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Tag Content
iUUCD ID IUUC-Lch-050474
Ensembl Protein ID ENSLACP00000016983.1
UniProt Accession H3B512; H3B512_LATCH
Genbank Protein ID ENSLACP00000016983
Protein Name Protein HIRA
Genbank Nucleotide ID AFYH01024001
Gene Name HIRA
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSLACG00000014956.1 ENSLACT00000017103.1 ENSLACP00000016983.1
ENSLACG00000014956.1 ENSLACT00000017104.1 ENSLACP00000016984.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.50e-17 62.5 131 160
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           H+++v ++++  +d  l+s+s D+t+ +W+
   Q: 131  HSGDVMDVSWspQDVWLASCSVDNTVVIWN 160
           9**********766999************9 PP
   
Organism Latimeria chalumnae
Functional Description
(View)

Functional Description


     Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
 Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Protein Sequence
(Fasta)
MKLLKPTWVN HNGGKPIFSL DIHPDGTKVA TGGQGEDSGK VVIWNMAPVL KEEDEKNQNI 60
PKMLCQIDNH LACVNCVRWS NNGIYLASGG DDKLIMVWKR AQYIGPSTVF GSSNKLANVE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Lch-050474|E3,WD_repeat|Latimeria chalumnae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCCGTGGGAG GATGAGCGGA ACCGTTGCGC GGTGGGGTGG GGTTTCCGCG GGGAGCCGGC 60
GGCCGTGCTG CACGCTTCCT GTGTTGTGGA GGAGCCGCGC AGGGATGGAG TGGCGGCGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Lch-050474|E3,WD_repeat|Latimeria chalumnae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat
Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001039 Aegilops tauschii 38.77 2.00e-86 313.00
IUUC-Aml-001723 Ailuropoda melanoleuca 76.09 0.00e+00 1444.00
IUUC-Atr-003132 Amborella trichopoda 41.06 2.00e-88 320.00
IUUC-Apl-003197 Anas platyrhynchos 78.82 0.00e+00 1518.00
IUUC-Aca-004733 Anolis carolinensis 76.10 0.00e+00 1462.00
IUUC-Aly-005446 Arabidopsis lyrata 39.59 1.00e-80 294.00
IUUC-Ath-007627 Arabidopsis thaliana 41.62 1.00e-84 308.00
IUUC-Ago-007766 Ashbya gossypii 32.06 2.00e-61 230.00
IUUC-Acl-008104 Aspergillus clavatus 33.76 8.00e-65 242.00
IUUC-Afl-008591 Aspergillus flavus 32.39 9.00e-64 238.00
IUUC-Afu-008781 Aspergillus fumigatus 35.13 3.00e-59 223.00
IUUC-Ani-009272 Aspergillus nidulans 29.08 4.00e-54 206.00
IUUC-Ang-009655 Aspergillus niger 34.18 1.00e-65 244.00
IUUC-Aor-010119 Aspergillus oryzae 32.39 9.00e-64 238.00
IUUC-Ate-010530 Aspergillus terreus 30.43 2.00e-54 207.00
IUUC-Ame-011147 Astyanax mexicanus 85.15 2.00e-50 189.00
IUUC-Bgr-012237 Blumeria graminis 33.33 9.00e-63 235.00
IUUC-Bta-013320 Bos taurus 74.76 0.00e+00 1453.00
IUUC-Bci-013795 Botrytis cinerea 35.43 6.00e-70 259.00
IUUC-Bdi-014075 Brachypodium distachyon 37.28 2.00e-91 330.00
IUUC-Bol-016440 Brassica oleracea 40.61 1.00e-87 317.00
IUUC-Bra-016651 Brassica rapa 40.10 1.00e-87 318.00
IUUC-Cel-018692 Caenorhabditis elegans 37.73 2.00e-73 271.00
IUUC-Cja-018987 Callithrix jacchus 75.40 0.00e+00 1372.00
IUUC-Cfa-020132 Canis familiaris 76.09 0.00e+00 1444.00
IUUC-Cpo-021484 Cavia porcellus 75.53 0.00e+00 1466.00
IUUC-Cre-022846 Chlamydomonas reinhardtii 34.90 3.00e-62 233.00
IUUC-Csa-023081 Chlorocebus sabaeus 76.87 0.00e+00 1462.00
IUUC-Cin-025182 Ciona intestinalis 54.99 4.00e-152 532.00
IUUC-Csv-026154 Ciona savignyi 54.77 2.00e-148 520.00
IUUC-Cgl-026655 Colletotrichum gloeosporioides 30.28 4.00e-66 246.00
IUUC-Cne-026891 Cryptococcus neoformans 40.81 4.00e-84 306.00
IUUC-Cme-027349 Cyanidioschyzon merolae 31.42 2.00e-53 204.00
IUUC-Dre-027655 Danio rerio 69.77 0.00e+00 1348.00
IUUC-Dno-029557 Dasypus novemcinctus 69.70 0.00e+00 917.00
IUUC-Dor-030687 Dipodomys ordii 73.28 0.00e+00 677.00
IUUC-Dse-031334 Dothistroma septosporum 31.39 8.00e-65 242.00
IUUC-Dme-031746 Drosophila melanogaster 54.68 1.00e-156 546.00
IUUC-Ete-032384 Echinops telfairi 71.11 0.00e+00 1340.00
IUUC-Eca-033430 Equus caballus 75.61 0.00e+00 1429.00
IUUC-Fca-036121 Felis catus 75.90 0.00e+00 1442.00
IUUC-Fal-036817 Ficedula albicollis 77.94 0.00e+00 1524.00
IUUC-Fox-037906 Fusarium oxysporum 34.34 1.00e-68 254.00
IUUC-Fso-038409 Fusarium solani 34.83 6.00e-68 252.00
IUUC-Gmo-039151 Gadus morhua 84.41 0.00e+00 691.00
IUUC-Ggr-040016 Gaeumannomyces graminis 35.48 1.00e-70 261.00
IUUC-Gga-040936 Gallus gallus 78.80 0.00e+00 1593.00
IUUC-Gac-041405 Gasterosteus aculeatus 61.48 0.00e+00 1179.00
IUUC-Gma-044252 Glycine max 35.24 3.00e-87 317.00
IUUC-Ggo-045430 Gorilla gorilla 76.99 0.00e+00 1460.00
IUUC-Hsa-046442 Homo sapiens 76.78 0.00e+00 1465.00
IUUC-Hvu-047587 Hordeum vulgare 41.04 1.00e-78 288.00
IUUC-Itr-048910 Ictidomys tridecemlineatus 92.00 5.00e-165 573.00
IUUC-Kpa-049145 Komagataella pastoris 30.82 3.00e-59 223.00
IUUC-Lpe-051209 Leersia perrieri 35.98 7.00e-85 308.00
IUUC-Loc-052119 Lepisosteus oculatus 72.48 0.00e+00 1412.00
IUUC-Lma-053237 Leptosphaeria maculans 35.54 5.00e-69 256.00
IUUC-Laf-053718 Loxodonta africana 76.49 0.00e+00 1466.00
IUUC-Mcc-055621 Macaca mulatta 76.03 0.00e+00 1379.00
IUUC-Meu-055914 Macropus eugenii 70.70 0.00e+00 1321.00
IUUC-Mor-057090 Magnaporthe oryzae 34.45 2.00e-68 254.00
IUUC-Mpo-057364 Magnaporthe poae 35.73 4.00e-72 266.00
IUUC-Mtr-057744 Medicago truncatula 36.12 9.00e-88 318.00
IUUC-Mla-058914 Melampsora laricipopulina 42.03 2.00e-84 306.00
IUUC-Mga-060181 Meleagris gallopavo 76.80 0.00e+00 1531.00
IUUC-Mvi-060432 Microbotryum violaceum 38.11 6.00e-75 276.00
IUUC-Mmr-060871 Microcebus murinus 76.20 0.00e+00 1494.00
IUUC-Mdo-062301 Monodelphis domestica 77.49 0.00e+00 1481.00
IUUC-Mmu-063888 Mus musculus 75.65 0.00e+00 1445.00
IUUC-Mac-065137 Musa acuminata 42.44 4.00e-88 319.00
IUUC-Mpu-066732 Mustela putorius furo 76.09 0.00e+00 1467.00
IUUC-Mlu-067542 Myotis lucifugus 75.79 0.00e+00 1424.00
IUUC-Nfi-068396 Neosartorya fischeri 35.13 3.00e-59 223.00
IUUC-Ncr-068842 Neurospora crassa 32.94 9.00e-70 258.00
IUUC-Nle-070156 Nomascus leucogenys 76.68 0.00e+00 1471.00
IUUC-Opr-070808 Ochotona princeps 74.65 0.00e+00 1161.00
IUUC-Ont-072105 Oreochromis niloticus 68.72 0.00e+00 1342.00
IUUC-Ocu-074962 Oryctolagus cuniculus 76.97 0.00e+00 1453.00
IUUC-Oba-075178 Oryza barthii 37.02 2.00e-90 327.00
IUUC-Obr-076399 Oryza brachyantha 36.40 6.00e-91 328.00
IUUC-Ogu-078797 Oryza glumaepatula 37.02 2.00e-90 327.00
IUUC-Oin-080085 Oryza indica 36.21 1.00e-79 291.00
IUUC-Olo-081048 Oryza longistaminata 41.04 1.00e-67 252.00
IUUC-Ome-081324 Oryza meridionalis 37.02 2.00e-90 327.00
IUUC-Oni-082548 Oryza nivara 37.02 1.00e-90 327.00
IUUC-Opu-084008 Oryza punctata 41.73 4.00e-90 326.00
IUUC-Oru-084339 Oryza rufipogon 37.02 3.00e-90 326.00
IUUC-Osa-085782 Oryza sativa 37.02 3.00e-90 326.00
IUUC-Ola-087302 Oryzias latipes 68.54 0.00e+00 795.00
IUUC-Olu-087611 Ostreococcus lucimarinus 34.63 3.00e-87 316.00
IUUC-Oga-087935 Otolemur garnettii 76.33 0.00e+00 1426.00
IUUC-Oar-089229 Ovis aries 58.00 0.00e+00 904.00
IUUC-Ptr-090715 Pan troglodytes 76.78 0.00e+00 1464.00
IUUC-Pan-092318 Papio anubis 76.06 0.00e+00 1438.00
IUUC-Psi-094053 Pelodiscus sinensis 77.96 0.00e+00 1539.00
IUUC-Pno-094985 Phaeosphaeria nodorum 33.49 1.00e-61 231.00
IUUC-Ppa-095819 Physcomitrella patens 35.05 6.00e-87 315.00
IUUC-Pfo-096857 Poecilia formosa 67.05 0.00e+00 1281.00
IUUC-Pab-098047 Pongo abelii 76.78 0.00e+00 1462.00
IUUC-Pop-099587 Populus trichocarpa 38.06 6.00e-89 322.00
IUUC-Pca-100558 Procavia capensis 75.29 2.00e-164 573.00
IUUC-Ppe-101261 Prunus persica 36.46 9.00e-90 325.00
IUUC-Pva-102683 Pteropus vampyrus 75.53 0.00e+00 1471.00
IUUC-Pgr-103660 Puccinia graminis 40.61 4.00e-77 282.00
IUUC-Ptt-103900 Puccinia triticina 41.99 2.00e-79 290.00
IUUC-Pte-104209 Pyrenophora teres 35.29 1.00e-67 251.00
IUUC-Pyt-104802 Pyrenophora triticirepentis 35.29 6.00e-67 249.00
IUUC-Rno-105566 Rattus norvegicus 75.55 0.00e+00 1461.00
IUUC-Sce-106291 Saccharomyces cerevisiae 32.05 2.00e-62 233.00
IUUC-Sha-107514 Sarcophilus harrisii 73.81 0.00e+00 1369.00
IUUC-Sja-107833 Schizosaccharomyces japonicus 40.96 1.00e-81 297.00
IUUC-Spo-108162 Schizosaccharomyces pombe 39.15 3.00e-79 290.00
IUUC-Ssl-108607 Sclerotinia sclerotiorum 32.18 3.00e-26 113.00
IUUC-Smo-109186 Selaginella moellendorffii 39.75 5.00e-88 319.00
IUUC-Sit-110730 Setaria italica 41.98 2.00e-89 323.00
IUUC-Sly-111547 Solanum lycopersicum 41.73 1.00e-89 324.00
IUUC-Stu-112705 Solanum tuberosum 41.73 1.00e-89 325.00
IUUC-Sar-113222 Sorex araneus 71.39 0.00e+00 1278.00
IUUC-Sbi-114272 Sorghum bicolor 37.38 3.00e-92 333.00
IUUC-Sre-115061 Sporisorium reilianum 33.95 9.00e-77 281.00
IUUC-Ssc-116364 Sus scrofa 74.98 0.00e+00 1468.00
IUUC-Tgu-116645 Taeniopygia guttata 78.72 0.00e+00 1558.00
IUUC-Tru-117590 Takifugu rubripes 67.04 0.00e+00 1289.00
IUUC-Tsy-119212 Tarsius syrichta 75.25 0.00e+00 843.00
IUUC-Tni-119915 Tetraodon nigroviridis 67.09 0.00e+00 1282.00
IUUC-Tca-121765 Theobroma cacao 36.31 1.00e-87 318.00
IUUC-Tre-121887 Trichoderma reesei 33.83 4.00e-61 229.00
IUUC-Tvi-122262 Trichoderma virens 34.08 2.00e-61 231.00
IUUC-Tae-124148 Triticum aestivum 43.55 5.00e-35 142.00
IUUC-Tur-126483 Triticum urartu 41.98 1.00e-90 327.00
IUUC-Tme-127202 Tuber melanosporum 33.76 6.00e-58 219.00
IUUC-Tbe-127350 Tupaia belangeri 72.77 3.00e-164 572.00
IUUC-Ttr-129077 Tursiops truncatus 71.79 0.00e+00 1404.00
IUUC-Uma-129465 Ustilago maydis 34.56 1.00e-78 287.00
IUUC-Vda-129844 Verticillium dahliae 35.00 4.00e-67 249.00
IUUC-Vvi-131397 Vitis vinifera 36.29 8.00e-89 322.00
IUUC-Xtr-132057 Xenopus tropicalis 71.67 0.00e+00 1380.00
IUUC-Xma-134139 Xiphophorus maculatus 67.73 0.00e+00 806.00
IUUC-Yli-134424 Yarrowia lipolytica 31.85 3.00e-65 243.00
IUUC-Zma-135839 Zea mays 36.45 6.00e-89 322.00
Created Date 25-Jun-2017

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