iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072952

UUCD1 version

UUC-OrA-00298

Ensembl Protein ID

ENSOANP00000009707.1

UniProt Accession

F6XQZ8; F6XQZ8_ORNAN

Protein Name

Uncharacterized protein

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006090.2	ENSOANT00000009709.2	ENSOANP00000009707.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-22	78.8	367	398
UBD/Beta-Prp	2.00e-45	155.5	280	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 280  KSHQGVVIAADWLVGGKQTVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 368
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 369  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQRIIALPHDNRQVRLFDMsgvRLARLPRSNRQGH 455
           ******99999.********************988874555555.55555555558*****************777778888888888* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 456  RRMVCCSAWSEDHpiCNLFTCGFDRQAIGWNIN 488
           ************9777899***********986 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MPTESGSCAT ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQDSKL PSSVRNTLLE 60
LFGQIEREFE NLYIENLELR REIETLNERL TAEGQTIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCACAG AAAGCGGAAG CTGTGCAACT GCTCGCCAAG CCAAGCAGAA ACGCAAGTCT 60
CATAGCCTCT CTATACGAAG AACCAACAGC TCGGAACAAG AAAGGACGGG CCTGCCAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	93.75	0.00e+00	947.00
IUUC-Apl-003647	Anas platyrhynchos	95.77	0.00e+00	950.00
IUUC-Aca-004759	Anolis carolinensis	95.56	0.00e+00	967.00
IUUC-Ame-011103	Astyanax mexicanus	56.55	1.00e-145	508.00
IUUC-Bta-012718	Bos taurus	93.35	0.00e+00	943.00
IUUC-Cel-018499	Caenorhabditis elegans	42.12	2.00e-97	348.00
IUUC-Cja-019492	Callithrix jacchus	93.95	0.00e+00	969.00
IUUC-Cfa-020199	Canis familiaris	93.15	0.00e+00	970.00
IUUC-Cpo-022500	Cavia porcellus	88.51	0.00e+00	921.00
IUUC-Csa-023567	Chlorocebus sabaeus	94.76	0.00e+00	977.00
IUUC-Cho-025071	Choloepus hoffmanni	68.35	0.00e+00	644.00
IUUC-Cin-025460	Ciona intestinalis	45.51	4.00e-105	374.00
IUUC-Csv-026042	Ciona savignyi	46.21	1.00e-107	382.00
IUUC-Dre-028214	Danio rerio	83.87	0.00e+00	877.00
IUUC-Dno-029826	Dasypus novemcinctus	95.90	0.00e+00	830.00
IUUC-Dor-030967	Dipodomys ordii	94.26	0.00e+00	876.00
IUUC-Dme-031936	Drosophila melanogaster	49.26	2.00e-118	419.00
IUUC-Ete-032452	Echinops telfairi	91.94	0.00e+00	946.00
IUUC-Eca-033278	Equus caballus	94.35	0.00e+00	980.00
IUUC-Eeu-034592	Erinaceus europaeus	81.25	0.00e+00	810.00
IUUC-Fca-036431	Felis catus	93.96	0.00e+00	974.00
IUUC-Fal-037149	Ficedula albicollis	94.56	0.00e+00	943.00
IUUC-Gmo-038476	Gadus morhua	81.31	0.00e+00	781.00
IUUC-Gga-041099	Gallus gallus	95.56	0.00e+00	952.00
IUUC-Gac-042374	Gasterosteus aculeatus	85.80	0.00e+00	837.00
IUUC-Ggo-044683	Gorilla gorilla	87.30	0.00e+00	888.00
IUUC-Hsa-046658	Homo sapiens	94.35	0.00e+00	972.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	95.38	0.00e+00	909.00
IUUC-Lch-050571	Latimeria chalumnae	86.15	0.00e+00	897.00
IUUC-Loc-052652	Lepisosteus oculatus	83.21	0.00e+00	873.00
IUUC-Laf-053712	Loxodonta africana	94.39	0.00e+00	975.00
IUUC-Mcc-055521	Macaca mulatta	94.76	0.00e+00	977.00
IUUC-Meu-056324	Macropus eugenii	92.74	0.00e+00	908.00
IUUC-Mga-060114	Meleagris gallopavo	95.77	0.00e+00	958.00
IUUC-Mmr-061176	Microcebus murinus	94.35	0.00e+00	972.00
IUUC-Mdo-061888	Monodelphis domestica	96.98	0.00e+00	944.00
IUUC-Mmu-063977	Mus musculus	95.16	0.00e+00	988.00
IUUC-Mpu-066220	Mustela putorius furo	81.28	7.00e-177	612.00
IUUC-Mlu-068155	Myotis lucifugus	94.35	0.00e+00	980.00
IUUC-Nle-069964	Nomascus leucogenys	94.56	0.00e+00	974.00
IUUC-Opr-070925	Ochotona princeps	90.94	1.00e-144	505.00
IUUC-Ont-071317	Oreochromis niloticus	87.70	0.00e+00	865.00
IUUC-Ocu-073913	Oryctolagus cuniculus	95.16	0.00e+00	987.00
IUUC-Ola-087024	Oryzias latipes	85.92	0.00e+00	897.00
IUUC-Oga-087945	Otolemur garnettii	93.55	0.00e+00	976.00
IUUC-Oar-089854	Ovis aries	93.35	0.00e+00	937.00
IUUC-Ptr-091486	Pan troglodytes	94.56	0.00e+00	974.00
IUUC-Pan-091738	Papio anubis	94.76	0.00e+00	977.00
IUUC-Psi-093953	Pelodiscus sinensis	96.17	0.00e+00	961.00
IUUC-Pma-094560	Petromyzon marinus	74.46	0.00e+00	777.00
IUUC-Pfo-097222	Poecilia formosa	83.27	0.00e+00	833.00
IUUC-Pab-098778	Pongo abelii	89.92	0.00e+00	914.00
IUUC-Pca-100852	Procavia capensis	91.13	0.00e+00	924.00
IUUC-Pva-103130	Pteropus vampyrus	92.56	4.00e-132	464.00
IUUC-Rno-105848	Rattus norvegicus	86.29	0.00e+00	872.00
IUUC-Sha-106750	Sarcophilus harrisii	97.38	0.00e+00	973.00
IUUC-Sar-113749	Sorex araneus	85.48	0.00e+00	862.00
IUUC-Ssc-115691	Sus scrofa	92.34	0.00e+00	922.00
IUUC-Tgu-117365	Taeniopygia guttata	94.35	0.00e+00	899.00
IUUC-Tru-117595	Takifugu rubripes	85.08	0.00e+00	843.00
IUUC-Tsy-118973	Tarsius syrichta	73.08	8.00e-148	516.00
IUUC-Tni-120545	Tetraodon nigroviridis	84.34	0.00e+00	877.00
IUUC-Tbe-127976	Tupaia belangeri	71.57	0.00e+00	687.00
IUUC-Ttr-128472	Tursiops truncatus	91.13	0.00e+00	933.00
IUUC-Xtr-132621	Xenopus tropicalis	92.74	0.00e+00	918.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence