iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089287

Ensembl Protein ID

ENSOARP00000004158.1

UniProt Accession

W5P159; W5P159_SHEEP

Genbank Protein ID

ENSOARP00000004158

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01045721

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000003881.1	ENSOART00000004231.1	ENSOARP00000004158.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-12	46.9	920	953

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t +   d t+ l+sG+ Dg i +WD+ tg
   Q: 920  GHSGAITTVYI-DqTMvLASGGQDGAICLWDVLTG 953
           8********88.446648*************9887 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

RMTLTERLRE KISQAFYNHG LFCASYPIPI ILFTGLCILA CCYPLLKLPL PGTGPVEFTT 60
PVKDYSPPPL TSDHKPGEPN EQPEWYVGPP VAYIQQIFVK SSVSPWHKNL LAVDVFRSPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATGACCC TGACTGAAAG GCTGCGTGAG AAGATATCTC AGGCCTTCTA CAACCATGGG 60
CTGTTCTGTG CGTCCTACCC CATCCCCATC ATTCTCTTCA CGGGGCTCTG CATCTTAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	87.63	0.00e+00	983.00
IUUC-Apl-003294	Anas platyrhynchos	73.36	0.00e+00	917.00
IUUC-Aca-004424	Anolis carolinensis	68.32	0.00e+00	850.00
IUUC-Bta-013478	Bos taurus	91.66	0.00e+00	1186.00
IUUC-Cel-018160	Caenorhabditis elegans	28.46	7.00e-66	246.00
IUUC-Cja-019123	Callithrix jacchus	82.48	0.00e+00	1030.00
IUUC-Cfa-021082	Canis familiaris	87.34	0.00e+00	1097.00
IUUC-Cpo-022477	Cavia porcellus	82.52	0.00e+00	1033.00
IUUC-Csa-023176	Chlorocebus sabaeus	89.59	0.00e+00	1106.00
IUUC-Cin-025490	Ciona intestinalis	41.90	2.00e-76	281.00
IUUC-Csv-026115	Ciona savignyi	40.24	1.00e-120	427.00
IUUC-Dre-028008	Danio rerio	65.42	0.00e+00	826.00
IUUC-Dno-028887	Dasypus novemcinctus	84.47	0.00e+00	1090.00
IUUC-Dor-030467	Dipodomys ordii	91.38	0.00e+00	860.00
IUUC-Dme-032087	Drosophila melanogaster	35.88	2.00e-93	338.00
IUUC-Ete-032372	Echinops telfairi	80.61	7.00e-180	624.00
IUUC-Eca-033896	Equus caballus	87.64	0.00e+00	1120.00
IUUC-Eeu-035099	Erinaceus europaeus	77.47	0.00e+00	933.00
IUUC-Fca-035616	Felis catus	81.43	0.00e+00	994.00
IUUC-Fal-037231	Ficedula albicollis	71.72	0.00e+00	873.00
IUUC-Gmo-039439	Gadus morhua	73.23	0.00e+00	669.00
IUUC-Gac-041516	Gasterosteus aculeatus	67.00	0.00e+00	835.00
IUUC-Hsa-046674	Homo sapiens	86.09	0.00e+00	1112.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	86.23	0.00e+00	1112.00
IUUC-Lch-049689	Latimeria chalumnae	67.26	0.00e+00	840.00
IUUC-Loc-051906	Lepisosteus oculatus	88.59	3.00e-76	276.00
IUUC-Laf-053795	Loxodonta africana	85.71	0.00e+00	1120.00
IUUC-Mcc-055502	Macaca mulatta	86.23	0.00e+00	1114.00
IUUC-Mga-059805	Meleagris gallopavo	75.35	0.00e+00	942.00
IUUC-Mmr-060997	Microcebus murinus	86.79	0.00e+00	1117.00
IUUC-Mdo-062940	Monodelphis domestica	77.35	0.00e+00	992.00
IUUC-Mmu-063255	Mus musculus	85.40	0.00e+00	1101.00
IUUC-Mpu-066158	Mustela putorius furo	86.51	0.00e+00	1113.00
IUUC-Mlu-067201	Myotis lucifugus	80.61	0.00e+00	1016.00
IUUC-Nle-069145	Nomascus leucogenys	85.95	0.00e+00	1106.00
IUUC-Opr-070797	Ochotona princeps	76.50	0.00e+00	932.00
IUUC-Ont-071553	Oreochromis niloticus	66.99	0.00e+00	842.00
IUUC-Ocu-074598	Oryctolagus cuniculus	85.26	0.00e+00	1070.00
IUUC-Ola-086650	Oryzias latipes	85.19	6.00e-111	392.00
IUUC-Pan-092004	Papio anubis	86.23	0.00e+00	1113.00
IUUC-Psi-093028	Pelodiscus sinensis	71.84	0.00e+00	927.00
IUUC-Pma-094145	Petromyzon marinus	58.33	0.00e+00	697.00
IUUC-Pfo-096320	Poecilia formosa	66.16	0.00e+00	837.00
IUUC-Pab-097862	Pongo abelii	86.23	0.00e+00	1115.00
IUUC-Pca-100862	Procavia capensis	71.84	0.00e+00	896.00
IUUC-Pva-103050	Pteropus vampyrus	86.09	0.00e+00	1076.00
IUUC-Rno-105852	Rattus norvegicus	85.12	0.00e+00	1101.00
IUUC-Sha-107312	Sarcophilus harrisii	76.78	0.00e+00	984.00
IUUC-Sar-113311	Sorex araneus	88.75	0.00e+00	658.00
IUUC-Ssc-116356	Sus scrofa	88.04	0.00e+00	1167.00
IUUC-Tgu-116896	Taeniopygia guttata	75.31	9.00e-85	308.00
IUUC-Tru-118197	Takifugu rubripes	68.70	0.00e+00	819.00
IUUC-Tni-119823	Tetraodon nigroviridis	66.37	0.00e+00	812.00
IUUC-Ttr-129164	Tursiops truncatus	88.73	0.00e+00	1149.00
IUUC-Xtr-132819	Xenopus tropicalis	65.95	0.00e+00	864.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence