iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066128

Ensembl Protein ID

ENSMPUP00000006159.1

UniProt Accession

M3Y4A8; M3Y4A8_MUSPF

Genbank Protein ID

ENSMPUP00000006159

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AEYP01059930

Gene Name

UCHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000006212.1	ENSMPUT00000006267.1	ENSMPUP00000006159.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	95.00	6.00e-102	367.00	IUUC-Hsa-045820
DUB/UCH	95.00	6.00e-102	367.00	IUUC-Hsa-045820
UBD/Other/Other	95.00	6.00e-102	367.00	IUUC-Hsa-045820

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MQLKPMEINP EMLNKVLARL GVAGQWRFAD VLGLEEEALG SVPAPACALL LLFPLTAQHE 60
NFRKKQIEEL KGQAVSPKVY FMKQTIGNSC GTIGIIHAVA NNQDKLEFED GSVLKQFLSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCTCA AACCGATGGA GATTAACCCC GAGGTGAGCG TCAGGTGCAT CGCTGCTCGG 60
GGACCGCATT GCTGAGAGTC AGCCCAGGCC AGGTAGCTGC CTCGATGACC GGCTTTATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR030297--UCHL1

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:1904115--C:axon cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0044306--C:neuron projection terminus
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0016874--F:ligase activity
GO:0008242--F:omega peptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007628--P:adult walking behavior
GO:0007412--P:axon target recognition
GO:0019896--P:axonal transport of mitochondrion
GO:0008283--P:cell proliferation
GO:0042755--P:eating behavior
GO:0048747--P:muscle fiber development
GO:0043407--P:negative regulation of MAP kinase activity
GO:0050905--P:neuromuscular process
GO:0016579--P:protein deubiquitination
GO:0002931--P:response to ischemia
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001376	Ailuropoda melanoleuca	79.83	9.00e-101	359.00
IUUC-Apl-003693	Anas platyrhynchos	68.16	5.00e-78	283.00
IUUC-Aca-004716	Anolis carolinensis	73.13	1.00e-87	315.00
IUUC-Ame-011806	Astyanax mexicanus	64.18	2.00e-72	264.00
IUUC-Bta-013521	Bos taurus	79.91	2.00e-101	361.00
IUUC-Cja-018752	Callithrix jacchus	94.53	1.00e-102	365.00
IUUC-Cfa-020442	Canis familiaris	97.01	1.00e-104	372.00
IUUC-Cpo-021723	Cavia porcellus	90.85	3.00e-81	293.00
IUUC-Csa-023626	Chlorocebus sabaeus	95.00	1.00e-103	368.00
IUUC-Cho-024548	Choloepus hoffmanni	86.11	6.00e-41	160.00
IUUC-Dre-027854	Danio rerio	60.89	9.00e-71	259.00
IUUC-Dno-029325	Dasypus novemcinctus	96.00	3.00e-105	374.00
IUUC-Dor-030114	Dipodomys ordii	93.50	2.00e-112	397.00
IUUC-Ete-033092	Echinops telfairi	74.00	3.00e-82	297.00
IUUC-Eca-033854	Equus caballus	96.64	1.00e-66	244.00
IUUC-Eeu-034493	Erinaceus europaeus	92.00	1.00e-99	355.00
IUUC-Fal-036693	Ficedula albicollis	72.19	6.00e-79	286.00
IUUC-Gmo-038848	Gadus morhua	59.70	2.00e-69	254.00
IUUC-Gga-041078	Gallus gallus	73.13	2.00e-87	315.00
IUUC-Gac-042064	Gasterosteus aculeatus	59.20	9.00e-68	249.00
IUUC-Ggo-044827	Gorilla gorilla	95.00	6.00e-104	369.00
IUUC-Hsa-045820	Homo sapiens	95.00	6.00e-104	369.00
IUUC-Itr-048496	Ictidomys tridecemlineatus	96.50	5.00e-105	373.00
IUUC-Lch-050121	Latimeria chalumnae	71.14	2.00e-84	305.00
IUUC-Loc-052342	Lepisosteus oculatus	67.82	3.00e-79	287.00
IUUC-Laf-053916	Loxodonta africana	93.10	3.00e-102	364.00
IUUC-Mcc-054838	Macaca mulatta	95.00	1.00e-103	368.00
IUUC-Meu-056478	Macropus eugenii	88.00	2.00e-106	378.00
IUUC-Mga-059878	Meleagris gallopavo	71.65	1.00e-81	295.00
IUUC-Mdo-062544	Monodelphis domestica	87.50	2.00e-96	344.00
IUUC-Mmu-063300	Mus musculus	96.50	9.00e-115	405.00
IUUC-Mlu-067778	Myotis lucifugus	95.00	5.00e-113	399.00
IUUC-Nle-069686	Nomascus leucogenys	95.00	7.00e-104	369.00
IUUC-Opr-070535	Ochotona princeps	75.50	2.00e-85	307.00
IUUC-Ont-071510	Oreochromis niloticus	59.20	6.00e-68	249.00
IUUC-Ocu-074590	Oryctolagus cuniculus	95.00	2.00e-104	371.00
IUUC-Oga-089013	Otolemur garnettii	79.91	1.00e-100	358.00
IUUC-Oar-089861	Ovis aries	79.91	2.00e-101	361.00
IUUC-Ptr-091536	Pan troglodytes	93.00	1.00e-101	361.00
IUUC-Pan-092909	Papio anubis	95.00	1.00e-103	368.00
IUUC-Psi-093818	Pelodiscus sinensis	78.11	8.00e-91	325.00
IUUC-Pfo-097335	Poecilia formosa	56.16	7.00e-67	246.00
IUUC-Pab-098048	Pongo abelii	95.00	6.00e-104	369.00
IUUC-Pca-100818	Procavia capensis	72.82	3.00e-67	247.00
IUUC-Pva-102954	Pteropus vampyrus	95.00	2.00e-99	354.00
IUUC-Rno-105966	Rattus norvegicus	96.50	9.00e-115	405.00
IUUC-Sha-107111	Sarcophilus harrisii	86.62	6.00e-74	269.00
IUUC-Sar-113190	Sorex araneus	68.83	3.00e-25	106.00
IUUC-Ssc-115908	Sus scrofa	76.24	5.00e-86	310.00
IUUC-Tgu-117465	Taeniopygia guttata	68.09	8.00e-73	266.00
IUUC-Tsy-119561	Tarsius syrichta	74.50	9.00e-83	299.00
IUUC-Tbe-128048	Tupaia belangeri	92.96	2.00e-78	284.00
IUUC-Ttr-128494	Tursiops truncatus	95.00	5.00e-102	363.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence