iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106984

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01178348

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000004639.1	ENSSHAT00000005360.1	ENSSHAP00000005307.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-33	111.8	376	415
UBD/Beta-Prp	2.70e-63	214.1	287	575

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 376  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 415
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           ++++h++ +++v+fsp+++llatg++d+++k+w+v+  k+    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   htl+
   Q: 287  VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDKCeaKGSLSGSNAGITSIEFDSAGSYLLASSNDFASRIWTVDDNRLRHTLT 375
           5799************************************88899******************************************** PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd+++++++r+l+    
   Q: 376  GHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRSESIIRELE--LL 458
           ***************************************9999988....888888889*************************6..69 PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhns 265
           ++++ l++++++++l+s+s+d  +k+ dl+ + + +t+ +      +  ++v fsp++ +++ gs++gs++iW++ +g++ k+l++++s
   Q: 459  GKITALDLNPERTDLLSCSRDDLLKIIDLRVNAVKQTFSAPGfkcgSDWTRVVFSPDGSYIAAGSAEGSLYIWNVLTGKVEKVLSKQHS 547
           ******************************9999888888877777677779************************************* PP
   S: 266  svisvavlsfgdnvlvlgsedskvniwk 293
           s+i   ++s+++  +v++++ +k+ +w+
   Q: 548  SSINAVAWSPSGTQVVSVDKGNKAILWS 575
           ********************98988886 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

LEFLVLTDNK LLEKSDLQSV LADKLQAEKY DLQGRHEDLS PGHDGMWNDA QLQEMAQLRI 60
KHQEELTELH KKRGELAQSV IDLNNQMQQK DREMQMNEAK IAECLQKISE LETECQELRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGAATTTC TTGTTCTGAC AGATAATAAG TTGCTGGAGA AATCAGATCT TCAGTCGGTG 60
TTGGCTGATA AATTACAAGC AGAAAAATAT GATTTGCAAG GAAGGCACGA GATCAGGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	23.80	4.00e-34	139.00
IUUC-Aml-002242	Ailuropoda melanoleuca	87.41	0.00e+00	1003.00
IUUC-Atr-003073	Amborella trichopoda	24.20	4.00e-30	125.00
IUUC-Apl-003384	Anas platyrhynchos	87.89	0.00e+00	1061.00
IUUC-Aca-004962	Anolis carolinensis	84.82	0.00e+00	999.00
IUUC-Aly-005435	Arabidopsis lyrata	28.34	3.00e-45	176.00
IUUC-Ath-006948	Arabidopsis thaliana	27.16	5.00e-47	182.00
IUUC-Ame-010915	Astyanax mexicanus	77.85	8.00e-152	529.00
IUUC-Bta-012388	Bos taurus	87.52	0.00e+00	1052.00
IUUC-Bdi-014231	Brachypodium distachyon	25.81	8.00e-40	157.00
IUUC-Bol-016174	Brassica oleracea	33.33	8.00e-46	177.00
IUUC-Bra-017165	Brassica rapa	32.79	4.00e-45	176.00
IUUC-Cel-018131	Caenorhabditis elegans	30.91	2.00e-64	239.00
IUUC-Cja-018898	Callithrix jacchus	79.59	0.00e+00	889.00
IUUC-Cfa-020484	Canis familiaris	90.81	0.00e+00	1064.00
IUUC-Cpo-022156	Cavia porcellus	88.04	0.00e+00	1024.00
IUUC-Csa-024019	Chlorocebus sabaeus	87.35	0.00e+00	1004.00
IUUC-Cho-024311	Choloepus hoffmanni	74.92	0.00e+00	875.00
IUUC-Cin-025260	Ciona intestinalis	37.31	3.00e-99	355.00
IUUC-Csv-025836	Ciona savignyi	44.93	4.00e-49	187.00
IUUC-Dre-027702	Danio rerio	73.57	0.00e+00	871.00
IUUC-Dno-029728	Dasypus novemcinctus	86.36	0.00e+00	1059.00
IUUC-Dor-030587	Dipodomys ordii	87.85	3.00e-98	352.00
IUUC-Dme-031595	Drosophila melanogaster	40.60	6.00e-108	384.00
IUUC-Ete-032969	Echinops telfairi	74.70	0.00e+00	763.00
IUUC-Eca-034214	Equus caballus	92.89	0.00e+00	927.00
IUUC-Eeu-034537	Erinaceus europaeus	86.23	0.00e+00	885.00
IUUC-Fca-036005	Felis catus	88.66	0.00e+00	1037.00
IUUC-Fal-037593	Ficedula albicollis	86.50	0.00e+00	1014.00
IUUC-Gmo-039042	Gadus morhua	63.49	0.00e+00	662.00
IUUC-Gga-040986	Gallus gallus	86.00	0.00e+00	1043.00
IUUC-Gac-041351	Gasterosteus aculeatus	72.37	0.00e+00	879.00
IUUC-Gma-043265	Glycine max	28.87	3.00e-52	199.00
IUUC-Ggo-045427	Gorilla gorilla	87.37	0.00e+00	1023.00
IUUC-Hsa-046632	Homo sapiens	89.77	0.00e+00	1044.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	85.47	0.00e+00	988.00
IUUC-Lch-049439	Latimeria chalumnae	50.59	4.00e-141	494.00
IUUC-Lpe-051254	Leersia perrieri	25.19	1.00e-40	160.00
IUUC-Loc-052610	Lepisosteus oculatus	74.70	0.00e+00	879.00
IUUC-Laf-053936	Loxodonta africana	84.42	0.00e+00	1016.00
IUUC-Mcc-055504	Macaca mulatta	84.49	0.00e+00	1040.00
IUUC-Meu-056516	Macropus eugenii	86.53	0.00e+00	1011.00
IUUC-Mtr-058062	Medicago truncatula	26.06	7.00e-47	181.00
IUUC-Mga-059777	Meleagris gallopavo	88.73	0.00e+00	1063.00
IUUC-Mmr-061298	Microcebus murinus	88.03	0.00e+00	1035.00
IUUC-Mdo-062969	Monodelphis domestica	93.17	0.00e+00	1104.00
IUUC-Mmu-064076	Mus musculus	85.64	0.00e+00	1008.00
IUUC-Mac-065161	Musa acuminata	25.29	7.00e-41	161.00
IUUC-Mpu-066196	Mustela putorius furo	88.03	0.00e+00	1035.00
IUUC-Mlu-067651	Myotis lucifugus	89.60	0.00e+00	1053.00
IUUC-Nle-069853	Nomascus leucogenys	88.21	0.00e+00	1026.00
IUUC-Opr-070350	Ochotona princeps	90.73	2.00e-115	409.00
IUUC-Ont-072489	Oreochromis niloticus	72.56	0.00e+00	876.00
IUUC-Oan-072703	Ornithorhynchus anatinus	82.72	0.00e+00	962.00
IUUC-Ocu-074205	Oryctolagus cuniculus	86.00	0.00e+00	1030.00
IUUC-Oba-075619	Oryza barthii	24.41	4.00e-38	152.00
IUUC-Obr-076632	Oryza brachyantha	29.32	5.00e-37	149.00
IUUC-Ogl-077671	Oryza glaberrima	24.41	4.00e-38	152.00
IUUC-Ogu-078052	Oryza glumaepatula	24.61	3.00e-38	152.00
IUUC-Oin-079611	Oryza indica	24.22	6.00e-36	145.00
IUUC-Olo-080408	Oryza longistaminata	25.51	2.00e-35	143.00
IUUC-Ome-081560	Oryza meridionalis	24.61	2.00e-38	153.00
IUUC-Oni-082145	Oryza nivara	24.41	4.00e-38	152.00
IUUC-Opu-083918	Oryza punctata	29.24	6.00e-35	142.00
IUUC-Oru-084858	Oryza rufipogon	24.22	9.00e-36	144.00
IUUC-Osa-086277	Oryza sativa	24.22	7.00e-36	145.00
IUUC-Ola-086816	Oryzias latipes	71.48	1.00e-98	352.00
IUUC-Olu-087622	Ostreococcus lucimarinus	34.33	3.00e-45	175.00
IUUC-Oga-088765	Otolemur garnettii	86.66	0.00e+00	965.00
IUUC-Oar-090196	Ovis aries	85.56	0.00e+00	962.00
IUUC-Ptr-091676	Pan troglodytes	89.95	0.00e+00	1046.00
IUUC-Pan-092068	Papio anubis	88.05	0.00e+00	1032.00
IUUC-Psi-093367	Pelodiscus sinensis	88.21	0.00e+00	1026.00
IUUC-Ppa-095699	Physcomitrella patens	29.53	2.00e-43	169.00
IUUC-Pfo-096067	Poecilia formosa	73.01	0.00e+00	853.00
IUUC-Pab-098111	Pongo abelii	87.37	0.00e+00	1023.00
IUUC-Pop-099116	Populus trichocarpa	31.92	2.00e-43	169.00
IUUC-Pca-100680	Procavia capensis	75.80	0.00e+00	827.00
IUUC-Ppe-101790	Prunus persica	24.90	3.00e-44	172.00
IUUC-Pva-102871	Pteropus vampyrus	86.54	0.00e+00	1004.00
IUUC-Rno-106088	Rattus norvegicus	85.14	0.00e+00	1003.00
IUUC-Smo-109404	Selaginella moellendorffii	25.97	9.00e-45	174.00
IUUC-Sit-110828	Setaria italica	26.77	1.00e-44	174.00
IUUC-Sly-111009	Solanum lycopersicum	25.53	1.00e-47	184.00
IUUC-Stu-112370	Solanum tuberosum	26.01	3.00e-49	189.00
IUUC-Sar-113659	Sorex araneus	61.49	1.00e-86	312.00
IUUC-Sbi-114819	Sorghum bicolor	25.43	3.00e-40	159.00
IUUC-Ssc-116241	Sus scrofa	87.46	0.00e+00	1016.00
IUUC-Tgu-116576	Taeniopygia guttata	88.04	0.00e+00	1066.00
IUUC-Tru-118336	Takifugu rubripes	65.03	0.00e+00	727.00
IUUC-Tsy-119006	Tarsius syrichta	83.64	0.00e+00	973.00
IUUC-Tni-120300	Tetraodon nigroviridis	74.74	0.00e+00	858.00
IUUC-Tca-121002	Theobroma cacao	27.55	4.00e-50	192.00
IUUC-Tae-124868	Triticum aestivum	24.18	7.00e-35	141.00
IUUC-Tur-126463	Triticum urartu	23.80	2.00e-34	140.00
IUUC-Tbe-127631	Tupaia belangeri	92.03	0.00e+00	894.00
IUUC-Ttr-129005	Tursiops truncatus	81.11	5.00e-157	547.00
IUUC-Vpa-130246	Vicugna pacos	78.71	0.00e+00	759.00
IUUC-Vvi-130878	Vitis vinifera	33.65	6.00e-45	175.00
IUUC-Xtr-132798	Xenopus tropicalis	75.99	0.00e+00	872.00
IUUC-Xma-133264	Xiphophorus maculatus	72.62	0.00e+00	855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence