iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028774

UUCD1 version

UUC-DaR-01346

Ensembl Protein ID

ENSDARP00000021303.7

UniProt Accession

Q803M4; Q803M4_DANRE

Genbank Protein ID

AAH44416.1; AAI64899.1

Protein Name

Ubiquitin-conjugating enzyme E2 A,-like; Zgc:55512; Zgc:55512 protein

Genbank Nucleotide ID

BX537313; BC164899

Gene Name

ube2al; zgc:55512

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000003017.8	ENSDART00000008490.8	ENSDARP00000021303.7

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.30e-54	184.7	8	142

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++++k+l++dpp+g+s  p+++ +++ w+++i+Gpe+tp+e+g+Fkl++ef+e+YP kPP+v+f++k+fhPnvy++G++Cl+il+  
   Q: 8    RLMRDFKRLQEDPPAGVSGAPSEN-NIMVWNAVIFGPEGTPFEDGTFKLTVEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQ-- 93
           9**********************9.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 94   NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 142
           **********************************************996 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSTPARRRLM RDFKRLQEDP PAGVSGAPSE NNIMVWNAVI FGPEGTPFED GTFKLTVEFT 60
EEYPNKPPTV RFVSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGACAAAT AGGGGGACTT GTGACGTTTA CGTAGCGCTT GACAAACATT TTACTTAAAT 60
TCTCGAATTA TTTCCATTAA CTCAAAATAT TTCAAACAAC TATTAGAATA TTGATCACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0016574--P:histone ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

dre:325470

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002120	Ailuropoda melanoleuca	95.39	9.00e-85	305.00
IUUC-Atr-002862	Amborella trichopoda	79.19	5.00e-72	263.00
IUUC-Apl-004063	Anas platyrhynchos	87.92	2.00e-73	267.00
IUUC-Aca-005001	Anolis carolinensis	95.39	1.00e-84	305.00
IUUC-Aly-005584	Arabidopsis lyrata	77.18	7.00e-71	259.00
IUUC-Ath-007149	Arabidopsis thaliana	77.18	7.00e-71	259.00
IUUC-Ame-010844	Astyanax mexicanus	99.34	4.00e-88	316.00
IUUC-Bgr-012039	Blumeria graminis	66.91	2.00e-56	211.00
IUUC-Bta-012840	Bos taurus	95.39	9.00e-85	305.00
IUUC-Bdi-015010	Brachypodium distachyon	78.52	3.00e-71	260.00
IUUC-Cre-022822	Chlamydomonas reinhardtii	75.19	3.00e-57	214.00
IUUC-Cho-024773	Choloepus hoffmanni	77.63	5.00e-63	233.00
IUUC-Cne-026864	Cryptococcus neoformans	71.81	4.00e-65	240.00
IUUC-Dno-029661	Dasypus novemcinctus	95.39	9.00e-85	305.00
IUUC-Dor-030452	Dipodomys ordii	94.89	2.00e-75	273.00
IUUC-Ete-032595	Echinops telfairi	92.11	4.00e-82	296.00
IUUC-Gac-042471	Gasterosteus aculeatus	98.68	4.00e-87	313.00
IUUC-Gma-043883	Glycine max	79.19	5.00e-72	263.00
IUUC-Mor-057087	Magnaporthe oryzae	67.16	2.00e-54	204.00
IUUC-Mmr-060630	Microcebus murinus	95.39	9.00e-85	305.00
IUUC-Mac-064774	Musa acuminata	79.19	9.00e-72	262.00
IUUC-Mpu-065803	Mustela putorius furo	95.39	9.00e-85	305.00
IUUC-Mlu-067147	Myotis lucifugus	95.39	9.00e-85	305.00
IUUC-Opr-070935	Ochotona princeps	95.39	9.00e-85	305.00
IUUC-Ont-071335	Oreochromis niloticus	99.34	1.00e-87	314.00
IUUC-Oan-072706	Ornithorhynchus anatinus	89.93	2.00e-77	280.00
IUUC-Ola-087160	Oryzias latipes	99.34	1.00e-87	314.00
IUUC-Olu-087830	Ostreococcus lucimarinus	79.19	2.00e-62	231.00
IUUC-Oar-090141	Ovis aries	95.39	9.00e-85	305.00
IUUC-Pma-094376	Petromyzon marinus	96.05	7.00e-86	308.00
IUUC-Pop-099517	Populus trichocarpa	79.19	5.00e-72	263.00
IUUC-Ppe-101949	Prunus persica	79.19	9.00e-72	263.00
IUUC-Sce-106283	Saccharomyces cerevisiae	69.80	1.00e-62	232.00
IUUC-Sha-107650	Sarcophilus harrisii	94.08	7.00e-83	298.00
IUUC-Sar-113429	Sorex araneus	95.39	9.00e-85	305.00
IUUC-Tsy-119000	Tarsius syrichta	95.39	9.00e-85	305.00
IUUC-Tca-121827	Theobroma cacao	78.52	7.00e-72	262.00
IUUC-Tbe-127921	Tupaia belangeri	93.42	3.00e-80	290.00
IUUC-Xma-133667	Xiphophorus maculatus	99.34	1.00e-87	314.00
IUUC-Zma-135584	Zea mays	77.18	2.00e-70	258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence