iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	TRANSFAC	RAID2
Protein-protein Interaction
HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	PhosphositePlus	dbPTM	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	84.91	0.00e+00	1236.00	IUUC-Hsa-046965

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

Probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis.

Protein Sequence
(Fasta)

MGRARKPPPA LHRHCEGCFN RHCHVPVEPS VSCLVISCHL LCGATFHMCK ESEHTLLCPL 60
EQVPCLNSEY GCPLSMARHK LAKHLQVCPA SVVCCSMEWI RWPNVDSETF LHENIMKETP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGACCCTTCT TGCAAAGGCT TTCCTCCCTC CTCTGTGAAA CAAAGTCCGG GGTTGCTCTA 60
AGCGCTACTT TCCCATGGGC TCTCCTCTGC CCCTCCAGCA CTTAGACATT GAGTGTTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR031890--Fbxo30/Fbxo40
IPR008974--TRAF-like
IPR013083--Znf_RING/FYVE/PHD
IPR001293--Znf_TRAF

PROSITE

PS50181--FBOX
PS50145--ZF_TRAF

Pfam

PF15966--F-box_4
PF15965--zf-TRAF_2

Gene Ontology

GO:0005737--C:cytoplasm
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042692--P:muscle cell differentiation

KEGG

mmu:207215

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001882	Ailuropoda melanoleuca	83.47	0.00e+00	1140.00
IUUC-Apl-003788	Anas platyrhynchos	65.40	0.00e+00	889.00
IUUC-Aca-004624	Anolis carolinensis	60.60	0.00e+00	861.00
IUUC-Afl-008411	Aspergillus flavus	25.00	2.30e-02	32.00
IUUC-Ame-011599	Astyanax mexicanus	49.65	0.00e+00	708.00
IUUC-Bta-013376	Bos taurus	82.89	0.00e+00	1156.00
IUUC-Cja-019840	Callithrix jacchus	83.50	0.00e+00	1138.00
IUUC-Cfa-020146	Canis familiaris	83.10	0.00e+00	1149.00
IUUC-Cpo-021483	Cavia porcellus	82.34	0.00e+00	1186.00
IUUC-Csa-023141	Chlorocebus sabaeus	85.05	0.00e+00	1149.00
IUUC-Cho-024945	Choloepus hoffmanni	81.95	0.00e+00	1194.00
IUUC-Dre-027812	Danio rerio	44.54	5.00e-169	587.00
IUUC-Dno-030088	Dasypus novemcinctus	83.50	0.00e+00	1165.00
IUUC-Dor-030549	Dipodomys ordii	86.04	0.00e+00	1244.00
IUUC-Eca-034434	Equus caballus	85.07	0.00e+00	1186.00
IUUC-Eeu-035064	Erinaceus europaeus	81.64	0.00e+00	1168.00
IUUC-Fca-035523	Felis catus	80.26	0.00e+00	1116.00
IUUC-Fal-037137	Ficedula albicollis	63.92	0.00e+00	863.00
IUUC-Gmo-039031	Gadus morhua	46.25	1.00e-179	623.00
IUUC-Gga-040532	Gallus gallus	66.50	0.00e+00	751.00
IUUC-Gac-041371	Gasterosteus aculeatus	48.13	0.00e+00	650.00
IUUC-Gma-042970	Glycine max	24.15	2.00e-03	37.70
IUUC-Ggo-044453	Gorilla gorilla	84.77	0.00e+00	1176.00
IUUC-Hsa-046965	Homo sapiens	84.91	0.00e+00	1177.00
IUUC-Itr-048530	Ictidomys tridecemlineatus	84.17	0.00e+00	1194.00
IUUC-Lch-049573	Latimeria chalumnae	54.22	0.00e+00	798.00
IUUC-Loc-052475	Lepisosteus oculatus	53.52	0.00e+00	747.00
IUUC-Laf-054424	Loxodonta africana	81.88	0.00e+00	1192.00
IUUC-Mcc-055243	Macaca mulatta	85.05	0.00e+00	1151.00
IUUC-Meu-055909	Macropus eugenii	74.86	0.00e+00	1087.00
IUUC-Mga-060045	Meleagris gallopavo	64.91	0.00e+00	917.00
IUUC-Mmr-061531	Microcebus murinus	80.96	0.00e+00	1089.00
IUUC-Mdo-062838	Monodelphis domestica	76.17	0.00e+00	1075.00
IUUC-Mpu-066012	Mustela putorius furo	84.16	0.00e+00	1124.00
IUUC-Mlu-067170	Myotis lucifugus	83.90	0.00e+00	1178.00
IUUC-Nle-069819	Nomascus leucogenys	84.63	0.00e+00	1179.00
IUUC-Ont-072664	Oreochromis niloticus	47.51	0.00e+00	661.00
IUUC-Oan-072948	Ornithorhynchus anatinus	58.86	0.00e+00	769.00
IUUC-Ocu-074610	Oryctolagus cuniculus	84.32	0.00e+00	1245.00
IUUC-Ola-087480	Oryzias latipes	47.35	3.00e-180	625.00
IUUC-Oga-088445	Otolemur garnettii	83.33	0.00e+00	1183.00
IUUC-Oar-089876	Ovis aries	82.89	0.00e+00	1150.00
IUUC-Ptr-090727	Pan troglodytes	84.77	0.00e+00	1174.00
IUUC-Pan-092488	Papio anubis	85.05	0.00e+00	1154.00
IUUC-Psi-093321	Pelodiscus sinensis	64.15	0.00e+00	806.00
IUUC-Pno-095023	Phaeosphaeria nodorum	31.88	8.00e-04	38.90
IUUC-Pfo-097321	Poecilia formosa	48.50	0.00e+00	659.00
IUUC-Pab-097637	Pongo abelii	84.77	0.00e+00	1176.00
IUUC-Pca-100632	Procavia capensis	82.39	0.00e+00	857.00
IUUC-Pva-102503	Pteropus vampyrus	81.72	0.00e+00	1157.00
IUUC-Ptt-103857	Puccinia triticina	38.89	7.10e-02	32.00
IUUC-Rno-105321	Rattus norvegicus	93.94	0.00e+00	1320.00
IUUC-Sha-106906	Sarcophilus harrisii	74.37	0.00e+00	1044.00
IUUC-Sar-113603	Sorex araneus	81.81	0.00e+00	1177.00
IUUC-Ssc-116153	Sus scrofa	84.77	0.00e+00	801.00
IUUC-Tgu-117476	Taeniopygia guttata	63.31	0.00e+00	862.00
IUUC-Tru-118371	Takifugu rubripes	45.10	1.00e-170	593.00
IUUC-Tsy-118977	Tarsius syrichta	66.09	1.00e-124	440.00
IUUC-Tni-119795	Tetraodon nigroviridis	47.06	5.00e-176	611.00
IUUC-Tbe-127246	Tupaia belangeri	84.63	0.00e+00	1203.00
IUUC-Ttr-128674	Tursiops truncatus	80.35	0.00e+00	1060.00
IUUC-Vpa-130395	Vicugna pacos	79.27	0.00e+00	1094.00
IUUC-Xtr-132899	Xenopus tropicalis	55.65	0.00e+00	794.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence