3_1

PRINTS

PR01415--ANKYRIN
PR00452--SH3DOMAIN

SMART

SM00248--ANK
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome

KEGG

bta:281961

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001728	Ailuropoda melanoleuca	95.45	1.00e-112	398.00
IUUC-Apl-003751	Anas platyrhynchos	87.44	5.00e-106	376.00
IUUC-Aca-004876	Anolis carolinensis	90.65	7.00e-111	392.00
IUUC-Cel-018470	Caenorhabditis elegans	48.78	2.00e-50	192.00
IUUC-Cja-019917	Callithrix jacchus	97.98	1.00e-114	405.00
IUUC-Cfa-020190	Canis familiaris	97.34	1.00e-107	381.00
IUUC-Cpo-021650	Cavia porcellus	95.96	3.00e-112	397.00
IUUC-Csa-023311	Chlorocebus sabaeus	97.47	2.00e-114	404.00
IUUC-Cho-025043	Choloepus hoffmanni	87.62	2.00e-103	368.00
IUUC-Cin-025298	Ciona intestinalis	57.06	1.00e-54	205.00
IUUC-Csv-025890	Ciona savignyi	57.64	2.00e-61	228.00
IUUC-Dre-028036	Danio rerio	81.69	6.00e-101	359.00
IUUC-Dno-029567	Dasypus novemcinctus	97.47	4.00e-114	403.00
IUUC-Dor-031060	Dipodomys ordii	96.97	7.00e-114	402.00
IUUC-Eca-034406	Equus caballus	97.04	9.00e-117	412.00
IUUC-Fca-036234	Felis catus	97.77	1.00e-103	368.00
IUUC-Fal-037466	Ficedula albicollis	91.12	1.00e-111	394.00
IUUC-Gmo-039340	Gadus morhua	80.37	1.00e-101	362.00
IUUC-Gga-041127	Gallus gallus	90.65	1.00e-110	392.00
IUUC-Gac-042291	Gasterosteus aculeatus	78.97	2.00e-99	355.00
IUUC-Ggo-045142	Gorilla gorilla	96.97	2.00e-113	400.00
IUUC-Hsa-045670	Homo sapiens	96.97	2.00e-113	400.00
IUUC-Lch-050433	Latimeria chalumnae	86.92	2.00e-106	377.00
IUUC-Loc-052660	Lepisosteus oculatus	83.64	2.00e-105	375.00
IUUC-Laf-053692	Loxodonta africana	97.07	8.00e-117	412.00
IUUC-Mcc-054763	Macaca mulatta	97.47	2.00e-114	404.00
IUUC-Mga-059479	Meleagris gallopavo	91.05	5.00e-103	366.00
IUUC-Mmr-061426	Microcebus murinus	96.97	3.00e-114	403.00
IUUC-Mdo-062513	Monodelphis domestica	93.94	6.00e-112	395.00
IUUC-Mmu-063898	Mus musculus	95.48	4.00e-112	396.00
IUUC-Mpu-066606	Mustela putorius furo	96.45	3.00e-97	347.00
IUUC-Mlu-068187	Myotis lucifugus	94.15	2.00e-113	400.00
IUUC-Nle-069167	Nomascus leucogenys	97.47	2.00e-114	404.00
IUUC-Opr-070908	Ochotona princeps	96.53	1.00e-115	408.00
IUUC-Ont-072428	Oreochromis niloticus	82.24	4.00e-104	370.00
IUUC-Oan-072823	Ornithorhynchus anatinus	94.15	3.00e-114	403.00
IUUC-Ocu-074375	Oryctolagus cuniculus	97.47	2.00e-114	404.00
IUUC-Ola-086922	Oryzias latipes	81.78	4.00e-103	366.00
IUUC-Oga-088253	Otolemur garnettii	96.97	4.00e-114	403.00
IUUC-Oar-090217	Ovis aries	98.53	1.00e-117	415.00
IUUC-Ptr-091605	Pan troglodytes	96.97	2.00e-113	400.00
IUUC-Pan-092701	Papio anubis	97.47	2.00e-114	404.00
IUUC-Psi-093852	Pelodiscus sinensis	92.52	3.00e-114	403.00
IUUC-Pfo-096294	Poecilia formosa	79.91	1.00e-101	362.00
IUUC-Pva-102840	Pteropus vampyrus	75.70	9.00e-85	306.00
IUUC-Rno-105149	Rattus norvegicus	95.45	8.00e-113	399.00
IUUC-Sha-106884	Sarcophilus harrisii	92.68	3.00e-113	400.00
IUUC-Sja-107861	Schizosaccharomyces japonicus	36.63	2.00e-11	61.20
IUUC-Ssc-115549	Sus scrofa	97.47	3.00e-114	403.00
IUUC-Tgu-116709	Taeniopygia guttata	91.12	1.00e-111	394.00
IUUC-Tru-118367	Takifugu rubripes	82.71	2.00e-104	370.00
IUUC-Tni-120613	Tetraodon nigroviridis	81.78	1.00e-102	365.00
IUUC-Tbe-128089	Tupaia belangeri	80.98	3.00e-82	296.00
IUUC-Vpa-130041	Vicugna pacos	72.20	1.00e-79	288.00
IUUC-Xtr-132694	Xenopus tropicalis	85.64	4.00e-103	367.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence