iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117465

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

ABQF01015585

Gene Name

UCHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008638.1	ENSTGUT00000009024.1	ENSTGUP00000008927.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	70.14	5.00e-85	311.00	IUUC-Hsa-045820
DUB/UCH	70.14	5.00e-85	311.00	IUUC-Hsa-045820
UBD/Other/Other	70.14	5.00e-85	311.00	IUUC-Hsa-045820

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

QVLSRLGVGP GWRFVDVLGF EDEALRAVPT PACALLLLFP LTEQHENFRK QQTEKIKDQE 60
ISSKVYFLKQ TVSNSCGTIG LIHAVANNKD KLKLEEGSAL KKFLDETADL SPEERAKHLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTGCTGT CCCGCCTCGG GGTGGGTCCT GGCTGGCGCT TCGTGGACGT ACTGGGCTTC 60
GAGGATGAGG CACTGCGCGC CGTGCCGACC CCGGCCTGCG CGCTGCTGCT GCTGTTCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR030297--UCHL1

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:1904115--C:axon cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0044306--C:neuron projection terminus
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0016874--F:ligase activity
GO:0008242--F:omega peptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007628--P:adult walking behavior
GO:0007412--P:axon target recognition
GO:0019896--P:axonal transport of mitochondrion
GO:0008283--P:cell proliferation
GO:0042755--P:eating behavior
GO:0048747--P:muscle fiber development
GO:0043407--P:negative regulation of MAP kinase activity
GO:0050905--P:neuromuscular process
GO:0016579--P:protein deubiquitination
GO:0002931--P:response to ischemia
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001376	Ailuropoda melanoleuca	56.33	2.00e-70	258.00
IUUC-Apl-003693	Anas platyrhynchos	84.83	2.00e-102	364.00
IUUC-Aca-004716	Anolis carolinensis	74.88	3.00e-94	337.00
IUUC-Ame-011806	Astyanax mexicanus	60.48	2.00e-72	264.00
IUUC-Bta-013521	Bos taurus	57.50	2.00e-72	265.00
IUUC-Cja-018752	Callithrix jacchus	70.28	7.00e-76	275.00
IUUC-Cfa-020442	Canis familiaris	71.09	1.00e-77	281.00
IUUC-Cpo-021723	Cavia porcellus	69.05	2.00e-66	244.00
IUUC-Csa-023626	Chlorocebus sabaeus	69.19	2.00e-75	274.00
IUUC-Cho-024548	Choloepus hoffmanni	76.92	2.00e-29	121.00
IUUC-Dre-027854	Danio rerio	60.66	3.00e-72	263.00
IUUC-Dno-029325	Dasypus novemcinctus	69.19	6.00e-76	276.00
IUUC-Dor-030114	Dipodomys ordii	67.77	5.00e-84	303.00
IUUC-Ete-033092	Echinops telfairi	67.07	9.00e-64	235.00
IUUC-Eeu-034493	Erinaceus europaeus	70.50	2.00e-73	267.00
IUUC-Fal-036693	Ficedula albicollis	95.26	2.00e-116	410.00
IUUC-Gmo-038848	Gadus morhua	56.78	7.00e-63	232.00
IUUC-Gga-041078	Gallus gallus	90.52	1.00e-110	391.00
IUUC-Gac-042064	Gasterosteus aculeatus	60.95	8.00e-73	265.00
IUUC-Ggo-044827	Gorilla gorilla	70.14	1.00e-76	278.00
IUUC-Hsa-045820	Homo sapiens	70.14	1.00e-76	278.00
IUUC-Itr-048496	Ictidomys tridecemlineatus	68.72	3.00e-75	273.00
IUUC-Lch-050121	Latimeria chalumnae	65.07	7.00e-82	296.00
IUUC-Loc-052342	Lepisosteus oculatus	63.38	2.00e-78	284.00
IUUC-Laf-053916	Loxodonta africana	68.72	9.00e-76	275.00
IUUC-Mcc-054838	Macaca mulatta	69.19	2.00e-75	274.00
IUUC-Meu-056478	Macropus eugenii	69.19	9.00e-86	308.00
IUUC-Mga-059878	Meleagris gallopavo	90.52	1.00e-110	391.00
IUUC-Mdo-062544	Monodelphis domestica	68.90	3.00e-74	270.00
IUUC-Mmu-063300	Mus musculus	69.19	2.00e-85	307.00
IUUC-Mpu-066128	Mustela putorius furo	68.09	6.00e-63	233.00
IUUC-Mlu-067778	Myotis lucifugus	69.67	3.00e-86	310.00
IUUC-Nle-069686	Nomascus leucogenys	69.67	2.00e-76	277.00
IUUC-Opr-070535	Ochotona princeps	67.66	4.00e-65	240.00
IUUC-Ont-071510	Oreochromis niloticus	58.57	9.00e-72	262.00
IUUC-Ocu-074590	Oryctolagus cuniculus	68.25	1.00e-74	271.00
IUUC-Ola-087552	Oryzias latipes	56.74	4.00e-68	250.00
IUUC-Oga-089013	Otolemur garnettii	56.67	1.00e-71	261.00
IUUC-Oar-089861	Ovis aries	57.50	2.00e-72	265.00
IUUC-Ptr-091536	Pan troglodytes	70.14	1.00e-76	278.00
IUUC-Pan-092909	Papio anubis	69.19	2.00e-75	274.00
IUUC-Psi-093818	Pelodiscus sinensis	79.62	1.00e-97	348.00
IUUC-Pfo-097335	Poecilia formosa	60.19	1.00e-73	268.00
IUUC-Pab-098048	Pongo abelii	70.14	1.00e-76	278.00
IUUC-Pca-100818	Procavia capensis	56.83	1.00e-43	168.00
IUUC-Pva-102954	Pteropus vampyrus	70.14	1.00e-74	271.00
IUUC-Pyt-104587	Pyrenophora triticirepentis	34.74	2.00e-28	118.00
IUUC-Rno-105966	Rattus norvegicus	69.19	2.00e-85	307.00
IUUC-Sar-113190	Sorex araneus	48.28	3.00e-20	89.70
IUUC-Tru-118565	Takifugu rubripes	60.98	1.00e-70	258.00
IUUC-Tsy-119561	Tarsius syrichta	67.66	1.00e-63	235.00
IUUC-Tbe-128048	Tupaia belangeri	68.86	4.00e-66	242.00
IUUC-Ttr-128494	Tursiops truncatus	69.38	2.00e-74	271.00
IUUC-Xtr-132286	Xenopus tropicalis	64.59	3.00e-78	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence