iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012581

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Anaphase-promoting complex subunit CDC26; Cell division cycle protein 26 homolog

Genbank Nucleotide ID

BC102716

Gene Name

CDC26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000014430.2	ENSBTAT00000019191.2	ENSBTAP00000019191.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C	94.12	4.00e-41	163.00	IUUC-Hsa-046899

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Functional Description
(View)

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity).

Protein Sequence
(Fasta)

MLRRKPTRLE LKLDDIEEFE SIRKDLETRK KQKEDVDIVG GSDGEGAIGL SSDPKSREQM 60
INDRIGYKPQ PKPNNRSSQF GNFEF 85

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Nucleotide Sequence
(Fasta)

GATATGATCT GCAGAGCCTC CGAGAAAAGC ACGCGGAGGA CAAGGTTCTG CGAAGAGAGA 60
GACTCAGAGG CAGTGTGGGA AGTGTAGTCC AGTTGGCTTA GCGGATGATT CGGGGTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0498--Mitosis
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR018860--APC_suCDC26

Pfam

PF10471--ANAPC_CDC26

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0070979--P:protein K11-linked ubiquitination
GO:0030071--P:regulation of mitotic metaphase/anaphase transition

KEGG

bta:777693

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001456	Ailuropoda melanoleuca	95.29	1.00e-42	163.00
IUUC-Atr-002458	Amborella trichopoda	35.71	2.00e-03	33.50
IUUC-Aca-004376	Anolis carolinensis	83.53	5.00e-38	148.00
IUUC-Ago-007754	Ashbya gossypii	31.91	3.80e-01	26.60
IUUC-Acl-008116	Aspergillus clavatus	52.17	8.00e-02	28.10
IUUC-Afl-008653	Aspergillus flavus	33.33	9.40e-01	27.70
IUUC-Ani-009376	Aspergillus nidulans	46.67	4.30e-01	25.80
IUUC-Ame-011022	Astyanax mexicanus	59.77	5.00e-24	102.00
IUUC-Bci-013595	Botrytis cinerea	50.00	2.00e+00	25.00
IUUC-Cja-019622	Callithrix jacchus	92.94	3.00e-42	162.00
IUUC-Cfa-021044	Canis familiaris	95.29	1.00e-42	163.00
IUUC-Cpo-022441	Cavia porcellus	92.94	1.00e-35	140.00
IUUC-Csa-024091	Chlorocebus sabaeus	95.29	2.00e-34	136.00
IUUC-Cho-025001	Choloepus hoffmanni	87.93	1.00e-24	103.00
IUUC-Csv-025958	Ciona savignyi	26.14	9.00e-06	41.20
IUUC-Dre-027369	Danio rerio	64.77	6.00e-29	118.00
IUUC-Dno-029137	Dasypus novemcinctus	90.59	4.00e-41	158.00
IUUC-Dor-030181	Dipodomys ordii	95.29	2.00e-43	166.00
IUUC-Ete-032555	Echinops telfairi	94.12	4.00e-42	162.00
IUUC-Eca-033227	Equus caballus	94.12	3.00e-34	135.00
IUUC-Eeu-034615	Erinaceus europaeus	87.93	4.00e-26	108.00
IUUC-Fca-035838	Felis catus	92.94	2.00e-41	159.00
IUUC-Fal-036994	Ficedula albicollis	89.66	1.00e-09	53.90
IUUC-Gga-040675	Gallus gallus	64.71	8.00e-23	97.80
IUUC-Ggo-044779	Gorilla gorilla	93.10	5.00e-19	85.10
IUUC-Hsa-046899	Homo sapiens	94.12	6.00e-34	134.00
IUUC-Itr-048643	Ictidomys tridecemlineatus	95.29	3.00e-36	142.00
IUUC-Lch-049544	Latimeria chalumnae	68.24	7.00e-31	124.00
IUUC-Loc-052390	Lepisosteus oculatus	63.64	3.00e-24	102.00
IUUC-Laf-053681	Loxodonta africana	96.47	5.00e-35	138.00
IUUC-Mcc-054912	Macaca mulatta	95.29	2.00e-34	136.00
IUUC-Meu-056222	Macropus eugenii	84.48	2.00e-25	106.00
IUUC-Mor-057242	Magnaporthe oryzae	34.38	2.30e-01	28.50
IUUC-Mmr-061790	Microcebus murinus	91.76	6.00e-42	161.00
IUUC-Mmu-064350	Mus musculus	90.59	1.00e-39	153.00
IUUC-Mlu-067848	Myotis lucifugus	95.29	8.00e-36	140.00
IUUC-Nle-069077	Nomascus leucogenys	94.12	6.00e-34	134.00
IUUC-Opr-071004	Ochotona princeps	94.12	7.00e-36	141.00
IUUC-Ont-071525	Oreochromis niloticus	47.42	7.00e-17	78.20
IUUC-Oan-073200	Ornithorhynchus anatinus	92.94	6.00e-42	161.00
IUUC-Ocu-074476	Oryctolagus cuniculus	94.12	7.00e-43	164.00
IUUC-Oba-075520	Oryza barthii	65.00	4.40e-02	28.90
IUUC-Obr-076249	Oryza brachyantha	65.00	2.90e-01	28.50
IUUC-Ogu-078445	Oryza glumaepatula	65.00	4.50e-02	28.90
IUUC-Ola-087554	Oryzias latipes	48.42	4.00e-19	85.50
IUUC-Oga-088195	Otolemur garnettii	92.94	2.00e-32	129.00
IUUC-Oar-089399	Ovis aries	98.82	4.00e-44	168.00
IUUC-Ptr-090822	Pan troglodytes	94.12	6.00e-34	134.00
IUUC-Pan-092857	Papio anubis	95.29	2.00e-34	136.00
IUUC-Ppa-095794	Physcomitrella patens	75.00	6.00e-03	32.00
IUUC-Pfo-097147	Poecilia formosa	50.00	6.00e-16	74.70
IUUC-Pab-098774	Pongo abelii	94.12	6.00e-34	134.00
IUUC-Pca-100745	Procavia capensis	95.29	3.00e-34	135.00
IUUC-Pva-102647	Pteropus vampyrus	95.29	8.00e-36	140.00
IUUC-Pte-104296	Pyrenophora teres	54.17	7.70e-02	28.10
IUUC-Pyt-104747	Pyrenophora triticirepentis	54.17	6.00e-02	28.50
IUUC-Rno-106085	Rattus norvegicus	89.41	4.00e-39	151.00
IUUC-Sce-106324	Saccharomyces cerevisiae	47.37	6.40e-01	25.80
IUUC-Sha-107235	Sarcophilus harrisii	91.76	9.00e-42	160.00
IUUC-Spo-108195	Schizosaccharomyces pombe	28.95	4.80e-01	25.40
IUUC-Sar-113299	Sorex araneus	91.38	4.00e-19	85.50
IUUC-Ssc-115650	Sus scrofa	87.06	6.00e-31	124.00
IUUC-Tgu-117309	Taeniopygia guttata	61.63	5.00e-23	98.20
IUUC-Tsy-119267	Tarsius syrichta	96.47	5.00e-35	138.00
IUUC-Tni-120675	Tetraodon nigroviridis	52.94	5.00e-20	88.60
IUUC-Tvi-122490	Trichoderma virens	50.00	4.00e-01	26.90
IUUC-Ttr-129250	Tursiops truncatus	95.29	1.00e-35	140.00
IUUC-Vpa-130562	Vicugna pacos	96.47	5.00e-43	164.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence