KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0339--Growth factor
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal

IPR029034--Cystine-knot_cytokine
IPR001839--TGF-b_C
IPR001111--TGF-b_propeptide
IPR016319--TGF-beta
IPR015615--TGF-beta-rel
IPR003939--TGFb1
IPR017948--TGFb_CS

PS00250--TGF_BETA_1
PS51362--TGF_BETA_2

PF00019--TGF_beta
PF00688--TGFb_propeptide

PR01423--TGFBETA
PR01424--TGFBETA1

SM00204--TGFB

GO:0072562--C:blood microparticle
GO:0009986--C:cell surface
GO:0005737--C:cytoplasm
GO:0005615--C:extracellular space
GO:0005902--C:microvillus
GO:0005634--C:nucleus
GO:0005578--C:proteinaceous extracellular matrix
GO:0003823--F:antigen binding
GO:0001948--F:glycoprotein binding
GO:0043539--F:protein serine/threonine kinase activator activity
GO:0034713--F:type I transforming growth factor beta receptor binding
GO:0005114--F:type II transforming growth factor beta receptor binding
GO:0034714--F:type III transforming growth factor beta receptor binding
GO:0002460--P:adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0006754--P:ATP biosynthetic process
GO:0060751--P:branch elongation involved in mammary gland duct branching
GO:0007050--P:cell cycle arrest
GO:0016049--P:cell growth
GO:0045216--P:cell-cell junction organization
GO:0006874--P:cellular calcium ion homeostasis
GO:0071407--P:cellular response to organic cyclic compound
GO:0071560--P:cellular response to transforming growth factor beta stimulus
GO:0002062--P:chondrocyte differentiation
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:1990402--P:embryonic liver development
GO:0007492--P:endoderm development
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0001837--P:epithelial to mesenchymal transition
GO:0019049--P:evasion or tolerance of host defenses by virus
GO:0085029--P:extracellular matrix assembly
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0060325--P:face morphogenesis
GO:0008354--P:germ cell migration
GO:0003179--P:heart valve morphogenesis
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0030214--P:hyaluronan catabolic process
GO:0006954--P:inflammatory response
GO:0070306--P:lens fiber cell differentiation
GO:0031663--P:lipopolysaccharide-mediated signaling pathway
GO:0048535--P:lymph node development
GO:0060744--P:mammary gland branching involved in thelarche
GO:0000165--P:MAPK cascade
GO:0031293--P:membrane protein intracellular domain proteolysis
GO:0007093--P:mitotic cell cycle checkpoint
GO:0032943--P:mononuclear cell proliferation
GO:0043011--P:myeloid dendritic cell differentiation
GO:0043537--P:negative regulation of blood vessel endothelial cell migration
GO:0045786--P:negative regulation of cell cycle
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0022408--P:negative regulation of cell-cell adhesion
GO:0008156--P:negative regulation of DNA replication
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0045599--P:negative regulation of fat cell differentiation
GO:0010629--P:negative regulation of gene expression
GO:0060965--P:negative regulation of gene silencing by miRNA
GO:1900126--P:negative regulation of hyaluronan biosynthetic process
GO:0032700--P:negative regulation of interleukin-17 production
GO:0010936--P:negative regulation of macrophage cytokine production
GO:0045930--P:negative regulation of mitotic cell cycle
GO:0045662--P:negative regulation of myoblast differentiation
GO:0030279--P:negative regulation of ossification
GO:1903799--P:negative regulation of production of miRNAs involved in gene silencing by miRNA
GO:1903077--P:negative regulation of protein localization to plasma membrane
GO:0001933--P:negative regulation of protein phosphorylation
GO:0048642--P:negative regulation of skeletal muscle tissue development
GO:0042130--P:negative regulation of T cell proliferation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0001843--P:neural tube closure
GO:0007219--P:Notch signaling pathway
GO:0014003--P:oligodendrocyte development
GO:0043932--P:ossification involved in bone remodeling
GO:0060389--P:pathway-restricted SMAD protein phosphorylation
GO:0006796--P:phosphate-containing compound metabolic process
GO:0043536--P:positive regulation of blood vessel endothelial cell migration
GO:0030501--P:positive regulation of bone mineralization
GO:2000727--P:positive regulation of cardiac muscle cell differentiation
GO:0071158--P:positive regulation of cell cycle arrest
GO:0030335--P:positive regulation of cell migration
GO:0008284--P:positive regulation of cell proliferation
GO:0032270--P:positive regulation of cellular protein metabolic process
GO:0050921--P:positive regulation of chemotaxis
GO:0032967--P:positive regulation of collagen biosynthetic process
GO:0010718--P:positive regulation of epithelial to mesenchymal transition
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0010763--P:positive regulation of fibroblast migration
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0035066--P:positive regulation of histone acetylation
GO:0031065--P:positive regulation of histone deacetylation
GO:0032740--P:positive regulation of interleukin-17 production
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:0043406--P:positive regulation of MAP kinase activity
GO:1901666--P:positive regulation of NAD+ ADP-ribosyltransferase activity
GO:0042482--P:positive regulation of odontogenesis
GO:0010862--P:positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:1902895--P:positive regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0031334--P:positive regulation of protein complex assembly
GO:0035307--P:positive regulation of protein dephosphorylation
GO:0042307--P:positive regulation of protein import into nucleus
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0001934--P:positive regulation of protein phosphorylation
GO:0050714--P:positive regulation of protein secretion
GO:1903911--P:positive regulation of receptor clustering
GO:0045591--P:positive regulation of regulatory T cell differentiation
GO:0060391--P:positive regulation of SMAD protein import into nucleus
GO:0032930--P:positive regulation of superoxide anion generation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0043117--P:positive regulation of vascular permeability
GO:0006611--P:protein export from nucleus
GO:0000060--P:protein import into nucleus, translocation
GO:0043491--P:protein kinase B signaling
GO:0032801--P:receptor catabolic process
GO:2000249--P:regulation of actin cytoskeleton reorganization
GO:0060762--P:regulation of branching involved in mammary gland duct morphogenesis
GO:0061035--P:regulation of cartilage development
GO:0032667--P:regulation of interleukin-23 production
GO:0002028--P:regulation of sodium ion transport
GO:0017015--P:regulation of transforming growth factor beta receptor signaling pathway
GO:0045066--P:regulatory T cell differentiation
GO:0070723--P:response to cholesterol
GO:0032355--P:response to estradiol
GO:0032570--P:response to progesterone
GO:0009611--P:response to wounding
GO:0007435--P:salivary gland morphogenesis
GO:0007183--P:SMAD protein complex assembly
GO:0007184--P:SMAD protein import into nucleus
GO:0043029--P:T cell homeostasis
GO:0002513--P:tolerance induction to self antigen
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:1905313--P:transforming growth factor beta receptor signaling pathway involved in heart development
GO:0001657--P:ureteric bud development
GO:0001570--P:vasculogenesis
GO:0055010--P:ventricular cardiac muscle tissue morphogenesis