iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026891

Ensembl Protein ID

AAW45343

UniProt Accession

P0CS38; Q55N02; Q5KBD1; Q5KBD2; HIR1_CRYNJ

Genbank Protein ID

AAW45342.1; AAW45343.1

Protein Name

Protein HIR1

Genbank Nucleotide ID

AE017349; AE017349

Gene Name

HIR1; CNI02950

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNI02950	AAW45342	AAW45342
CNI02950	AAW45343	AAW45343

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.70e-26	87.7	72	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           Ht+sv ++++ +  ++l++GsdD +i++W l
   Q: 72   HTGSVLSVRWaHHgRFLATGSDDQVIMIWGL 102
           9**********5559**************97 PP

Organism

Cryptococcus neoformans

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MKVTKPNWVE HTVGEKKAKT AIYSISVHPD GTRLATGGLD HKVKIWSTLP ILDVEAEKEE 60
ENPKLLCTMS SHTGSVLSVR WAHHGRFLAT GSDDQVIMIW GLDPDGGGRL WGSDEINVEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTACAGCGA AGTTCGTGAA TACCGTGTAT TTCACTTCTT CCTCTGTAAC TTTCCAAGGA 60
AGAGGATAAC TGTGAGAAGG GTATTATGAA GGTTACCAAG CCCAACTGGG TGGAACATAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000417--C:HIR complex
GO:0000790--C:nuclear chromatin
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated

KEGG

cne:CNI02950

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	38.28	4.00e-74	271.00
IUUC-Aml-001723	Ailuropoda melanoleuca	41.55	1.00e-75	276.00
IUUC-Atr-003132	Amborella trichopoda	39.17	7.00e-77	280.00
IUUC-Apl-003197	Anas platyrhynchos	41.71	1.00e-76	280.00
IUUC-Aca-004733	Anolis carolinensis	39.46	5.00e-78	284.00
IUUC-Aly-005446	Arabidopsis lyrata	38.46	5.00e-78	284.00
IUUC-Ath-007627	Arabidopsis thaliana	29.22	2.00e-88	318.00
IUUC-Ago-007766	Ashbya gossypii	37.31	4.00e-77	281.00
IUUC-Acl-008104	Aspergillus clavatus	40.21	1.00e-85	309.00
IUUC-Afl-008591	Aspergillus flavus	39.36	1.00e-84	306.00
IUUC-Afu-008781	Aspergillus fumigatus	40.52	5.00e-77	280.00
IUUC-Ani-009272	Aspergillus nidulans	36.67	4.00e-73	267.00
IUUC-Ang-009655	Aspergillus niger	40.00	4.00e-87	314.00
IUUC-Aor-010119	Aspergillus oryzae	39.36	1.00e-84	306.00
IUUC-Ate-010530	Aspergillus terreus	36.02	1.00e-72	266.00
IUUC-Bgr-012237	Blumeria graminis	40.75	5.00e-83	301.00
IUUC-Bta-013320	Bos taurus	41.24	6.00e-76	277.00
IUUC-Bci-013795	Botrytis cinerea	39.51	1.00e-84	306.00
IUUC-Bdi-014075	Brachypodium distachyon	41.21	7.00e-79	286.00
IUUC-Bol-016440	Brassica oleracea	39.66	2.00e-82	298.00
IUUC-Bra-016651	Brassica rapa	39.32	5.00e-82	297.00
IUUC-Cel-018692	Caenorhabditis elegans	32.74	1.00e-49	189.00
IUUC-Cja-018987	Callithrix jacchus	39.31	2.00e-67	248.00
IUUC-Cfa-020132	Canis familiaris	41.55	1.00e-75	276.00
IUUC-Cpo-021484	Cavia porcellus	41.08	1.00e-78	286.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	32.64	1.00e-58	219.00
IUUC-Csa-023081	Chlorocebus sabaeus	41.08	2.00e-78	285.00
IUUC-Cin-025182	Ciona intestinalis	38.83	1.00e-79	290.00
IUUC-Csv-026154	Ciona savignyi	40.00	7.00e-75	273.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	42.86	7.00e-89	320.00
IUUC-Cme-027349	Cyanidioschyzon merolae	29.53	5.00e-39	154.00
IUUC-Dre-027655	Danio rerio	39.73	2.00e-78	285.00
IUUC-Dno-029557	Dasypus novemcinctus	40.48	7.00e-60	223.00
IUUC-Dor-030687	Dipodomys ordii	35.97	2.00e-62	231.00
IUUC-Dse-031334	Dothistroma septosporum	42.11	2.00e-85	308.00
IUUC-Dme-031746	Drosophila melanogaster	37.84	1.00e-83	302.00
IUUC-Ete-032384	Echinops telfairi	36.68	6.00e-57	214.00
IUUC-Eca-033430	Equus caballus	41.26	1.00e-75	276.00
IUUC-Fca-036121	Felis catus	41.55	8.00e-76	276.00
IUUC-Fal-036817	Ficedula albicollis	41.71	1.00e-76	279.00
IUUC-Fox-037906	Fusarium oxysporum	42.42	1.00e-87	315.00
IUUC-Fso-038409	Fusarium solani	39.33	1.00e-86	312.00
IUUC-Gmo-039151	Gadus morhua	39.78	9.00e-81	293.00
IUUC-Ggr-040016	Gaeumannomyces graminis	41.29	4.00e-88	317.00
IUUC-Gga-040936	Gallus gallus	41.24	2.00e-79	288.00
IUUC-Gac-041405	Gasterosteus aculeatus	38.11	6.00e-74	270.00
IUUC-Gma-042800	Glycine max	28.97	1.00e-93	336.00
IUUC-Ggo-045430	Gorilla gorilla	41.08	1.00e-78	286.00
IUUC-Hsa-046442	Homo sapiens	41.08	1.00e-78	286.00
IUUC-Hvu-047587	Hordeum vulgare	42.11	3.00e-69	254.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	42.76	1.00e-63	234.00
IUUC-Kpa-049145	Komagataella pastoris	38.15	3.00e-81	295.00
IUUC-Lch-050474	Latimeria chalumnae	39.73	1.00e-79	289.00
IUUC-Lpe-051209	Leersia perrieri	40.45	2.00e-73	268.00
IUUC-Loc-052119	Lepisosteus oculatus	39.73	6.00e-79	287.00
IUUC-Lma-053237	Leptosphaeria maculans	40.91	1.00e-84	306.00
IUUC-Laf-053718	Loxodonta africana	41.35	1.00e-78	286.00
IUUC-Mcc-055621	Macaca mulatta	40.88	2.00e-67	249.00
IUUC-Meu-055914	Macropus eugenii	37.78	5.00e-60	224.00
IUUC-Mor-057090	Magnaporthe oryzae	41.44	1.00e-86	312.00
IUUC-Mpo-057364	Magnaporthe poae	41.56	2.00e-88	319.00
IUUC-Mtr-058691	Medicago truncatula	40.39	7.00e-80	290.00
IUUC-Mla-058914	Melampsora laricipopulina	34.24	5.00e-133	466.00
IUUC-Mga-060181	Meleagris gallopavo	41.71	7.00e-77	280.00
IUUC-Mvi-060432	Microbotryum violaceum	46.01	5.00e-100	357.00
IUUC-Mmr-060871	Microcebus murinus	41.08	1.00e-78	286.00
IUUC-Mdo-062301	Monodelphis domestica	39.73	4.00e-78	284.00
IUUC-Mmu-063888	Mus musculus	39.73	3.00e-78	285.00
IUUC-Mac-065137	Musa acuminata	30.09	8.00e-97	346.00
IUUC-Mpu-066732	Mustela putorius furo	41.55	7.00e-76	276.00
IUUC-Mlu-067542	Myotis lucifugus	41.55	9.00e-76	276.00
IUUC-Nfi-068396	Neosartorya fischeri	40.52	4.00e-77	281.00
IUUC-Ncr-068842	Neurospora crassa	41.31	1.00e-86	312.00
IUUC-Nle-070156	Nomascus leucogenys	41.08	1.00e-78	286.00
IUUC-Opr-070808	Ochotona princeps	41.56	2.00e-48	186.00
IUUC-Ont-072105	Oreochromis niloticus	38.65	1.00e-77	282.00
IUUC-Ocu-074962	Oryctolagus cuniculus	41.55	9.00e-76	276.00
IUUC-Oba-075178	Oryza barthii	40.95	2.00e-77	282.00
IUUC-Obr-076399	Oryza brachyantha	41.71	3.00e-79	288.00
IUUC-Ogu-078797	Oryza glumaepatula	40.95	2.00e-77	282.00
IUUC-Oin-080085	Oryza indica	41.81	3.00e-67	248.00
IUUC-Olo-081048	Oryza longistaminata	40.85	9.00e-55	207.00
IUUC-Ome-081324	Oryza meridionalis	40.95	2.00e-77	282.00
IUUC-Oni-082548	Oryza nivara	40.95	2.00e-77	281.00
IUUC-Opu-084008	Oryza punctata	41.71	2.00e-79	288.00
IUUC-Oru-084339	Oryza rufipogon	40.95	3.00e-77	281.00
IUUC-Osa-085782	Oryza sativa	40.95	3.00e-77	281.00
IUUC-Ola-087302	Oryzias latipes	35.75	3.00e-65	241.00
IUUC-Olu-087611	Ostreococcus lucimarinus	40.89	1.00e-87	315.00
IUUC-Oga-087935	Otolemur garnettii	41.55	9.00e-76	276.00
IUUC-Oar-089229	Ovis aries	36.11	2.00e-59	222.00
IUUC-Ptr-090715	Pan troglodytes	41.08	2.00e-78	285.00
IUUC-Pan-092318	Papio anubis	41.55	6.00e-76	277.00
IUUC-Psi-094053	Pelodiscus sinensis	40.32	5.00e-75	274.00
IUUC-Pno-094985	Phaeosphaeria nodorum	37.59	1.00e-76	279.00
IUUC-Ppa-095499	Physcomitrella patens	40.19	3.00e-79	288.00
IUUC-Pfo-096857	Poecilia formosa	38.27	5.00e-76	277.00
IUUC-Pab-098047	Pongo abelii	41.08	1.00e-78	286.00
IUUC-Pop-099587	Populus trichocarpa	29.25	5.00e-94	337.00
IUUC-Pca-100558	Procavia capensis	45.54	3.00e-48	185.00
IUUC-Ppe-101261	Prunus persica	41.91	6.00e-81	293.00
IUUC-Pva-102683	Pteropus vampyrus	40.81	5.00e-76	277.00
IUUC-Pgr-103660	Puccinia graminis	55.10	1.00e-112	399.00
IUUC-Ptt-103900	Puccinia triticina	54.45	4.00e-111	394.00
IUUC-Pte-104209	Pyrenophora teres	40.36	1.00e-85	309.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	40.36	1.00e-85	309.00
IUUC-Rno-105566	Rattus norvegicus	41.08	1.00e-78	286.00
IUUC-Sce-106291	Saccharomyces cerevisiae	34.46	6.00e-81	293.00
IUUC-Sha-107514	Sarcophilus harrisii	39.29	8.00e-68	250.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	34.30	3.00e-113	400.00
IUUC-Spo-108162	Schizosaccharomyces pombe	44.74	2.00e-98	351.00
IUUC-Ssl-108629	Sclerotinia sclerotiorum	40.14	6.00e-26	110.00
IUUC-Smo-109186	Selaginella moellendorffii	38.93	3.00e-76	278.00
IUUC-Sit-109980	Setaria italica	37.76	4.00e-80	291.00
IUUC-Sly-111547	Solanum lycopersicum	36.89	3.00e-79	288.00
IUUC-Stu-112705	Solanum tuberosum	40.54	5.00e-79	287.00
IUUC-Sar-113222	Sorex araneus	38.68	2.00e-65	242.00
IUUC-Sbi-114272	Sorghum bicolor	42.71	2.00e-80	291.00
IUUC-Sre-115061	Sporisorium reilianum	45.96	3.00e-113	401.00
IUUC-Ssc-116364	Sus scrofa	40.96	2.00e-75	275.00
IUUC-Tgu-116645	Taeniopygia guttata	41.71	9.00e-77	280.00
IUUC-Tru-117590	Takifugu rubripes	39.62	3.00e-77	281.00
IUUC-Tsy-119212	Tarsius syrichta	42.32	2.00e-70	259.00
IUUC-Tni-119915	Tetraodon nigroviridis	39.62	3.00e-77	281.00
IUUC-Tca-121765	Theobroma cacao	40.04	4.00e-82	298.00
IUUC-Tre-121887	Trichoderma reesei	40.86	8.00e-78	283.00
IUUC-Tvi-122262	Trichoderma virens	40.86	4.00e-78	284.00
IUUC-Tae-124148	Triticum aestivum	41.67	5.00e-36	144.00
IUUC-Tur-126483	Triticum urartu	41.46	3.00e-79	288.00
IUUC-Tme-127202	Tuber melanosporum	37.13	5.00e-71	260.00
IUUC-Tbe-127350	Tupaia belangeri	34.05	5.00e-44	171.00
IUUC-Ttr-129077	Tursiops truncatus	38.11	4.00e-69	254.00
IUUC-Uma-129465	Ustilago maydis	46.50	1.00e-114	405.00
IUUC-Vda-129844	Verticillium dahliae	40.82	2.00e-87	315.00
IUUC-Vvi-131397	Vitis vinifera	29.44	6.00e-91	327.00
IUUC-Xtr-132057	Xenopus tropicalis	39.73	2.00e-78	285.00
IUUC-Xma-134139	Xiphophorus maculatus	38.05	8.00e-66	243.00
IUUC-Yli-134424	Yarrowia lipolytica	38.43	3.00e-82	298.00
IUUC-Zma-135839	Zea mays	43.22	2.00e-81	295.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence